Resin splint as a new conservative treatment for ingrown toenails
|
|
- Laurence Nichols
- 6 years ago
- Views:
Transcription
1 321 ORIGINAL Resin splint s new onservtive tretment for ingrown toenils Kzuy Mtsumoto 1, Ihiro Hshimoto 2, Hideki Nknishi 2, Yoshiki Kuo 3, Kzutoshi Muro 3, nd Seiji Arse 3 1 Setion of Plsti nd Reonstrutive Surgery, Kitjim Tok Hospitl ; 2 Deprtment of Plsti nd Reonstrutive Surgery, nd 3 Deprtment of Dermtology, Institute of Helth Biosienes, the University of Tokushim Grdute Shool, Tokushim, Jpn Astrt : Severl onservtive s well s surgil methods re used for the tretment of ingrown toenils until dte. The onservtive methods re either sed on nil splinting or on orthonyxi, ut no methods employing oth priniples hve een reported thus fr. Moreover, surgil methods usully involve postopertive pin, prolonged wound heling nd restrited tivities of dily living. Therefore, onsidering the need of simplified, non-invsive method, in this study, we pplied novel splint to tret ptients with ingrown toenils nd estimted the linil effiy s well s rte of reurrene following tretment. The splint is plte mde of resin tht is tthed to the lterl edge of the nil using ndge. We studied 61 ptients (19 men nd 42 women ; men ge 36 yers), with n verge pplition durtion of 9.3 months nd n verge follow-up period of 10 months in ll ptients. All ptients experiened pin relief within week of splint pplition nd derese in the degree of nil deformity. Moreover, follow-up reveled reurrene rte of 8.2%. Therefore, we elieve tht this new devie is n exellent onservtive tretment method for ptients with ingrown toenils. J. Med. Invest. 57 : , August, 2010 Keywords : Bre, ingrown nil, nil deformity, orthonyxi, splint INTRODUCTION An ingrown toenil is one of the most ommon onditions enountered in the outptient lini nd it frequently ffets dolesents nd young dults (1, 2). This ondition, whih is often onsidered trivil nd inonsequentil, my led to onsiderle disomfort, pin nd inonveniene, nd restrits Reeived for pulition June 10, 2010 ; epted July 29, Address orrespondene nd reprint requests to Kzuy Mtsumoto, Setion of Plsti nd Reonstrutive Surgery, Kitjim Tok Hospitl, 30-1 Az-Kwkuo, Tihm, Kitjimho, Itno- gun, Tokushim , Jpn nd Fx : tivity (1). Conservtive nd surgil methods re ville for treting this ondition. Surgil tretments, however, risk postopertive pin nd neessitte postopertive rest nd wound dressing, therey hindering tivities of dily living, often ginst the ptient s preopertive wishes. Consequently, simplified onservtive method ws developed (1). A fine polyethylene tue with slit ws used s gutter to protet the lterl nil groove from the trum used y the irregulr or ingrowing lterl nil edge. Susequently, severl onservtive nilsplinting tehniques me to e developed sed on the gutter tretment priniple (2-4). Another onservtive method (re tretment) in whih the The Journl of Medil Investigtion Vol
2 322 K. Mtsumoto, et l. A new tretment for ingrown toenils shpe of the over-urved nil is orreted using dynmi orthonyxi tehniques ws lso developed (5-7). However, thus fr, no method hs employed the priniples of oth nil splinting nd orthonyxi. Therefore, we hve developed novel tretment method in whih unique resin plte ts s re s well s splint to ptients ingrown toenils. MATERIALS AND METHODS We performed retrospetive study of 61 ptients with ingrown toenils [19 men nd 42 women ; men ge 36 yers (rnge 9-69 yers)]. All ptients omplined of pin in the ffeted toe. Ptients in whom the soft tissue hd grown round the nil were exluded from the study. We used novel splint, whih ws mde of resin (Pediglss Corp. ; Osk, Jpn) nd ws folded k to 2 mm width t one end (Fig. 1). After lening the nil nd the djent tissue with n ntisepti, the distl setion of the lterl edge of the nil ws hooked using the tip of the folded prt of the splint nd ndge ws tthed only to the lterl edge of the nil. The splint ws then tilted y pplying dequte fore so s to orret the urvture of the ffeted nil nd fixed in this position using quik-drying dhesive. The superfluous prt of the splint, inluding the Figure 2. Resin plte tthed to the nil edge. The superfluous prt of the splint, inluding the thik hndle setion, ws removed using nippers () nd grinder (). After grinding, prt of the plte remins dhered to the nil (). Figure 1. nils. The new resin splint for the tretment of ingrown thik hndle setion, ws removed using nippers nd grinder (Fig. 2), nd the entire surfe of the nil, inluding the splint, ws overed with sheet of glss fire nd dhesive gel (Fig. 3). During tretment, dily tivities of living were unrestrited nd the ptients were instruted to use nil file insted of nil lipper for nil re. The splint ws repled every 6 weeks. The verge durtion of splint plement ws 9.3 months (rnge 3-33 months) nd the verge follow-up ws 10.0 months (rnge 3-65 months).
3 The Journl of Medil Investigtion Vol. 57 August RESULTS All ptients reported pin relief t the 1-week follow-up. In ses where inorret trimming of the toenil hd used pin, pplition of our splint relieved pin immeditely nd enled the nil to grow over the lterl nil fold (Fig. 4). The verge Figure 3. The left hllux of 36-yer-old femle ptient shown efore () nd fter () pplition of the splint, sheet of glss fire, nd dhesive gel. The splint ws fixed to the lterl side of the left hlf of the nil (rrow). The degree of nil deformity ws estimted y referring to our lssifition tle (Tle 1). A nil with no urvture ws lssified s 0 wheres ylindril nil ws lssified s 100. Nils with urvture etween these extreme vlues were lssified in the rnge of All ptients were evluted for the degree of nil urvture nd pin intensity t 1 week fter splint fixtion nd t 3 months fter the ompletion of tretment. Tle 1. The lssifition tle used to estimte the degree of nil deformitiy. Degree of deformity Referene shpes d Figure 4. The left hllux of 19-yer-old femle ptient. The lterl orner of the nil tht ws ut too short exerted sustntil pressure on the nil wll nd this used pin ( nd ). After 10- month tretment period, the degree of nil deformity ws redued to 30 from 40 nd the pressure ws distriuted long the lterl edge of the nil. During 5- yer follow- up period, there ws no reurrene ( nd d).
