Towards personalised food and nutrition

Transcription

1 Towards personalised food and nutrition Prof. Dr. Koen September 20, 2017 Lernert & Sander Yumi 1

2 The science behind a meal Biology Technology Data Behaviour x Design Which one is sweetest? 2

3 Mood-enhancing food menu to create calmer in-flight experience Monarch Airlines Health = your biology + environment + lifestyle 3

4 Public health recommendations based on averages of population data Individuals differ in their response because of inherent variations in & complexity of individual genetic makeup & lifestyle & environment Tools emerge to translate these variations into personalized recommendations Based on great review van Ommen et al., Nutrition Reviews, Volume 75, 1 August 2017, Disease incidence ~ Change in dietetic habits when people migrate 4

5 4 cups a day and other mortality studies (N=20.000) N = study challenges conventional wisdom about carbs & fats 5

6 20/09/ Can your diet help fight disease? 6

7 Food as medicine ZOOM+Care Prime in Portland, Oregon, is taking a radical new approach to primary care. It incorporates many of the innovations already used in ZOOM+Care neighborhood clinics, including affordable transparent pricing, no-wait visits, and the ability to schedule visits via ZOOM s mobile app. What sets Prime clinics apart, however, is its emphasis on food and movement as a way to prevent and reverse chronic diseases. ZOOM+Care Prime, Portland, Oregon 7

8 Food as medicine Caelum Health wants to use software to improve people's health without prescribing them drugs. It's starting with irritable bowel syndrome, which affects 20 percent of Americans and leads to $55 billion worth of prescriptions. Caelum provides behavioral health treatments that it says are 3x more effective than prescription drugs, all on a mobile app platform. 8

9 Doctors pour drugs of which they know little, to cure diseases of which they know less, into patients of whom they know nothing Moliere, French author ( ) Moliere, French author ( ) 3 guardian angels (Gen)omics & biomerkers Sensors (wearables,..) Internet of Things 9

10 Your personal genome - DNA code The era of Personal genome analysers Oxford Nanopore 10

11 The 1000$ genome 11

12 Personalised nutrition based on DNA polymorphisms Habit (Neuro) biology of personalised food 12

13 Resto menu based on your DNA The sweet tooth gene 13

14 Obese people lack cells with satiety hormones Grasping walnuts Walnuts activate portion of the brain involved in cognitive control, making it easier for you to stop overeating 14

15 Eating at 'wrong time' affects body weight, circadian rhythms 15

16 From: Systems biology of personalized nutrition Nutr Rev. 2017;75(8): doi: /nutrit/nux029 Genes VERSUS diet -> Genes AND diet Disease Disease Disease Genes Diet Genes Diet Diet Genes 16

17 The epigenetic code 20/09/2017 Calorie restriction -> lengthened lifespan by slowing down epigenetic drift 17

18 Diet & gut microbiome influence epigenetic modulation No guts no glory: Harvesting the microbiome of athletes 18

19 Gut bacteria trigger gene complex protecting against autoimmune disease (T1 diabetes, ) 19

20 Quantified Self generation Step detection 2. Heart Pulse Nike Fuelband FitBit Force 3. Heart rate variability 4. Blood pressure 5. Blood oxygenation 6. Body temperature 7. Sleep Actionable insights Hapifork 20

21 Track calories simply photographing your food 21

22 Tracking diet with chew-monitoring necklace or speech Track Your Diet with a Chew-Monitoring Necklace Autodietary, Univ Buffalo Wearable food nutrition feedback system Microsoft 22

23 Unhealthy cravings curbed by smartphone treatment project ICare Artificial intelligence to turn images of food into recipes 23

24 Ingredient scanners marching on 24

25 Portable food scanners SCiO Bosch X-Spect Allergen detector could fit in your pocket Harvard Medical School 25

26 Synthetic biology powered food Aranex biotech From: Systems biology of personalized nutrition Nutr Rev. 2017;75(8): doi: /nutrit/nux029 26

27 1st artificial pancreas approved, T1D Medtronic, Sugar.IQ, powered by IBM Watson 27

28 cure.fit 28

29 If nutrition labels looked like this 29

30 Mac donals wearables allergy Mirrored tableware tricks brain to change eating habits Studio Playfool 30

31 Lifestyle options from restrictions to opportunities HealthSlate 31

32 Jobs of the future Communication with (food) coaches HealthSlate 32

33 Soon 1st Personalised food prevention App 1st mobile Health App reimbursement (2013) Sickcare -> Healthcare Precise medicine to Personalised Prevention Omics Biomarkers Actions / Behaviours Sensors Internet of Things BIG Data Devices / Robots Artificial Intelligence Machine Learning Baymax, Big Hero 6 33

34 The Ikea Recipe Series is the irresistible cookbook you never knew was possible. The Ikea Recipe Series How can we help you? Eye-opening, inspiring Keynotes Self-learning Newsletter Unknown unknowns Connectors unlocking data silo s Prof. Dr. Koen Kas Healthskouts.com 34