UNC Heart Failure Details

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1 UC Heart Failure Details File ame ID WHI Participant Common ID Col#1 CASEDY Days from enrollment to case date Col#2 7,096 40, , , Usage otes: CASEDY is known for each case that was selected to be sent to UC for adjudication. It is calculated as the days from enrollment to hospital admission for the case under review (same as ARRIVEDY). UCHF Definite or possible decompensated heart failure for this case Col#3 1 Yes 4, , Usage otes: UCHF = 1 if HFDIAG = 1 or 2. This is the standard WHI definition of heart failure using the UC adjudication. UCMISSIG Participant has a case that is missing documentation or not completed Col#4 1 Yes , Usage otes: This flag indicates that the participant has at least one case that either was not sent to UC for adjudication because it lacked sufficient documentation or WHI has not received the case back from UC. There are not separate records in this file for the missing cases since no UC form data exists. EDWHIDY Days enrollment to end of WHI core study followup Col#5 47, , Usage otes: EDWHIDY should only be used for analyses censoring follow-up at the end of the WHI core study. EDEXT1DY Days enrollment to end of Ext1 followup Col#6 47, , , Usage otes: EDEXT1DY should only be used for analyses censoring follow-up at the end of Ext1. EDFOLLOWDY Days enrollment to end of followup Col#7 47, , , Usage otes: EDFOLLOWDY should be used for analyses utilizing all WHI, Ext1 and Ext2 follow-up. F135DY F135 Days from enrollment to 135 completion Col#8 1c. Days from enrollment to 135 completion Page 1 of 41

2 UC Heart Failure Details File ame 7,098 40, , ABLVSYST F135 Abnormal LV systolic function Col#9 3a. Abnormal left ventricle systolic function? 0 o 2, Yes 2, Unknown 1, , ABRVSYST F135 Abnormal RV systolic function Col#10 3b. Abnormal right ventricle systolic function? 0 o 1, Yes Unknown 4, , LVDIASDYSF F135 LV diastolic dysfunction Col#11 3c. Left ventricle diastolic dysfunction 0 o Yes 1, Unknown 5, , ESTLVEF F135 Estimated LV ejection fraction Col#12 4. Estimated left ventricular ejection fraction (worst; related to current hospitalization) 1 50% or more 2, %-49% less than 35% Unknown 2, , HFDIAG F135 Heart failure diagnosis Col#13 5. Assign an overall heart failure diagnosis based on your clinical judgment 1 Definite decompensated heart failure 2, Possible decompensated heart failure 1, Chronic stable heart failure 1, Heart failure unlikely Unclassifiable , Usage otes: WHI considers the case to be a heart failure event when HFDIAG = 1 or 2. ADHFTYPE HF type for definite or probable decompensated heart failure Col#14 Page 2 of 41

3 UC Heart Failure Details File ame 1 Preserved ejection fraction acute 1, decompensated HF 2 Recovered ejection fraction acute decompensated HF 3 Systolic acute decompensated heart failure 1, , Usage otes: The definition for ADHFTYPE follows that of the ARIC study, and classifies the HF events as decompensated heart failure with preserved ejection fraction, systolic heart failure or recovered. DECOMP F135 Possible decompensated Col#15 5a. Was definite or possible decompensated heart failure present at admission? 0 o Yes 3, Unknown , FATAL F135 Fatal event Col#16 6. Was this event fatal? 0 o 4, Yes , DECOMPCOD F135 Decomp COD Col#17 6a. Was decompensated heart failure the primary cause of death? 0 o Yes Unknown , ARRIVEDY F136 Days from enrollment to hospital admission Col#18 0b. Days from enrollment to hospital admission 7,096 40, , , DSCHDY F136 Days from enrollment to hospital discharge Col#19 0c. Days from enrollment to hospital discharge (for nonfatal case) or death 7,063 40, , , ADMDIAGCODE F136 Primary admission diagnosis code Col#20 0d. What was the primary admitting diagnosis code? 3,012 44,497 Page 3 of 41

4 UC Heart Failure Details File ame DISCHDIAG F136 Discharge diagnosis code Col#21 0e. What was the primary discharge diagnosis code? 3,967 43,542 DISCHDISP F136 Discharge disposition Col#22 0f. What was the disposition of the patient on discharge? A Alive 6, D Deceased , AUTOPSY F136 Autopsy Done Col#23 0g. Was an autopsy performed? 0 o Yes , SHORTBRTHOSET F136 Shortness of breath at event onset Col#24 1a. Shortness of breath at event onset 0 o/ot Recorded 2, Yes 5, , EDEMAOSET F136 Edema at event onset Col#25 1b. Edema at event onset 0 o/ot Recorded 3, Yes 3, , OCTDYSPEAOS ET F136 Paroxysmal nocturnal dyspnea at event onset 1c. Paroxysmal nocturnal dyspnea at event onset 0 o / ot Recorded 6, Yes , Col#26 Page 4 of 41