4 324 K. Mtsumoto, et l. A new tretment for ingrown toenils nil urvture ws 55.4 nd 34.4 t the initition nd termintion of tretment, respetively. In ptients with severe degree of nil urvture, longterm pplition ws required (Fig. 5). Of the 61 ptients, only 5 reported reurrene. d Figure 5. The right hllux of 56-yer-old femle ptient shown efore ( nd ) nd fter ( nd d) 3-month onservtive tretment using the resin splint. The degree of nil deformity ws redued to 30 from 60. DISCUSSION Mny possile uses of ingrown toenils hve een proposed (8) ; nonetheless, there seems to e generl onsensus tht inresed pressure etween the lterl order of the nil nd the nil wll uses pin nd promotes development of pronyhi (5). All therpeuti mesures used for ingrown nils im to relieve this pressure. These tehniques n e lssified s surgil or onservtive. Although mny surgil pprohes suh s lssi wedge exision nd prtil mtrix phenoliztion hve evolved, these surgil modlities hve mny disdvntges, suh s prolonged wound heling nd restrition of tivities of dily living, srring nd deformtion (1). Moreover, surgil tretments for ingrown toenils re thought to e extremely ggressive nd unneessry euse they involve destrution of the nil mtrix nd onsequent nil disfigurement (4). Thus, severl uthors prefer onservtive methods to invsive surgil ones (1-5). These noninvsive onservtive tretment methods n e divided into two groups. The first group inludes tehniques sed on nil splinting. The gutter tretment is representtive of this group (1). Although vrious types of mterils hve een used s the gutter in studies of nil-splinting tehniques, the si priniple remins the sme. Nil splinting seprtes the nil plte from the soft tissue so s to provide hnnel for the nil to grow (3). Ari et l. used vinyl intrvenous drip infusion tue s the gutter splint. Simultneously, they lso used sulptured nil (ryli rtifiil nil) on n ingrown nil with nil loss nd no grnultion tissue s prostheses nd suitle fixtion for gutter splints. They ttriuted the effiy of the splints nd sulptured nils to their protetion of the surrounding soft tissue ginst distl penetrting spiules nd lterl serrted nil edges (4). The seond group inludes methods sed on orthonyxi tht employs diret fore to orret the deformity of n over-urved nil plte. This priniple is dynmi in ontrst with the splint tehnique, whih is sed on stti priniple. Hrrer et l. suessfully used new orthonyxi devie in ptients with ingrown toenils (2). Two metl hooks on ilterl sides of the nil plte re fixed in ple under tension y twisting onneting wire etween the hooks. The edges of the nil re lifted from the nil fold nd the pressure exerted on the inflmed soft tissue is relesed immeditely. A modified devie in whih dentl string is used insted of the
5 The Journl of Medil Investigtion Vol. 57 August onneting wire in the originl devie hs lso een reported (6). Moreover, super-elsti wire hs lso een used s soure of dynmi restortion fore (7). Two holes re mde t the distl free edge of the nil plte in the white portion. The wire is inserted into these holes nd then ut with lippers so tht it does not protrude from the nil. The ovementioned dynmi tretments n improve the shpe of the nil itself s well s relese the pressure on the nil fold ; this improvement of nil shpe my result from ontinuous long-term tension on the nil plte. Our method using the resin plte is sed on the priniple of nil splinting. The plte is integrted with the nil nd funtions s sulptured nil. Simultneously, diret fore deresing the degree of nil urvture is exerted upon the nil plte. This is the first proedure tht uses the splinting nd dynmi orthonyxi tehniques together. With regrd to reurrene rtes, onsiderle vrition is oserved mong onservtive tretments. In nil-splinting studies, the rte ws 8.7% with the flexile plsti tue (3), 13.3% with the vinyl tue nd the ryli rtifiil nil (4) nd 44-48% with the fine polyethylene tue (1). In the dynmi orthonyxi studies, the reurrene rte ws 19% in the proedures using the hooks nd wire (5) nd 28.6% with the hooks nd the dentl string (6). In the present study, pin reurred in 5 of 61 ptients (8.2%). We reommended the ptients to ontinue with the splinting till the urvture of the deformed nil ws redued to less thn 30 nd most ptients epted this reommendtion. This resulted in lower reurrene rte thn for other reported methods. We exluded ptients with grnultion tissue formtion euse the exudte from the grnultion tissue hindered dhesion etween the splint nd the nil plte. We nnot deny the possiility tht this seletive exlusion my hve led to the exlusion of ritil ses nd ould thus e responsile for our good results. However, the use of our method provides erly relief from pin nd the proedure itself is pinless. It is lso superior with respet to esthetis euse the resin devie eomes lmost pelluid nd invisile fter the proedures. In our opinion, it is n exellent proedure euse of its linil effiieny nd the low reurrene rte. This proedure is indited in ptients with ingrown toenils without grnultion formtion, espeilly in those who hd ut their toenils too short during nil trimming. However, the intensity of the restortion fore is weker in our methods thn in the other dynmi orthonyxi tretments. This my prolong the pplition period. We hope tht inresing the elstiity of the resin plte my inrese its ility to orret the defet, nd onsequently, shorten the pplition period of the devie. ACKNOWLEDGEMENTS Finnil support : NONE, Conflit of Interest : NONE. REFERENCES 1. Wlle WA, Milne DD, Andrew T : Gutter tretment for ingrowing toenils. Br Med J 21 : , Nzri S : A simple nd prtil method in tretment of ingrown nils : splinting y flexile tue. J Eur Ad Dermtol Venereol 20 : , Kim YJ, Ko JH, Choi KC, Lee CG, Lim KJ : Nil-splinting tehnique for ingrown nils : the therpeuti effets nd the proper removl time of the splint. Dermtol Surg 29 : 745-8, Ari H, Ari T, Nkjim H, Hneke E : Formle ryli tretment for ingrowing nil with gutter splint nd sulptured nil. Int J Dermtol 43 : , Hrrer J, Shöffl V, Hohenerger W, Shneider I : Tretment of ingrown toenils using new onservtive method. A prospetive study ompring re tretment with Emmert s proedure. J Am Poditr Med Asso 95 : 542-9, Erdogn FG, Erdogn G : Long-term results of nil re pplition in dieti ptients with ingrown nils. Dermtol Surg 34 : 84-87, Moriue T, Yoned K, Moriue J, Mtsuok Y, Nki K, Yokoi I, Niu N, Miymoto I, Kuot Y : A simple therpeuti strtegy with super elsti wire for ingrown toenils. Dermtol Surg 34 : , Sher RK : Toenil disorders. Clin Dermtol 1 : , 1983
