Manual of Stem Cell and Bone Marrow Transplantation
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1 Manual of Stem Cell and Bone Marrow Transplantation in this web service
2 in this web service
3 Manual of Stem Cell and Bone Marrow Transplantation Joseph H. Antin Harvard Medical School and Dana-Farber Brigham and Women s Cancer Center, Boston, MA Deborah Yolin Raley Dana-Farber Brigham and Women s Cancer Center, Boston, MA in this web service
4 University Printing House, Cambridge CB2 8BS, United Kingdom is part of the University of Cambridge. It furthers the University s mission by disseminating knowledge in the pursuit of education, learning and research at the highest international levels of excellence. Information on this title: / This publication is in copyright. Subject to statutory exception and to the provisions of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of. First published 2013 Reprinted 2014 Printing in the United Kingdom by TJ International Ltd. Padstow Cornwall A catalogue record for this publication is available from the British Library Library of Congress Cataloguing in Publication data Antin, Joseph H., author. Manual of stem cell and bone marrow transplantation / Joseph H. Antin, Deborah Yolin Raley. 2nd edition. p. ; cm. Includes bibliographical references and index. ISBN (pbk.) I. Raley, Deborah Yolin, author. II. Dana-Farber Cancer Institute. III. Title. [DNLM: 1. Stem Cell Transplantation. 2. Bone Marrow Transplantation. QU 325] RD dc ISBN Paperback has no responsibility for the persistence or accuracy of URLs for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate. Every effort has been made in preparing this book to provide accurate and up-to-date information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every effort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors and publishers therefore disclaim all liability for direct or consequential damages resulting from the use of material contained in this book. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan to use. in this web service
5 Contents Acknowledgments Contributor viii vii 1 Rationale for transplantation 1 2 Types of transplantation 3 3 Human leukocyte antigen matching in allogeneic transplantation 6 4 Stem cell source 9 5 Pretransplant evaluation and counseling of patient and donor 15 6 Conditioning regimens 21 7 Stem cell infusion 31 8 ABO compatibility 34 9 Engraftment Preventative care Transplant-related complications Overview of acute and chronic graft-versus-host disease Acute graft-versus-host disease and staging Graft-versus-host disease prophylactic regimens Treatment guidelines for acute graft-versus-host disease Chronic graft-versus-host disease Engraftment syndrome Infectious disease Graft rejection and failure Gastrointestinal complications Oral health in stem cell transplantation 130 Nathaniel S. Treister 22 Pulmonary complications Veno-occlusive disease Special transfusion-related situations 167 v in this web service
6 vi Contents 25 Cardiovascular complications Neurologic complications Cystitis Donor lymphocyte infusion Transplantation: regulation and accreditation 181 Index 182 in this web service
7 Acknowledgments We would like to acknowledge the contributions, thoughtful reading, and critical insights of our colleagues: Philippe Armand, MD Theona Arsenault Lindsay Baden, MD Bonnie Campbell, BS, RPh Corey Cutler, MD Cara Dejong, RD Lauren Fay, RD Brett Glotzbecker, MD Richard Kaufman, MD David Kubiak, PharmD, BCPS Francisco Marty, MD Robert Soiffer, MD Nathaniel S. Treister, DMD, DMSc vii in this web service
8 Contributor Nathaniel S. Treister Harvard School of Dental Medicine and Division of Oral Medicine and Dentistry at Brigham and Women s Hospital, Boston, MA, USA viii in this web service
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