Research Papers Title Conference, Collaborators Year

Transcription

1 Research Papers - Title Conference, Collaborators Year Redox regulation by model for electrolyzed-reduced functional Ayumi Hosokawa et.al. Analysis of nano particle on biological availability and toxicity Survival benefit of electrolyzed-reduced on nematode Analysis of inducible mechanism of cancer cell death by atomic hydrogen Examination of anti-diabetic effect of model for electrolyzed-reduced Suppressive effect of Electrolyzed Water with high dissolved Hydrogen (H2) on Cardiorenal syndrome of Dahl Salt sensitive rat Induction of apoptosis of cancer cells by atomic hydrogen produced by catalyst activity of platinum nanoparticles Use experience of electrolysis hemodialysis using electrolyzed-reduced Clinical evaluation of hemodialysis using electrolyzedreduced Case report of a patient accepted reduction of itch by dialysate using electrolyzed-reduced Examination of hemodialysis system using electrolyzed Use experience of electrolysis hemodialysis using at cathod side of electrolysis Effect of Electrolyzed-reduced on skin temperature of lower limb on hemodialysis patients Evaluation of from hemodialysis system by using electrolyzed-reduced Exploratory investigation about long-term clinical effect of electrolysis hemodialysis Examination of intake of electrolyzed on supressive effect of kidney injury in cronic kidney disease (CKD) model rat Fundamental investigation for supressive effect of intake of electrolyzed on cardiorenal organ dysfunction Biological effect of Electrolyzed Water in Hemodialysis Induction mechanism of cell death of cancer cells by atomic hydrogen Anti-diabetes effects of electrolyzed reduced and its model Redox regulation by electrolyzed reduced and its model functional Keishi Kadooka et.al. functional H. Yan et.al. functional Katsuhiko Shigiyama et.al. functional Takuro Nakamura et.al. Renal Week, American Society of Nephrology The 68th Annual Meeting of the Japanese Cancer Association Sanetaka Shirahata et.al. The joint meeting of the 76th Annual Meeting of thehokkaido Dialysis Therapy and the 36th Scientific Meeting of the Tohoku renal failure Susumu Uemura et.al. for Dialysis Therapy (Japan Kidney Week ) Koichi Ishibashiri et.al. for Dialysis Therapy (Japan Kidney Week ) Ryoichi Nakazawa et.al. for Dialysis Therapy (Japan Kidney Week ) Hiroshi Nemoto et.al. for Dialysis Therapy (Japan Kidney Week ) Susumu Uemura et.al. for Dialysis Therapy (Japan Kidney Week ) Akiko Kobayashi et.al. for Dialysis Therapy (Japan Kidney Week ) Minako Yataka et.al. for Dialysis Therapy (Japan Kidney Week ) The 52nd Annual Meeting of Japanese Society of Nephrology The 8th Scientific Meeting of the Japanese Society of Anti-Aging Medicine Nephron Clinical Practice ;112:c9 c15 Annual Meeting of Katsuhiko Shigiyama et.al. Annual Meeting of Takuro Nakamura et.al. Annual Meeting of Ayumi Hosokawa et.al. Page 1 of 9