P AND K IN POTATOES. Donald A Horneck Oregon State University Extension Service
P AND K IN POTATOES Donld A Hornek Oregon Stte University Extension Servie INTRODUCTION Phosphorous nd potssium re importnt to grow high yielding nd qulity pottoes. Muh of the northwest hs hd trditionlly
More informationEFFECT OF DIETARY ENZYME ON PERFORMANCE OF WEANLING PIGS
EFFECT OF DIETARY ENZYME ON PERFORMANCE OF WEANLING PIGS Finl report sumitted to Dniso Animl Nutrition E. vn Heugten nd B. Frederik North Crolin Stte University, Deprtment of Animl Siene Summry The urrent
More informationWhangarei District Council Class 4 Gambling Venue Policy
Whngrei Distrit Counil Clss 4 Gmling Venue Poliy April 2013 Whngrei Distrit Counil Clss 4 Gmling Venue Poliy Tle of ontents Introdution... 3 1 Ojetives of the poliy in so fr s promoted y the Gmling At
More informationIntroduction to Study Designs II
Introdution to Study Designs II Commonly used study designs in publi helth & epidemiologi reserh Benjmin Rihrd H. Muthmbi, DrPH, MPH Stte HIV Epidemiologist HIV Epidemiology Investigtion Setion PA Deprtment
More informationSoft tissue management: the key to the success of periodontal treatment
DOI: 10.1051/odfen/2017010 J Dentofil Anom Orthod 2017;20:305 The uthors Soft tissue mngement: the key to the suess of periodontl tretment A. Popelut 1 Hospitl University Assistnt Leturer in Periodontology,
More informationET 100 EXTERIOR FRONT DOOR BLACK OUT TAPE INSTALLATION
100 EXTERIOR FRONT DOOR BLCK OUT TPE INSTLLTION The procedure descried elow is for the LH side. Use the sme procedure for oth the RH nd LH sides, unless otherwise specified. 1. INSTLL NO. 2 BLCK OUT TPE
More information6.1.8 Intraarticular impacted proximal humeral fracture with displacement 11-C2
Author Mihel Pleko 6.1.8 Intrrtiulr impted proximl humerl frture with displement 11-C2 1 Cse desription 75-yer-old very tive womn, fell on the stirs in her house. Lived lone efore the ident, did ll housework
More informationSevere Gummy Smile with Class II Malocclusion Treated with LeFort I Osteotomy Combined with Horseshoe Osteotomy and Intraoral Vertical Ramus
2013 67 1 5560 Severe Gummy Smile with Clss II Mlocclusion Treted with LeFort I Osteotomy Comined with Horseshoe Osteotomy nd Introrl Verticl Rmus Osteotomy * 56 Shimo et l. Act Med. Okym Vol. 67, No.
More informationDoes Excision of Heterotopic Ossification of the Elbow Result in Satisfactory Patient-Rated Outcomes?
Mlysin Orthopedi Journl 2017 Vol 11 No 1 Doi: http://dx.doi.org/10.5704/moj.1703.017 Sndeep KN, et l Does Exision of Heterotopi Ossifition of the Elow Result in Stisftory Ptient-Rted Outomes? Sndeep KN,
More informationVariations in burn perfusion over time as measured by portable ICG fluorescence: A case series
Burns & Trum, Otoer 2014, Vol 2, Issue 4 Cse Report Vritions in urn perfusion over time s mesured y portle ICG fluoresene: A se series Shrmil Dissnike, Senn Adul-Hmed, John A. Griswold Deprtment of Surgery,
More informationLHb VTA. VTA-projecting RMTg-projecting overlay. Supplemental Figure 2. Retrograde labeling of LHb neurons. a. VTA-projecting LHb
SUPPLEMENTARY INFORMATION Supplementl Figure 1 doi:10.1038/nture09742 Lterl 1.0 mm from midline mpfc BNST mpfc BNST Lterl 2.1 mm from midline LHA LHA Lterl 2.7 mm from midline SUPPLEMENTAL INFORMATION
More informationGingival recession: part 3. Surgical management using free grafts and guided tissue regeneration
Gingivl reession: prt 3. Surgil mngement using free grfts nd guided tissue regenertion M. Ptel, 1 P. J. Nixon 2 nd M. F. W.-Y. Chn 3 VERIFIABLE CPD PAPER IN BRIEF Free grfts re n lterntive to pedile grfts
More informationMuneo MIYASAKA, Tadashi AKAMATSU, Akihisa Yamazaki, Teruyuki Ochiai Rica Tanaka, Yuko Sakuma, *Noriaki SAKATA, *Ryoichi NIIKIRA
Toki J Exp Clin Med., Vol. 33, No. 1, pp. 21-27, 2008 new devie for Fixing the Premxill with osteotomy in hild with omplete ilterl left lip nd Plte in the Mixed dentition Period - Preliminry se report-
More informationInput from external experts and manufacturer on the 2 nd draft project plan Stool DNA testing for early detection of colorectal cancer
Input externl experts nd mnufcturer on the 2 nd drft project pln Stool DNA testing for erly detection of colorectl cncer (Project ID:OTJA10) All s nd uthor s replies on the 2nd drft project pln Stool DNA
More informationThe split denture: A new technique for artificial saliva reservoirs in mandibular dentures
CLINICAL NOTE Austrlin Dentl Journl 2003;48:(3):190-194 The split denture: A new tehnique for rtifiil sliv reservoirs in mndiulr dentures AR Mendoz,* MJ Tomlinson Astrt Xerostomi is reltively ommon omplint
More informationGingival recession: part 3. Surgical management using free grafts and guided tissue regeneration
Gingivl reession: prt 3. Surgil mngement using free grfts nd guided tissue regenertion M. Ptel, 1 P. J. Nixon 2 nd M. F. W.-Y. Chn 3 VERIFIABLE CPD PAPER IN BRIEF Free grfts re n lterntive to pedile grfts
More informationAnkle arthrodesis has long been the traditional
Originl Artile Trnsfiulr nkle rthrodesis: A novel method for nkle fusion A short term retrospetive study S Muthukumr Blji, V Selvrj, Sthish Devdoss, Annmli Devdoss Astrt Bkground: Ankle rthrodesis hs long
More informationEffects of Enzyme Inducers in Therapeutic Efficacy of Rosiglitazone: An Antidiabetic Drug in Albino Rats
Asin J. Exp. Si., Vol. 21, No. 2, 2007, 00-00 Effets of Enzyme Inuers in Therpeuti Effiy of Rosiglitzone: An Antiieti Drug in Alino Rts Ann Chursi,#* P.K. Krr** A. S. Mnn* & M.D. Khry* * Deprtment of Phrmeutil
More informationInvasive Pneumococcal Disease Quarterly Report July September 2018
Invsive Pneumococcl Disese Qurterly Report July Septemer Introduction Since 17 Octoer 2008, invsive pneumococcl disese (IPD) hs een notifile to the locl Medicl Officer of Helth under the Helth Act 1956.
