Labs- automated ELR Labs reporting manually Health care providers. immediate within 7 days. immediate within 7 days. immediate within 7 days.

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1 Immediate Notification: Douglas Co. (402) (after hrs ) Lancaster Co (402) (or page ) All Other Counties - Call Local County Health Dept AND State Epi at Nebraska Public Health Laboratory 24/7 pager Acinetobacter spp. Acquired Immunodeficiency Syndrome (AIDS), as described in 173 NAC C2 Adenovirus infection (conjunctivitis, respiratory) Amebae-associated infection (Acanthamoeba spp, Entamoeba histolytica, and Naegleria fowleri ) Anthra (Bacillus anthracis^) * Arboviral infections (including, but not limited to, West Nile virus, St. Louis encephalitis virus, Western equine encephalitis virus, and Dengue virus) Babesiosis (Babesia species) Botulism (Clostridium botulinum )* Brucellosis (Brucella abortus^, B. melitensis^, and B. suis^)* Campylobacteriosis (Campylobacter species) Do not forward to NPHL for banking or subtyping unless requested. Carbon monoide poisoning (Use break point for non-smokers) Chancroid (Haemophilus ducreyi ) ± Chlamydia trachomatis infections (nonspecific urethritis, cervicitis, salpingitis, neonatal conjunctivitis, pneumonia) ± Cholera (Vibrio cholerae ^) Clostridium difficile Coccidiodomycosis (Coccidioides immitis/posadasii ^)* 1

2 Creutzfeldt-Jakob Disease [transmissible spongiform encephalopathy ( protein from CSF or any laboratory analysis of brain tissue suggestive of CJD)] Cryptosporidiosis (Cryptosporidium parvum ) Cyclosporiasis (Cyclospora cayetanensis ) Dengue virus infection Diphtheria (Corynebacterium diphtheriae ) Eastern equine encephalitis (EEE virus^)* Ehrlichiosis, human granulocytic (Anaplasma phagocytophilum ) Ehrlichiosis, human monocytic (Ehrlichia chaffeenis ) Encephalitis (caused by viral agents) Enterocococcus spp., all isolates Enterococcus spp., vancomycin-resistant (MIC>32 m g/ml and/or resistant by disk diffusion) and intermediate (MIC=8-16 m g/ml) Escherichia coli gastroenteritis (E. coli O157-H7^ and other Shigatoin-postive E. coli from gastrointestinal infection^) Food-poisoning, outbreak-associated Giardiasis (Giardia lamblia ) Glanders [Burkholderia (Pseudomonas ) mallei^ ]* Gonorrhea (Neisseria gonorrhoeae ): venereal infection and ophthalmia neonatorum ± Haemophilus influenzae^ infection (invasive disease only) Hansen's Disease [Leprosy (Mycobacterium leprae )] Hantavirus pulmonary syndrome (Sin Nombre virus) Hemolytic uremic syndrome (post-diarrheal illness) Hepatitis A (IgM antibody-positive or clinically diagnosed during an outbreak) Hepatitis B infection (positive surface antigen tests and all IgM core antibody tests, both positive and negative) ± 2

3 Hepatitis C (all positive screening tests [e.g. EIA, ELISA, etc] to include signal-to-cutoff ratio [S:CO] are reportable; all confirmatory tests [e.g., RIBA, NAT tests such as PCR for qualitative, quantitative and genotype testing] are reportable regardless of result [i.e., both positive and negatives tests]) Hepatitis D and E Herpes simple, primary genital infection ± Histoplasmosis (Histoplasma capsulatum ) Human immunodeficiency virus infection, as described in 173 NAC C2, Type 1 and suspected cases of HIV Type 2 ± Influenza (Antigen or PCR positive or culture confirmed) Influenza deaths, pediatric (<18 years of age) Influenza due to novel or pandemic strains (includes highly pathogenic avian influenza virus^*) Influenza, all tests Influenza, rapid tests summary report only (laboratories only) Kawasaki disease (mucocutaneous lymph node syndrome) Klebsiella spp. Lead poisoning (all analytical values for blood lead analysis shall be reported) Legionellosis (Legionella species) Leptospirosis (Leptospira interrogans ) Listeriosis (Listeria monocytogenes^) Lyme disease (Borrelia burgdorferi ) Lymphocytic choriomeningitis virus infection Lymphogranuloma venereum (LGV [Chlamydia trachomatis ]) ± Marburg virus* Malaria (Plasmodium species) Measles (Rubeola) Melioidosis [Burkholderia (Pseudomonas) pseudomallei]* ^ 3

