Bayesian performance

Size: px
Start display at page:

Download "Bayesian performance"

Transcription

1 Bayesian performance In this section we will study the statistical properties of Bayesian estimates. Major topics include: The likelihood principle Decision theory/bayes rules Shrinkage estimators Frequentist properties of Bayesian estimators ST740 (2) Bayes Performance - Part 1 Page 1

2 The likelihood principle In a Bayesian analysis, everything we know about the parameters is summarized by the posterior (likelihood x prior). Is it true that classical methods only use the likelihood? Likelihood principle: Once the data are observed, the likelihood contains all the information in the data about the parameters. The p-value can violate the likelihood principle because it depends on both the data and unobserved events. Example (Lindley and Phillips): A coin with P(heads)=θ is flipped 12 times and we observe 9 heads. Now test H 0 : θ = 0.5 versus H 1 : θ > 0.5. Analysis 1: Analysis 2: ST740 (2) Bayes Performance - Part 1 Page 2

3 The likelihood principle A Bayesian analysis adheres to the likelihood principle. For example, in both analysis Do you think the likelihood principle is important? ST740 (2) Bayes Performance - Part 1 Page 3

4 Calibrated Bayes Now we ll begin to study the frequentist properties of Bayesian estimators (unbiasedness, consistency, etc.). First, should we (Bayesians) really care about frequentist properties of estimators? ST740 (2) Bayes Performance - Part 1 Page 4

5 Calibrated Bayes Some quotes from Little (2011). Calibrated Bayes, for Statistics in General, and Missing Data in Particular. Statistical Science, 26, Little: To summarize, Bayesian statistics is strong for inference under an assumed model, but relatively weak for the development and assessment of models. Frequentist statistics provides useful tools for model development and assessment, but has weaknesses for inference under an assumed model. If this summary is accepted, then the natural compromise is to use frequentist methods for model development and assessment, and Bayesian methods for inference under a model. This capitalizes on the strengths of both paradigms, and is the essence of the approach known as Calibrated Bayes. Rubin: The applied statistician should be Bayesian in principle and calibrated to the real world in practice - appropriate frequency calculations help to define such a tie...frequency calculations are useful for making Bayesian statements scientific, scientific in the sense of capable of being shown wrong by empirical test; here the technique is the calibration of Bayesian probabilities to the frequencies of actual events. ST740 (2) Bayes Performance - Part 1 Page 5

6 In a Bayesian analysis all inference is based on the posterior distribution p(θ y). What is the best one-number summary of the posterior, ˆθ, to be used as the estimator? This depends on the situation, and in particular, on the penalty associated with different types of errors (e.g., maybe overestimation is way worse than underestimation). We will use decision theory to form estimators with good properties. ST740 (2) Bayes Performance - Part 1 Page 6

7 We need a definition of best to get started. Let θ 0 be the true value of the parameter and ˆθ(y) be our estimator (perhaps the posterior mean). The loss function l[θ 0, ˆθ(y)] is cost associated with estimating θ to be ˆθ(y) when the truth is θ 0. Examples: ST740 (2) Bayes Performance - Part 1 Page 7

8 The loss function l[θ 0, ˆθ(y)] depends on both the true value (θ 0 ) and the data (via ˆθ). We need to average over one or both of these to compare methods. Bayesian analysis is conditioned on the data, so we average over θ 0. Risk = l[θ, ˆθ(y)]w(θ)dθ. Which values of θ 0 should be weighted the highest? Bayesian risk = The Bayes rule is the estimator ˆθ(y) that minimizes Bayesian risk. ST740 (2) Bayes Performance - Part 1 Page 8

9 Under squared error loss l[θ 0, ˆθ(y)] = [θ 0 ˆθ(y)] 2, the Bayes rule is ST740 (2) Bayes Performance - Part 1 Page 9

10 Under absolute loss l[θ 0, ˆθ(y)] = θ 0 ˆθ(y), the Bayes rule is Under zero/one loss l[θ 0, ˆθ(y)] = I[θ 0 = ˆθ(y)], the Bayes rule is Hypothesis testing: Say θ = 0 if H 0 is true and θ = 1 if H 1 is true. Give the Bayes rule under the loss l[θ 0, ˆθ(y)] = λ 1 I[θ 0 = 0, ˆθ(y) = 1] + λ 2 I[θ 0 = 1, ˆθ(y) = 0]. How to pick λ 1 and λ 2? ST740 (2) Bayes Performance - Part 1 Page 10

11 We ve seen loss function for point estimation and hypothesis testing, which loss functions are appropriate for interval estimation? ST740 (2) Bayes Performance - Part 1 Page 11

ST440/550: Applied Bayesian Statistics. (10) Frequentist Properties of Bayesian Methods

ST440/550: Applied Bayesian Statistics. (10) Frequentist Properties of Bayesian Methods (10) Frequentist Properties of Bayesian Methods Calibrated Bayes So far we have discussed Bayesian methods as being separate from the frequentist approach However, in many cases methods with frequentist

More information

Introduction to Bayesian Analysis 1

Introduction to Bayesian Analysis 1 Biostats VHM 801/802 Courses Fall 2005, Atlantic Veterinary College, PEI Henrik Stryhn Introduction to Bayesian Analysis 1 Little known outside the statistical science, there exist two different approaches