More informationPoultry No The replacement value of betaine for DL-methionine and Choline in broiler diets
Poultry No. 1573 The replement vlue of etine for DL-methionine nd Choline in roiler diets Key Informtion In roiler diets defiient in sulfur mino ids ut dequtely supplemented with methyl groups vi dded
More informationC LINICAL A RTICLE. Abstract. Introduction. Page 52 / SA ORTHOPAEDIC JOURNAL Summer 2007
Pge 52 / SA ORTHOPAEDIC JOURNAL Summer 2007 C LINICAL A RTICLE Physel r resetion for prtil growth plte rrest HR Hos,* Registrr S Dix-Peek,* FCS(SA)Orth, Consultnt RN Dunn,* FCS(SA)Orth, Consultnt N Wieselthler,**
More informationSpecific Immunotherapy in Atopic Dermatitis Four- Year Treatment in Different Age and Airborne Allergy Type Subgroups
At Dermtovenerol Crot 2006;14(4):230-240 CLINICAL ARTICLE Speifi Immunotherpy in Atopi Dermtitis Four- Yer Tretment in Different Age nd Airorne Allergy Type Sugroups Mgdlen Czrnek-Operz, Wojieh Silny Deprtment
More informationStudy of Stress Distribution in the Tibia During Stance Phase Running Using the Finite Element Method
Ksetsrt J. (Nt. Sci.) 48 : 729-739 (2014) Study of Stress Distriution in the Tii During Stnce Phse Running Using the Finite Element Method Thepwchr Ruchirh 1, Tumrong Puttpitukporn 1, * nd Siriporn Ssimontonkul
More informationPeanut (Arachis hypogaea L.) Response to Bradyrhizobia Inoculant Applied In-furrow with Agrichemicals
Penut (Arhis hypoge L.) Response to Brdyrhizoi Inoulnt Applied In-furrow with Agrihemils Dvid L. Jordn*, P. Dewyne Johnson, Rik L. Brndenurg, nd Joel Firloth 1 ABSTRACT Brdyrhizoi is often pplied in the
More informationOther Uses for Cluster Sampling
Other Uses for Cluster Smpling Mesure hnges in the level of n ttriute Hypothesis testing versus intervl estimtion Type I n 2 errors Power of the test Mesuring ttriute t sme time in ifferent sites Exmple:
More informationAJ PUTT. Hematology. Chemistry. Species: Canine Gender: Female Year of Birth: 2013 Client: PUTT
Speies: Cnine Gender: Femle Yer of Birth: 2013 Client: PUTT Requisition #: 9034-12 Aession #: W2152816 Aount Code: 72364 Veterinrin: CARTER Pnel/Profile: Tik Pnel Add-on Senior Profile with L 4Dx Plus
More informationUsing Paclobutrazol to Suppress Inflorescence Height of Potted Phalaenopsis Orchids
Using Pcloutrzol to Suppress Inflorescence Height of Potted Phlenopsis Orchids A REPORT SUBMITTED TO FINE AMERICAS Linsey Newton nd Erik Runkle Deprtment of Horticulture Spring 28 Using Pcloutrzol to Suppress
More informationPerspective Management of Advanced Fibrosis in the Context of Hepatitis C Virus Infection
Perspetive Mngement of Advned Firosis in the Context of Heptitis C Virus Infetion Advned firosis my e present in sustntil proportion of individuls with symptomti, hroni heptitis C virus (HCV) infetion,
More informationFRAMEstar. 2-Component PCR Plates
FRAMEstr -Component Pltes FrmeStr two-omponent tehnology redues evportion from pltes, improving results nd llowing for volume redutions to sve on expensive regents. FrmeStr pltes mximise therml stility
More informationEFFECT OF SOYBEAN CYST NEMATODE ON GROWTH OF DRY BEAN. Research Report to Northarvest Bean Growers, January 19, 2009
EFFECT OF SOYBEAN CYST NEMATODE ON GROWTH OF DRY BEAN Reserh Report to Northrvest Ben Growers, Jnury 19, 29 Berlin D. Nelson, Susilo Poromrto, n Ruell Goswmi, Dept. Plnt Pthology, NDSU Ojetive: Determine
More informationchapter 7. Colposcopic terminology: the 2011 IFCPC nomenclature
hpter 7. Colposopi terminology: the 2011 IFCPC nomenlture CHAPTER 1 CHAPTER 1 In ny rnh of siene, progress evolves from ler understnding of previous reserh nd experiene. Clrity of terminology nd prtie
More informationTOURNAMENT REGULATIONS INDOOR COMPETITIONS
TOURNAMENT REGULATIONS INDOOR COMPETITIONS Jnury 2015 INTERNATIONAL HOCKEY FEDERATION CONTENTS 1 Rules of ompetition 2 Tournment Offiils 3 Tem entry 4 Pre-tournment riefing meetings 5 Composition of tem
More informationMeat and Food Safety. B.A. Crow, M.E. Dikeman, L.C. Hollis, R.A. Phebus, A.N. Ray, T.A. Houser, and J.P. Grobbel
Met nd Food Sfety Needle-Free Injection Enhncement of Beef Strip Loins with Phosphte nd Slt Hs Potentil to Improve Yield, Tenderness, nd Juiciness ut Hrm Texture nd Flvor B.A. Crow, M.E. Dikemn, L.C. Hollis,
More informationSummary of Package Insert 1
Summry of Pckge Insert 1 For Sttes with Non-Published Policies Indictions Non-infected prtil nd full-thickness skin ulcers due to VSU 2 of greter thn 1 month durtion nd which hve not dequtely responded
More informationSupplementary Figure 1. Scheme of unilateral pyramidotomy used for detecting compensatory sprouting of intact CST axons.