4 Meningitis (Haemophilus influenzae ^ or Neisseria meningitidis ^) Meningitis, including viral, bacterial, and fungal (all such cases must be reported within seven ecept those caused by Haemophilus influenzae and Neisseria meningitidis, which must be reported ly) Meningococcal disease, invasive (Neisseria meningitidis ^) Methemoglobinemia/nitrate poisoning (methemoglobin greater than 5% of total hemoglobin) Monkeypo virus infection * Mumps Mycobacterium spp, invasive infection (including M. tuberculosis comple and atypical Mycobacterium spp. associated with invasive disease) Send only MTB comple to NPHL^ Necrotizing fasciitis Norovirus (laboratories only) Pertussis [whooping cough] (Bordetella pertussis^) Plague (Yersinia pestis ^)* Poisoning or illness due to eposure to chemicals (agricultural: herbicides, pesticides, and fertilizers), industrial chemicals, mercury, radiologic eposures Poliomyelitis paralytic Psittacosis (Chlamydophilia psittaci ) Q fever (Coiella burnetii^)* Rabies, (human and animal cases and suspects) Respiratory syncytial virus infection, all tests (laboratories only) Retrovirus infections (other than HIV) Rheumatic fever, acute (cases meeting the Jones criteria only) Ricin poisoning* Rift Valley Fever* Rocky Mountain Spotted Fever (Rickettsia rickettsii^ )* 4

5 Rotavirus (all positive and negative tests) Rubella and congenital rubella syndrome Salmonellosis, including typhoid fever (Salmonella serogroups^) Severe Acute Respiratory Syndrome [SARS] (SARS-associated coronavirus) Shiga toin positive gastroenteritis (enterhemorrhagic E coli and other shiga toin-producing bacteria^) Shigellosis (Shigella species^) Smallpo^* Staphylococcal enterotoin B intoication* Staphylococcus aureus (all isolates) Staphylococcus aureus, methicillin-resistant (MIC>=4mg/mL and/or resistant by disk diffusion) Staphylococcus aureus, vancomycin-intermediate/resistant (MIC>=4mg/mL) Streptococcal disease (all invasive disease caused by Groups A and B streptococci) Streptococcus pneumoniae, penicillin-intermediate (MIC= mg/ml) and penicillin-resistant (MIC>=2.0 mg/ml) Streptococcus pneumoniae (Sterile Body Sites) Syphilis (Treponema pallidum ) RPR and FTA ± Syphilis, congenital Tetanus (Clostridium tetani ) Tick-borne encephalitis, virus complees (Central European Tickborne encephalitis virus, Far Eastern Tick-borne encephalitis virus, Kyasanur Forest disease virus. Omsk Hemorrhagic Fever virus, Russian Spring and Summer encephalitis virus)* Toic Shock Syndrome Tooplasmosis, acute (Tooplasma gondii ) 5

6 Transmissible spongiform encephalopathies Trichinosis (Trichinella spiralis ) Tuberculosis (to include all M. tuberculosis comple organisms^ [for genotyping]; culture or nucleic acid test positive or positive histological evidence indicative of tuberculosis infection) Tularemia (Francisella tularensis^ )* Typhus Fever, louse-borne (Rickettsia prowazekii^)* and flea-borne/ endemic murine (Rickettsia typhi) Varicella primary infections (chicken po) Varicella mortality (all ages) Venezuelan equine encephalitis* Viral hemorrhagic fever (including but not limited to Ebola virus, Marburg virus, and Lassa fever virus)* Yellow Fever Yersiniosis (Yersinia species not Y. pestis) * Potential agents of bioterrorism (Designated as select agents by CDC) Immediate Notification for automated ELR Labs - Required to call by telephone to a live public health surveillance official within 24 hours of detection Immediate Notification for Labs reporting manually - Required to call by telephone to live public health surveillance official within 24 hours of detection ^ Laboratories where the specimen originated, must submit the isolate and/or specimen to the Nebraska Public Health Lab as specified in Title 173 NAC Laboratories performing electronic lab reporting as specified in 173 NAC C must report any antibiotic susceptibility test results ± STD in accordance with Neb. Rev. Stat