S Potassium K mmol/l Up to 1m m - 1y >1y /07/2010. S Chloride CL mmol/l Up to 3m > 3m /07/2010

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Roberta Harrell
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1 Northumbria Healthcare NHS Trust Clinical Chemistry Deartment Reference Ranges Reference Ranges in use in Telepath Laboratory System at July 2005 unless indicated otherwise Last date Amended; 20/08/2010 Amended by AJP Spec Expanded d Telepath nits Age range Telepath Ranges as comments Date &E S Sodium Na mmol/l p to 1m m - 1y >1y /07/2010 S Potassium K mmol/l p to 1m m - 1y >1y /07/2010 S Chloride CL mmol/l p to 3m > 3m /07/2010 S Total CO2 CO2 mmol/l p to 1m m - 4y y - 9y >9y S rea mmol/l p to 2m m - 3y >3y Male >3y Female S Creatinine CR umol/l p to 1w w - 2w w - 3w w - 4w m - 3y y - 6y y - 10y y - 13y 40-80

2 13y - 15y Male Female 15-17y y y y >76y S egfr egfr ml/min/1.73m 2 Adult >90 Normal GFR Mild impairmaent with other evidence of chronic kidney damage Moderate impairment Severe impairment <15 Established renal failure Liver and Bone S Total Protein TP g/l p to 1m m - 6m m - 1y y - 11y >11y S Albumin ALB g/l p to 3m m - 3y y - 17y > 17y S Calcium CA mmol/l p to 1m & Corr Calcium 1m - 3y y - 17y Over 17y S Magnesium MG mmol/l p to 1w w - 2y > 2y /07/2010 S Phosphate PO4 mmol/l p to 1m

3 1m - 1y y - 2y y - 13y y - 16y >16y /07/2010 S Bilirubin (Total) BIL umol/l 2d <150 3d - 1w <170 1w - 2w <80 2w - 3w <50 3w-1m <30 >1m <17 S Alkaline Phosphatase ALP I/l p to 1m m - 4y Y - 10y Male Female 10-12y y y y y y y y >19y S Alanine Transaminase ALT I/l p to 2y <50 > 2y M <45 F <40 S Aspartate transaminase AST I/l p to 6m m - 4y y - 7y >7y <40 S Gamma Glutamyl transfe GT I/l p to 1m 0-200

4 1m - 4m >4m M <70 F <45 S Lactate Dehydrogenase LD I/l >18y < 270 Routine Serum P Glucose (fasting) GL mmol/l p to 2w > 2w S Osmolality OSM mmol/kg /07/2010 S Amylase AMY I/l <100 S Troponin T TNT ug/l Feb-09 < ndetectable Trop T indicates no myocardial injury. Assuming at least 12 hours post event >=0.010 Detectable Trop T indicates myocardial injury - consider MI or non-ischaemic troponin release depending on clinical picture S Iron FE umol/l Over 3y 9-28 S Transferrin TRF g/l >1m S Transferrin Saturation PSAT % <16Y M 16-55Y F 16-55Y All >55Y S Ferritin FER ug/l

5 S Cholesterol CHOL mmol/l See local guidelines for interpretation S Triglycerides (fasting) TRIG mmol/l <1.9 S HDL Cholesterol HDL mmol/l Male >1.0 Female >1.1 S Total/HDL Cholesterol ratio See local guidelines for interpretation S LDL Cholesterol LDL mmo/l/l See local guidelines for interpretation S rate RA mmol/l p to 1y > 1y M >1y F S Creatine Kinase (Total) CK I/l p to 1m < 850 1m - 2y < 350 2y - 17y < 250 >17y M < 190 F < 160 Endocrine S TSH TSH m/l >5d /03/10 S Free Thyroxine FT4B pmol/l >5d /03/10 S Free T3 FT3 pmol/l /03/10 S LH LH /l nder 12y < 6 Male >12y Follicular 2-10 Mid-Cycle Luteal 2-11 Post-Menop >30 Pregnant <2.0

6 Female > 55y >20 S FSH FSH /l nder 12y Male >12y Follicular 2-10 Mid-Cycle 5-28 Luteal 2-8 Post-Menop >30 Pregnant <2 Female > 55y >23 S Prolactin PROL m/l Males >17yrs <277 29/03/10 F (premen) <564 F (post men) <415 S Oestradiol E2 pmol/l M >12Y Follicular F > 55Y 145 Mid cycle F<55Y See Comment Luteal Post Menopause <145 S Progesterone PROG nmol/l Pre ovulation <5 Post Ovulation >20 S Testosterone TESTO nmol/l Male (>17Y) /03/10 Female (>17Y) <2.6 S Cortisol COR nmol/l 9am Cortisol reference range am S HCG HCG I/l M + F, <12y <2 M >12Y <5 F 12-55y <10 F, >55y <5 Tumour markers S AFP AFP k/l <7d <100, d <80,000

7 14d - 4w <30,000 5w - 9w <7,500 10w - 13w <750 14w - 17w <220 18w - 21w <150 22w - 26w <70 27w - 30w <25 31w - 35w <20 36w - 16y < y <10 S Prostate Specific Ag PSA ng/ml < < < and over 6.5 S Carcino Embryonic Ag CEA ug/l <5 S CA 19-9 CA199 /ml <34 S CA 125 CA125 k/l <35 S CA 15-3 CA153 k/l <51 TDM S Digoxin DIG ug/l S Paracetamol PARA mg/l S Salicylate SAL mg/l S Theophylline THEO mg/l S Carbamazepine CARB mg/l 4-12 S Phenytoin PHY mg/l 10-20

