OptumRx generic pipeline forecast

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1 OptumRx generic pipeline forecast 2018 DAYTRANA methylphenidate Noven Therapeutics Transdermal patch All 2018 NORVIR ritonavir AbbVie Capsule; tablet All 2018 PROVENTIL HFA albuterol sulfate Merck Inhalation All 2018 TRAVATAN Z travoprost Alcon/Novartis Ophthalmic All 2018 ZAVESCA miglustat Actelion Capsule All 2018 SPRIX ketorolac Egalet Intranasal All 2018 TRACLEER bosentan Janssen Tablet All 2018 BETIMOL timolol Oak/Akorn Ophthalmic All 2018 SYPRINE trientine Valeant Capsule All 2018 BYETTA exenatide AstraZeneca Subcutaneous All 2018 FENTORA fentanyl Teva Tablet, buccal All 2018 INVANZ ertapenem Merck Intravenous All 2018 ADVAIR DISKUS fluticasone/salmeterol xinafoate GlaxoSmithKline Inhalation All SAMSCA tolvaptan Otsuka Tablet All 2018 TRISENOX arsenic trioxide Cephalon/Teva Intravenous All 2018 ZYTIGA abiraterone Janssen Tablet All 2018 EPOGEN epoetin alfa Amgen PROCRIT epoetin alfa Janssen Subcutaneous; intravenous Subcutaneous; intravenous All All KALETRA lopinavir/ritonavir AbbVie Tablet All 2018 SUPRENZA phentermine Citius/Akrimax Tablet, orally disintegrating All H GANIRELIX ganirelix acetate Organon/Merck Injection All H ZORTRESS everolimus Novartis Tablet All H WELCHOL colesevelam Daiichi Sankyo LOCOID hydrocortisone butyrate PreCision Dermatology/Valeant FORFIVO XL bupropion IntelGenX/Edgemont Tablet; oral suspension All H Lotion All Q All optum.com/optumrx 1

2 MAKENA hydroxyprogesterone caproate Lumara Health/Amag Pharmaceuticals Intramuscular All SENSIPAR cinacalcet Amgen Tablet All RESTASIS cyclosporine Allergan Ophthalmic All Q NAMENDA XR memantine Allergan All Q NUVARING etonogestrel/ ethinyl estradiol Merck Vaginal ring All ADCIRCA tadalafil Eli Lilly/United Therapeutics Tablet All BOTOX COSMETIC PULMICORT Flexhaler botulinum toxin type A Allergan Injection All budesonide AstraZeneca Inhalation All ABSTRAL fentanyl citrate Sentynl Tablet, sublingual All EMSAM selegiline Somerset/Mylan Transdermal patch All REMODULIN treprostinil United Therapeutics Injection All AMRIX cyclobenzaprine Cephalon All H PROAIR HFA albuterol sulfate Teva Inhalation All H LEVITRA vardenafil GlaxoSmithKline/Bayer Tablet All Q LETAIRIS ambrisentan Gilead Sciences Tablet All Q ACANYA clindamycin/benzoyl peroxide Valeant Gel All AMPYRA dalfampridine Acorda All XENICAL orlistat Roche Capsule All RITUXAN MOVIPREP rituxumab PEG-3350/sodium sulfate/sodium chloride/potassium chloride/sodium ascorbate/ascorbic acid Genentech/Roche/ Biogen Idec Intravenous All Salix/Valeant Oral solution All TOLAK fluorouracil Hill Dermaceuticals Cream All CIALIS tadalafil Eli Lilly Tablet All ALOXI palonosetron Helsinn/Eisai Intravenous All ENBREL etanercept Amgen Subcutaneous All Q NEULASTA pegfilgrastim Amgen Subcutaneous All Q RAPAFLO silodosin Allergan Capsule All Q PYLERA bismuth subcitrate potassium/ metronidazole/ tetracycline Allergan/Aptalis Capsule All Q optum.com/optumrx 2