More information

Introduction. Patrick Breheny. January 10. The meaning of probability The Bayesian approach Preview of MCMC methods

Introduction. Patrick Breheny. January 10. The meaning of probability The Bayesian approach Preview of MCMC methods Introduction Patrick Breheny January 10 Patrick Breheny BST 701: Bayesian Modeling in Biostatistics 1/25 Introductory example: Jane s twins Suppose you have a friend named Jane who is pregnant with twins

More information

MS&E 226: Small Data

MS&E 226: Small Data MS&E 226: Small Data Lecture 10: Introduction to inference (v2) Ramesh Johari ramesh.johari@stanford.edu 1 / 17 What is inference? 2 / 17 Where did our data come from? Recall our sample is: Y, the vector

More information

How to Choose the Wrong Model. Scott L. Zeger Department of Biostatistics Johns Hopkins Bloomberg School

How to Choose the Wrong Model. Scott L. Zeger Department of Biostatistics Johns Hopkins Bloomberg School How to Choose the Wrong Model Scott L. Zeger Department of Biostatistics Johns Hopkins Bloomberg School What is a model? Questions Which is the best (true, right) model? How can you choose a useful model?

More information

Learning from data when all models are wrong

Learning from data when all models are wrong Learning from data when all models are wrong Peter Grünwald CWI / Leiden Menu Two Pictures 1. Introduction 2. Learning when Models are Seriously Wrong Joint work with John Langford, Tim van Erven, Steven

More information

Practical Bayesian Design and Analysis for Drug and Device Clinical Trials

Practical Bayesian Design and Analysis for Drug and Device Clinical Trials Practical Bayesian Design and Analysis for Drug and Device Clinical Trials p. 1/2 Practical Bayesian Design and Analysis for Drug and Device Clinical Trials Brian P. Hobbs Plan B Advisor: Bradley P. Carlin

More information

Cognitive Modeling. Lecture 12: Bayesian Inference. Sharon Goldwater. School of Informatics University of Edinburgh

Cognitive Modeling. Lecture 12: Bayesian Inference. Sharon Goldwater. School of Informatics University of Edinburgh Cognitive Modeling Lecture 12: Bayesian Inference Sharon Goldwater School of Informatics University of Edinburgh sgwater@inf.ed.ac.uk February 18, 20 Sharon Goldwater Cognitive Modeling 1 1 Prediction

More information

Coherence and calibration: comments on subjectivity and objectivity in Bayesian analysis (Comment on Articles by Berger and by Goldstein)

Coherence and calibration: comments on subjectivity and objectivity in Bayesian analysis (Comment on Articles by Berger and by Goldstein) Bayesian Analysis (2006) 1, Number 3, pp. 423 428 Coherence and calibration: comments on subjectivity and objectivity in Bayesian analysis (Comment on Articles by Berger and by Goldstein) David Draper

More information

A Brief Introduction to Bayesian Statistics

A Brief Introduction to Bayesian Statistics A Brief Introduction to Statistics David Kaplan Department of Educational Psychology Methods for Social Policy Research and, Washington, DC 2017 1 / 37 The Reverend Thomas Bayes, 1701 1761 2 / 37 Pierre-Simon

More information

What is a probability? Two schools in statistics: frequentists and Bayesians.

What is a probability? Two schools in statistics: frequentists and Bayesians. Faculty of Life Sciences Frequentist and Bayesian statistics Claus Ekstrøm E-mail: ekstrom@life.ku.dk Outline 1 Frequentists and Bayesians What is a probability? Interpretation of results / inference 2

More information

INTRODUCTION TO BAYESIAN REASONING

INTRODUCTION TO BAYESIAN REASONING International Journal of Technology Assessment in Health Care, 17:1 (2001), 9 16. Copyright c 2001 Cambridge University Press. Printed in the U.S.A. INTRODUCTION TO BAYESIAN REASONING John Hornberger Roche

More information

BAYESIAN HYPOTHESIS TESTING WITH SPSS AMOS

BAYESIAN HYPOTHESIS TESTING WITH SPSS AMOS Sara Garofalo Department of Psychiatry, University of Cambridge BAYESIAN HYPOTHESIS TESTING WITH SPSS AMOS Overview Bayesian VS classical (NHST or Frequentist) statistical approaches Theoretical issues

More information

Genome-Wide Localization of Protein-DNA Binding and Histone Modification by a Bayesian Change-Point Method with ChIP-seq Data

Genome-Wide Localization of Protein-DNA Binding and Histone Modification by a Bayesian Change-Point Method with ChIP-seq Data Genome-Wide Localization of Protein-DNA Binding and Histone Modification by a Bayesian Change-Point Method with ChIP-seq Data Haipeng Xing, Yifan Mo, Will Liao, Michael Q. Zhang Clayton Davis and Geoffrey

More information

Discussion. Risto Lehtonen Introduction

Discussion. Risto Lehtonen Introduction Journal of Official Statistics, Vol. 28, No. 3, 2012, pp. 353 357 Discussion Risto Lehtonen 1 1. Introduction In his inspiring article, Professor Little presents a fresh view of statistical inference by

More information

Bayesian Inference. Review. Breast Cancer Screening. Breast Cancer Screening. Breast Cancer Screening