2 Next-generation hemodialysis system for palliating The 6th Japan Congress Support of Home Dialysis lassitude after hemodaialysis The 9th Scientific Meeting of renal failure pathosis Electrolyzed at cathode side (EW) suppressed renal therapy injury in chronic kidney disease rats The 9th Scientific Meeting of renal failure pathosis Collaboration for clinical effect of electrolysis hemodialysis therapy Electrolyzed at cathode side (EW) suppressed renal Renal Week, American Society of Nephrology injury in chronic kidney disease rats The 21st Annual and International Meeting of Growth suppression of HL60 and L6 cells by atomic Technology hydrogen K. Nakanishi et.al. Suppresive effects of hydrogen and atomic hydrogen on type 2 diabetes Supressive effect of electrolyzed reduced on lipid peroxidation and lipid absorption Elongation of lifespan of nematode by electrolyzed reduced Inducible effect of cancer cell death by electrolyzed - reduced and it's model Antidiabetic effect of electrolyzed -reduced and it's model Examination of hemodialysis system using electrolyzed Investigation of biocompatibility about Hemodialysis solution (HD) by Electrolyzed (EW) Protective effect of electrolyzed cathodic on diabetic nephropathy Potential of intake of electrolyzed (Alkaline ion ) in countermeasure for chronic kidney disease Intake of electrolyzed cathodic reduce excretion of urine protein of streptozotocin-induced diabetes Dahl S rat. Investigation of participation of methylglyoxal on Cardiorenal syndrome Kinetic analysis of superoxide anion radical-scavenging and hydroxyl radical-scavenging activities of platinum nanoparticles. Examination of electrolyzed-reduced on survival benefit of nematode Suppressive effect of Electrolyzed-reduced Water on Lipid peroxidation and absorption Inhibitory Effect of Electrolyzed Reduced Water on Tumor Angiogenesis Antioxidative effect of electrolyzed-reduced supplemented with platinum nanoparticle and effects on parkinson model animal Diabetes prevention through redox regulation by reduced The 21st Annual and International Meeting of Technology K. Haramaki et.al. The 21st Annual and International Meeting of Technology M. Abe et.al. The 21st Annual and International Meeting of Technology H. Yan et.al. The annual meeting of West Japan of Japan Society for Bioscience, K. Kadekaru et.al. The annual meeting of West Japan of Japan Society for Bioscience, K. Haramaki et.al. The 36th Scientific Meeting of the Tohoku renal failure Hiroshi Nemoto et.al. The 53th Annual Meeting of the Japanese Society for Dialysis Therapy The 8th Scientific Meeting of the Japanese Society of Anti-Aging Medicine Takefumi Mori et.al. The 8th Scientific Meeting of the Japanese Society of Anti-Aging Medicine The 51st Annual Meeting of Japanese Society of Nephrology Yusuke Osaki et.al. Vascular Medicine vol.4 no Langmuir, June, Web on line Takeki Hamasaki et.al. Annual Meeting of H. Yan et.al. Annual Meeting of Masumi Abe et.al. Biological & Pharmaceutical Bulletin 31(1),19-26, January Jun YE et.al. The 4th meeting of the Japanese Soiety for Functional Water (Hakodate) Akitami Sato et al The 4th meeting of the Japanese Soiety for Functional Water (Hakodate) Page 2 of 9

3 Redox regulation and diabetes prevention by reduced Redox regulation by reduced s as active hydrogen donors and intracellular ROS scavengers for prevension of diabetes Induction of caspase-3-dependent apoptosis by electrolyzed reduced /platimum nanoparticels in cancer cells Analysis of superoxide anion and hydroxyl radical scavenging activities by platinum nanoparticle Suppressive effect of reduced with reactive species scavenging activity on type 1 diabetes mellitus Electrolyzed reduced supplemented with platinum nanoparticles suppresses promotion of two-stage cell transformation Analysis of hydroxyl radical scavenging activity by platinum nanoparticle Medical application of reduced as reactive species scavenger and active hydrogen donor Platimum nanoparticels in electrolyzed reduced induces apoptosis in cancer cells Suppression of two-stage cell transformation by electrolyzed reduced /platinum nanocolloids Suppression of Invasion of Cancer Cells and Angiogenesis by Electrolyzed Reduced Water Suppression of Two-stage Cell Transformation by Electrolyzed Reduced Water/Platinum Nanocolloids Mechanism for suppressive effect of reduced with reactive species scavenging activity on diabetes Suppression of apoptosis by reduced in nerve cells Effect of reduction of platinum nanocolloids and electrolyzed-reduced on nerve cells Induction of cancer cell-specific apoptosis by electrolyzed-reduced /platinum nanoparticels Reaction kinetics analysis of reactive species scavenging activity of platinum nanocolloids Reduced functions as active hydrogen donors and ROS scavengers Technology (Tokyo), The joint meeting of west Japan and Hokkaido of (Fukuoka) Kiichiro Teruya et al The 19th European Society for Animal Cell Technology Meeting (Harrogate, UK) The 19th European Society for Animal Cell Technology Meeting (Harrogate, UK) Agrochemistry (Sapporo) Agrochemistry (Sapporo) Cytotechnology The 3rd meeting of the Japanese Soiety for Functional Water (Tokyo) The 17th Annual Meeting of the Japanese Association for Animal Cell Technology(Nagoya) S. Shirahata The 17th Annual Meeting of the Japanese Association for Animal Cell Technology(Nagoya) The 17th Annual Meeting of the Japanese Association for Animal Cell Technology(Nagoya) World Congress on In Vitro Biology(USA) Y. Jun et al World Congress on In Vitro Biology(USA) Tenyou Ishikawa et al Suppression of carcinogenesis mutation formation at promortion stage by electrolyzed-reduced /platinum nanocolloid Characteristic analysis of reduced s as active Characteristic analysis of platinum nanocolloids as active Page 3 of 9