5 UC Heart Failure Details File ame ORTHOPEAOSET F136 Orthopnea at event onset Col#27 1d. Orthopnea at event onset 0 o / ot Recorded 5, Yes 1, , HYPOXIAOSET F136 Hypoxia at event onset Col#28 1e. Hypoxia at event onset 0 o / ot Recorded 5, Yes 1, , DROTES F136 Doctors notes Col#29 2. Was there evidence in the doctor's notes that the reason for this hospitalization was heart failure? 0 o / ot Recorded 3, Yes 3, , SIGSADM F136 Signs/symptoms present at admission Col#30 3a. Signs/symptoms present at the time of admission to the hospital? 0 o / ot Recorded 1, Yes 5, , SIGSDURIG F136 Signs/symptoms present during hospitalization Col#31 3b. Signs/symptoms present during this hospitalization? 0 o / ot Recorded 1, Yes , SIGSDY F136 Days from enrollment to signs/symptoms known Col#32 4. Days from enrollment to signs/symptoms known 3,338 44, , , WEEKSPRIOR F136 Weeks prior signs/symptoms known Col#33 4a. If exact date of signs/symtoms unknown, estimate weeks prior to this hospitalization 1,850 45, Page 5 of 41

6 UC Heart Failure Details File ame ISCHMYOP F136 Ischemic cardiomyopathy Col#34 5a. Ischemic cardiomyopathy 0 o / ot Recorded 6, Yes , IDIOMYOP F136 Idiopathic/dilated cardiomyopathy Col#35 5b. Idiopathic/dilated cardiomyopathy 0 o / ot Recorded 6, Yes , MYOPOTH F136 Other specific cardiomyopathy Col#36 5c. Other specific cardiomyopathy/heart failure 0 o / ot Recorded 5, Yes 1, , DIASHF F136 Diastolic HF Col#37 5d1. Diastolic HF 0 o 5, Yes 1, , SYSTHF F136 Systolic HF Col#38 5d2. Systolic HF 0 o 6, Yes , RIGHTSIDEHF F136 Right-sided HF Col#39 5d3. Right-sided HF 0 o 6, Yes , Page 6 of 41

7 UC Heart Failure Details File ame IFILTRATHF F136 Infiltrative HF Col#40 5d4. Infiltrative HF 0 o 7, Yes , HYPERMYOP F136 Hypertrophic cardiomyopathy Col#41 5d5. Hypertrophic Cardiomyopathy 0 o 7, Yes , MYOCARDITIS F136 Myocarditis Col#42 5d6. Myocarditis 0 o 7, Yes , CARDMYOPOTH F136 Other cardiomyopathy Col#43 5d7. Other cardiomyopathy 0 o 6, Yes , CARDMYOPOTHSPE C F136 Other cardiomyopathy, specify 5d7a. Other cardiomyopathy, specify Col# ,975 PRIORDIAG F136 Prior diagnosis of heart failure Col#45 6a. Prior diagnosis of heart failure 0 o/ot Recorded 3, Yes 3, Unsure , Page 7 of 41

8 UC Heart Failure Details File ame PRIORHOSP F136 Prior hospitalization for HF Col#46 6b. Prior hospitalization for heart failure 0 o/ot Recorded 4, Yes 1, Unsure 1, , PRIORTREAT F136 Prior treatment for HF Col#47 6c. Prior treatment for heart failure 0 o/ot Recorded 4, Yes 1, Unsure 1, , CARDIMAG F136 Cardiac imaging Col#48 7. Was cardiac imaging performed prior to this hospitalization? 0 o/unknown 4, Yes 2, , LOWEJECTFRAC F136 Lowest ejection fraction, % Col#49 7a. Lowest Ejection Fraction recorded, % 1,843 45, QUALDESC F136 Qualitative description Col#50 7a1. Qualitative description 1 ormal Decreased mildly Decreased moderately Decreased severely one of the above Unsure-ot available , EJECTFRACYR F136 years from enrollment to lowest ejection fraction year Col#51 1,960 45, Page 8 of 41

9 UC Heart Failure Details File ame IMAGETYPE F136 Imaging type Col#52 7c. Type of Imaging 1 MUGA EHCO 1, Cath/LV gram CT MRI Myocardial Perfusion Imaging Other Unknown , ALCOHOLHX F136 History of excess alcohol use Col#53 8a. History of excess alcohol use 0 o/ot Recorded 6, Yes , ILLICITDRUGHX F136 History of illicit drug use Col#54 8b. History of illicit drug use 0 o/ot Recorded 7, Yes , AEMIAHX F136 History of anemia Col#55 8c. History of anemia 0 o/ot Recorded 5, Yes 1, , TISSUEDISHX F136 History of connective tissue disease Col#56 8d. History of connective tissue disease 0 o/ot Recorded 6, Yes , SMOKERHX F136 History of current smoker Col#57 8e. History of current smoker 0 o/ot Recorded 6, Yes , Page 9 of 41

10 UC Heart Failure Details File ame THYROIDDISHX F136 History of thyroid disease Col#58 8f. History of thyroid disease 0 o/ot Recorded 5, Yes 1, , ASTHMAHX F136 History of asthma Col#59 9a. History of asthma 0 o/ot Recorded 6, Yes , BROCHITISHX F136 History of chronic bronchitis/copd Col#60 9b. History of chronic bronchitis/copd 0 o/ot Recorded 5, Yes 1, , LUGOTHHX F136 History of other chronic lung disease Col#61 9c. History of other chronic lung disease 0 o/ot Recorded 6, Yes , PEHX F136 History of pulmonary embolus Col#62 9d. History of pulmonary embolus 0 o/ot Recorded 6, Yes , COUGHHX F136 History of coughing,phlegm,wheezing Col#63 9e. History of coughing, phlegm, wheezing 0 o/ot Recorded 6, Yes , Page 10 of 41

