Treatment Guidelines & Clinical Outcomes User Guide

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1 Treatment Guidelines & Clinical Outcomes User Guide For questions about McKesson Clinical Tools, us at

2 Treatment Guidelines and Clinical Outcomes User Guide Table of Contents Introduction to Treatment Guidelines and Clinical Outcomes... 3 Launching Treatment Guidelines... 5 Accessing Treatment Guidelines Materials... 6 Accepting Terms of Use...7 Selecting Treatment Guidelines... 8 Example of Treatment Guidelines... 9 Accessing Guideline Revisions...10 Example of Guideline Revisions Launching Clinical Outcomes Tables Accessing Efficacy Tables Example of Efficacy Table Accessing Side Effects Tables Example of Side Effects Table... 15

3 Introduction to Treatment Guidelines and Clinical Outcomes McKesson Treatment Guidelines provide clinical management support through a set of more than 30 evidence-based treatment standards backed by scientific literature and reviewed by nationally recognized experts. They serve as a comprehensive framework for cancer treatment management and provide practical information including recommendations for dosing and select supportive care for each regimen. Clinical Outcomes Tables offer practitioners an easy way to understand and compare the efficacy and side effects of the primary chemotherapy regimens used to treat cancer. They summarize key data in an easy to understand format that complements national guidelines. Information is based upon data reported in major clinical trials. Comprehensive framework for cancer treatment management More than thirty evidence-based treatment standards are reviewed and approved by nationally recognized experts Accessible online and regularly updated Key Benefits Practical information for improving patient care Treatment Guidelines enable practices to standardize and improve patient care. By utilizing treatment guidelines, a practice can guide and streamline clinical decisions across the clinic, ensuring consistency and efficiency. Guideline adherence can then be measured and ultimately leveraged to enable a practice to negotiate improved reimbursement with payers. Clinical Outcomes Tables provide practitioners with data from clinical trials to evaluate efficacy and side effects of regimens by diagnosis and treatment setting. Benefits for Practices Validated, scientific support for reimbursement Consistent, objective and unified clinical management Recommendations for dosing and supportive care for each regimen No additional cost to Onmark member practices

4 Highlights Treatment Guidelines and Clinical Outcomes Tables provide a detailed framework for cancer treatment management. The set of over thirty evidence-based treatment standards is supported by the latest scientific literature and approved by nationally recognized experts. Clinical Outcomes Tables offer practitioners an easy way to evaluate the relative efficacy and side effects of treatment regimens by diagnosis and treatment setting. Regularly reviewed and approved by nationally renowned cancer experts Are concise and easy to follow Are highly consistent with NCCN guidelines Provide specific dosing and cycling detail and supporting clinical trial evidence for each regimen recommendation (more specific than many NCCN guidelines) Serve as the foundation content from which other clinical tools are derived (Care Pathways, Treatment Orders, Patient Education) Eligible practices can measure guideline adherence through the Guideline Compliance Report available in the Reporting Center. To determine your eligibility to access these reports, contact your account representative.

5 Launching Treatment Guidelines Getting Started Log in to the Onmark website ( with your Onmark User ID and Password. If you have trouble logging in, please call After logging in: From the Top Navigation, choose Clinical From the Drop Down Menu, choose Clinical Tools From the next Drop Down Menu, choose Guidelines & Outcomes

6 Navigating Guidelines & Outcomes Pages Choose Access the Guidelines and Tables.

7 Terms of Use The Terms of Use Page will appear. Scroll to the bottom of the page to accept the Terms of Use. You must click I Accept these Terms to view the Pathways documents.

8 Accessing Treatment Guidelines Select the Diagnosis from the Drop Down Menu. Once the diagnosis is selected click on Guidelines.

9 A new window will open with the document selected. Example of Breast Cancer Health Guideline:

10 Accessing Guideline Revisions Select the Diagnosis from the Drop Down Menu then click on Guideline Revisions. Guideline Revisions identifies which areas of the Guideline were updated.

11 Example of Oropharyngeal Cancer Health Guideline Revisions

12 Launching Outcomes Outcomes tables summarize key data that complements the national guidelines - efficacy functions and side effects reported in major clinical trials. Accessing Clinical Outcomes - Efficacy Tables Select the Diagnosis from the Drop Down Menu then click on the Efficacy Table to be viewed. In the example below, Adjuvant and Neoadjuvant is selected under Efficacy Table.

13 Example of Breast Cancer Health Efficacy Table

14 Accessing Clinical Outcomes - Side Effects Tables Select the Diagnosis from the Drop Down Menu then click on the Side Effects Table to be viewed. In the example below, Adjuvant and Neoadjuvant is selected under Side Effects Tables.

15 Example of Breast Cancer Health Side Effects Table

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