4 Suppressive effect of reduced against alloxan induced type 1 diabetes mellitus Effects of Electrolyzed-Reduced Water on the Matrix Metalloproteinase-2 Activities and In Vitro Invasion of Human Fibrosarcoma HT1080 Cells Induction of apoptosis by platinum nanocolloids/electrolyzed reduced in cancer cells Electrolyzed-reduced protects nerve cells from glutamic acid toxicity Suppression of apoptosis by reduced in nerve cells Suppression of two-stage carcinogenic focus formation by electrolyzed-reduced / platinum nanocolloids Function analysis of platinum nanocolloids as active J. Ye et al Tenyou Ishikawa et al The joint meeting of West Japan and Cyugoku Sikoku of Biotechnology, and Agrochemistry,West Japan of Japanese Society of Nutrition and Food Science,West Japan of The Japanese Society for Food Science and Technology (Kagoshima) Toshifumi Imada et al The joint meeting of West Japan and Cyugoku Sikoku of Biotechnology, and Agrochemistry,West Japan of Japanese Society Suppressive effect of electrolyzed-reduced /platinum of Nutrition and Food Science,West Japan of The nanocolloids on proliferation of cancer cells Japanese Society for Food Science and Technology (Kagoshima) Suppression of carcinogenic focus formation by electrolyzed-reduced /platinum nanocolloids Suppressive effect of electrolyzed-reduced against nerve cell death induced by oxidative stress Scavenging of reactive species and suppressive effect on cell growth by hydrogen-platinum nano colloids Suppressive effect of reduced on pancreatic β-cells damage caused by oxidative stress Suppressive effect of reduced on the apoptotic cell death triggered by oxidative stress in pancreatic β HIT- T15 cells Physiological functions of platinum nanocolloides as scavengers against reactive species HT 1080 cells by electrolyzed-reduced Suppressive effect of electrolyzed-reduced on glutamic acid induced nerve cytotoxicity Suppressive effect of reduced on the apoptotic cell Analysis of mechanisim for differentiation induceded by electrolyzed- reduced in K562 human leukemia cells Japanese Society of Nutrition and Food Science (Fukuoka) 18th ESACT Meetings(Spain) 18th ESACT Meetings(Spain) Page 4 of 9

5 HT1080 cells by electrolyzed-reduced Inhibition of glutamic acid neuron toxicity by electrolyzed reduced Suppressive effect of reduced on the apoptotic cell Analysis of electrolyzed reduced as a differentiation inducing mechanism for K562 human leukemia cells HT1080 cells by electrolyzed-reduced Inhibition of glutamic acid neuron toxicity by electrolyzed reduced Suppressive effect of reduced on the apoptotic cell Analysis of electrolyzed reduced as a differentiation inducing mechanism for K562 human leukemia cells Antioxidative effect of electrolyzed-reduced supplemented with platinum nanoparticle and effects on parkinson model animal Diabetes prevention through redox regulation by reduced Redox regulation and diabetes prevention by reduced Redox regulation by reduced s as active hydrogen donors and intracellular ROS scavengers for prevension of diabetes Induction of caspase-3-dependent apoptosis by electrolyzed reduced /platimum nanoparticels in cancer cells Analysis of superoxide anion and hydroxyl radical scavenging activities by platinum nanoparticle Suppressive effect of reduced with reactive species scavenging activity on type 1 diabetes mellitus Electrolyzed reduced supplemented with platinum nanoparticles suppresses promotion of two-stage cell transformation Analysis of hydroxyl radical scavenging activity by platinum nanoparticle Medical application of reduced as reactive species scavenger and active hydrogen donor Platimum nanoparticels in electrolyzed reduced induces apoptosis in cancer cells The 4th meeting of the Japanese Soiety for Functional Water (Hakodate) Akitami Sato et al The 4th meeting of the Japanese Soiety for Functional Water (Hakodate) Technology (Tokyo), The joint meeting of west Japan and Hokkaido of (Fukuoka) Kiichiro Teruya et al The 19th European Society for Animal Cell Technology Meeting (Harrogate, UK) The 19th European Society for Animal Cell Technology Meeting (Harrogate, UK) Agrochemistry (Sapporo) Agrochemistry (Sapporo) Cytotechnology The 3rd meeting of the Japanese Soiety for Functional Water (Tokyo) The 17th Annual Meeting of the Japanese Association for Animal Cell Technology(Nagoya) S. Shirahata The 17th Annual Meeting of the Japanese Association for Animal Cell Technology(Nagoya) Page 5 of 9

