HERPESVIRUS DISEASES OF CATTLE, HORSES, AND PIGS

Transcription

1 HERPESVIRUS DISEASES OF CATTLE, HORSES, AND PIGS

2 Yechiel Becker, Series Editor Julia Hadar, Managing Editor DEVELOPMENTS IN VETERINARY VIROLOGY Payne, L.N. (ed.) Marek's Disease (1985) Burny, A. and Mammerickx, M. (eds.) Enzootic Bovine Leukosis and Bovine Leukemia Virus (1987) Becker, Y. (ed.) African Swine Fever (1987) De Boer, G.F. (ed.) Avian Leukosis (1987) Liess, B. (ed.) Classical Swine Fever and Related Viral Infections (1988) Darai, G. (ed.) Virus Diseases in Laboratory and Captive Animals (1988) Campbell, 1.B. and Charlton, K.M. (eds.) Rabies (1988) Alexander, D.l. (ed.) Newcastle Disease (1988) Wittmann, G. (ed.) Herpesvirus Diseases of Cattle, Horses, and Pigs (1989) DEVELOPMENTS IN MOLECULAR VIROLOGY Becker, Y. (ed.) Herpesvirus DNA (1981) Becker, Y. (ed.) Replication of Viral and Cellular Genomes (1983) Becker, Y. (ed.) Antiviral Drugs and Interferon: The Molecular Basis of Their Activity (1983) Kohn, A. and Fuchs, P. (eds.) Mechanisms of Viral Pathogenesis from Gene to Pathogen (1983) Becker, Y. (ed.) Recombinant DNA Research and Viruses. Cloning and Expression of Viral Genes (1985) Feitelson, M. Molecular Components of Hepatitis B Virus (1985) Becker, Y. (ed.) Viral Messenger RNA: Transcription, Processing, Splicing and Molecular Structure (1985) Doerfler, W. (ed.) Adenovirus DNA: The Viral Genome and Its Expression (1986) Aloni, Y. (ed.) Molecular Aspects oj Papovaviruses (1987) DEVELOPMENTS IN MEDICAL VIROLOGY Levine, P.H. (ed.) Epstein-Barr Virus and Associated Diseases (1985) Becker, Y. (ed.) Virus Infections and Diabetes Mellitus (1987) De Clercq, E. (ed.) Clinical Use of Antiviral Drugs (1988) Revel, M. (ed.) Clinical Aspects of Interferons (1988) Gilden, D. H. and Lipton, H. L. (eds.) Clinical and Molecular Aspects of Neurotropic Virus Infection (1989)

3 HERPESVIRUS DISEASES OF CATTLE, HORSES, AND PIGS edited by O. Wittmann Federal Research Centre for Virus Diseases of Animals Tubingen, Federal Republic of Germany Kluwer Academic Publishers Boston/Dordrecht/London

4 Distrlbuton for North America: Kluwer Academic Publishers 101 Philip Drive Assinippi Park Norwell, Massachusetts 02061, USA Distrlbuton for the UK and Ireland: Kluwer Academic Publishers Falcon House, Queen Square Lancaster LAI IRN, UNITED KINGDOM Distrlbuton for all otber countries: Kluwer Academic Publishers Group Distribution Centre Post Office Box AH Dordrecht, THE NETHERLANDS The figure on the cover is from H. W. Reid and D. Buxter, "Malignant catarrhal fever and the gammaherpesvirinae of bovidae... The figure appears on page 128 of this book. Ubrary of Congress Cataloglng.ln.PubUcatlon Data Herpesvirus diseases of cattle, horses, and pigs I edited by G. Wittmann. p. cm. - (Developments in veterinary virology; DVV9) Includes bibliographies and index. ISBN-13: e-isbn-13: DOl: / I. Herpesvirus diseases in animals. I. Wittmann, G. (Giinther), II. Series. [DNLM: I. Cattle Diseases. 2. Herpesviridae. 3. Herpesvirus Infections-veterinary. 4. Horse Diseases. 5. Swine Diseases. WI DE998V DVV9 I SF 961 H563) SF809.H47H '6952-dcI9 DNLM/DLC for Library of Congress CIP Copyright 1989 by Kluwer Academic Publishers Softcover reprint of the hardcover 1st edition 1989 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher, Kluwer Academic Publishers, 101 Philip Drive, Assinippi Park, Norwell, Massachusetts