Bayesian Inference. Review. Breast Cancer Screening. Breast Cancer Screening. Breast Cancer Screening STAT 101 Dr. Kari Lock Morgan Review What is the deinition of the p- value? a) P(statistic as extreme as that observed if H 0 is true) b) P(H 0 is true if statistic as extreme as that observed) SETION

More information

Meta-analysis of few small studies in small populations and rare diseases

Meta-analysis of few small studies in small populations and rare diseases Meta-analysis of few small studies in small populations and rare diseases Christian Röver 1, Beat Neuenschwander 2, Simon Wandel 2, Tim Friede 1 1 Department of Medical Statistics, University Medical Center

More information

How to Choose the Wrong Model. Scott L. Zeger Department of Biostatistics Johns Hopkins Bloomberg School

How to Choose the Wrong Model. Scott L. Zeger Department of Biostatistics Johns Hopkins Bloomberg School This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this

More information

Bayesian Inference Bayes Laplace

Bayesian Inference Bayes Laplace Bayesian Inference Bayes Laplace Course objective The aim of this course is to introduce the modern approach to Bayesian statistics, emphasizing the computational aspects and the differences between the

More information

Bayesian Methods LABORATORY. Lesson 1: Jan Software: R. Bayesian Methods p.1/20

Bayesian Methods LABORATORY. Lesson 1: Jan Software: R. Bayesian Methods p.1/20 Bayesian Methods LABORATORY Lesson 1: Jan 24 2002 Software: R Bayesian Methods p.1/20 The R Project for Statistical Computing http://www.r-project.org/ R is a language and environment for statistical computing

More information

UNLOCKING VALUE WITH DATA SCIENCE BAYES APPROACH: MAKING DATA WORK HARDER

UNLOCKING VALUE WITH DATA SCIENCE BAYES APPROACH: MAKING DATA WORK HARDER UNLOCKING VALUE WITH DATA SCIENCE BAYES APPROACH: MAKING DATA WORK HARDER 2016 DELIVERING VALUE WITH DATA SCIENCE BAYES APPROACH - MAKING DATA WORK HARDER The Ipsos MORI Data Science team increasingly

More information

Using Item Response Theory To Rate (Not Only) Programmers

Using Item Response Theory To Rate (Not Only) Programmers Using Item Response Theory To Rate (Not Only) Programmers Katedra informatiky Fakulta matematiky, fyziky a informatiky Univerzita Komenského Bratislava, Slovensko 10 th of August,

More information

Bayes Theorem Application: Estimating Outcomes in Terms of Probability

Bayes Theorem Application: Estimating Outcomes in Terms of Probability Bayes Theorem Application: Estimating Outcomes in Terms of Probability The better the estimates, the better the outcomes. It s true in engineering and in just about everything else. Decisions and judgments

More information

Bayesian Adjustments for Misclassified Data. Lawrence Joseph

Bayesian Adjustments for Misclassified Data. Lawrence Joseph Bayesian Adjustments for Misclassified Data Lawrence Joseph Bayesian Adjustments for Misclassified Data Lawrence Joseph Marcel Behr, Patrick Bélisle, Sasha Bernatsky, Nandini Dendukuri, Theresa Gyorkos,

More information

Response to the ASA s statement on p-values: context, process, and purpose

Response to the ASA s statement on p-values: context, process, and purpose Response to the ASA s statement on p-values: context, process, purpose Edward L. Ionides Alexer Giessing Yaacov Ritov Scott E. Page Departments of Complex Systems, Political Science Economics, University

More information

Bayesian and Frequentist Approaches

Bayesian and Frequentist Approaches Bayesian and Frequentist Approaches G. Jogesh Babu Penn State University http://sites.stat.psu.edu/ babu http://astrostatistics.psu.edu All models are wrong But some are useful George E. P. Box (son-in-law

More information

Bayesian Inference. Thomas Nichols. With thanks Lee Harrison

Bayesian Inference. Thomas Nichols. With thanks Lee Harrison Bayesian Inference Thomas Nichols With thanks Lee Harrison Attention to Motion Paradigm Results Attention No attention Büchel & Friston 1997, Cereb. Cortex Büchel et al. 1998, Brain - fixation only -

More information

Bayesian Adjustments for Misclassified Data. Lawrence Joseph

Bayesian Adjustments for Misclassified Data. Lawrence Joseph Bayesian Adjustments for Misclassified Data Lawrence Joseph Marcel Behr, Patrick Bélisle, Sasha Bernatsky, Nandini Dendukuri, Theresa Gyorkos, Martin Ladouceur, Elham Rahme, Kevin Schwartzman, Allison

More information

Hierarchical Bayesian Modeling of Individual Differences in Texture Discrimination

Hierarchical Bayesian Modeling of Individual Differences in Texture Discrimination Hierarchical Bayesian Modeling of Individual Differences in Texture Discrimination Timothy N. Rubin (trubin@uci.edu) Michael D. Lee (mdlee@uci.edu) Charles F. Chubb (cchubb@uci.edu) Department of Cognitive

More information

What is probability. A way of quantifying uncertainty. Mathematical theory originally developed to model outcomes in games of chance.