6 Suppression of two-stage cell transformation by electrolyzed reduced /platinum nanocolloids Suppression of Invasion of Cancer Cells and Angiogenesis by Electrolyzed Reduced Water Suppression of Two-stage Cell Transformation by Electrolyzed Reduced Water/Platinum Nanocolloids Mechanism for suppressive effect of reduced with reactive species scavenging activity on diabetes Suppression of apoptosis by reduced in nerve cells Effect of reduction of platinum nanocolloids and electrolyzed-reduced on nerve cells Induction of cancer cell-specific apoptosis by electrolyzed-reduced /platinum nanoparticels Reaction kinetics analysis of reactive species scavenging activity of platinum nanocolloids Reduced functions as active hydrogen donors and ROS scavengers Suppression of carcinogenesis mutation formation at promortion stage by electrolyzed-reduced /platinum nanocolloid The 17th Annual Meeting of the Japanese Association for Animal Cell Technology(Nagoya) World Congress on In Vitro Biology(USA) Y. Jun et al World Congress on In Vitro Biology(USA) Tenyou Ishikawa et al Characteristic analysis of reduced s as active Characteristic analysis of platinum nanocolloids as active Suppressive effect of reduced against alloxan induced type 1 diabetes mellitus Effects of Electrolyzed-Reduced Water on the Matrix Metalloproteinase-2 Activities and In Vitro Invasion of Human Fibrosarcoma HT1080 Cells Induction of apoptosis by platinum nanocolloids/electrolyzed reduced in cancer cells Electrolyzed-reduced protects nerve cells from glutamic acid toxicity Suppression of apoptosis by reduced in nerve cells Suppression of two-stage carcinogenic focus formation by electrolyzed-reduced / platinum nanocolloids J. Ye et al Tenyou Ishikawa et al The joint meeting of West Japan and Cyugoku Sikoku of,west Japan of Function analysis of platinum nanocolloids as active Japanese Society of Nutrition and Food Science,West Japan of The Japanese Society for Food Science and Technology (Kagoshima) Toshifumi Imada et al Suppressive effect of electrolyzed-reduced /platinum nanocolloids on proliferation of cancer cells The joint meeting of West Japan and Cyugoku Sikoku of,west Japan of Japanese Society of Nutrition and Food Science,West Japan of The Japanese Society for Food Science and Technology (Kagoshima), Page 6 of 9

7 Suppression of carcinogenic focus formation by electrolyzed-reduced /platinum nanocolloids Suppressive effect of electrolyzed-reduced against nerve cell death induced by oxidative stress Scavenging of reactive species and suppressive effect on cell growth by hydrogen-platinum nano colloids Suppressive effect of reduced on pancreatic β-cells damage caused by oxidative stress Suppressive effect of reduced on the apoptotic cell death triggered by oxidative stress in pancreatic β HIT- T15 cells Physiological functions of platinum nanocolloides as scavengers against reactive species HT 1080 cells by electrolyzed-reduced Suppressive effect of electrolyzed-reduced on glutamic acid induced nerve cytotoxicity Suppressive effect of reduced on the apoptotic cell Analysis of mechanisim for differentiation induceded by electrolyzed- reduced in K562 human leukemia cells HT1080 cells by electrolyzed-reduced Inhibition of glutamic acid neuron toxicity by electrolyzed reduced Suppressive effect of reduced on the apoptotic cell Analysis of electrolyzed reduced as a differentiation inducing mechanism for K562 human leukemia cells HT1080 cells by electrolyzed-reduced Inhibition of glutamic acid neuron toxicity by electrolyzed reduced Suppressive effect of reduced on the apoptotic cell Japanese Society of Nutrition and Food Science (Fukuoka) 18th ESACT Meetings(Spain) 18th ESACT Meetings(Spain) Analysis of electrolyzed reduced as a differentiation inducing mechanism for K562 human leukemia cells Page 7 of 9

