Presented by Joanna O Leary, MD Providence St. Vincent Medical Center Movement Disorder Department
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1 Presented by Joanna O Leary, MD Providence St. Vincent Medical Center Movement Disorder Department
2 Hyperkinetic movement disorders Increase in muscle movements causing involuntary motion Tremor Dystonia Myoclonus Chorea Tic
3 Questions to ask Where is your involuntary movement? When does the movement occur? How long have you had the movement? Was the onset abrupt? Do your arms feel uncoordinated? Do you have difficulty walking? Do you act out your dreams at night? Are you on psych or antiemetic meds?
4 Exam Rest Finger to nose Wing beat Spiral Handwriting Water pour Bradykinesia, rigidity and gait eval Neck range of motion Eye abnormalities
5 Parkinsonian tremor Rest tremor > posture > kinetic Usually asymmetric Pronation-supination tremor Distal joints involved primarily Often posturing of the limb Re-emergent tremor with posture
6 Parkinsonian tremor
7 Essential tremor Kinetic tremor Mildly asymmetric Intentional 50% Bringing spoon to mouth is challenging!! Worse in wing-beat position Kinetic > postural > rest Rest in 20%, late feature, only in arms Gait ataxia typically mild
8 Essential tremor Usually starts in arms Can progress to neck, voice and jaw over time Jaw tremor occurs with action, not rest Neck tremor starts yes-yes or no-no but can become multidirectional with time Neck tremor should resolve when patient is lying flat Neck tremor with minimal arm tremor is likely dystonic
9 Essential tremor
10 Dystonic tremor Dystonia - muscle contractions that cause sustained or intermittent torsion of a body part or repetitive motion Irregular, not rhythmic or oscillatory (rotational around a central plane) Often associated with posturing Head tremor is present in supine position Voice tremor has breaks, strangulation
11 Dystonic Tremor
12 Enhanced physiologic tremor Action tremor that most people have (e.g. with stress) Postural and kinetic Faster rate and lower amplitude than ET Not associated head tremor
13 Drug induced tremor Action tremors: Lithium, depakote, stimulants, prednisone, beta agonists, amiodarone Possible form of enhanced physiologic tremor Rest tremors: Some anti-emetics and anti-psychotics
14 Primary writing tremor Task specific tremor Only occur with writing Similar frequency to essential tremor Similar to writer s cramp without dystonic posturing
15 Orthostatic tremor 14 to 16 Hz tremor in legs Instability with standing Improves with walking or sitting Not always visible Evaluate with EMG
16 Cerebellar tremor Action tremor Worse with intention Slow at 3-4 Hz Overshoot Associated with other cerebellar features: E.g. dysarthria, ataxia
17 Holmes tremor Midbrain, pontine or thalamic lesion Usually unilateral Action > postural > rest Usually disabling Can occur months to years after onset of stroke Sometimes associated with dystonia or ataxia
18 Holmes tremor
19 Other tremors Psychogenic Abrupt onset, variable pattern, distactible, suggestible, entrainable Wilson s disease Fragile X Ataxia Peripheral neuropathy-related
20 Psychogenic Tremor
21 Peripheral neuropathy tremor
22 Other abnormal movements Myoclonus Brief jerk Can occur once or multiple times in a row Chorea Irregular flowing movement transitioning from one body part to another Tics Repeated movements or sounds that are repeatable, can be suppressed and are associated with an urge to produce the movement
23 Name the disorder - Case 1 CC: bilateral hand tremor 62 year old man Onset of tremor 2 years ago Difficulty eating, drinking and writing h/o lumbar radiculopathy, HTN Meds: GBP, HCTZ, metoprolol FHx of tremor (father)
24 Case 1
25 Name the Disorder - Case 2 CC: left hand tremor 67 yo RH man Onset of tremor x years ago, mild imbalance, mild hand slowness FHX: cardiac disease h/o DM, HTN Meds: propranolol, lovastatin, glipizide
26 Case 2
27 Name the disorder - Case 3 CC: head tremor 76 yo woman Head tremor x 10 years, no hand tremor, no improvement with primidone Meds: Sybicort inhaler h/o COPD FHx: HTN, DM
28 Case 3
29 Name the disorder - Case 4 CC: involuntary body movement 94 yo woman Onset 5 years ago. Symptoms occur in clusters for minutes to hours. Sometimes unilateral limb, sometimes entire body. Better with Valium Meds: tylenol 3, Norco, Effexor PMHx: Arthritis and breast ca
30 Case 4
31 Name the disorder - Case 5 CC: gait dysfunction 77 yo man Involuntary head movements, slowed arms and legs, shuffling gait and cognitive decline x 2 years Meds: ASA, metoprolol h/o CAD, aortic valve replacement FHx: Parkinson s mother and MGM
32 Case 5
33 Thank you to my patients for allowing me to tape them! References: Louis, E, Diagnosis and Management of Tremor. Continuum 2016;22(4):
Types of involuntary movements
Tremor Types of involuntary movements Dystonia Chorea Myoclonus Tics Tremor Rhythmic shaking of muscles that produces an oscillating movement Parkinsonian tremor Rest tremor > posture > kinetic Re-emergent
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