OptumRx generic pipeline forecast

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1 OptumRx generic pipeline forecast 2017 DAYTRANA Noven Therapeutics methylphenidate Transdermal patch All 2017 NORVIR AbbVie ritonavir Capsule; tablet All 2017 PROVENTIL HFA Merck albuterol sulfate Inhalation All 2017 TRAVATAN Z Alcon/Novartis travoprost Ophthalmic All 2017 ZAVESCA Actelion miglustat Capsule All 2017 SPRIX Egalet ketorolac Intranasal All 2017 TRACLEER Actelion bosentan Tablet All 2017 BETIMOL Oak/Akorn timolol Ophthalmic All H SYPRINE Valeant trientine Capsule All H BYETTA AstraZeneca exenatide Subcutaneous All H FENTORA Teva fentanyl Tablet, buccal All H ADCIRCA Eli Lilly/United Therapeutics tadalafil Tablet All INVANZ Merck ertapenem Intravenous All MENOSTAR Bayer estradiol Transdermal patch All GANIRELIX Organon/Merck ganirelix acetate Injection All KALETRA AbbVie lopinavir/ritonavir Tablet All REYATAZ Bristol-Myers Squibb atazanavir Capsule All SUSTIVA Bristol-Myers Squibb efavirenz Tablet 600 mg VIAGRA Pfizer sildenafil Tablet All VIREAD Gilead tenofovir disoproxil fumarate Tablet 300 mg ADVAIR DISKUS GlaxoSmithKline fluticasone/salmeterol xinafoate Inhalation All 2018 MINIVELLE Noven estradiol Transdermal patch All 2018 PROAIR HFA Teva albuterol sulfate Inhalation All 2018 SAMSCA Otsuka tolvaptan Tablet All 2018 TRISENOX Cephalon/Teva arsenic trioxide Intravenous All 2018 optum.com/optumrx 1

2 ZYTIGA Janssen abiraterone Tablet All 2018 THALOMID Celgene thalidomide Capsule All 2018 EPOGEN epoetin alfa Amgen PROCRIT epoetin alfa Janssen SUPRENZA Citius/Akrimax phentermine Subcutaneous; intravenous Subcutaneous; intravenous Tablet, orally disintegrating All All All H ISTALOL Valeant timolol Ophthalmic All H ZORTRESS Novartis everolimus Tablet All Q RITUXAN Genentech/Roche/Biogen Idec FORFIVO XL IntelGenX/Edgemont bupropion rituxumab Intravenous All Q All ISTODAX Celgene romidepsin Intravenous All MAKENA Lumara Health/Amag Pharmaceuticals hydroxyprogesterone caproate Intramuscular All TREXIMET Pernix naproxen/sumatriptan succinate Tablet All SENSIPAR Amgen cinacalcet Tablet All NUVARING Merck etonogestrel/ethinyl estradiol Vaginal ring All INVEGA TRINZA Janssen paliperidone palmitate Intramuscular, extended-release All ABSTRAL Sentynl fentanyl citrate Tablet, sublingual All EMSAM Somerset/Mylan selegiline Transdermal patch All REMODULIN United Therapeutics treprostinil Injection All LEVITRA GSK/Bayer vardenafil Tablet All Q LETAIRIS Gilead Sciences ambrisentan Tablet All Q ACANYA Valeant clindamycin/benzoyl peroxide Gel All AMPYRA Acorda dalfampridine All XENICAL Roche orlistat Capsule All MOVIPREP Salix/Valeant PEG-3350/sodium sulfate/sodium chloride/potassium chloride/sodium ascorbate/ascorbic acid Oral solution All TOLAK Hill Dermaceuticals fluorouracil Cream All CIALIS Eli Lilly tadalafil Tablet All ALOXI Helsinn/Eisai palonosetron Intravenous All PYLERA Allergan/Aptalis bismuth subcitrate potassium/metronidazole/tetracycline Capsule All Q optum.com/optumrx 2