() BDA 2 weeks fter Py () AAVs Cre or GFP t P1 BDA 2 weeks fter Py CSMN CST () Py t P7 or 2 months () Py t 2 months Supplementry Figure 1. Sheme of unilterl pyrmidotomy used for deteting ompenstory sprouting
More informationMinimum effective dose of chenic acid for gallstone patients: reduction with bedtime administration and
Gut, 1982, 23, 28-284 Minimum effetive dose of heni id for gllstone ptients: redution with bedtime dministrtion nd low holesterol diet D P MUDGL, R M KUPFER, ND T C NORTHFIELD* From the Normn Tnner Gstroenterology
More informationstatic principle: output determined by a connection with strong node dynamic principle: output (sometimes) determined by a weak (floating) node
stti n ynmi priniple pmos network nmos network v out stti priniple: output etermine y onnetion with strong noe ynmi priniple: output (sometimes) etermine y wek (floting) noe hrging: C s is eing hrge up
More informationCurrent concepts on the management of tooth wear: part 3. Active restorative care 2: the management of generalised tooth wear
Current onepts on the mngement of tooth wer: prt 3. Ative restortive re 2: the mngement of generlised tooth wer S. B. Meht, 1 S. Bnerji, 2 B. J. Millr 3 nd J.-M. Surez-Feito 4 VERIFIABLE CPD PAPER IN BRIEF
More informationWesternBright Quantum
WesternBright Quntum Quntify hemiluminesent Western lots over wie ynmi rnge WesternBright Quntum is new hemiluminesent regent speilly formulte for CCD imging. This novel Horserish peroxise (HRP) sustrte
More informationNormal Pressure Hydrocephalus after Myodil Myelography
Cse Norml Pressure Hydroephlus fter Myodil Myelogrphy Ezgi Akr, Mehmet Ufuk Akmil Hydrpş Numune Trining nd Reserh Hospitl, Deprtment of Neurosurgery, Istnul, Turkey Astrt Ojetive: Ft-sturted ontrst gent-enhned
More informationPrime Enrollees Consumer Watch NHC Patuxent River FY 2016 Defense Health Cost Assessment & Program Evaluation
Prime Enrollees Consumer Wtch NHC Ptuxent River 16 Defense Helth Cost Assessment & Progrm Evlution NHC Ptuxent River: Smple size-1,457 Response rte-1.2% Source: Helth Cre Survey of DoD Beneficiries Inside
More informationImpressions in implant dentistry
Impressions in implnt dentistry S. Bhkt, 1 J. Vere, 2 I. Clder 3 nd R. Ptel 4 IN BRIEF Aims to introdue the generl dentl prtitioner to the rmmentrium of implnt dentistry nd provide instrutions for mking
More informationNTSE-2013(Stage-I) (For Class X Students) ENGLISH LANGUAGE TEST
NTSE-2013(Stge-I) (For Clss X Stuents) ENGLISH LANGUAGE TEST Time: 40 Minutes Mximum Mrks: 40 Diretion: Choose the wor tht is most nerly opposite in mening to the given wors in Question No. 51 to 54. 51.
More informationDemineralization effects of hydrogen peroxide on bovine enamel and relation of shear bond strength of brackets
Pulition Copyright Deminerliztion effets of hydrogen peroxide on ovine enmel nd reltion of sher ond strength of rkets Sntigo González-López /Crmen Lui Sores G. de Medeiros /Cmejo-Aguilr Defren /Mri Vitori
More informationWSU Tree Fruit Research and Extension Center, Wenatchee (509) ext. 265;
FINAL REPORT WTFRC Project # AH-1-5 WSU Project # 13C-355-3 Project title: PI: Orgniztion: Coopertors: of Sunburn in Apples with RAYNOX Lrry Schrder, Horticulturist WSU Tree Fruit Reserch nd Extension
More informationFull-Mouth Adhesive Rehabilitation of a Severely Eroded Dentition: The Three-Step Technique. Part 2.