11 UC Heart Failure Details File ame SLEEPAPEAHX F136 History of sleep apnea Col#64 9f. History of sleep apnea 0 o/ot Recorded 6, Yes , AGIAHX F136 History of angina Col#65 10a. History of angina 0 o/ot Recorded 6, Yes 1, , AFIBHX F136 History of atrial fibrillation/flutter Col#66 10b1. History of atrial fibrillation/atrial flutter 0 o/ot Recorded 4, Yes 2, , HEARTBLOCKHX F136 History of heart block or other severe bradycardia Col#67 10b2. History of heart block or other severe bradycardia 0 o/ot Recorded 6, Yes , VEFIBHX F136 History of ventricular fibrillation or tachycardia Col#68 10b3. History of ventricular fibrillation or tachycardia 0 o/ot Recorded 6, Yes , CABGHX F136 History of CABG Col#69 10C1. History of CABG 0 o/ot Recorded 6, Yes , Page 11 of 41

12 UC Heart Failure Details File ame PCIHX F136 History of PCI Col#70 10c2. History of PCI 0 o/ot Recorded 6, Yes , VALVSURGHX F136 History of valve surgery Col#71 10c3. History of valve surgery 0 o/ot Recorded 6, Yes , PACEMKRHX F136 History of pacemaker Col#72 10c4. History of pacemaker 0 o/ot Recorded 6, Yes , DEFIBHX F136 History of defibrillator Col#73 10c5. History of defibrillator 0 o/ot Recorded 6, Yes , CHDYRHX F136 History of CHD within 1 year Col#74 10d. History of Coronary heart disease (within 1 year) 0 o/ot Recorded 6, Yes , CHDEVERHX F136 History of CHD ever Col#75 10e. History of coronary heart disease (ever) 0 o/ot Recorded 4, Yes 2, , Page 12 of 41

13 UC Heart Failure Details File ame HYPERTHX F136 History of hypertension Col#76 10f. History of hypertension 0 o/ot Recorded 1, Yes 5, , MIHX F136 History of MI Col#77 10g. History of myocardial infarction 0 o/ot Recorded 5, Yes 1, , PULMHTHX F136 History of pulmonary hypertension Col#78 10h. History of pulmonary hypertension 0 o/ot Recorded 6, Yes , PVDHX F136 History of peripheral vascular disease Col#79 10i. History of peripheral vascular disease 0 o/ot Recorded 6, Yes , VALVHDHX F136 History of valvular heart disease Col#80 10j. History of valvular heart disease 0 o/ot Recorded 5, Yes 1, , DIABHX F136 History of diabetes Col#81 11a. History of diabetes 0 o/ot Recorded 4, Yes 2, , Page 13 of 41

14 UC Heart Failure Details File ame DIALYSISHX F136 History of dialysis Col#82 12a. History of dialysis 0 o/ot Recorded 6, Yes , STROKEHX F136 History of stroke/tia Col#83 13a. History of stroke/tia 0 o/ot Recorded 5, Yes 1, , DEPRESSHX F136 History of depression Col#84 13b. History of depression 0 o/ot Recorded 6, Yes , PRECIPMI F136 Angina or MI precipating factor Col# Was angina or myocardial infarction listed as a precipitating factor (i.e. precipitated the onset of this event)? 0 o/ot Recorded 5, Yes 1, , SYST F136 Systolic blood pressure at onset, mm/hg Col#86 15a. Blood pressure at onset or hospital admission: systolic, mm/hg 6,419 41, DIAS F136 Diastolic blood pressure at onset, mm/hg Col#87 15b. Blood pressure at onset or hospital admission:diastolic, mm/hg 6,376 41, HEARTRATE F136 Heart rate at onset, bpm Col#88 16a. Heart rate at onset or hospital adission, bpm 6,314 41, HEIGHT F136 Height, cm Col#89 17a. Height, cm Page 14 of 41

15 UC Heart Failure Details File ame 2,681 44, WEIGHTADM F136 Weight at onset, kg Col#90 18a. Weight at onset or hospital admission, kg 3,361 44, WEIGHTDSCH F136 Weight, last recorded, kg Col#91 18b. Weight at hospital discharge or last recorded, kg 1,757 45, LOWEXEDEMA F136 Lower extremety edema Col#92 19a. Lower extremity edema during hospitalization or at admission 0 o/ot Recorded 3, Yes 3, , JVD F136 Jugular venous distension Col#93 19b. Jugular venous distension (JVD) during hospitalization or at admission 0 o/ot Recorded 5, Yes 1, , HEPREFLUX F136 Hepatojugular reflux Col#94 19c. Hepatojugular reflux during hospitalization or at admission 0 o/ot Recorded 7, Yes , HEPATOMEGALY F136 Hepatomegaly Col#95 19d. Hepatomegaly during hospitalization or at admission 0 o/ot Recorded 7, Yes , Page 15 of 41

