Welcome, Introduction and Objectives of the Workshop

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1 Welcome, Introduction and Objectives of the Workshop Nutrition for the Ageing Brain: Towards Evidence for an Optimal Diet 3 July 2014 Prof. Diána Bánáti Executive and Scientific Director, ILSI Europe 1

2 Age of the population (years) The age distribution of the population in developed regions < < Source: UN (2012) 2

3 Age of the population (years) The age distribution of the population in developed regions < < Source: UN (2012) 3

4 Millions Population aged 60 years or over by development region, Least developed countries Less developed regions, excl least developed countries More developed regions x Source: UN (2013)

5 Ageing and dementia Ageing Healthy ageing Unhealthy ageing Dementia 5

6 Risk factors of healthy ageing Modifyable risk factors Unhealthy diet Physical inactivity Tabacco/alcohol/drugs Stress Intermediate risk factors Cardiovascular disease Obesity Diabetes Pulmonary disease Mental illness Non-modifyable risk factors Age Family history Genetics 6

7 Millions Growing number of people with dementia High-income Low- and middle-income Source: WHO (2012) 7

8 Nutrition and mental performance What we eat or refrain from eating, may have an important impact on our cognitive abilities. Food and nutrients can benefit brain functions. Great opportunities remain for innovation to optimise neurodevelopment and reduce risk of cognitive decline.

9 Nutrition and mental performance Nutrition impacts cognition Optimisation of neurodevelopment Prevention of neurodegeneration and cognitive decline Subjective effects 9

10 Recommendation of WHO for the future WHO recommends: Making dementia a national public health and social care priority worldwide Improving public and professional attitudes to, and understanding of, dementia. Improving access to education. Neurodevelopment is a little-understood area with significant long-term implications. More research needed to identify modifiable risk factors. 10

11 Recommendation of WHO for the future WHO recommends: Making dementia a national public health and social care priority worldwide Improving public and professional attitudes to, and understanding of, dementia. Improving access to education. Neurodevelopment is a little-understood area with significant long-term implications. PROMOTION of optimal neurodevelopment and PREVENTION of neurodegeneration and cognitive decline are critical More research needed to identify modifiable risk factors. 11

12 ILSI Europe ILSI Europe is a science-driven organisation Building a bridge between science and today s public health challenges Peer-reviewed publications and scientific meetings (workshops, symposia) 12

13 ILSI Europe s mission SCIENCE-DRIVEN organisation Addressing COMPLEX scientific issues Thanks to renowned EXPERTS and scientists With COMPLEMENTARY experiences 13

14 Driven by Science Science-driven approach Stringent scientific review of our portfolio and new activities by SAC and BOD Scientific outputs Peer-reviewed articles in high impact factor journals Workshops and symposia with best scientists in the fields ILSI Europe sessions at key conferences At least 50% academics in EGs, SAC and BOD Close collaboration with key organisations (e.g. WHO, FAO, EC, national authorities, etc) Wide network 375 publications More than 14,000 citations h-index 53 14

15 Tripartite Approach Applying state-of-the-art science to topics of common concern, the collaboration between our experts provides balanced, practical and high quality contributions to public health science. Epidemiologists Clinicians Research & Development Toxicologists Food Safety Nutritionists Public Health EC Regulatory Affairs Consumer Science National Authorities 15

16 A network of highly renowned experts Collaboration with 250 non-industry experts from 27 countries worldwide Active network of 450 scientists Communication to 8,700 stakeholders Member of the ILSI family (14 branches and 3 entities) Additional network of 415 scientists through the EU-projects we are involved in 16