8 Title Summary Conference, Collaborators Year Inhibiting effect of functional on formation of fatty acid inhibit formation of fatty acid peroxides, and (Sendai) peroxides antiarteriosclerotic effects are anticipated. Yoko Sugihara et al Reduced was found to inhibit damage Protective effect of reduced to pancreatic β-cells caused by alloxan, against alloxan induced which triggers type-1 diabetes, and to (Sendai) damage to pancreatic β-cells promote insulin secretion. Makoto Kaminishi et al Suppressive effect of electrolyzed reduced on nerve cell death caused by oxidative stress Suppressive effect of electrolyzed reduced on multiplication of human leukemia cells Suppression of lipid peroxidation by electrolyzed reduced Electrolyzed reduced induces differentiation in K562 human leukemia cells. Suppression of glutamateinduced neural death of PC12 cells by electrolyzed reduced Protective action of reduced against alloxan-induced cytotoxicity in pancreatic β-cell suppress nerve cell death caused by oxidative stress. inhibit multiplication of human leukemia cells and to induce differentiation into normal cells. inhibit peroxidation of linoleic acid and cellular membranes. induce megakaryocytic differentiation in human leukemia cells. inhibit glutamate-induced death of PC12 nerve cells. Reduced was found to provide protection against alloxan-induced cytotoxicity in pancreatic β-cells. Page 8 of 9 (Sendai) (Sendai) 15th meeting of JAACT, Tokyo 15th meeting of JAACT, Tokyo 15th meeting of JAACT, Tokyo 15th meeting of JAACT, Tokyo Protective mechanism of By eliminating active, reduced Cytotechnology, 40, reduced against alloxaninduced pancreatic β-cell damage: Scavenging effect was found to provide protection against pancreatic β-cell damage due to alloxan toxicity. against reactive species Phenotypic changes in tumor cells induced by electrolyzed inhibit the formation of malignant, reduced phenotype colonies by tumor cells Joint Conference of Kansai, West Japan, Chugoku, and Shikoku Chapters Hirofumi Nogami et al Antidiabetic effectiveness of Both electrolyzed reduced and natural electrolyzed reduced and, reduced were found to promote sugar natural reduced Joint Conference of Kansai, West uptake into muscle tissue and to improve Japan, Chugoku, and Shikoku glucose tolerance disorders in model mice Chapters with type-2 diabetes. Makoto Kaminishi et al Phenotypic changes in tumor cells induced by electrolyzed reduced Suppressive effect of electrolyzed-reduced on the growth of cancer cells and microorganisms Anti-oxidative improves diabetes Study of cancer-inhibiting effects of electrolyzed reduced Inhibition of cancerous characteristics by reduced inhibit metastasis and infiltration of cancer cells. inhibit the proliferation of cancer cells and microorganisms. Provides a comprehensive explanation of the effectiveness of anti-oxidative in improving diabetes. Using electrolyzed reduced to suppress the secretion of proteolytic enzymes by cancer cells was found to inhibit metastasis and infiltration of cancer cells. inhibit characteristics associated with metastasis and infiltration of cancer cells. Japanese Association for Animal Cell Technology (Kyoto) Hirofumi Nogami et al 17th ESACT Meeting (Sweden) th ESACT Meeting (Sweden) 2001 Taichi Hara et al 2000 Japanese Tissue Culture Association (Okayama) Kiichiro Teruya et al 2000

9 Study of cancer-inhibiting effects of electrolyzed reduced Effects of electrolyzed reduced on sugar uptake signal pathways Electrolyzed and natural reduced exhibit insulinlike activity on glucose uptake into muscle cells and adipocytes Effects of electrolyzed reduced in eliminating active and protecting against oxidative damage to DNA Effects of electrolyzed reduced in inhibiting proliferation of cancer cells Telomere shortening in cancer cells by reduced. Electrolyzed-reduced scavenges active species and protects DNA from oxidative damage. inhibit metastasis and infiltration of cancer cells. inhibit the growth of cancer cells and to induce phenotypical changes. promote glucose uptake into muscle cells and adipocytes in a manner similar to insulin. eliminate superoxide radicals produced in a test tube. It also suppressed DNA damage caused by active. inhibit proliferation of cancer cells and to induce phenotypical changes. induce telomere shortening and deterioration in cancer cells. eliminate superoxide radicals produced in a test tube. It also suppressed DNA damage caused by active Taichi Hara et al 1999 Masaaki Oda et al The 16th meeting of the European Society for Animal Cell Technology 1999 Masaaki Oda et al Eri Murakami et al The joint international meeting of the Japanese Association for Animal Cell Technology (JAACT) and the European Society for Animal Cell Technology (ESACT) Biochemical and Biophysical Research Communications, 234, Page 9 of 9