16 UC Heart Failure Details File ame LEGFATIGUE F136 Leg fatigue Col#96 19e. Leg fatigue on walking during hospitalization or at admission 0 o/ot Recorded 7, Yes , COUGH F136 Cough Col#97 20a. Cough during hospitalization or at admission 0 o/ot Recorded 5, Yes 1, , DYSPEAREST F136 Dyspnea at rest Col#98 20b. Dyspnea (Rest) (If yes, enter yes for 20c, 20d, 20e, 20f.) during hospitalization or at admission 0 o/ot Recorded 2, Yes 4, , DYSPEAWLK F136 Dyspnea while walking Col#99 20c. Dyspnea (while walking) during hospitalization or at admission 0 o/ot Recorded 2, Yes , DYSPEACLIMB F136 Dyspnea while climbing Col#100 20d. Dyspnea (Climbing or exertion) during hospitalization or at admission 0 o/ot Recorded 2, Yes , BREATHWLK F136 Stops for breath when walking Col#101 20e. Stops for breath when walking during hospitalization or at admission 0 o/ot Recorded 2, Yes , Page 16 of 41

17 UC Heart Failure Details File ame BREATH100 F136 Stops for breath after 100 yards Col#102 20f. Stops for breath after 100 yards during hospitalization or at admission 0 o/ot Recorded 2, Yes , RHOCHI F136 Rhonchi Col#103 20g. Rhonchi during hospitalization or at admission 0 o/ot Recorded 6, Yes , OCTDYSPEA F136 Paroxysmal nocturnal dyspnea Col#104 20h. Paroxysmal nocturnal dyspnea during hospitalization or at admission 0 o/ot Recorded 6, Yes , ORTHOPEA F136 Orthopnea Col#105 20i. Orthopnea during hospitalization or at admission 0 o/ot Recorded 5, Yes 1, , PULMBASRALES F136 Pulmonary basilar rales Col#106 20j. Pulmonary basilar rales during hospitalization or at admission 0 o/ot Recorded 5, Yes 1, , RALES F136 Rales Col#107 20k. Rales (more than basilar) during hospitalization or at admission 0 o/ot Recorded 4, Yes 1, , Page 17 of 41

18 UC Heart Failure Details File ame WHEEZIG F136 Wheezing Col#108 20l. Wheezing during hospitalization or at admission 0 o/ot Recorded 5, Yes 1, , HYPOXIA F136 Hypoxia Col#109 20m. Hypoxia during hospitalization or at admission 0 o/ot Recorded 5, Yes 2, , S3GALLOP F136 S3 gallop Col#110 21a. S3 gallop during hospitalization or at admission 0 o/ot Recorded 6, Yes , S4GALLOP F136 S4 gallop Col#111 21b. S4 gallop during hospitalization or at admission 0 o/ot Recorded 6, Yes , MURMUR F136 Murmur Col#112 21c. Murmur during hospitalization or at admission 0 o/ot Recorded 5, Yes 1, , CHESTPAI F136 Chest pain Col#113 21d. Chest Pain during hospitalization or at admission 0 o/ot Recorded 5, Yes 2, , Page 18 of 41

19 UC Heart Failure Details File ame CHESTXRAY F136 Chest xray Col# Was a chest X-ray performed during this hospitalization? 0 o/ot Recorded 1, Yes 6, , ALVEOLAREDEMA F136 Alveolar/pulmonary edema Col#115 23a. Alveolar/pulmonary edema 0 o/unknown 4, Yes 1, , ITEREDEMA F136 Interstitial pulmonary edema Col#116 23b. Interstitial pulmonary edema 0 o/unknown 4, Yes 1, , CARDIOMEGALY F136 Cardiomegaly Col#117 23c. Cardiomegaly 0 o/unknown 2, Yes 3, , CEPHALIZATIO F136 Cephalization Col#118 23d. Cephalization/upper zone redistribution 0 o/unknown 5, Yes , BIPLEUEFF F136 Bilateral pleural effusion Col#119 23e. Bilateral pleural effusion 0 o/unknown 4, Yes 1, , Page 19 of 41

20 UC Heart Failure Details File ame UIPLEUEFF F136 Unilateral pleural effusion Col#120 23f. Unilateral pleural effusion 0 o/unknown 3, Yes , CARDRATIO F136 Cardiothoracic ratio >= 0.5 Col#121 23g. Cardiothoracic ratio greater than or equal to o/unknown 6, Yes , CHFPVD F136 CHFPVD Col#122 23h. Congestive heart failure/pulmonary vascular congestion 0 o/unknown 2, Yes 3, , TTE F136 Transthoracic echocardiogram (TTE) Col# Was a transthoracic echocardiogram (TTE) performed? 0 o/ot Recorded 3, Yes 3, , TTEDY F136 Days from enrollment to TTE Col#124 24a. Days from enrollment to TTE 3,349 44, , , TTEEJECT F136 TTE ejection fraction, % Col#125 24b. TTE ejection fraction, % 3,326 44, TTESEPTAL F136 TTE septal LV wall thickness Col#126 24c. TTE septal LV wall thickness 2,334 45, TTESEPUITS F136 TTE septal LV wall thickness units Col#127 24c1. TTE spetal LV wall thickness units Page 20 of 41