What is probability. A way of quantifying uncertainty. Mathematical theory originally developed to model outcomes in games of chance. Outline What is probability Another definition of probability Bayes Theorem Prior probability; posterior probability How Bayesian inference is different from what we usually do Example: one species or

More information

Att vara eller inte vara (en Bayesian)?... Sherlock-conundrum

Att vara eller inte vara (en Bayesian)?... Sherlock-conundrum Att vara eller inte vara (en Bayesian)?... Sherlock-conundrum (Thanks/blame to Google Translate) Gianluca Baio University College London Department of Statistical Science g.baio@ucl.ac.uk http://www.ucl.ac.uk/statistics/research/statistics-health-economics/

More information

Calibrated Bayes: A Bayes/Frequentist Roadmap

Calibrated Bayes: A Bayes/Frequentist Roadmap Calibrated Bayes: A Bayes/Frequentist Roadmap Roderick LITTLE The lack of an agreed inferential basis for statistics makes life interesting for academic statisticians, but at the price of negative implications

More information

STATISTICAL INFERENCE 1 Richard A. Johnson Professor Emeritus Department of Statistics University of Wisconsin

STATISTICAL INFERENCE 1 Richard A. Johnson Professor Emeritus Department of Statistics University of Wisconsin STATISTICAL INFERENCE 1 Richard A. Johnson Professor Emeritus Department of Statistics University of Wisconsin Key words : Bayesian approach, classical approach, confidence interval, estimation, randomization,

More information

Understanding Statistics for Research Staff!

Understanding Statistics for Research Staff! Statistics for Dummies? Understanding Statistics for Research Staff! Those of us who DO the research, but not the statistics. Rachel Enriquez, RN PhD Epidemiologist Why do we do Clinical Research? Epidemiology

More information

A Case Study: Two-sample categorical data

A Case Study: Two-sample categorical data A Case Study: Two-sample categorical data Patrick Breheny January 31 Patrick Breheny BST 701: Bayesian Modeling in Biostatistics 1/43 Introduction Model specification Continuous vs. mixture priors Choice

More information

Doing Thousands of Hypothesis Tests at the Same Time. Bradley Efron Stanford University

Doing Thousands of Hypothesis Tests at the Same Time. Bradley Efron Stanford University Doing Thousands of Hypothesis Tests at the Same Time Bradley Efron Stanford University 1 Simultaneous Hypothesis Testing 1980: Simultaneous Statistical Inference (Rupert Miller) 2, 3,, 20 simultaneous

More information

How to use the Lafayette ESS Report to obtain a probability of deception or truth-telling

How to use the Lafayette ESS Report to obtain a probability of deception or truth-telling Lafayette Tech Talk: How to Use the Lafayette ESS Report to Obtain a Bayesian Conditional Probability of Deception or Truth-telling Raymond Nelson The Lafayette ESS Report is a useful tool for field polygraph

More information

UW Biostatistics Working Paper Series

UW Biostatistics Working Paper Series UW Biostatistics Working Paper Series Year 2005 Paper 242 Bayesian Evaluation of Group Sequential Clinical Trial Designs Scott S. Emerson University of Washington Daniel L. Gillen University of California,

More information

Missing data. Patrick Breheny. April 23. Introduction Missing response data Missing covariate data

Missing data. Patrick Breheny. April 23. Introduction Missing response data Missing covariate data Missing data Patrick Breheny April 3 Patrick Breheny BST 71: Bayesian Modeling in Biostatistics 1/39 Our final topic for the semester is missing data Missing data is very common in practice, and can occur

More information

Intelligent Systems. Discriminative Learning. Parts marked by * are optional. WS2013/2014 Carsten Rother, Dmitrij Schlesinger

Intelligent Systems. Discriminative Learning. Parts marked by * are optional. WS2013/2014 Carsten Rother, Dmitrij Schlesinger Intelligent Systems Discriminative Learning Parts marked by * are optional 30/12/2013 WS2013/2014 Carsten Rother, Dmitrij Schlesinger Discriminative models There exists a joint probability distribution

More information

Meta-analysis of two studies in the presence of heterogeneity with applications in rare diseases

Meta-analysis of two studies in the presence of heterogeneity with applications in rare diseases Meta-analysis of two studies in the presence of heterogeneity with applications in rare diseases Christian Röver 1, Tim Friede 1, Simon Wandel 2 and Beat Neuenschwander 2 1 Department of Medical Statistics,

More information

"PRINCIPLES OF PHYLOGENETICS: ECOLOGY AND EVOLUTION"

PRINCIPLES OF PHYLOGENETICS: ECOLOGY AND EVOLUTION "PRINCIPLES OF PHYLOGENETICS: ECOLOGY AND EVOLUTION" Integrative Biology 200B University of California, Berkeley Lab for Jan 25, 2011, Introduction to Statistical Thinking A. Concepts: A way of making

More information

3. Fixed-sample Clinical Trial Design

3. Fixed-sample Clinical Trial Design 3. Fixed-sample Clinical Trial Design 3. Fixed-sample clinical trial design 3.1 On choosing the sample size 3.2 Frequentist evaluation of a fixed-sample trial 3.3 Bayesian evaluation of a fixed-sample

More information

Part 1: Modelling and Estimation. Maximum Likelihood Estimation. A nonparametric regression smoother. Social Science and Parametric Models

Part 1: Modelling and Estimation. Maximum Likelihood Estimation. A nonparametric regression smoother. Social Science and Parametric Models Part 1: Modelling and Estimation Maximum Likelihood Estimation Charles H. Franklin What is a model How do we estimate its parameters? What are the properties of the estimator? franklin@polisci.wisc.edu