8 S Valproate VALP mg/l S Phenobarbitone PHENO mg/l S Lithium LI mmol/l Specific Proteins S α-1-acid Glycoprotein AGP g/l S C-Reactive Protein CRP mg/l <5 S IgG IGG g/l <13w None 14w - 26w w - 39w w - 51w y y y - 5y y - 14y y - 150y S IgA IGA g/l <13w None 14w - 26w w - 51w y y y y y y - 45y y - 150y S IgM IGM g/l <13w None 14w - 26w w - 39w w - 51w y - 2y

9 3y - 5y y - 11y y - 45y y - 150y Blood Gases B ph PH B pco2 PCO2 kpa p to 2y y - 150y B po2 kpa B Actual Bicarbonate ABIC mmol/l <2y y B Base Excess BXS mmol/l 4w y -7 >2y -3 to +3 B Standard Bicarbonate SBIC mmol/l <2y >2y B % O2 Saturation SAT % Metabolites P Plasma Lactate t LACT mmol/l < B Ammonia AMM umol/l 0-4w M F Misc Blood B HbA1c HBA1 % Non-diabetic subjects HbA1c < 6.1% HbA1c results DCCT aligned.

10 B Blood Alcohol mg/l Comment B Carboxyhaemoglobin COHB % <5.0 B Methaemoglobin METHB % <1.5 C CSF CSF Appearance C CSF Protein CTP g/l <0.4 C CSF Glucose CGL mmol/l C CSF Lactate CLACT mmol/l C CSF Bilirubin CBIL Abs units <0.007 F F F Faeces Faecal Occult Blood F Reducing Substances Faecal Porphyrins Fluid W Fluid Volume ml W Fluid Protein FTP g/l W Fluid Albumin FALB g/l W Fluid LDH FLD I/l W Fluid ph FPH W Fluid Amylase FAMY /l

11 W Fluid Sodium mmol/l W Fluid Potassium mmol/l W Fluid rea mmol/l W Fluid Creatinine umol/l W Fluid Osmolality mmol/kg W Fluid Lactate mmol/l W Fluid Bilirubin umol/l W Fluid Cholesterol mmol/l W Fluid Triglycerides mmol/l W Fluid Glucose mmol/l W Fluid CO2 mmol/l W Fluid CA19-9 /ml W Fluid CEA ug/l W Fluid Iron umol/l W Fluid AFP ug/l rine &E rine Volume ml rine Sodium mmol/l 24h rine Sodium NA24 mmol/24h

12 rine Potassium mmol/l 24h rine Potassium K24 mmol/24h rine rea mmol/l 24h rine rea 24 mmol/24h rine Creatinine mmol/l 24h rine Creatinine CR24 mmol/24h M F rine Chloride mmol/l 24h rine Chloride CL24 mmol/24h h Creat Clearance CRCL ml/min Adult Male Adult Female rine Osmolality OSM mmol/kg Misc rine rine Albumin (Microalbu ALB mg/l rine Albumin/Creatinine ACR mg/mmol Creat >16y rine Calcium mmol/24h rine Calcium/Creatinine CACR mmol/mmol creat 0-51w y y y - 4y y - 6y y - 17y y - 150y <0.70

13 24h rine Calcium CA24 mmol/24h rine Magnesium mmol/l rine Mg/Creat MGCR mmol/mmol creat 51w y y y y y y y >17y h rine Magnesium MG24 mmol/24h rine Phosphate mmol/l rine Phosphate/Creatini PO4CR mmol/mmol creat 26w - 51w y y y - 4y y - 6y y - 9y y - 13y y - 17y y - 150y <2.9 24h rine Phosphate PO424 mmol/24h rine Protein mg/l rine Protein/Creatinine r TPCR mg/mmol creat p to 1y 0-56

14 2y - 150y h rine Protein TP24 mg/24h <150 rine rate mmol/l rine rate/creatinine ra RACR mmol/mmol creat 7d w y y y y y y y >17y h rine rate RA24 mmol/24h rine ph i rine Hydroxy Indole Acetic Acid umol/l HIAA/Creatinine ratio HIACR umol/mmol creat <4 24h rine HIAA HIACR umol/24h robilin robilinogen Porphobilinogen rinary Bilirubin rinary Haemoglobin

15 Reducing Substances rine Glucose rine Alcohol mg/l Comment rine Ketones rine Amylase /l Amylase/Creat ratio Sweat SW Sweat Sodium SWNA mmol/l SW Sweat Chloride SWCL mmol/l <40 SW Sweat Rate SWRATE ul/30 minutes >15 Revisions Version Date Changes 2 04/11/2005 Added to Qpulse 3 17/02/2007 Reviewed 4 21/01/2008 Changes implemented 5 05/09/2008 Changes implemented 5 02/01/2009 Change to prolactin incorporated in version /01/2009 Change to prolactin incorporated in version /07/2009 Lithium ref range revised 8 13/04/2010 Change to DxI 9 05/07/2010 Network Harmonisation

Authorised: JSWoodford, Lead of Speciality. Biochemistry Reference Intervals, October Page 1 of 5

Authorised: JSWoodford, Lead of Speciality. Biochemistry Reference Intervals, October Page 1 of 5 AFP All All < 15 ug/l Albumin All 0-3M 25-40 g/l Albumin All 3-12M 32-45 g/l Albumin All 1-70Y 34-48 g/l Albumin All >70Y 32-46 g/l Alk Phos All 0-10Y 80-350 U/L Alk Phos M 10-14Y 45-400 U/L Alk Phos F