Full-Mouth Adhesive Rehilittion of Severely Eroded Dentition: The Three-Step Tehnique. Prt 2. Frnes Vilti, MD, DMD, MS Senior Leturer, Dept of Fixed Prosthodontis nd Olusion Shool of Dentl Mediine, University
More informationPROVEN ANTICOCCIDIAL IN NEW FORMULATION
PROVEN ANTICOCCIDIAL IN NEW FORMULATION Coxidin 100 microgrnulte A coccidiosttic dditive for roilers, chickens rered for lying nd turkeys Contins 100 g of monensin sodium per kg Aville s homogenous grnules
More informationPNEUMOVAX 23 is recommended by the CDC for all your appropriate adult patients at increased risk for pneumococcal disease 1,2 :
PNEUMOVAX 23 is recommended y the CDC for ll your pproprite dult ptients t incresed risk for pneumococcl disese 1,2 : Adults ged
More informationUniversity of Groningen
University of Groningen The prevlene of sesonl ffetive disorder in the Netherlnds Mersh, PPA; Middendorp, HM; Bouhuys, Antoinette; Beersm, DGM; vn den Hoofdkker, RH; Middendorp, Hermine M. Pulished in:
More informationSUPPLEMENTARY INFORMATION
doi:10.1038/nture10754 Supplementry note 1 To ompre our dt with previous studies, we mesured the width of spikes from identified dopminergi neurons nd unidentified neurons from DATCre mie. Previous studies
More informationReduction in albumin binding function following liver resection in patients with and without cirrhosis
Originl Artile Redution in lumin inding funtion following liver resetion in ptients with nd without irrhosis Penglei Ge 1,2, Wenjun Lio 1, Huyu Yng 1, Jingfen Lu 3, Wei Xu 1, Dndn Hu 1, Shund Du 1, Hifeng
More informationThe effect of manure, zeolite and soil ageing in the dynamics of hexavalent chromium in Cichorium spinosum
1 3 4 6 7 8 9 1 11 1 13 14 1 16 17 18 19 1 3 4 6 7 8 9 3 31 3 33 34 3 The effet of mnure, zeolite nd soil geing in the dynmis of hexvlent hromium in Cihorium spinosum V. Antonidis, T. Polyzois, S. Petropoulos,
More informationRadiographic evaluation of the technical quality of undergraduate endodontic competence cases in the Dublin Dental University Hospital: an audit
Rdiogrphic evlution of the technicl qulity of undergrdute endodontic competence cses in the Dulin Dentl University Hospitl: n udit Précis: An udit exmining the technicl qulity of undergrdute endodontic
More informationLesions of prefrontal cortex reduce attentional modulation of neuronal responses. and synchrony in V4
Lesions of prefrontl ortex reue ttentionl moultion of neuronl responses n synhrony in V4 Georgi G. Gregoriou,, Anrew F. Rossi, 3 Leslie G Ungerleier, 4 Roert Desimone 5 Deprtment of Bsi Sienes, Fulty of
More informationHYPERBILIRUBINEMIA BY RICARDO KATZ, HECTOR DUCCI, AND HERNAN ALESSANDRI
INFLUNC OF CORTISON AND PRDNISOLON ON HYPRBILIRUBINMIA BY RICARDO KATZ, HCTOR DUCCI, AND HRNAN ALSSANDRI (From the Deprtment of Mediine, University of Chile Medil Shool, Hospitl Slvdor, Sntigo, Chile)
More informationVardenafil enhances clitoral and vaginal blood flow responses to pelvic nerve stimulation in female dogs
Interntionl Journl of Impotene Reserh (3) 15, 137 141 & 3 Nture Pulishing Group All rights reserved 955-993/3 $25. www.nture.om/ijir Vrdenfil enhnes litorl nd vginl lood flow responses to pelvi nerve stimultion
More information308 nm excimer lamp in combination with topical tacrolimus: A retrospective study of its efficacy and safety in childhood vitiligo
ORIGINAL ARTICLE 308 nm excimer lmp in comintion with topicl tcrolimus: A retrospective study of its efficcy nd sfety in childhood vitiligo BS Chndrshekr, N Shoh, P Deprtment of Dermtology, Cutis, Acdemy
More informationIranian Food Science and Technology Research Journal Vol. 6, No. 3, Fall, 2010.
Irnin Food Siene nd Tehnology Reserh Journl Vol. 6, No. 3, Fll, 2010. rvghi.mrym@gmil.om C ( AOAC 920.87 AOAC 942.05 AOAC 962.09 AOAC 922.06 AOAC 925.10 AACC 1- Extrusion-Expelling 2- Protein Dispersiility
More informationSYNOPSIS Final Abbreviated Clinical Study Report for Study CA ABBREVIATED REPORT
Finl Arevited Clinicl Study Report Nme of Sponsor/Compny: Bristol-Myers Squi Ipilimum Individul Study Tle Referring to the Dossier (For Ntionl Authority Use Only) Nme of Finished Product: Yervoy Nme of
More informationSurgical Neurology International
Surgil Neurology Interntionl OPEN ACCESS For entire Editoril Bord visit : http://www.surgilneurologyint.om Editor: Jmes I. Ausmn, MD, PhD University of Cliforni, Los Angeles, CA, USA Originl Artile True
More informationTOURNAMENT REGULATIONS HOCKEY INDIA SANCTIONED ALL INDIA TOURNAMENTS
TOURNAMENT REGULATIONS HOCKEY INDIA SANCTIONED ALL INDIA TOURNAMENTS Mrh 2015 INTERNATIONAL HOCKEY FEDERATION CONTENTS 1 Rules of ompetition 2 Tournment Offiils 3 Tem entry 4 Pre-tournment riefing meetings
More information3. DRINKING WATER INTAKE BACKGROUND KEY GENERAL POPULATION STUDIES ON DRINKING WATER INTAKE RELEVANT GENERAL POPULATION
3. DRINKING WATER INTAKE...1 3.1. BACKGROUND...1 3.2. KEY GENERAL POPULATION STUDIES ON DRINKING WATER INTAKE 1 3.3. RELEVANT GENERAL POPULATION STUDIES ON DRINKING WATER INTAKE...9 3.4. PREGNANT AND LACTATING
More informationBSC 2094C MOCK EXAM A
BSC 2094C MOCK EXAM A PART A: Multiple Choie True/Flse Items 1. Vriose veins re hrterized by. 1. tortuous nd irregulr diltions in superfiil veins due to inompetent vlves 2. being used by prolonged bk pressure
More informationReference-Based Digital Concept to Restore Partially Edentulous Patients Following an Immediate Loading Protocol: A Pilot Study