More information

Bayesian Confidence Intervals for Means and Variances of Lognormal and Bivariate Lognormal Distributions

Bayesian Confidence Intervals for Means and Variances of Lognormal and Bivariate Lognormal Distributions Bayesian Confidence Intervals for Means and Variances of Lognormal and Bivariate Lognormal Distributions J. Harvey a,b, & A.J. van der Merwe b a Centre for Statistical Consultation Department of Statistics

More information

An Exercise in Bayesian Econometric Analysis Probit and Linear Probability Models

An Exercise in Bayesian Econometric Analysis Probit and Linear Probability Models Utah State University DigitalCommons@USU All Graduate Plan B and other Reports Graduate Studies 5-1-2014 An Exercise in Bayesian Econometric Analysis Probit and Linear Probability Models Brooke Jeneane

More information

Excursion 1: How to Tell What s True about Statistical Inference

Excursion 1: How to Tell What s True about Statistical Inference Excursion 1: How to Tell What s True about Statistical Inference Tour I: Beyond Probabilism and Performance (1.1) If we re to get beyond the statistics wars, we need to understand the arguments behind

More information

Sections 10.7 and 10.9

Sections 10.7 and 10.9 Sections 10.7 and 10.9 Timothy Hanson Department of Statistics, University of South Carolina Stat 205: Elementary Statistics for the Biological and Life Sciences 1 / 24 10.7 confidence interval for p 1

More information

Dynamic Causal Modeling

Dynamic Causal Modeling Dynamic Causal Modeling Hannes Almgren, Frederik van de Steen, Daniele Marinazzo daniele.marinazzo@ugent.be @dan_marinazzo Model of brain mechanisms Neural populations Neural model Interactions between

More information

Natural Scene Statistics and Perception. W.S. Geisler

Natural Scene Statistics and Perception. W.S. Geisler Natural Scene Statistics and Perception W.S. Geisler Some Important Visual Tasks Identification of objects and materials Navigation through the environment Estimation of motion trajectories and speeds

More information

Reasoning with Uncertainty. Reasoning with Uncertainty. Bayes Rule. Often, we want to reason from observable information to unobservable information

Reasoning with Uncertainty. Reasoning with Uncertainty. Bayes Rule. Often, we want to reason from observable information to unobservable information Reasoning with Uncertainty Reasoning with Uncertainty Often, we want to reason from observable information to unobservable information We want to calculate how our prior beliefs change given new available

More information

15.301/310, Managerial Psychology Prof. Dan Ariely Recitation 8: T test and ANOVA

15.301/310, Managerial Psychology Prof. Dan Ariely Recitation 8: T test and ANOVA 15.301/310, Managerial Psychology Prof. Dan Ariely Recitation 8: T test and ANOVA Statistics does all kinds of stuff to describe data Talk about baseball, other useful stuff We can calculate the probability.

More information

Undesirable Optimality Results in Multiple Testing? Charles Lewis Dorothy T. Thayer

Undesirable Optimality Results in Multiple Testing? Charles Lewis Dorothy T. Thayer Undesirable Optimality Results in Multiple Testing? Charles Lewis Dorothy T. Thayer 1 Intuitions about multiple testing: - Multiple tests should be more conservative than individual tests. - Controlling

More information

Introduction to screening tests. Tim Hanson Department of Statistics University of South Carolina April, 2011

Introduction to screening tests. Tim Hanson Department of Statistics University of South Carolina April, 2011 Introduction to screening tests Tim Hanson Department of Statistics University of South Carolina April, 2011 1 Overview: 1. Estimating test accuracy: dichotomous tests. 2. Estimating test accuracy: continuous

More information

Introduction to Machine Learning. Katherine Heller Deep Learning Summer School 2018

Introduction to Machine Learning. Katherine Heller Deep Learning Summer School 2018 Introduction to Machine Learning Katherine Heller Deep Learning Summer School 2018 Outline Kinds of machine learning Linear regression Regularization Bayesian methods Logistic Regression Why we do this

More information

Statistical Decision Theory and Bayesian Analysis

Statistical Decision Theory and Bayesian Analysis Statistical Decision Theory and Bayesian Analysis Chapter 3: Prior Information and Subjective Probability Lili MOU moull12@sei.pku.edu.cn http://sei.pku.edu.cn/ moull12 11 MayApril 2015 Reference 3, James

More information

Hierarchy of Statistical Goals

Hierarchy of Statistical Goals Hierarchy of Statistical Goals Ideal goal of scientific study: Deterministic results Determine the exact value of a ment or population parameter Prediction: What will the value of a future observation

More information

Model calibration and Bayesian methods for probabilistic projections

Model calibration and Bayesian methods for probabilistic projections ETH Zurich Reto Knutti Model calibration and Bayesian methods for probabilistic projections Reto Knutti, IAC ETH Toy model Model: obs = linear trend + noise(variance, spectrum) 1) Short term predictability,

More information

An Introduction to Bayesian Statistics

An Introduction to Bayesian Statistics An Introduction to Bayesian Statistics Robert Weiss Department of Biostatistics UCLA Fielding School of Public Health robweiss@ucla.edu Sept 2015 Robert Weiss (UCLA) An Introduction to Bayesian Statistics

