21 st Century Slide Based Pathology & Molecular Diagnostics: From the Laboratory to the Patient

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1 A meeting hosted by at The Tower Hotel Conference Centre St Katharine's Way, London E1W 1LD 21 st Century Slide Based Pathology & Molecular Diagnostics: From the Laboratory to the Patient For Registration Details go to Meeting Voice: You will need to enter the access code: UKNEQAS

2 PROVISIONAL PROGRAMME Friday 9 th November Registration and Buffet Lunch from 11.30am Welcome by Director: Keith Miller Welcome by UK NEQAS President Elect: Liam Whitby

3 Friday 9 th November Lung Cancer: pathology, personalised therapy & related biomarkers Companion Diagnostic Testing & Lung Cancer: The Birmingham Experience: Dr Phillipe Taniere, Consultant Pathologist, Queen Elizabeth Hospital Birmingham Personalized Medicine and Lung Cancer: Dr Shobhit Baijal, Consultant Medical Oncologist, Heartlands Hospital Birmingham : Performance of Participants in the ALK, ROS-1 & PD- L1 modules: Suzanne Parry, Scheme Manager Coffee and Trade Presentations by Commercial Companies (tbc) Tower Hotel Conference Room 2 Symposium sponsored by Roche Tissue Diagnostics Introduction by Chairman PD-L1 Biomarkers in Bladder Cancer and Personalised Healthcare Dr Mark Kockx, CEO & Lead Pathologist, Histogenex Dr Corrado D'Arrigo, Poundbury Cancer Institute Dr Philippe Taniere, Birmingham NHS Trust Prof Syed Hussain - Chair in Oncology Plymouth University Summary and discussion with all speakers The Merck Sharpe and Dohme pipeline.dr Serafino Pantano, Medical Affairs, MSD Introduction to NTRK testing for solid tumours: Dr Patricia Carrigan, Head Oncology Regulatory Affairs Companion Diagnostics, Bayer Pharmaceuticals Meeting ends There will be a Buffet Dinner on Friday Evening 9 th November from 19.30

4 Saturday 10 th November Targos/Roche Joint Symposium: Predictive Cancer Pathology of Lung & Urothelial Cancer 9.00 Introduction by Dr Eslie Dennis, Vice President Medical Affairs, Ventana & Professor Bharat Jasani, Director of Pathology, Targos Molecular Pathology GmbH 9.05 Immune Checkpoint Applications: An Overview & Update Dr Eslie Dennis. The Gerry Reynolds Lecture 9.50 PD-L1 Immune Checkpoint Analysis: Emerging Concepts: Professor Bharat Jasani Coffee & Trade PD-L1 Training Experience I: Microscopy vs Scanned Images: Dr Gudrun Baenfer, Head of Advanced Training Unit, Targos Molecular Pathology GmbH PD-L1 Training Experience II: Online Training: Dr Rolf Dietzko, Deputy Head of Advanced Training Unit, Targos Molecular Pathology GmbH PD-L1 IHC v NGS: Dr Erik Thunnissen, Consultant pathologist, VUMC, Amsterdam Lunch & Trade Tower Hotel Conference Room 2 Targos/ Roche/UKNEQAS-ICC&ISH Joint Symposium Predictive Cancer Pathology of Breast & GI Tract Cancer 8.30 Introduction by Professor Josef Reuschoff CMO, Targos Molecular Pathology GmbH & Dr Ian Frayling, Institute of Medical Genetics, University Hospital of Wales 8.35 Breast and Gastric cancer HER-2 updates: Professor Josef Reuschoff The evolving knowledge surrounding genetic abnormalities in the GI tract: Dr Ian Frayling, Institute of Medical Genetics, University Hospital of Wales 10.00: GI Tract cancer, biomarking & mismatch repair staining, problems and pitfalls: Professor Mark Arends, Head of Division of Pathology, University of Edinburgh Coffee & Trade 11.10: Predictive Markers in Breast Cancer: Andrew Dodson. Deputy Scheme Director, Ralph Lauren Centre for Breast Cancer Research, Royal Marsden Hospital Workshop I: HER2 IHC - Interpretation and scoring of difficult gastric and breast cancer cases: Dr Iris Nagelmeir, Targos Molecular Pathology GmbH Lunch & Trade

5 Saturday 10 th November Workshop 1a: PD-L1 IHC - Tumour Cell (TC) interpretation and scoring: Dr Kathrina Alexander, Pathology Unit, Targos Molecular Pathology GmbH Workshop 1b: PD-L1 IHC Immune Cell (ICP) interpretation and scoring: Dr Bryce Porter, Consultant Pathologist, Ventana Tea & Trade Workshop 1c: PD-L1 IHC Combined Positive Score (CPS) interpretation and scoring: Professor Bharat Jasani Panel Discussion with speakers Summing up and closing remarks by joint chairs Britannia Conference Room on 12 th Floor Visiopharm workshop on artificial intelligence in digital pathology Buffet Lunch provided Introduction by Dr Eslie Dennis & Dr Mark Kockx, CEO & Lead Pathologist, Histogenex 14.00: : Performance of participants in the GI tract EQA modules: Jamie Hughes, Deputy Scheme Manager 14.45: Experiences of a Participant: Hilary McBride, Belfast NHS Trust. Selected Topics Tea and Trade 15.45: Modernising pre-analytical practices in line with the needs of companion diagnostics testing: Dr Mark Kockx The Australian EQA Experience with companion testing: Julia Pagliuso, Scheme Manager for Tissue Disciplines, RCPAQAP 17.15: The IQNPath Digital Portal: Dr Sarah Wedden, CADQAS, Poundbury Cancer Institute Summing up and closing remarks by chairman. Meeting closes at Gala Dinner and Entertainment on Saturday evening 10 th of November 2018 from 19.30

6 Sunday 11 th November Digital Pathology 9.00 Introduction by Chairman: Suzanne Parry 9.05 The benefits of digital pathology to the NHS: Dr Bethany Williams, Leeds University Hospital 9.50 The possibilities offered by the use of artificial intelligence in slide-based pathology: Martin Kristensson, Visiopharm Selected Topics Refreshments & Trade UKNEQAS Molecular EQA: Dr Sandi Deans (tbc) BRAF testing in Melanoma: Dr Guy Orchard, St John s Dermatopathology, St Thomas s Hospital Commercial Talks Summing Up and Poster Presentations Lunch and depart Discovery Conference Room on 12 th Floor Roche Digital Slide Viewing and Education (limited attendance to 20 individuals per topic) From 10.00am MMR and BRAF IHC in CRC: Dr Bryce Portier DLL3 IHC in SCLC: Dr Richard Huang ALK IHC in NSCLC: Dr Bryce Portier 12.00: Additional viewing and discussion of IHC Stains: Dr Bryce Portier and Dr Richard Huang Coffee provided Lunch Britannia Conference Room on 12 th Floor Non-gynae cytology workshop: The quality of ICC on cytology samples - Is brown/red good enough? From 10.00amThis will be led by Dr Irena Srebotnik, Institute of Pathology, Faculty of Medicine, University of Ljubljana, Slovenia Coffee Provided Lunch

21 st Century Slide Based Pathology & Molecular Diagnostics: From the Laboratory to the Patient

21 st Century Slide Based Pathology & Molecular Diagnostics: From the Laboratory to the Patient A meeting hosted by UK NEQAS ICC & ISH at The Tower Hotel Conference Centre St Katharine's Way, London E1W 1LD 21 st Century Slide Based Pathology & Molecular Diagnostics: From the Laboratory to the Patient

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