Referene-Bsed Digitl Conept to Restore Prtilly Edentulous Ptients Following n Immedite Loding Protool: A Pilot Study Ali Thmse, DDS, PhD 1 /Rent De Clerk, DDS 2 /Steven Ekert, DDS, MS 3 /Dniel Wismeijer,
More informationLALR Analysis. LALR Analysis. LALR Analysis. LALR Analysis
LLR nlysis Motivtion s eplined efore, in LR() prsers there re mny more sttes thn in the previous procedures, LR() nd LR(). This is ecuse there re sttes which contin the sme configurtions, ut with different
More informationJOURNAL OF APPLIED ORAL SCIENCE, BAURU-SP, v. 20, n. 6, supl. 18, Part 1-2, pp , NOV-DEC,
Universidde de São Pulo Biliote Digitl d Produção Inteletul - BDPI Sem omunidde WoS 2013-08-02 Rehilittive tretment of left lip nd plte: experiene of the Hospitl for Rehilittion of Crniofil Anomlies -
More informationLearning to see: experience and attention in primary visual cortex
2 Nture Pulishing Group http://neurosi.nture.om rtiles Lerning to see: experiene nd ttention in primry visul ortex 2 Nture Pulishing Group http://neurosi.nture.om Roy E. Crist, Wu Li nd Chrles D. Gilert
More informationCongenital heart defects involving an Anomalous Origin of the
Dign Interv Rdiol 2012; 18:547 551 Turkish Soiety of Rdiology 2012 CARDIOVASCULAR IMAGING CASE REPORT Progressive intr-individul rdition dose redution during CT surveillne of ptient with ALCAPA syndrome
More informationSUPPLEMENTARY INFORMATION
DOI: 1.13/n7 Reltive Pprg mrna 3 1 1 Time (weeks) Interspulr Inguinl Epididyml Reltive undne..1.5. - 5 5-51 51-1 1-7 7 - - 1 1-1 Lipid droplet size ( m ) 1-3 3 - - - 1 1-1 1-1 1-175 175-3 3-31 31-5 >5
More informationARTICLE. E. O. List & A. J. Palmer & D. E. Berryman & B. Bower & B. Kelder & J. J. Kopchick
Dietologi (2009) 52:1647 1655 DOI 10.1007/s00125-009-1402-z ARTICLE Growth hormone improves ody omposition, fsting lood gluose, gluose tolerne nd liver triylglyerol in mouse model of diet-indued oesity
More informationTOURNAMENT REGULATIONS INDOOR COMPETITIONS
TOURNAMENT REGULATIONS INDOOR COMPETITIONS Novemer 2017 INTERNATIONAL HOCKEY FEDERATION CONTENTS 1 Rules of ompetition 2 Tournment offiils 3 Tem entry 4 Pre-tournment riefing meetings 5 Composition of
More informationTHE EVALUATION OF DEHULLED CANOLA MEAL IN THE DIETS OF GROWING AND FINISHING PIGS
THE EVALUATION OF DEHULLED CANOLA MEAL IN THE DIETS OF GROWING AND FINISHING PIGS THE EVALUATION OF DEHULLED CANOLA MEAL IN THE DIETS OF GROWING AND FINISHING PIGS John F. Ptience nd Doug Gillis SUMMARY
More informationAnti-Tumour Necrosis Factor-alpha Therapy in Crohn s Disease: Clinical and Health Economic Aspects
Anti-Tumour Nerosis Ftor-α Therpy in Crohn s Disese Anti-Tumour Nerosis Ftor-lph Therpy in Crohn s Disese: Clinil n Helth Eonomi Aspets Fion MGuire, 5th yer Meiine ABSTRACT Ojetives: Crohn s isese is hroni,
More informationThallium-201 chloride scintigraphy in soft tissue tumors
136 ORIGINAL Thllium-201 chloride scintigrphy in soft tissue tumors Hideki Otsuk, Kori Terzw, Nomi Morit, Yoichi Otomi, Shoichiro Tko, Seiji Iwmoto, Kyosuke Oski, Msfumi Hrd, nd Hiromu Nishitni Deprtment
More informationRotoroll OK! User's Guide
Rotoroll Pge Sfety preution. The user must never open Rotoroll to inspet it, reple prts or unertke repirs. The reeling mehnisms spring my pop out of its set n use mge n injury to persons, nimls n ojets
More informationShear behaviour of regular and irregular rock joints under cyclic conditions
Pper No. 69 ISMS 2016 Sher ehviour of regulr n irregulr rok joints uner yli onitions S. M. Mhi Niktr, *, K. Seshgiri Ro, Amit Kumr Shrivstv Deprtment of Civil Engineering, Inin Institute of Tehnology Delhi,
More informationBilateral Ankle Fusion in Leak Syndrome Induced Deformity: A Case Report
Cse Report Journl of Orthopedi Cse Reports 2017 Mr-Apr: 7(2):52-56 Bilterl Ankle Fusion in Lek Syndrome Indued Deformity: A Cse Report Luis Sorl 1, An C Ângelo 1, Afonso Cetno 1, Joquim Rodei 1, Isel Ros
More informationEvaluation of Results of Locking Compression Plate in Distal Femur Fractures
Originl Article Print ISSN: 2321-6379 Online ISSN: 2321-595X DOI: 10.17354/ijss/2018/110 Evlution of Results of Locking Compression Plte in Distl Femur Frctures Anuj Kumr Ll 1, S K Kushik 2, Utkl Gupt
More informationCAUSES OF DIARRHEA, PNEUMONIA, AND ABORTION IN 1991 CATTLE SUBMISSIONS TO THE KSU VETERINARY DIAGNOSTIC LABORATORY
CAUSES OF DIARRHEA, PNEUMONIA, AND ABORTION IN 1991 CATTLE SUBMISSIONS TO THE KSU VETERINARY DIAGNOSTIC LABORATORY 1 1 2 R. K. Frnk, M. W. Vorhies, nd M. M. Chengpp Summry Cuses of dirrhe, pneumoni, nd
More informationAdiabatic CMOS Circuit Design: Principles and Examples
Aditi CMOS Ciruit Design: Priniples nd Exmples X.Wu,G.Hng,ndM.Pedrm Astrt: In view of hnging the type of energy onversion in CMOS iruits nd therey hieving ultr-low-power design, this pper investigtes diti
More informationSOME MECHANISTIC CONCEPTS IN ELECTROPHILIC ADDITION REACTIONS TO C=C BONDS
SM MANISTI NPTS IN LTPILI AITIN ATINS T = BNS The = ond is considered to e wek se/nucleophile. The high concentrtion of electron density mkes the pi ond Lewis se, ut in order to donte electrons the pi
More informationNovel rechargeable calcium phosphate nanoparticlecontaining
(217) 9, 24 32 www.nture.om/ijos OPEN ORIGINAL ARTICLE Novel rehrgele lium phosphte nnoprtileontining orthodonti ement Xin-Ju Xie 1,2, Dn Xing 2,3, Lin Wng 2,4, Hn Zhou 2, Mihel D Weir 2, Yu-Xing Bi 1