21 UC Heart Failure Details File ame 1 cm 1, mm , TTEPOST F136 TTE posterior LV wall thickness Col#128 24c2. TTE posterior LV wall thickenss 2,304 45, TTEPOSTUITS F136 TTE posterior LV wall thickness units Col#129 24c3. TTE posterior LV wall thickness units 1 cm 1, mm , TTELVH F136 TTE LVH Col#130 24d1. Left ventricular hypertrophy (LVH) 1 Mild Moderate Severe one Present ot Recorded 1, , TTEIMPLVSYST F136 TTE impaired LV systolic function Col#131 24d2. Impaired LV systolic function 1 Mild Moderate Severe one 1, Present ot Recorded , TTEIMPLVDIAS F136 TTE impaired LV diastolic function Col#132 24d3. Impaired LV diastolic function 1 Mild Moderate Severe one Present ot Recorded 2, , Page 21 of 41

22 UC Heart Failure Details File ame TTEIMPRVSYST F136 TTE impaired RV systolic function Col#133 24d4. Impaired RV systolic function 1 Mild Moderate Severe one 1, Present ot Recorded 1, , TTEAORTICREGURG F136 TTE aortic regurgitation Col#134 24d5. Aortic regurgitation 1 Mild Moderate Severe one 1, Present ot Recorded 1, , TTEAORTICSTE F136 TTE aortic stenosis Col#135 24d6. Aortic stenosis 1 Mild Moderate Moderate one 2, Present ot Recorded 1, , TTETRICUSPIDREGU RG F136 TTE tricuspid regurgitation Col#136 24d7. Tricuspid regurgitation 1 Mild 1, Moderate Severe one Present ot Recorded , Page 22 of 41

23 UC Heart Failure Details File ame TTEMITRALREGURG F136 TTE mitral regurgitation Col#137 24d8. Mitral regurgitation 1 Mild 1, Mild Severe one Present ot Recorded , TTEMITRALSTE F136 TTE mitral stenosis Col#138 24d9. Mitral stenosis 1 Mild Moderate Severe one 2, Present ot Recorded 1, , TTEESTRVSP F136 TTE estimated RVSP, mm/hg Col#139 24d10. Estimated RVSP, mm/hg 2,115 45, TTETRVELOM F136 TTE RVSP TR jet velocity, m/sec Col#140 24d10a. RVSP TR jet velocity, m/sec , TTETRVELOCM F136 TTE RVSP TR jet velocity, cm/sec Col#141 24d10b. RVSP TR jet velocity, cm/sec , TTEPULMHT F136 TTE pulmonary hypertension Col#142 24d11. Pulmonary Hypertension 1 Mild Moderate Severe one Present ot Recorded 2, , Page 23 of 41

24 UC Heart Failure Details File ame TTEWALLAB F136 TTE regional wall motion abnormality Col#143 24d12. Regional wall motion abnormality 0 o 1, Yes 1, Unknown/ot Recorded 1, , TTEDILLVET F136 TTE dilated left ventricle Col#144 24d13. Dilated left ventricle 0 o 2, Yes Unknown/ot Recorded 1, , TTEDILRVET F136 TTE dilated right ventricle Col#145 24d14. Dilated right ventricle 0 o 1, Yes Unknown/ot Recorded 1, , TEE F136 Transesophageal echocardiogram (TEE) Col# Was a transesophageal echocardiogram (TEE) performed? 0 o/ot Recorded 6, Yes , TEEDY F136 Days from enrollment to TEE Col#147 25a. Days from enrollment to TEE , , , TEEEJECT F136 TEE ejection fraction, % Col#148 25b. TEE ejection fraction, % , Page 24 of 41

25 UC Heart Failure Details File ame TEEIMPLVSYST F136 TEE impaired LV systolic function Col#149 25c1. TEE impaired LV systolic function 1 Mild Moderate Severe one Present ot Recorded , TEEIMPRVSYST F136 TEE impaired RV systolic function Col#150 25c2. TEE impaired RV systolic function 1 Mild Moderate Severe one Present ot Recorded , TEELAATHROMB F136 TEE left atrial appendage thrombus Col#151 25c3. TEE left atrial appendage (LAA) thrombus 0 o Yes Unknown/ot Recorded , TEEREGAB F136 TEE regional wall motion abnormailty Col#152 25c4. TEE regional wall motion abnormality 0 o Yes Unknown/ot Recorded , TEEDILLVET F136 TEE dilated left ventricle Col#153 25c5. TEE dilated left ventricle 0 o Yes Unknown/ot Recorded , Page 25 of 41

26 UC Heart Failure Details File ame TEEDILRVET F136 TEE dilated right ventricle Col#154 25c6. TEE dilated right ventricle 0 o Yes Unknown/ot Recorded , RCATH F136 Right cardiac catheterization Col# Was a right cardiac catheterization performed? 0 o/ot Recorded 6, Yes , RCATHDY F136 Days from enrollment to right cardiac catheterization Col#156 26a. Days from enrollment to right cardiac catheterization , , , RATRIAPRESS F136 Right atrial mean pressure Col#157 26b. Right atrial mean pressure , RVETSYST F136 Right ventricular systolic pressure Col#158 26c. Right ventricular systolic pressure , RVETDIAS F136 Right ventricular diastolic pressure Col#159 26d. Right ventricular diastolic pressure , PULMSYST F136 Pulmonary artery systolic pressure Col#160 26e. Pulmonary artery systolic pressure , PULMDIAS F136 Pulmonary artery diastolic pressure Col#161 26f. Pulmonary artery diastolic pressure , Page 26 of 41

