EVAN L. THACKER, PHD CURRICULUM VITAE MAY 2012

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1 CURRICULUM VITAE MAY 2012 CONTACT INFORMATION University of Alabama at Birmingham School of Public Health Phone: Department of Epidemiology Fax: Office: Ryals Public Health Building, Rm 220 Mail: rd Avenue South 1665 University Boulevard RPHB 220 Birmingham, AL Birmingham, AL EDUCATION Brigham Young University BS, cum laude Neuroscience 2003 Brigham Young University Certificate (15 credits) Gerontology 2003 Harvard School of Public Health SM Epidemiology 2005 University of Washington PhD Epidemiology 2011 Dissertation: Progression and complications of atrial fibrillation; Chair: Susan R. Heckbert ACADEMIC POSITIONS Position Department Institution Years Teaching assistant Neuroscience Center Brigham Young University Teaching assistant Epidemiology Harvard School of Public Health 2004 Teaching assistant Biostatistics Harvard School of Public Health Research assistant Nutrition Harvard School of Public Health Research assistant Epidemiology University of Washington Teaching assistant Epidemiology University of Washington Statistician Epidemiology University of Alabama at Birmingham 2011 present BIBLIOGRAPHY Peer-reviewed research articles (~300 citations in Scopus) 1. Thacker EL*, Mirzaei F*, Ascherio A. Infectious mononucleosis and risk for multiple sclerosis: A meta-analysis. Annals of Neurology Mar;59(3): PMID: *Joint first authors. 2. Thacker EL, Schneeweiss S. Initiation of acetylcholinesterase inhibitors and complications of chronic airways disorders in elderly patients. Drug Safety. 2006;29(11): PMID: Revised version of Harvard School of Public Health masters thesis. 3. Thacker EL, O Reilly EJ, Weisskopf MG, Chen H, Schwarzschild MA, McCullough ML, Calle EE, Thun MJ, Ascherio A. Temporal relationship between cigarette smoking and risk of Parkinson disease. Neurology Mar 6;68(10): PMID: PMCID: PMC

2 4. Thacker EL, Chen H, Patel AV, McCullough ML, Calle EE, Thun MJ, Schwarzschild MA, Ascherio A. Recreational physical activity and risk of Parkinson s disease. Movement Disorders Jan;23(1): PMID: PMCID: PMC Thacker EL, Ascherio A. Familial aggregation of Parkinson s disease: a meta-analysis. Movement Disorders Jun 15;23(8): PMID: Thacker EL, Wiggins KL, Rice KM, Longstreth WT Jr, Bis JC, Dublin S, Smith NL, Heckbert SR, Psaty BM. Short-term and long-term risk of incident ischemic stroke after transient ischemic attack. Stroke Feb;41(2): Epub 2009 Dec 3. PMID: PMCID: PMC Tobacco and Genetics Consortium. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nature Genetics May;42(5): Epub 2010 Apr 25. PMID: PMCID: PMC Ton TG, Jain S, Boudreau R, Thacker EL, Strotmeyer ES, Newman AB, Longstreth WT, Checkoway H. Post-hoc Parkinson s: identifying an uncommon disease in the Cardiovascular Health Study. Neuroepidemiology. 2010;35: Epub 2010 Sep 24. PMID: PMCID: PMC Garg RK, Glazer NL, Wiggins KL, Newton KM, Thacker EL, Smith NL, Siscovick DS, Psaty BM, Heckbert SR. Ascertainment of warfarin and aspirin use by medical record review compared with automated pharmacy data. Pharmacoepidemiology and Drug Safety. 2011;20: Epub 2010 Dec 23. PMID: Jain S, Ton TG, Boudreau RM, Yang M, Thacker EL, Studenski S, Longstreth WT Jr, Strotmeyer ES, Newman AB. The risk of Parkinson disease associated with urate in a community based cohort of older adults. Neuroepidemiology. 2011;36: PMID: Thacker EL, Psaty BM, McKnight B, Heckbert SR, Longstreth WT Jr, Mukamal KJ, Meigs JB, de Boer IH, Boyko EJ, Carnethon MR, Kizer JR, Tracy RP, Smith NL, Siscovick DS. Fasting and postglucose load measures of insulin resistance and risk of ischemic stroke in older adults. Stroke. 