More information

Using historical data for Bayesian sample size determination

Using historical data for Bayesian sample size determination Using historical data for Bayesian sample size determination Author: Fulvio De Santis, J. R. Statist. Soc. A (2007) 170, Part 1, pp. 95 113 Harvard Catalyst Journal Club: December 7 th 2016 Kush Kapur,

More information

BAYESIAN ESTIMATORS OF THE LOCATION PARAMETER OF THE NORMAL DISTRIBUTION WITH UNKNOWN VARIANCE

BAYESIAN ESTIMATORS OF THE LOCATION PARAMETER OF THE NORMAL DISTRIBUTION WITH UNKNOWN VARIANCE BAYESIAN ESTIMATORS OF THE LOCATION PARAMETER OF THE NORMAL DISTRIBUTION WITH UNKNOWN VARIANCE Janet van Niekerk* 1 and Andriette Bekker 1 1 Department of Statistics, University of Pretoria, 0002, Pretoria,

More information

arxiv: v1 [math.st] 8 Jun 2012

arxiv: v1 [math.st] 8 Jun 2012 Comments on Confidence distribution, the frequentist distribution estimator of a parameter a review by Min-ge Xie and Kesar Singh arxiv:1206.1708v1 [math.st] 8 Jun 2012 Christian P. Robert Université Paris-Dauphine,

More information

Computer Age Statistical Inference. Algorithms, Evidence, and Data Science. BRADLEY EFRON Stanford University, California

Computer Age Statistical Inference. Algorithms, Evidence, and Data Science. BRADLEY EFRON Stanford University, California Computer Age Statistical Inference Algorithms, Evidence, and Data Science BRADLEY EFRON Stanford University, California TREVOR HASTIE Stanford University, California ggf CAMBRIDGE UNIVERSITY PRESS Preface

More information

INHERENT DIFFICULTIES WITH ACTIVE CONTROL EQUIVALENCE STUDIES*

INHERENT DIFFICULTIES WITH ACTIVE CONTROL EQUIVALENCE STUDIES* STATISTICS IN MEDICINE, VOL. 12, 2367-2375 (1993) INHERENT DIFFICULTIES WITH ACTIVE CONTROL EQUIVALENCE STUDIES* STEPHEN SENN Medical Department, Pharmaceutical Division, CIBA-GEIG Y AG, 4002 Bade, Switzerland

More information

Midterm project due next Wednesday at 2 PM

Midterm project due next Wednesday at 2 PM Course Business Midterm project due next Wednesday at 2 PM Please submit on CourseWeb Next week s class: Discuss current use of mixed-effects models in the literature Short lecture on effect size & statistical

More information

Sample Size Considerations. Todd Alonzo, PhD

Sample Size Considerations. Todd Alonzo, PhD Sample Size Considerations Todd Alonzo, PhD 1 Thanks to Nancy Obuchowski for the original version of this presentation. 2 Why do Sample Size Calculations? 1. To minimize the risk of making the wrong conclusion

More information

T-Statistic-based Up&Down Design for Dose-Finding Competes Favorably with Bayesian 4-parameter Logistic Design

T-Statistic-based Up&Down Design for Dose-Finding Competes Favorably with Bayesian 4-parameter Logistic Design T-Statistic-based Up&Down Design for Dose-Finding Competes Favorably with Bayesian 4-parameter Logistic Design James A. Bolognese, Cytel Nitin Patel, Cytel Yevgen Tymofyeyef, Merck Inna Perevozskaya, Wyeth

More information

Bayesian Model Averaging for Propensity Score Analysis

Bayesian Model Averaging for Propensity Score Analysis Multivariate Behavioral Research, 49:505 517, 2014 Copyright C Taylor & Francis Group, LLC ISSN: 0027-3171 print / 1532-7906 online DOI: 10.1080/00273171.2014.928492 Bayesian Model Averaging for Propensity

More information

Introductory Statistical Inference with the Likelihood Function

Introductory Statistical Inference with the Likelihood Function Introductory Statistical Inference with the Likelihood Function Charles A. Rohde Introductory Statistical Inference with the Likelihood Function 123 Charles A. Rohde Bloomberg School of Health Johns Hopkins

More information

Cognitive Science and Bayes. The main question. Several views. Introduction. The main question Several views Examples. The heuristics view

Cognitive Science and Bayes. The main question. Several views. Introduction. The main question Several views Examples. The heuristics view To Bayes or not to Bayes Radboud University Nijmegen 07-04- 09 The original Bayesian view Are people Bayesian estimators? Or more precisely: should cognitive judgments be viewed as following optimal statistical

More information

Sampling, Modeling and Measurement Error in Inference from Clinical Text

Sampling, Modeling and Measurement Error in Inference from Clinical Text Sampling, Modeling and Measurement Error in Inference from Clinical Text Bob Carpenter Columbia University, Department of Statistics LingPipe, Inc. ICML 2011 Workshop: Learning from Unstructured Clinical

More information

Bayes theorem describes the probability of an event, based on prior knowledge of conditions that might be related to the event.