27 UC Heart Failure Details File ame PULMWEDGEPRESS F136 Pulmonary capillary wedge pressure mean Col#162 26g. Pulmonary capillary wedge pressure mean , COROAGIO F136 Coronary agiography Col# Was coronary angiography performed? 0 o/ot Recorded 5, Yes 1, , COROAGIODY F136 Days from enrollment to coronary angiography Col#164 27a. Days from enrollment to coronary angiography 1,140 46, , , COROAGIOEJECT F136 Coronary angiography ejection fraction, % Col#165 27b1. Coronary antiography ejection fraction, % , COROAGIOLVET SYST F136 Coronary angiography left ventricular systolic pressure 27b2. Coronary left ventricular systolic pressure Col# , COROAGIOLVET DIAS F136 Coronary angiography left ventricular end diastolic pressure 27b3. Coronary left ventricular end diastolic pressure Col# , COROSTELMAI F136 Coronary stenosis left main Col#168 27b4a. Coronary stenosis left main 1 0% % % % % % % ot Recorded , Page 27 of 41

28 UC Heart Failure Details File ame COROSTELATAR T F136 Coronary stenosis left anterior artery 27b4b. Coronary stenosis left anterior descending artery and branches 1 0% % % % % % % ot Recorded , Col#169 COROSTELCIRCAR T F136 Coronary stenosis left circumflex/marginal artery Col#170 27b4c. Coronary stenosis left circumflex/marginal artery 1 0% % % % % % % ot Recorded , COROSTERCOROA RT F136 Coronary stenosis right coronary artery and branches Col#171 27b4d. Coronary stenosis right coronary artery and branches 1 0% % % % % % % ot Recorded , Page 28 of 41

29 UC Heart Failure Details File ame COROSTEITERM RAMUS F136 Coronary stenosis intermediate ramus 27b4e. Coronary stenosis intermediate ramus 1 0% % % % % % % ot Recorded 1, , Col#172 COROBYPASS F136 Coronary bypass grafts Col#173 27b5. Were coronary bypass grafts present? 0 o/ot Recorded 1, Yes , OCCLGRAFTS F136 umber of coronary bypass occluded grafts Col#174 27b5a. umber of occluded grafts , CARDRADVET F136 Cardiac radionuclide ventriculogram Col# Was a cardiac radionuclide ventriculogram performed? 0 o/ot Recorded 7, Yes , CARDRADVETDY F136 Days from enrollment to cardiac radionuclide ventriculogram Col#176 28a. Days from enrollment to cardiac radionuclide ventriculogram 34 47, , , CARDRADVETEJEC T F136 Cardiac radionuclide ventriculogram ejection fraction LV, % Col#177 28b. Cardiac radionuclide ventriculogram ejection fraction: LV, % 33 47, CARDRADVETRV F136 Cardio radionuclide ventriculogram RV, % Col#178 28c. Cardio radionnuclide ventriculogram RV, % Page 29 of 41

30 UC Heart Failure Details File ame 5 47, CARDMRI F136 Cardiac MRI Col# Was a cardiac Magnetic Resonance Imaging (MRI) performed? 0 o/ot Recorded 7, Yes , CARDMRIDY F136 Days from enrollment to cardiac MRI Col#180 29a. Days from enrollment to cardiac MRI 8 47, , , CARDMRIEJECT F136 Cardiac MRI ejection fraction LV, % Col#181 29b. Cardiac MRI ejection fraction LV, % 7 47, CARDMRIRV F136 Cardiac MRI RV, % Col#182 29c. Cardiac MRI RV, % 2 47, CARDCT F136 Cardiac CT Col# Was a cardiac CT scan performed? 0 o/ot Recorded 7, Yes , CARDCTDY F136 Days from enrollment to cardiac CT Col#184 30a. Days form enrollment to cardiac CT 7 47, , , CARDCTEJECT F136 Cardiac CT ejection fraction LV, % Col#185 30b. Cardiac CT ejection fraction: LV, % 0 CARDCTRV F136 Cardiac CT RV, % Col#186 30c. Cardiac CT RV, % Page 30 of 41

31 UC Heart Failure Details File ame 0 STRESSTEST F136 Stress test Col# Was a stress test performed? 0 o/ot Recorded 6, Yes , STRESSTESTDY F136 Days from enrollment to stress test Col#188 31a. Days from enrollment to stress test , , , STRESSTESTEJECT F136 Stress test ejection fraction LV, % Col#189 31b. Stress test ejection fraction LV, % , STRESSTESTRV F136 Stress test RV, % Col#190 31c. Stress test RV, % 1 47, CARDIMGOTH F136 Other cardiac imaging Col# Any other cardiac imaging? 0 o/ot Recorded 7, Yes , CARDIMGOTHSPEC F136 Other cardiac imaging specify Col# Any other cardiac imaging (specify)? 64 47,445 CARDIMGOTHDY F136 Days from enrollment to other cardiac imaging Col#193 32b. Days from enrollment to other cardiac imaging 54 47, , , CARDIMGOTHEJECT F136 Other cardiac imaging ejection fraction LV, % Col#194 32c. Other cardiac imaging ejection fraction LV, % Page 31 of 41