More informationNowadays, particulate filler composite resin (PFC)
Pulition Fire-reine Composite in Clinil Dentistry Sufyn K. Groushi 1, Lippo V.J. Lssil 1, Pekk K.Vllittu 1 Astrt: The use of fire-reine omposite (FRC) tehnology in linil entistry my solve mny of the prolems
More informationA critical assessment of different transmethylation procedures commonly employed in the fatty acid analysis of aquatic organisms
LIMNOLOGY nd OCEANOGRAPHY: METHODS Limnol. Oenogr.: Methods 6, 2008, 523 531 2008, y the Amerin Soiety of Limnology nd Oenogrphy, In. A ritil ssessment of different trnsmethyltion proedures ommonly employed
More informationA maternal junk food diet in pregnancy and lactation promotes an exacerbated taste for junk food and a greater propensity for obesity in rat offspring
British Journl of Nutrition (27), pge 1 of 9 q The uthors 27 doi: 1.117/S7114781237 mternl junk food diet in pregnny nd lttion promotes n exerted tste for junk food nd greter propensity for oesity in rt
More informationNeighbourhood Watch London
Neighbourhood Wth ondon Presenttion to Counity & Protetive ervies Coittee= Ot 25,24 Presented by: N. Wilson - 24 President Neighbourhood Wth ondon Prepred by: J.Andruhow- Progr Mnger Neighbouhood Wth ondon
More informationXXI COMMONWEALTH GAMES
XXI COMMONWEALTH GAMES Gold Cost (AUS) 4 / 15 April 2018 COMPETITION REGULATIONS MEN S AND WOMEN S HOCKEY COMPETITIONS Pulished: 20 Ferury 2018 INTERNATIONAL HOCKEY FEDERATION CONTENTS 1 Interprettion
More informationFunding: MPIC/Agrochemical Industry USDA/ARS
Evaluation and omparison of iofungiides and fungiides for the ontrol of post harvest potato tuer diseases. E. Gahango, W. W. Kirk, P. S. Wharton, R. Shafer and P. Tumalam. Department of Plant Pathology,
More informationGENERAL TOURNAMENT REGULATIONS OUTDOOR COMPETITIONS
GENERAL TOURNAMENT REGULATIONS OUTDOOR COMPETITIONS Otoer 2016 INTERNATIONAL HOCKEY FEDERATION CONTENTS 1 Rules of ompetition 2 Tournment Offiils 3 Tem entry 4 Pre-tournment riefing meetings 5 Composition
More informationWrite down the correct answer for each of the following computations. Try to complete
Prtil Nursing Clultions y Vl Hext n Lii Myner, 2003 MODULE SIX: COMPLEX CALCULATIONS ASSESSMENT TWO: Complex Meition Aministrtion Write own the orret nswer for eh of the following omputtions. Try to omplete
More informationChloride Nutrition Regulates Water Balance in Plants
XII Portuguese-Spnish Symposium on Plnt Wter Reltions Chloride Nutrition Regultes Wter Blne in Plnts Frno-Nvrro JD 1, Brumós J, Rosles MA 1, Vázquez-Rodríguez A 1, Sñudo BJ 1, Díz- Rued P 1, Rivero C 1,
More informationResult of Short Term Studentship in Homoeopathy (STSH) 2016
Result of Short Term Studentship in Homoeopathy (STSH) 2016 LIST OF STUDENTS PPROVED FOR WRDING SHOLRSHIP S.N Name STSH No. Title ollege Grades Status 1. S.. Karthi STSH160047 PLEO ONTROLLED OMPRTIVE STUDY
More informationFinite-Dimensional Linear Algebra Errata for the first printing
Finite-Dimensionl Liner Algebr Errt for the first printing Mrk S. Gockenbch Jnury 6, 011 The following corrections will be mde in the second printing of the text, expected in 011. Pge 41: Exercise 5: S
More informationCASE REPORT. Abstract. Introduction. Case Reports
CASE REPORT Ulertive Colitis-ssoited Cner/Dysplsi Deteted Using Surveillne Colonosopy Performed in the Clinil Remission Phse: A Report of Five Cses Ruiko Murok 1, Keiihi Toming 1, Xuin Si 1, Kzuhiro Tkenk
More informationEmergency decompressive craniectomy after removal of convexity meningiomas
OPEN ACCESS For entire Editoril Bord visit : http://www.surgilneurologyint.om Editor: Jmes I. Ausmn, MD, PhD University of Cliforni, Los Angeles, CA, USA Originl Artile Emergeny deompressive rnietomy fter
More informationmanage excessive exudate, thereby protecting peri-wound skin and facilitating wound healing.
A clinicl cse-series evlution of supersorent dressing on exuding wounds l Ojective: To evlute the cpcity of supersorent dressing (DryMx Extr; Asorest AB) to mnge excessive exudte, therey protecting peri-wound
More informationLATE RESULTS OF TRANSFER OF THE TIBIAL TUBERCLE FOR RECURRENT DISLOCATION OF THE PATELLA1
LATE RESULTS OF TRANSFER OF THE TIBIAL TUBERCLE FOR RECURRENT DISLOCATION OF THE PATELLA1 W. G. J. HAMPSON nd P. HILL, BRISTOL, ENGLAND The uthors wished to determine the lte results of the Huser opertion,
More informationArthroscopic Anatomy of Shoulder
Arthroscopic Antomy of Shoulder Murt Bozkurt, Mehmet Emin Simsek, nd Hlil İrhim Açr 2 2.1 Introduction In the lst 30 yers, shoulder rthroscopy hs ecome of greter importnce in the dignosis nd tretment of
More informationThe pitfalls of bedside regional cerebral oxygen saturation in the early stage of post cardiac arrest
Kinoshit et l. Sndinvin Journl of Trum, Resusittion nd Emergeny Mediine (2015) 23:95 DOI 10.1186/s13049-015-0173-4 COMMENTARY The pitflls of edside regionl ererl oxygen sturtion in the erly stge of post
More informationOnce small always small? To what extent morphometric characteristics and postweaning starter regime affect pig lifetime growth performance
Huting et l. Porine Helth Mngement (2018) 4:21 https://doi.org/10.1186/s40813-018-0098-1 RESEARCH Open Aess One smll lwys smll? To wht extent morphometri hrteristis nd postwening strter regime ffet pig
More information