AGENDA for 11/18/13 AGENDA: HOMEWORK: Due end of period. Quiz on 2.1 on Fri, OBJECTIVES: 1. Finish 2.1.3: Feedback Diagraming Feedback Loops

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1 AGENDA for 11/18/13 AGENDA: 1. Finish 2.1.3: Feedback Diagraming Feedback Loops 2. Continue working on (see agenda for 11/15/13) OBJECTIVES: 1. Investigate feedback and feedback loops 2. Diagram the specific steps in the body that function to keep blood sugar in balance HOMEWORK: Due end of period Activity Packet (sub will collect) Quiz on 2.1 on Fri, Diabetes Diagnosis Type I vstype II Credibility and Reliability Glucose-Insulin Connection Feedback Loops (body regulation and blood glucose)

2 Activity Feedback

3 Essential Questions for What is diabetes? 2. How is glucose tolerance testing used to diagnose diabetes? 3. How does the development of Type 1 and Type 2 diabetes relate to how the body produces and uses insulin? 4. What is the relationship between insulin and glucose? 5. How does insulin assist with the movement of glucose into body cells? 6. What is homeostasis? 7. What does feedback refer to in the human body? 8. How does the body regulate the level of blood glucose?

4 2.1 Key Terms Glucagon Glucose Tolerance Test Homeostasis Hormone A protein hormone secreted by pancreatic endocrine cells that raises blood glucose levels; an antagonistic hormone to insulin. A test of the body s ability to metabolize glucose that involves the administration of a measured dose of glucose to the fasting stomach and the determination of blood glucose levels in the blood or urine at intervals thereafter and that is used especially to detect diabetes. The maintenance of relatively stable internal physiological conditions (as body temperature or the ph of blood) in higher animals under fluctuating environmental conditions. A product of living cells that circulates in blood and produces a specific, often stimulatory, effect on the activity of cells that are often far from the source of the hormone. Insulin Negative Feedback Positive Feedback Type 1 Diabetes Type 2 Diabetes A protein hormone secreted by the pancreas that is essential for the metabolism of carbohydrates and the regulation of glucose levels in the blood. A primary mechanism of homeostasis, whereby a change in a physiological variable that is being monitored triggers a response that counteracts the initial fluctuation. Feedback that tends to magnify a process or increase its output. Diabetes of a form that usually develops during childhood or adolescence and is characterized by a severe deficiency of insulin, leading to high blood glucose levels. Diabetes of a form that develops especially in adults and most often obese individuals and that is characterized by high blood glucose resulting from impaired insulin utilization coupled with the body s inability to compensate with increased insulin production.

5 Activity Objectives Investigate feedback and feedback loops 2. Diagram the specific steps in the body that function to keep blood sugar in balance

6 Conclusion Question 1. Is blood sugar regulated by negative or positive feedback? Explain your answer. 2. Explain how a problem with insulin receptors would affect the ability to achieve homeostasis. 3. Explain how it is possible that a problem with hormones and feedback led to Anna Garcia s untimely death. Due Thurs, 11-14

7 2.1.3 Activity Checklist Definitions (NB) STAMP Feedback Notes (NB) STAMP Feedback Diagrams (print-out) Regulation of Body Temperature STAMP Regulation of Blood Sugar (graded) 1. Completed Diagram 2. Correct order/descriptions 3. Picture/image for each box 4. State if each loop is a positive or negative feedback mechanism Total = 14

8 Activity Directions

9 Definitions (NB) 1. Watch the video by clicking on the following link: / html(if this link doesn t work, try the link on the class website) 1. Read the curriculum file for Define and give an detailed example (a picture helps) of the following (in your NB): Feedback Feedback mechanism

10 Feedback Notes (NB) 1. After some internet research, take notes about how the body uses feedback mechanisms to regulate body temperature. Mention: 1. Organs and tissues involved 2. Function of each organ/tissue in loop 2. After some internet research, take notes about how sugar enters the body and how the increase is controlled. Mention: 1. Glands involved 2. Hormones released 3. Response of target organs 3. After some internet research, take notes about how the body handles a drop in blood sugar. Mention: 1. Glucagon 2. Glands involved 3. Hormones released 4. Response of target organs

11 Feedback Diagrams (Inspiration print-out) 1. Read the curriculum file for Construct a feedback diagram for the regulation of body temperature. Include a picture in each box of the diagram. Follow the directions and the template in the curriculum file (steps 4-5). 3. Construct a feedback diagram for the regulation of blood sugar (insulin-glucagon feedback loop). Include a picture in each box of the diagram. Follow the directions and the template in the curriculum file (steps 10-12). 4. Print out both diagrams on 1 Word doc page. Print copies for you and your partner.

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