32 UC Heart Failure Details File ame 38 47, CARDIMGOTHRV F136 Other cardiac imaging RV, % Col#195 32d. Other cardiac imaging RV, % 2 47, BPWORST F136 BP worst, pg/ml Col#196 33a. BP worst, pg/ml 2,676 44, , , BPLAST F136 BP last, pg/ml Col#197 33b. BP last, pg/ml 2,607 44, , , BPUL F136 BP Upper limit normal, pg/ml Col#198 33c. BP upper limit normal, pg/ml 1,957 45, PROBPWORST F136 ProBP Worst, pg/ml Col#199 34a. ProBP worst, pg/ml , , , PROBPLAST F136 ProBP Last, pg/ml Col#200 34b. ProBP last, pg/ml , , , PROBPUL F136 ProBP Upper limit normal, pg/ml Col#201 34c. ProBP upper limit normal, pg/ml , , TROPWORST F136 Troponin/cardiac enzymes worst less than Col#202 35a. Troponin/cardiac enzymes worst less than 0 o 2, Yes 1, , Page 32 of 41

33 UC Heart Failure Details File ame TROPWORSTVAL F136 Troponin/cardiac enzymes worst value Col#203 35a1. Troponin/cardiac enzymes worst value 4,767 42, TROPUL F136 Troponin/cardiac enzymes upper limit normal less than Col#204 35b. Troponin/cardiac enzymes upper limit normal less than 0 o 2, Yes 1, , TROPULVAL F136 Troponin/cardiac enzymes upper limit normal value Col#205 35b1. Troponin/cardiac enzymes upper limit normal value 3,733 43, TROPTYPE F136 Troponin type Col#206 35c. If troponin value available, then what type of Troponin was this? 1 1. Troponin, type not specified Troponin I 3, Troponin T High Sensitivity Troponin (HS) ot recorded , CARDBIOOTH F136 Other cardiac biomarkers Col#207 35d. Other cardiac biomarkers measured 0 o 1, Yes 3, , SODIUM F136 Sodium, meq/l Col# Sodium, meq/l, worst value 5,935 41, SERUMCREAT F136 Serum creatinine, mg/dl Col# Serum creatinine, mg/dl, worst value 6,223 41, BU F136 BU, mg/dl Col#210 Page 33 of 41

34 UC Heart Failure Details File ame 38. BU, mg/dl, worst value 6,163 41, HEMOGLOBI F136 Hemoglobin, g/dl Col# Hemoglobin, g/dl, worst value 5,888 41, HEMATOCRIT F136 Hematocrit, % Col# Hematocrit, %, worst value 5,817 41, CARDDEFIB F136 Cardioversion or defibrillation Col#213 41a. Cardioversion or defibrillation 0 o/ot Recorded 6, Yes , ABLATIO F136 Ablation for atrial fibrillation Col#214 41b. Ablation for atrial fibrillation 0 o/ot Recorded 7, Yes , AORTICBALLOO F136 Aortic balloon pump Col#215 41c. Aortic balloon pump 0 o/ot Recorded 7, Yes , PCI F136 PCI Col#216 41d. Percutaneous coronary intervention (PCI) 0 o/ot Recorded 6, Yes , Page 34 of 41

35 UC Heart Failure Details File ame CPAPBIPAP F136 CPAP or BIPAP Col#217 41e. CPAP or BIPAP 0 o/ot Recorded 6, Yes , MECHVET F136 Mechanical ventilation Col#218 41f. Mechanical ventilation 0 o/ot Recorded 6, Yes , THORACET F136 Thoracentesis Col#219 41g. Thoracentesis (therapeutic or diagnostic) 0 o/ot Recorded 6, Yes , VAD F136 VAD Col#220 41h. Ventricular assist device (VAD) 0 o/ot Recorded 7, Yes , HEARTTRAS F136 Heart transplant Col#221 41i. Heart transplant 0 o/ot Recorded 7, Yes , ICUADM F136 ICU/CCU admission Col#222 41j. Cardiac ICU/CCU admission at any point during this hospital stay 0 o/ot Recorded 5, Yes 1, , Page 35 of 41

36 UC Heart Failure Details File ame ACEIHIBPRIOR F136 ACE Inhibitors prior Col# ACE Inhibitors prior to hospital or progression in hospital 0 o/ot Recorded 4, Yes 2, , ACEIHIBDSCH F136 ACE inhibitors discharge Col#224 42a. ACE inhibitors at hospital discharge 0 o/ot Recorded 4, Yes 2, , AGIOTESIPRIOR F136 Angiotensin II receptor blockers prior Col# Angiotensin II receptor blockers prior to hospital or progression in hospital 0 o/ot Recorded 6, Yes 1, , AGIOTESIDSCH F136 Angiotensin II receptor blockers discharge Col#226 43a. Angiotensin II receptor blockers at hospital discharge 0 o/ot Reported 6, Yes , BETABPRIOR F136 Beta blockers prior Col# Beta blockers prior to hospital or progession in hospital 0 o/ot Recorded 3, Yes 3, , BETABDSCH F136 Beta blockers discharge Col#228 44a. Beta blockers at hospital discharge 0 o/ot Recorded 3, Yes 3, , Page 36 of 41