17 ILSI Europe Membership in Members Abbott Nutrition Ajinomoto Europe Arla Foods Barilla G&R Fratelli BASF SE Bayer S.A.S. Bunge Europe Campbell Soup Company Cargill Chr Hansen Coca-Cola Europe Cosucra Groupe Warcoing Danone Dow Europe DSM DuPont de Nemours Firmenich General Mills Givaudan International Indoor Biotechnologies Ingredion Incorporated Institut Mérieux International Nutrition Company Johnson & Johnson EAME Kao Corporation Kellogg Europe Kikkoman Foods Europe Lonza Luigi Lavazza Mars McDonald's Europe Mead Johnson Nutrition Merck Consumer Healthcare Mondelēz International Monsanto Europe Nestlé Newtricious Nexira PepsiCo International Pfizer Consumer Healthcare Pierre Fabre Dermo Cosmétique Premier Foods Procter & Gamble Puratos Group Red Bull Roquette Group Royal Friesland Campina Rudolf Wild Sanofi-Aventis R&D Schwabegroup Sensus Soremartec Italia Ferrero Group Südzucker/BENEO Group Swiss Quality Testing Services Syngenta Crop Protection Tate & Lyle Ingredients Tereos Syral Tetra Pak Research Ülker Bisküvi Unilever Yakult Europe WALA Heilmittel 17 Updated on 05 June 2014

18 Nutrition and Mental Performance Task Force

19 Objectives of the task force To advance and disseminate scientific knowledge on the effects of diet and food components on mental performance. To increase awareness of the importance of nutrition for brain function across the lifespan. 19

20 Task Force Members 2014 Dr Siobhan Mitchell Chair Nestlé CH Dr Caroline Saunders Vice-Chair PepsiCo International UK Prof. Keith Wesnes Co-Chair Northumbria University UK Dr Mélanie Charron Soremartec Italia Ferrero Group IT Ms Anja Holz Südzucker/BENEO Group DE Dr Sophie Kergoat Mars US Dr Hasan Mohajeri DSM CH Dr Lionel Noah Sanofi-Aventis R&D FR Dr María Ramírez Abbott Nutrition ES Dr John Sijben Danone NL Dr Berenike Stracke Schwabegroup DE Dr Barbara Winters Campbell Soup Company US Dr Pratima Rao Jasti ILSI Europe BE Mr Jeroen Schuermans ILSI Europe BE

21 Nutrition and Mental Performance Task Force Expert group on Nutrition for the Ageing Brain: Towards Evidence for an Optimal Diet Objectives of the expert group: no preventative dietary recommendations review the evidence supporting how nutrients, food and diet influence brain health 21

22 Recent publications Peer-reviewed publications Measuring and Validating the Subjective Effects of Food on Mood and Mental Performance (to be submitted to Nutrition Research Reviews) Cognitive Function: Criteria for Validation and Selection of Cognitive Tests for Investigating the Effects of Foods and Nutrients Brain Imaging and Human Nutrition: which Measures to Use in Intervention Studies? How to Assess Long-term Effects of N utrition on Brain Function? (proceedings) Nutrition and Cognition: Assessing Cognitive Abilities in Children and Young People The Influence of Children's Diet on their Cognition and Behavior 2008 Micronutrient Status, Cognition and Behavioral Problems in Childhood

23 Workshop on Nutrition for the Ageing Brain Towards Evidence for an Optimal Diet

24 Objectives of the workshop WHO: Improving public and professional understanding of dementia Is there evidence of an effect of diet or specific sets of nutrients or dietary factors on cognitive ageing? How to promote healthy cognitive ageing? If there is significant evidence, what are the effects of these nutrients or dietary factors on cognition? How do individual and environmental differences or other dietary components play a role in the effects of these nutrients? Are there age-specific dietary requirements? 24

25 Programme Overview Session 1: Introduction and Background Session 2: Mechanisms of Ageing and Neuroprotection via Nutrients Session 3: Can a Healthy Brain be Maintained and a Basic Balanced Diet What is the Role of Individual Variation? Session 4: Methodological Challenges Finding Solutions Session 5: Wrap to discuss Specific Nutrient Intake Levels and Cognitive Ability: Are there Optimal Levels for Preserving Cognition? Expected outcome: publication in a peer-review journal 25

26 Dissemination of the event 26

27 Have a fruitful workshop It is becoming widely accepted that lifestyle changes are the best protection against dementia, creating a massive opportunity for nutritional products Prof. Keith A. Wesnes - Northumbria University and optimal diets! 27

28 and enjoy your stay in Milan! The Last Supper, L. da Vinci (1498) 28

29

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