2011;42: Epub 2011 Oct 13. PMID: PMCID: PMC Ton TG, Jain S, Biggs ML, Thacker EL, Strotmeyer ES, Boudreau R, Newman AB, Longstreth WT Jr, Checkoway H. Markers of inflammation in prevalent and incident Parkinson s disease in the Cardiovascular Health Study. Parkinsonism and Related Disorders. 2012;18: Epub 2011 Nov 26. PMID: PMCID: PMC Britton KA, Mukamal KJ, Ix JH, Siscovick DS, Newman AB, de Boer IH, Thacker EL, Biggs ML, Gaziano JM, Djoussé L. Insulin resistance and incident peripheral artery disease in the Cardiovascular Health Study. Vascular Medicine. Epub 2012 Mar 8. PMID: Jain S, Ton TG, Perera S, Zheng Y, Thacker EL, Strotmeyer ES, Newman AB, Stein PK, Longstreth WT Jr. Cardiovascular physiology in pre-motor Parkinson disease: a neuroepidemiologic study. Movement Disorders. In press. 15. David SP*, Hamidovic A*, Chen GK*, Bergen AW, Wessel J, Kasberger JL, Brown WM, Petruzella S, Thacker EL, Kim Y, Nalls MA, Tranah GJ, Sung YJ, Ambrosone CB, Arnett D, 2

3 Bandera EV, Becker DM, Becker L, Berndt SI, Bernstein L, Blot WJ, Broeckel U, Buxbaum SG, Caporaso N, Casey G, Chanock SJ, Deming SL, Diver WR, Eaton CB, Evans DS, Evans MK, Fornage M, Franceschini N, Harris TB, Henderson BE, Hernandez DG, Hitsman B, Hu JJ, Hunt SC, Ingles SA, John EM, Kittles R, Kolb S, Kolonel LN, Le Marchand L, Liu Y, Lohman KK, McKnight B, Millikan RC, Murphy A, Neslund-Dudas C, Nyante S, Press M, Psaty BM, Rao DC, Redline S, Rodriguez-Gil JL, Rybicki BA, Signorello LB, Singleton AB, Smoller J, Snively B, Spring B, Stanford J, Strom SS, Swan GE, Taylor KD, Thun MJ, Wilson AF, Witte JS, Yamamura Y, Yanek LR, Yu K, Zheng W, Ziegler RG, Zonderman AB, Jorgenson E**, Haiman CA**, Furberg H**. Genome-wide meta-analyses of smoking behaviors in African Americans. Translational Psychiatry. In press. *Joint first authors. **Joint senior authors. Submitted research articles 1. Thacker EL, McKnight B, Psaty BM, Longstreth WT Jr, Sitlani CM, Dublin S, Arnold AM, Fitzpatrick AL, Gottesman RF, Heckbert SR. Atrial fibrillation and cognitive decline: a longitudinal cohort study. Submitted. 2. Thacker EL, McKnight B, Psaty BM, Longstreth WT Jr, Dublin S, Jensen PN, Newton KM, Smith NL, Siscovick DS, Heckbert SR. Higher body mass index as a risk factor for recurrence of atrial fibrillation and progression to permanent atrial fibrillation. Submitted. Research article in preparation 1. Thacker EL, Jensen PN, Psaty BM, McKnight B, Longstreth WT Jr, Dublin S, Newton KM, Smith NL, Siscovick DS, Heckbert SR. Use of statins and antihypertensive medications in relation to recurrence of atrial fibrillation and progression to permanent atrial fibrillation. Other scholarly publications 1. Thacker EL. The United States Long-Term Care Ombudsman Program: understanding the real-life circumstances underlying resident complaint data. Expert Review of Pharmacoeconomics and Outcomes Research Dec;6(6): PMID: Thacker E. Interaction between prestroke cognitive performance and incident stroke in predicting risk of dementia. Stroke Jul;39(7):e106; author reply e107. Epub 2008 May 22. PMID: Letter to the editor commenting on Reitz C, et al. Stroke Jan;39(1): CONFERENCE PRESENTATIONS AND ABSTRACTS Oral presentations 1. Thacker EL, O Reilly E, Weisskopf MG, Chen H, Schwarzschild MA, McCullough ML, Calle EE, Thun MJ, Ascherio A. Temporal relationship between cigarette smoking and risk of Parkinson s disease. Neurology. 2006;66(Suppl2):A382-A383. American Academy of Neurology 58 th Annual Meeting, San Diego, CA, April Thacker EL, Chen H, Patel AV, McCullough ML, Calle EE, Thun MJ, Schwarzschild MA, Ascherio A. Recreational physical activity and risk of Parkinson s disease. Neurology. 3