37 UC Heart Failure Details File ame DIGITALISPRIOR F136 Digitalis prior Col# Digitalis prior to hospital or progression in hospital 0 o/ot Recorded 6, Yes , DIGITALISDSCH F136 Digitalis discharge Col#230 45a. Digitalis at hospital discharge 0 o/ot Recorded 6, Yes , DIURETICPRIOR F136 Diuretics prior Col# Diuretics prior to hospital or progression in hospital 0 o/ot Recorded 3, Yes 3, , DIURETICDSCH F136 Diuretics discharge Col#232 46a. Diuretics at hospital discharge 0 o/ot Recorded 3, Yes 3, , ALDOSTPRIOR F136 Aldosterone blocker prior Col# Aldosterone blocker prior to hospital or progression in hospital 0 o/ot Recorded 6, Yes , ALDOSTDSCH F136 Aldosterone blocker discharge Col#234 47a. Aldosterone blocker at hospital discharge 0 o/ot Recorded 6, Yes , Page 37 of 41

38 UC Heart Failure Details File ame STATIPRIOR F136 Statins prior Col#235 48a. Statins prior to hospital or progression in hospital 0 o/ot Recorded 4, Yes 2, , STATIDSCH F136 Statins discharge Col#236 48a1. Statins at hospital discharge 0 o/ot Recorded 4, Yes 2, , LIPIDOTHPRIOR F136 Other lipid lowering agents prior Col#237 48b. Other lipid lowering agents prior to hospital or progression in hospital 0 o/ot Recorded 6, Yes , LIPIDOTHDSCH F136 Other lipid lowering agents discharge Col#238 48b1. Other lipid lowering agents at hospital discharge 0 o/ot Recorded 6, Yes , ITRATESPRIOR F136 itrates prior Col# itrates prior to hospital or progression in hospital 0 o/ot Recorded 5, Yes 1, , ITRATESDSCH F136 itrates discharge Col#240 49a. itrates at hospital discharge 0 o/ot Recorded 5, Yes 1, , Page 38 of 41

39 UC Heart Failure Details File ame HYDRALAZIEPRIO R F136 Hydralazine prior 50. Hydralazine prior to hospital or progression in hospital 0 o/ot Recorded 6, Yes , Col#241 HYDRALAZIEDSCH F136 Hydralazine discharge Col#242 50a. Hydralazine at hospital discharge 0 o/ot Recorded 6, Yes , IVIOTROP F136 IV Inotropes Col#243 51a. IV Inotropes 0 o/ot Recorded 6, Yes , IVDIURETICS F136 IV Diuretics Col#244 51b. IV Diuretics 0 o/ot Recorded 3, Yes 3, , AFIB F136 Atrial fibrillation Col# Atrial fibrillation (A-Fib) present during this hospitalization 0 o/ot Recorded 5, Yes 1, , TAA F136 Thoracic aortic aneurysm/dissection Col# Thoracic aortic aneurysm/dissection present during this hospitalization 0 o/ot Recorded 7, Yes , Page 39 of 41

40 UC Heart Failure Details File ame AAA F136 Abdominal Aortic Aneurism Col# Abdominal aortic aneurysm present during this hospitalization 0 o/ot Recorded 7, Yes , CAD F136 Carotid artery disease Col# Carotid artery disease present during this hospitalization 0 o/ot Recorded 6, Yes , CABG F136 CABG Col# Coronary artery bypass graft (CABG) present during this hospitalization 0 o/ot Recorded 6, Yes , PTCA F136 PTCA Col# Percutaneous transluminal coronary angioplasty (PTCA), PCI, stent present during this hospitalization 0 o/ot Recorded 6, Yes , DVT F136 DVT Col# Deep vein thrombosis (DVT) present during this hospitalization 0 o/ot Recorded 6, Yes , MI F136 MI Col# Myocardial infarction (MI) present during this hospitalization 0 o/ot Recorded 6, Yes , Page 40 of 41

41 UC Heart Failure Details File ame PE F136 Pulmonary embolism Col# Pulmonary embolism (PE) present during this hospitalization 0 o/ot Recorded 6, Yes , PAD F136 Peripheral arterial disease Col# Peripheral arterial disease (PAD) present during this hospitalization 0 o/ot Recorded 7, Yes , STROKE F136 Stroke Col# Stroke/TIA present during this hospitalization 0 o/ot Recorded 6, Yes , HVD F136 Heart valve disease Col# Heart valve disease present during this hospitalization 0 o/ot Recorded 6, Yes , AYCACER F136 Any Cancer Col# Cancer, any site present during this hospitalization 0 o/ot Recorded 6, Yes , HIPFRAC F136 Hip/upper leg fracture Col# Hip/Upper leg (femur) fracture present during this hospitalization 0 o/ot Recorded 6, Yes , F136DY F136 Days from enrollment to 136 completion Col# Days from enrollment to 136 completion 6,948 40, , Page 41 of 41

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