Bayes theorem describes the probability of an event, based on prior knowledge of conditions that might be related to the event. Bayes theorem Bayes' Theorem is a theorem of probability theory originally stated by the Reverend Thomas Bayes. It can be seen as a way of understanding how the probability that a theory is true is affected

More information

The Wellbeing Course. Resource: Mental Skills. The Wellbeing Course was written by Professor Nick Titov and Dr Blake Dear

The Wellbeing Course. Resource: Mental Skills. The Wellbeing Course was written by Professor Nick Titov and Dr Blake Dear The Wellbeing Course Resource: Mental Skills The Wellbeing Course was written by Professor Nick Titov and Dr Blake Dear About Mental Skills This resource introduces three mental skills which people find

More information

Intro to Probability Instructor: Alexandre Bouchard

Intro to Probability Instructor: Alexandre Bouchard www.stat.ubc.ca/~bouchard/courses/stat302-sp2017-18/ Intro to Probability Instructor: Alexandre Bouchard Plan for today: Bayesian inference 101 Decision diagram for non equally weighted problems Bayes

More information

For general queries, contact

For general queries, contact Much of the work in Bayesian econometrics has focused on showing the value of Bayesian methods for parametric models (see, for example, Geweke (2005), Koop (2003), Li and Tobias (2011), and Rossi, Allenby,

More information

The Frequentist Implications of Optional Stopping on Bayesian Hypothesis Tests

The Frequentist Implications of Optional Stopping on Bayesian Hypothesis Tests The Frequentist Implications of Optional Stopping on Bayesian Hypothesis Tests Adam N. Sanborn Thomas T. Hills Department of Psychology, University of Warwick Abstract Null hypothesis significance testing

More information

Bayesian Analysis by Simulation

Bayesian Analysis by Simulation 408 Resampling: The New Statistics CHAPTER 25 Bayesian Analysis by Simulation Simple Decision Problems Fundamental Problems In Statistical Practice Problems Based On Normal And Other Distributions Conclusion

More information

Bayesians methods in system identification: equivalences, differences, and misunderstandings

Bayesians methods in system identification: equivalences, differences, and misunderstandings Bayesians methods in system identification: equivalences, differences, and misunderstandings Johan Schoukens and Carl Edward Rasmussen ERNSI 217 Workshop on System Identification Lyon, September 24-27,

More information

Lecture Outline Biost 517 Applied Biostatistics I. Statistical Goals of Studies Role of Statistical Inference

Lecture Outline Biost 517 Applied Biostatistics I. Statistical Goals of Studies Role of Statistical Inference Lecture Outline Biost 517 Applied Biostatistics I Scott S. Emerson, M.D., Ph.D. Professor of Biostatistics University of Washington Statistical Inference Role of Statistical Inference Hierarchy of Experimental

More information

Citation for published version (APA): Ebbes, P. (2004). Latent instrumental variables: a new approach to solve for endogeneity s.n.

Citation for published version (APA): Ebbes, P. (2004). Latent instrumental variables: a new approach to solve for endogeneity s.n. University of Groningen Latent instrumental variables Ebbes, P. IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document

More information

Standing Between a Bayesian and a Frequentist: An Emperical Bayes Exploration of Movies, Baseball, and Williams College.

Standing Between a Bayesian and a Frequentist: An Emperical Bayes Exploration of Movies, Baseball, and Williams College. Standing Between a Bayesian and a Frequentist: An Emperical Bayes Exploration of Movies, Baseball, and Williams College Arthur Berg Pennsylvania State University Bayesian and Frequentist Representatives

More information

Bayesian vs Frequentist

Bayesian vs Frequentist Bayesian vs Frequentist Xia, Ziqing (Purple Mountain Observatory) Duan, Kaikai (Purple Montain Observatory) Centelles Chuliá, Salvador (Ific, valencia) Srivastava, Rahul (Ific, Valencia) Taken from xkcd

More information

Signal Detection Theory and Bayesian Modeling

Signal Detection Theory and Bayesian Modeling Signal Detection Theory and Bayesian Modeling COGS 202: Computational Modeling of Cognition Omar Shanta, Shuai Tang, Gautam Reddy, Reina Mizrahi, Mehul Shah Detection Theory and Psychophysics: A Review

More information

Acknowledgements. Section 1: The Science of Clinical Investigation. Scott Zeger. Marie Diener-West. ICTR Leadership / Team

Acknowledgements. Section 1: The Science of Clinical Investigation. Scott Zeger. Marie Diener-West. ICTR Leadership / Team INTRODUCTION TO CLINICAL RESEARCH Scientific Concepts for Clinical Research Karen Bandeen-Roche, Ph.D. July 15, 2013 Scott Zeger Acknowledgements Marie Diener-West ICTR Leadership / Team July 2013 JHU

More information

A Bayesian Account of Reconstructive Memory

A Bayesian Account of Reconstructive Memory Hemmer, P. & Steyvers, M. (8). A Bayesian Account of Reconstructive Memory. In V. Sloutsky, B. Love, and K. McRae (Eds.) Proceedings of the 3th Annual Conference of the Cognitive Science Society. Mahwah,

More information

Agenetic disorder serious, perhaps fatal without

Agenetic disorder serious, perhaps fatal without ACADEMIA AND CLINIC The First Positive: Computing Positive Predictive Value at the Extremes James E. Smith, PhD; Robert L. Winkler, PhD; and Dennis G. Fryback, PhD Computing the positive predictive value