4 2007;68(Suppl1):A87. American Academy of Neurology 59 th Annual Meeting, Boston, MA, May Thacker EL, Wiggins KL, Longstreth WT Jr, Bis JC, Rice KM, Dublin S, Smith NL, Heckbert SR, Psaty BM. Short term and long term risk of first ischemic stroke after transient ischemic attack. NHLBI Cardiovascular Epidemiology, Biostatistics, and Prevention Trainee Session, Palm Harbor, FL, March Thacker EL, Siscovick DS, Psaty BM, Boyko EJ, McKnight B, Heckbert SR, Smith NL, Longstreth WT Jr, de Boer IH, Carnethon MR, Mukamal KJ, Kizer JR. Fasting insulin and incident ischemic stroke: the Cardiovascular Health Study. NHLBI Cardiovascular Epidemiology, Biostatistics, and Prevention Trainee Session, San Francisco, CA, March Jain S, Ton TG, Perera S, Zheng Y, Thacker EL, Studenski S, Longstreth WT Jr, Strotmeyer ES, Newman AB. Electrocardiographic abnormalities are associated with higher risk of Parkinson s disease in a community-based cohort of older adults. AAN Annual Meeting Abstracts. 2011:S URL: American Academy of Neurology 63rd Annual Meeting, Honolulu, HI, April Thacker EL, McKnight B, Psaty BM, Longstreth WT Jr, Sitlani CM, Arnold AM, Fitzpatrick AL, Dublin S, Gottesman RF, Heckbert SR. Atrial fibrillation and cognitive decline: the Cardiovascular Health Study. Circulation. 2012;125:A022. American Heart Association 52 nd Cardiovascular Disease Epidemiology and Prevention Conference, San Diego, CA, March Finalist for Jeremiah and Rose Stamler Research Award for New Investigators. 7. Vimalananda VG, Biggs ML, Rosenzweig JL, Carnethon MR, Meigs JB, Thacker EL, Siscovick DS, Mukamal KJ. Effects of sex and race on risk of congestive heart failure, coronary heart disease, and mortality in older adults with diabetes. American Diabetes Association 72 nd Scientific Sessions, Philadelphia, PA, June Poster presentations 1. Thacker EL, Schneeweiss S. Initiation of acetylcholinesterase inhibitors and acute exacerbation of chronic obstructive pulmonary disease. American Journal of Epidemiology. 2006;163(Suppl):S35. 2 nd North American Congress of Epidemiology, Seattle, WA, June Hindorff L, Thacker E, Rice K, Psaty B, Rosendaal F, Reitsma P, Heckbert S. CYP2C9 and VKORC1 genetic variation and bleeding events in patients with atrial fibrillation. Leducq International Network Against Thrombosis (LINAT) Annual Meeting, Oklahoma City, OK, May Thacker EL, Wiggins KL, Longstreth WT Jr, Bis JC, Rice KM, Dublin S, Smith NL, Heckbert SR, Psaty BM. Short term and long term risk of first ischemic stroke after transient ischemic attack. Circulation. 2009;119:E361. American Heart Association 49 th Cardiovascular Disease Epidemiology and Prevention Conference, Palm Harbor, FL, March Also presented at Leducq International Network Against Thrombosis (LINAT) Annual Meeting, Leuven, Belgium, May Ton TG, Jain S, Boudreau R, Thacker EL, Strotmeyer ES, Rhodes S, Newman A, Longstreth WT Jr, Checkoway H. Development of an algorithm to identify Parkinson s disease in the 4

5 Cardiovascular Health Study. Neurology. 2009;72(Suppl3):A451. American Academy of Neurology 61 st Annual Meeting, Seattle, WA, April Jain S, Ton TG, Boudreau RM, Thacker EL, Studenski S, Rhodes SL, Longstreth WT Jr., Strotmeyer ES, Newman AB. Urate and the risk of Parkinson disease in a community-based population in the United States (Cardiovascular Health Study). Movement Disorders. 2009;24(Suppl1):S th International Congress of Parkinson s Disease and Movement Disorders, Paris, France, June Thacker EL, Siscovick DS, Psaty BM, Boyko EJ, McKnight B, Heckbert SR, Smith NL, Longstreth WT Jr, de Boer IH, Carnethon MR, Mukamal KJ, Kizer JR. Fasting insulin and incident ischemic stroke: the Cardiovascular Health Study. AHA EPI/NPAM Joint Conference Abstracts. 