3 STAXYN vardenafil Bayer Tablet, orally disintegrating All FINACEA azelaic acid Bayer Gel All ASTAGRAF XL tacrolimus Astellas BASAGLAR insulin glargine recombinant Eli Lilly/Boehringer Ingelheim All Subcutaneous All CANASA mesalamine Forest/Allergan Rectal suppository All ELIDEL pimecrolimus Valeant Cream All XOLAIR omalizumab Roche/Genentech Intravenous All CUVPOSA glycopyrrolate Merz Oral solution All 2019 ROZEREM ramelteon Takeda Tablet All 2019 TARCEVA erlotinib OSI Pharma/Genentech/ Pfizer Tablet All 2019 MINIVELLE estradiol Noven Transdermal patch All 2019 OMNARIS ciclesonide Sunovion/Takeda Intranasal All H FORTEO teriparatide Eli Lilly Injection All H HERCEPTIN trastuzumab Genentech/Roche Intravenous All Q BEPREVE bepotastine Bausch & Lomb/Valeant Ophthalmic All LATUDA lurasidone Sunovion Tablet All TEKTURNA aliskiren Novartis Tablet All ZYCLARA imiquimod Medicis Cream All ADVATE antihemophilic factor (recombinant), plasma/albuminfree method Baxalta Intravenous All GILENYA fingolimod Novartis Capsule All KORLYM mifepristone Corcept Tablet All RANEXA ranolazine Gilead All AZASITE azithromycin Akorn Ophthalmic All EMEND fosaprepitant dimeglumine Merck Intravenous All FASLODEX fulvestrant AstraZeneca Intramuscular All BENEFIX coagulation factor IX (recombinant) Pfizer Intravenous All CETROTIDE cetrorelix EMD Serono Subcutaneous All EXJADE deferasirox Novartis Tablet All optum.com/optumrx 3

4 FLECTOR diclofenac epolamine IBSA Institut Biochemique/Pfizer Transdermal patch All VESICARE solifenacin Astellas Tablet All EPANED KIT enalapril Silvergate Oral solution All LEVEMIR insulin detemir recombinant Novo Nordisk Subcutaneous All RESCRIPTOR delavirdine ViiV Healthcare Tablet All FIRAZYR icatibant Shire Subcutaneous All AVASTIN bevacizumab Genentech Intravenous All LYRICA pregabalin Pfizer Capsule; oral solution All STRIANT testosterone Auxilium Tablet All TORISEL temsirolimus Pfizer Injection All THALOMID thalidomide Celgene Capsule All EDLUAR zolpidem Meda/Orexo Tablet, sublingual All MYOBLOC botulinum toxin type B US WorldMeds Intramuscular All CYSTARAN cysteamine hydrochloride Sigma Tau Ophthalmic All JADENU deferasirox Novartis Tablet All VERMOX mebendazole Janssen Tablet, chewable All OSMOPREP sodium biphosphate/sodium phosphate Salix Tablet All TREANDA bendamustine Cephalon/Teva Intravenous 25 mg, 100 mg AMELUZ aminolevulinic acid Biofrontera Gel All DUREZOL difluprednate Alcon/Novartis Ophthalmic All APTENSIO XR methylphenidate Rhodes 2020 All MYCAMINE micafungin Astellas Intravenous All 2020 CIPRODEX ciprofloxacin/ dexamethasone Alcon/Novartis Otic All 2020 NOXAFIL posaconazole Merck Tablet; oral suspension All DALIRESP roflumilast AstraZeneca Tablet All SILENOR doxepin Pernix Tablet All JUXTAPID lomitapide Aegerion/Novelion Capsule All ELIGARD leuprolide QLT/Tolmar Subcutaneous All DELZICOL mesalamine Allergan Capsule, delayedrelease All optum.com/optumrx 4

5 SOMATULINE DEPOT TAYTULLA lanreotide Ipsen Subcutaneous All ethinyl estradiol/ norethindrone/ferrous fumarate Allergan Tablet All MOXEZA moxifloxacin Alcon/Novartis Ophthalmic All APTIVUS tipranavir Boehringer Ingelheim Capsule; oral solution All DEPO-SUBQ PROVERA medroxyprogesterone Pfizer Subcutaneous All CHANTIX varenicline Pfizer Tablet All NYMALIZE nimodipine Arbor Oral solution All DULERA MYDAYIS formoterol fumarate/ mometasone furoate amphetamine/ dextroamphetamine mixture Merck Inhalation All Shire DEXILANT dexlansoprazole Takeda Capsule, delayedrelease All All DENAVIR penciclovir Mylan Cream All LUCENTIS ranibizumab Roche Intravitreal All VELPHORO sucroferric oxyhydroxide Fresenius Tablet, chewable All UCERIS budesonide Valeant + = may launch during the stated date or later All optum.com/optumrx 5

6 optum.com/optumrx The information contained herein is compiled from various sources and is provided for informational purposes only. Due to factors beyond the control of OptumRx, information related to prospective drug launches is subject to change without notice. This information should not be solely relied upon for formulary decision-making purposes. OptumRx specializes in the delivery, clinical management and affordability of prescription medications and consumer health products. We are an Optum company a leading provider of integrated health services. Learn more at optum.com. All Optum trademarks and logos are owned by Optum, Inc. All other brand or product names are trademarks or registered marks of their respective owners. This document contains information that is considered proprietary to OptumRx and should not be reproduced without the express written consent of OptumRx. RxOutlook is published by the OptumRx Clinical Services Department Optum, Inc. All rights reserved. ORX6204B_ optum.com/optumrx 6

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