More information

Beyond Subjective and Objective in Statistics

Beyond Subjective and Objective in Statistics June 05 Foundations of Statistics Other objectivity vs. subjectivity issues The current discourse is not helpful. Objectivity and Subjectivity in Statistics Starting point: how are these terms used in

More information

The Bayesian flip Correcting the prosecutor s fallacy

The Bayesian flip Correcting the prosecutor s fallacy legal The Bayesian flip Correcting the prosecutor s fallacy From mammogram results to the O. J. Simpson trial and null hypothesis significance testing William P. Skorupski and Howard Wainer demonstrate

More information

ROLE OF RANDOMIZATION IN BAYESIAN ANALYSIS AN EXPOSITORY OVERVIEW by Jayanta K. Ghosh Purdue University and I.S.I. Technical Report #05-04

ROLE OF RANDOMIZATION IN BAYESIAN ANALYSIS AN EXPOSITORY OVERVIEW by Jayanta K. Ghosh Purdue University and I.S.I. Technical Report #05-04 ROLE OF RANDOMIZATION IN BAYESIAN ANALYSIS AN EXPOSITORY OVERVIEW by Jayanta K. Ghosh Purdue University and I.S.I. Technical Report #05-04 Department of Statistics Purdue University West Lafayette, IN

More information

I. Introduction and Data Collection B. Sampling. 1. Bias. In this section Bias Random Sampling Sampling Error

I. Introduction and Data Collection B. Sampling. 1. Bias. In this section Bias Random Sampling Sampling Error I. Introduction and Data Collection B. Sampling In this section Bias Random Sampling Sampling Error 1. Bias Bias a prejudice in one direction (this occurs when the sample is selected in such a way that

More information

PHILOSOPHY OF STATISTICS: AN INTRODUCTION

PHILOSOPHY OF STATISTICS: AN INTRODUCTION PHILOSOPHY OF STATISTICS: AN INTRODUCTION Prasanta S. Bandyopadhyay and Malcolm R. Forster 1 PHILOSOPHY, STATISTICS, AND PHILOSOPHY OF STATISTICS The expression philosophy of statistics contains two key

More information

Illustrating Frequentist and Bayesian Statistics in Oceanography 1

Illustrating Frequentist and Bayesian Statistics in Oceanography 1 Illustrating Frequentist and Bayesian Statistics in Oceanography 1 George Casella Cornell University ABSTRACT Both frequentist and Bayesian methodologies provides means for a statistical solution to a

More information

Macroeconometric Analysis. Chapter 1. Introduction

Macroeconometric Analysis. Chapter 1. Introduction Macroeconometric Analysis Chapter 1. Introduction Chetan Dave David N. DeJong 1 Background The seminal contribution of Kydland and Prescott (1982) marked the crest of a sea change in the way macroeconomists

More information

A COMPARISON OF BAYESIAN MCMC AND MARGINAL MAXIMUM LIKELIHOOD METHODS IN ESTIMATING THE ITEM PARAMETERS FOR THE 2PL IRT MODEL

A COMPARISON OF BAYESIAN MCMC AND MARGINAL MAXIMUM LIKELIHOOD METHODS IN ESTIMATING THE ITEM PARAMETERS FOR THE 2PL IRT MODEL International Journal of Innovative Management, Information & Production ISME Internationalc2010 ISSN 2185-5439 Volume 1, Number 1, December 2010 PP. 81-89 A COMPARISON OF BAYESIAN MCMC AND MARGINAL MAXIMUM

More information

Section 1: The Science of Clinical Investigation

Section 1: The Science of Clinical Investigation INTRODUCTION TO CLINICAL RESEARCH Scientific Concepts for Clinical Research Scott L. Zeger, Ph.D. July 14, 2014 Section 1: The Science of Clinical Investigation 1. Platonic model: science as the search

More information

Representativeness heuristics

Representativeness heuristics Representativeness heuristics 1-1 People judge probabilities by the degree to which A is representative of B, that is, by the degree to which A resembles B. A can be sample and B a population, or A can

More information

Bayesian Models for Combining Data Across Subjects and Studies in Predictive fmri Data Analysis

Bayesian Models for Combining Data Across Subjects and Studies in Predictive fmri Data Analysis Bayesian Models for Combining Data Across Subjects and Studies in Predictive fmri Data Analysis Thesis Proposal Indrayana Rustandi April 3, 2007 Outline Motivation and Thesis Preliminary results: Hierarchical

More information

On Test Scores (Part 2) How to Properly Use Test Scores in Secondary Analyses. Structural Equation Modeling Lecture #12 April 29, 2015

On Test Scores (Part 2) How to Properly Use Test Scores in Secondary Analyses. Structural Equation Modeling Lecture #12 April 29, 2015 On Test Scores (Part 2) How to Properly Use Test Scores in Secondary Analyses Structural Equation Modeling Lecture #12 April 29, 2015 PRE 906, SEM: On Test Scores #2--The Proper Use of Scores Today s Class:

More information

Bayesian Models for Combining Data Across Domains and Domain Types in Predictive fmri Data Analysis (Thesis Proposal)

Bayesian Models for Combining Data Across Domains and Domain Types in Predictive fmri Data Analysis (Thesis Proposal) Bayesian Models for Combining Data Across Domains and Domain Types in Predictive fmri Data Analysis (Thesis Proposal) Indrayana Rustandi Computer Science Department Carnegie Mellon University March 26,

More information