2010:P325. URL: EPI_NPAM_FinalProg_ABSTRACTS.pdf. American Heart Association 50 th Cardiovascular Disease Epidemiology and Prevention Conference, San Francisco, CA, March Thacker EL, McKnight B, Psaty BM, Longstreth WT Jr, Dublin S, Jensen PN, Newton KM, Smith NL, Siscovick DS, Heckbert SR. Associations of demographic and medical history factors with recurrence of atrial fibrillation and progression to permanent atrial fibrillation. AHA EPI/NPAM Joint Conference Abstracts. 2011:MP59. URL: American Heart Association 51 st Cardiovascular Disease Epidemiology and Prevention Conference, Atlanta, GA, March Ton TG, Jain S, Thacker EL, Strotmeyer ES, Boudreau R, Newman AB, Longstreth WT, Checkoway H. Markers of inflammation in prevalent and incident Parkinson's disease in the Cardiovascular Health Study. AAN Annual Meeting Abstracts. 2011:P URL: American Academy of Neurology 63 rd Annual Meeting, Honolulu, HI, April Jensen PN, Thacker EL, Dublin S, Psaty BM, Heckbert SR. Racial differences in the incidence of and risk factors for atrial fibrillation in older adults: the Cardiovascular Health Study. Circulation. 2012;125:AP112. American Heart Association 52 nd Cardiovascular Disease Epidemiology and Prevention Conference, San Diego, CA, March Thacker EL, Jensen PN, Psaty BM, McKnight B, Longstreth WT Jr, Dublin S, Newton KM, Smith NL, Siscovick DS, Heckbert SR. Use of statins and antihypertensive medications in relation to recurrence of atrial fibrillation and progression to permanent atrial fibrillation. Circulation. 2012;125:AP118. American Heart Association 52 nd Cardiovascular Disease Epidemiology and Prevention Conference, San Diego, CA, March Invited seminar presentations 1. Fasting insulin and incident ischemic stroke: the Cardiovascular Health Study. Collaborative Health Studies Coordinating Center, University of Washington, Seattle, WA, March Measures of insulin resistance in the Cardiovascular Health Study. Cardiovascular Health Study Steering Committee meeting, Rosemont, IL, April

6 3. Atrial fibrillation and cognitive decline. Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, February Insulin resistance and ischemic stroke. Department of Pharmaceutical Outcomes and Policy, University of Florida, Gainesville, FL, April TEACHING HISTORY Formal courses Neurobiology (BYU undergraduate course) Role: Teaching assistant. Two semesters. Led review sessions with students and office hours for individual students; wrote, administered, and graded quizzes and tests. Instructor: Edwin D. Lephart. Biopsychology (BYU undergraduate course) 2003 Role: Curriculum developer. Developed PowerPoint lecture slides and reading list for a semesterlong course. Instructor: Edwin D. Lephart. Analytical aspects of clinical epidemiology (HSPH graduate course) 2004 Role: Teaching assistant. Three-week course. Assisted students with SAS programming questions during sessions with students led by instructor. Instructor: E. Francis Cook. Data management and programming in SAS (HSPH graduate course) Role: Teaching assistant. Two quarters. Assisted students with SAS programming questions during sessions with students led by instructor; held office hours for individual student help; graded homework assignments. Instructor: Elizabeth N. Allred. Epidemiologic methods I & II (UW graduate course) Role: Teaching assistant. Two quarters. Led weekly homework discussion sessions with students; held weekly office hours for individual student help; graded homework assignments. Instructors: Thomas