C-type: For each numbered item or question, indicate whether it is associated
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1 C-type: For each numbered item or question, indicate whether it is associated with: (A) A only (B) B only (C) Both A and B (D) Neither A nor B ( ) 1. About neuroleptic malignant syndrome and serotonin syndrome, which statement(s) is (are) TRUE? A. Both have autonomic dysfunction B. Myoclonus is prominent in serotonin syndrome. ( ) 2. Treatment side effect of Parkinson disease A. D2/D3 ratio decrease may cause impulse control problems B. Pergolide may cause restrictive fibrotic cardiac valvulopathy 解答 :C ( ) 3. Deep brain stimulation in idiopathic Parkinson disease can effectively reduce: A. Postural instability B. Parkinson disease dementia and psychosis 解答 :D ( ) 4. About the frontotemporal dementia (FTD) 1
2 A. Patients with bvftd have problems sustaining attention and develop personality changes B. PPA (Primary progressive aphasia) is a fluent aphasia 解答 : A ( ) 5. About the clinical features of dementia with lewy body (DLB) A. The cholinergic deficit may be more severe than in Alzheimer disease B. Cortical LB counts correlate with clinical severity ( ) 6. Internuclear ophthalmoplegia (INO) is characterized by: A. paresis of adduction of one eye B. horizontal nystagmus in the ipsilateral eye when it is abducted 解答 : A ( ) 7. Which drug(s) may cause reversible posterior leukoencephalopathy: A. Methotrexate B. Erythropoetin 解答 :(C) ( ) 8. Potassium channel is associated with the following disorder (s): A. Myotonia congenita B. Episodic ataxia type 1 (EA-1) 解答 : B ( ) 9. Long-term colchicine use for suppression of gout in patients with mild renal 2
3 insufficiency may cause A. distal axonal neuropathy B. proximal weakness with elevated serum CK level ( ) 10. About Adie s tonic pupil, which one(s) of the following statements is (are) TRUE? A. Degeneration of the ciliary ganglia and the postganglionic parasympathetic fibers B. Adie s pupil responds better to light than it does to near (accommodation) 解答 : A ( ) 11. Which of the following condition(s) can cause central pontine myelinolysis? A. Rapid correction of hyponatremia B. Alcoholic binge drinkers ( ) 12. Which description about familial amyloid polyneuropathy is TRUE? A. dysautonomia is frequent B. usually childhood onset ( ) 13. About serological antibody markers in Güillain-Barré syndrome (GBS) and its variants, which is TRUE? A. Anti-GM1 and anti-gd1a antibodies in axonal GBS B. Anti-GQ1b antibody in Miller Fisher syndrome 解答 : (C) ( ) 14. Which of the following response(s) in the EEG is (are) considered normal? 3
4 A. Occipital driving during photic stimulation B. Build-up during hyperventilation 解答 : C ( ) 15. Which of the following diseases can present cerebral infarction? A. Fabry disease B. Neurofibromatosis type I ( ) 16. Genes associated with intracerebral hemorrhage A. Amyloid precursor protein gene B. Cystatin C gene ( ) 17. Which of the following statement(s) is (are) TRUE? A. Moyamoya disease, also known as primary moyamoya, is thought to be autosomal dominant with incomplete penetrance. B. Secondary moyamoya is less common, accounting for about 10% of cases. 解答 :A ( ) 18. Which of the following is TRUE about primary stabbing headache? A. a brief and sharp pain that occurs without warning; also called ice-pick headache B. more common in patients with migraine and cluster headaches 4
5 ( ) 19. About posttraumatic epilepsy A. Immediate seizures are the risks for both early seizure and late seizure B. For severe head trauma patient, the phenytoin is used for the first week after injury to minimize complication from seizure occurring during acute management. 解答 :(B) ( ) 20. Which drug(s) may increase the half-life of lamotrigine? A. Valproate B. Phenytoin 解答 :(A) ( ) 21. Which of the following statement(s) about dural sinus thrombosis is(are) TRUE? A. Anterior cavernous sinus thrombosis present marked chemosis and proptosis. Disordered function of cranial nerves III, IV, VI, and the ophthalmic division of V may follow. B. Posterior cavernous sinus thrombosis may cause palsies of cranial nerves VI, IX, X and XI with proptosis. 解答 : A ( ) 22. Which hereditary disease may be associated with diabetes mellitus and hearing loss? A. MELAS B. Friedrich ataxia 解答 :(C) 5
6 ( ) 23. Which of the following pathogen(s) can cause petechial rash? A. Echovirus 9 B. Meningococcus 6
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