3 RAPAFLO Allergan silodosin Capsule All Q ENBREL Amgen etanercept Subcutaneous All Q NEULASTA Amgen pegfilgrastim Subcutaneous All Q STAXYN Bayer vardenafil Tablet, orally disintegrating All FINACEA Bayer azelaic acid Gel All PULMICORT Flexhaler AstraZeneca budesonide Inhalation All ASTAGRAF XL Astellas tacrolimus BASAGLAR Eli Lilly/Boehringer Ingelheim Capsule, extendedrelease All insulin glargine recombinant Subcutaneous All CANASA Forest/Allergan mesalamine Rectal suppository All ELIDEL Valeant pimecrolimus Cream All XOLAIR Roche/Genentech omalizumab Intravenous All s CUVPOSA Merz glycopyrrolate Oral solution All 2019 ROZEREM Takeda ramelteon Tablet All 2019 TARCEVA OSI Pharma/Genentech/Pfizer erlotinib Tablet All 2019 OMNARIS Sunovion/Takeda ciclesonide Intranasal All H HERCEPTIN Genentech/Roche trastuzumab Intravenous All Q BEPREVE Bausch & Lomb/Valeant bepotastine Ophthalmic All LATUDA Sunovion lurasidone Tablet All TEKTURNA Novartis aliskiren Tablet All ZYCLARA Medicis imiquimod Cream All ADVATE Baxalta antihemophilic factor (recombinant), plasma/albumin-free method Intravenous All GILENYA Novartis fingolimod Capsule All KORLYM Corcept mifepristone Tablet All RANEXA Gilead ranolazine All AZASITE Akorn azithromycin Ophthalmic All EMEND Merck fosaprepitant dimeglumine Intravenous All FASLODEX AstraZeneca fulvestrant Intramuscular All ACTEMRA Roche/Chugai tocilizumab Intravenous; subcutaneous All BENEFIX Pfizer coagulation factor IX (recombinant) Intravenous All optum.com/optumrx 3

4 CETROTIDE EMD Serono cetrorelix Subcutaneous All EXJADE Novartis deferasirox Tablet All FLECTOR Pfizer diclofenac epolamine Transdermal patch All VESICARE Astellas solifenacin Tablet All EPANED KIT Silvergate enalapril Oral solution All DYLOJECT Hospira/Pfizer/ Javelin diclofenac Intravenous All LEVEMIR Novo Nordisk insulin detemir recombinant Subcutaneous All LYRICA Pfizer pregabalin Capsule; solution All RESCRIPTOR ViiV Healthcare delavirdine Tablet All FIRAZYR Shire icatibant acetate Subcutaneous All AVASTIN Genentech bevacizumab Intravenous All STRIANT Auxilium testosterone Tablet All TORISEL Pfizer temsirolimus Injection All FORTEO Eli Lilly teriparatide Injection All EDLUAR Meda/Orexo zolpidem Tablet, sublingual All YOSPRALA Aralez aspirin/omeprazole Tablet, delayedrelease All MYOBLOC US WorldMeds botulinum toxin type B Intramuscular All ORENCIA Bristol-Myers Squibb abatacept Intravenous; subcutaneous All CYSTARAN Sigma Tau cysteamine hydrochloride Ophthalmic All JADENU Novartis deferasirox Tablet All VERMOX Janssen mebendazole Tablet, chewable All OSMOPREP Salix sodium phosphate/sodium phosphate Tablet All TREANDA Cephalon; Teva bendamustine hydrochloride Intravenous All AMELUZ Biofrontera aminolevulinic acid Gel All DUREZOL Alcon/Novartis difluprednate Ophthalmic All APTENSIO XR Rhodes methylphenidate + = may launch during the stated date or later Capsule, extendedrelease All optum.com/optumrx 4

5 optum.com/optumrx The information contained herein is compiled from various sources and is provided for informational purposes only. Due to factors beyond the control of OptumRx, information related to prospective drug launches is subject to change without notice. This information should not be solely relied upon for formulary decision-making purposes. OptumRx specializes in the delivery, clinical management and affordability of prescription medications and consumer health products. We are an Optum company a leading provider of integrated health services. Learn more at optum.com. All Optum trademarks and logos are owned by Optum, Inc. All other brand or product names are trademarks or registered marks of their respective owners. This document contains information that is considered proprietary to OptumRx and should not be reproduced without the express written consent of OptumRx. RxOutlook is published by the OptumRx Clinical Services Department Optum, Inc. All rights reserved. ORX6204B_ optum.com/optumrx 5

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