D. Koepsell, Victoria L. Holt, Noel S. Weiss. Other teaching Statistics (BYU undergraduate course) 2003 Role: Peer tutor. One semester. Individual tutoring for two students. Molecular biology (BYU undergraduate course) 2003 Role: Peer tutor. One semester. Individual tutoring for one student. UW School of Public Health new student orientation case study 2009 Role: Discussion group leader. One session with 10 students. Topic: Heavy metals in fertilizer. Organizer: Carolyn Watts. Epidemiology doctoral dissertation seminar (UW graduate course) Role: Panelist. Three sessions with 15 students. Topics: starting your dissertation; taking the departmental general exam. Instructors: Scott Davis, Victoria L. Holt. 6

7 Principles of epidemiology (BYU undergraduate course) 2010 Role: Guest lecturer. One session with 60 students. Topic: Cohort studies and case-control studies: examples from neuroepidemiology and cardiovascular epidemiology. Instructor: Ray M. Merrill. Epidemiologic methods II (UW graduate course) 2011 Role: Guest lecturer. One session with 120 students. Topic: The tale of one cohort study: the Cardiovascular Health Study. Instructor: Victoria L. Holt. UW Epidemiology preliminary exam preparation group 2011 Role: Panelist. One session with 20 students. Topic: Taking the departmental preliminary exam. Organizer: Alastair Matheson. RESEARCH FUNDING HISTORY Research funding obtained as an undergraduate student Identifying barriers to patient recruitment in community RCTs 2003 $1,500 from BYU Office of Research and Creative Activities Role: Student PI. Faculty mentor: Ray M. Merrill. Research funding supporting me in staff positions NSAIDs, inflammation, and Parkinson s disease NINDS R01 NS048517, PI: Alberto Ascherio Role: Research assistant Genome-wide case-only study of antihypertensive drug-gene interactions NHLBI R01 HL085251, PI: Bruce M. Psaty Role: Research assistant Atrial fibrillation: incidence, risk factors, and genetics NHLBI R01 HL068986, PI: Susan R. Heckbert Role: Research assistant Etiology of geographic and racial differences in stroke NINDS U01 NS041588, PI: George Howard Role: Statistician 2011 present HONORS Eagle Scout, Boy Scouts of America 1993 Trustees Full Tuition Scholarship, Brigham Young University Phi Kappa Phi Honor Society, Brigham Young University 2002 Golden Key International Honour Society, Brigham Young University 2002 Predoctoral fellowship, University of Washington CVD epidemiology training program, NHLBI T32 HL007902, PI: David S. Siscovick Finalist, Jeremiah and Rose Stamler Research Award for New Investigators 2012 American Heart Association Epidemiology and Prevention Conference 7

8 PROFESSIONAL AND SERVICE ACTIVITIES Manuscript reviewer EVAN L. THACKER, PHD Basal Ganglia (1 review) BMC Medical Research Methodology (1 review) Cardiovascular Health Study Publications & Presentations Committee (4 reviews) Circulation (1 review) European Journal of Neurology (1 review) Expert Review of Anti-infective Therapy (1 review) Journal of Internal Medicine (1 review) Journal of the Neurological Sciences (1 review) Movement Disorders (1 review) Stroke (2 reviews) Professional organization membership American Heart Association 2008 present University service BYU Cougar Marching Band Rocky Mountain Festival committee 2002 UW Epidemiology Department seminar committee Community service Utah State Hospital geriatric unit volunteer, Provo, UT Salt Lake 2002 Olympics volunteer, Salt Lake City, UT Books and Basketball Program volunteer, Boston, MA 2003 Springwell Long-Term Care Ombudsman Program ombudsman, Boston, MA Boy Scouts of America scoutmaster, Birmingham, AL 2011 present 8