5 CONTENTS CONTRIBUTORS PREFACE 1. Infectious Bovine Rhinotracheitis/Vulvovaginitis (BHV 1) R. Wyler, M. Engels, and M. Schwyzer 2. Bovine Herpesvirus 2 Infection F.M.M. Scott 3. Bovine Herpesvirus-4 (BHV 4) Infections of Cattle E. Thiry, M. Bublot, J. Dubuisson, and P. -P. Pastoret 4. Malignant Catarrhal Fever and the Gammaherpesvirinae of Bovidae H. W. Reid and D. Buxton 5. Aujeszky's Disease in Ruminants G. Wittmann 6. Herpesviral Diseases of the Horse J.T. Bryans and G.P. Allen 7. Aujeszky's Disease (Pseudorabies) in Pigs G. Wittmann and H. -J. Rziha 8. Porcine Cytomegalovirus V. Ohlinger INDEX vii ix

6 LIST OF CONTRIBUTORS ALLEN, G.P. Department of Veterinary Science College of Agriculture University of Kentucky Lexington, KY USA BRYANS, J.T. Departmen t of Veterinary Science College of Agriculture University of Kentucky Lexington, KY USA BUBLOT, M. Department of Virology Inununology Faculty of Veterinary Medicine University of Liege B-1070 Brussels Belgium BUXTON, D. Moredun Research Institute 408 Gilmerton Road Edinburgh UK DUBUISSON, J. Department of Virology Inununology Faculty of Veterinary Medicine University of Liege B-1070 Brussels Belgium ENGELS, M. Institute of Virology University of ZUrich Winterthurerstrasse 266a CH-8057 ZUrich Switzerland OHLINGER, V. Federal Research Centre for Virus Diseases of Animals P.O. Box 1149 D-74OO TUbingen Federal Republic of Germany PASTORET, P.-P. Department of Virology Inununology Faculty of Veterinary Medicine University of Liege B-1070 Brussels Belgium REID, H.W. Moredun Research Institute 408 Gilmerton Road Edinburgh UK RZIHA, H. -J Federal Research Centre for Virus Diseases of Animals P.O. Box 1149 D-7400 TUbingen Federal Republic of Germany SCHWYZER, M. Institute of Virology University of ZUrich Winterthurerstrasse 266a CH-8057 ZUrich Switzerland SCOTT, F.M.M. Moredun Research Institute 408 Gilmerton Road Edinburgh UK THIRY, E. Department of Virology Inununology Faculty of Veterinary Medicine University of Liege B-1070 Brussels Belgium

7 viii WITTMANN, G. Federal Research Centre for Virus Diseases of Animals P.O. Box TUbingen WYLER, R. Institute of Virology University of ZUrich Winterthurerstrasse 266a CH-8057 ZUrich Switzerland

8 PREFACE '!he present volune Herpesvirus Diseases of cattle, Horses and pigs in the series "Developnents in Veterinal:y Virology" gives a review on herpesvirus infections in (a) cattle by bovine herpesvirus I (lev-i), lev-2 and lev-4, alcelaphine herpesvirus I (malignant catanbal. fever) and Aujeszky"s disease virus, (b) horses by equine herpesvirus I (EHV-1), EHV-2 and EHV-3 and (c) pigs by Aujeszky's disease virus and porcine cytomegalovirus. Some of these viruses also infect small ruminants, therefore sheep and goats are included in this review as far as they are concemed. The different chapters include the latest knowledge on the viruses and the resulting diseases. Bearing in m:irrl the rapid development of oolecular biology and genetechnology in the last years a comprehensive survey on the oolecular aspects of the viruses and genetically engineered vaccines is presented, as far as data have been available. However, the other fields have not been neglected. large space is given to the description of clinical synptams, pathology, pathogenesis, latent infection, physical, chemical and biological characteristics of the viruses, hmnoral and cell-mediated imnunity, vaccines and vaccination, epizootiology, control, eradication, economics considerations and future aspects. Therefore, the book does not only apply to scientists working on herpesviruses but also to the veterinal:y service involved in control of the diseases and to practising veterinarians, who want to inprove their knowledge. All of them will fini objects of their interest, and 1008 references facilitate the search for oore detailed infonnation.

9 x I wish to thank the authors of the different chapters ani all the other persons who helped to finish the book. G. wittmaim. TUbin;Jen

10 HERPESVIRUS DISEASES OF CATTLE, HORSES, AND PIGS