Growth hormone is the master hormone responsible for directly and indirectly overseeing the production of all hormones in the

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1 At HGH Researc Laboratories, our goal is to gently influence physiological balance or homeostasis, rather than force a temporary change that may seem desirable at the onset, but may eventually result in imbalance. HGH Analog is biologically activated hybrid Somatotropin B captured and sustained in a complex polymer matrix that preserves and delivers the molecule into the body through the oral mucosa. The result is a powerful physiological response and feedback communication I to the pituitary gland, stimulating a gradual and gentle increase in growth hormone production. Previously, GH was on 1 y available through intra-muscular injections due to its size and instability. Now, through revolutionary technology, HGH Analog is available in an oral microdilution spray, safe and effective for general supplementation. Growth hormone is the master hormone responsible for directly and indirectly overseeing the production of all hormones in the body. Produced by the ant rior gland, the five main functions of GH are: 1. Transporting of amino acids across cell membranes Within four months, my body fat decreased from 30% down to 21%. I noticed that my skin seems to feel more supple. In addition, my overall mental outlook improved significant/y Transcribing DNA to form RNA, provided all essential nutrients are available Promoting protein synthesis in cytoplasm Reducing tissue breakdown of amino acids and protein by mobilizing large amounts of free fatty acids from adipose tissue Controlling blood sugar utilization D.W. New Jersey "... I have experienced a greater sense of wellbeing and peace since starting on HGH Analog. My energy level has improved dramatically. "... I.H. Acupuncturist

2 ORAL ABSORPTION: KNOW THE FACTS For years, scientists have been trying to develop an effective oral delivery method for growth hormone, but have been unsuccessful due to the molecule s large size and instability. I Now, with HGH Research Laboratories polymer matrix delivery system, safe, effective oral HGH Analog supplementation is finally possible. Without this revolutionary technology, GH taken orally is essentially broken down into simple amino acids, losing its unique physiological properties. But with polymer matrix technology, HGH Analog is successfully preserved, encapsulated, and delivered into the body through the oral mucosa. I immediately experienced improved sleep patterns and more vivid dreaming. I found that I required less sleep and had more energy throughout the day." _ Andrew W., San Diego HISTORY OF ORAL GH HGH Analog creator and formulator, Dr. Roy Dittman, has always had a fascination with growth factors. As early as age 11, he began experimenting with plant growth using giberillic acid. Giberillins are the functional equivalent to growth hormone in plants. In the 1980 s Dr. Dittman studied privately with microbiologists to understand the evolution of life forms via micro-organisms, and researched the impact of hormones on early human brain development. Starting in 1984, Dr. Dittman began his work to determine safe and effective methods of evolving the human brain in the period from preconception to the first three years of life. In 1988, he formulated the first somato-sensory sound stimulation protocol for the fetal brain. In 1992, he co-founded The Leonardo Foundation with Dr. Thomas Blum, neuro-physiology professor, Benin, Germany. Their goal was to combine science with natural methods to enhance early human brain development, and as a result of this collaboration, The Leonardo Foundation published two technical books on early human psycho-physiology. From 1992 to 1996, Dr. Dittman researched oral absorption technologies. Consulting with some of the world s leading experts on advanced oral absorption of large protein molecules and dietary supplements, he began writing a book on oral absorption. During the same time period, he theorized that IGF-2, regulated by growth hormone, was responsible for the enhancement of cognitive abilities in developing fetuses. This theory, later confirmed by Science Magazine (May, 1998) combined with his research on oral absorption led him to develop a safe, effective micro-dilution oral hybrid Somatotropin-B supplement. After three years of research on oral absorption, Dr. Dittman successfully developed a complex polymer matrix that allowed individuals the convenience of taking HGH Analog in an oral spray. The matrix encapsulates the HGH Analog molecule, allowing it to enter into the body through the oral mucosa. In addition, the matrix successfully preserves the normally unstable HGH Analog, eliminating the need for refrigeration and making it possible and convenient for general consumption. INTRODUCING A NEW LINE OF HGH ANALOGS Hybrid Somatotropin ( hsb) Products HGH Analog contains Hybrid Somatotropin-B (hsb). HSB is a biologically activated hybrid growth hormone, encapsulated in a sequentially structured high polymer matrix (designed for high molecular weight proteins), and ionized with essential macro and trace elements.

3 BIOTROPIN RESEARCH * IGF-1 levels were taken prior to supplementation and again 2-6 months after product subjects. * INGREDIENTS Hybrid Somatotropin-8 (hsb), sodium, calcium, silica, sulfur, and a high polymer matrix (in trace amounts). HOW HGH ANALOG WORKS The effectiveness of using interleukins and interferon in microdilution has been well established. Using micro-dilutions of hormones that mirror blood concentrations in, by definition, safe. Glandular hormone secretions frequently occur in parts per billion and even parts per billion. * was It is also important to understand how proteins are absorbed into their corresponding cellular receptor sites, Amino acids are the basic building blocks of protein structures. They exist in large sequences called polypeptides, and function in close cooperation with minerals, essential fatty acids, enzymes, and chemical bonds to perform specific functions, Proteins are absorbed most efficiently when they are bonded to minerals and enzymes. At HGH Research Laboratories, we use this understanding to formulate products that create both a physiological and energetic response. Most people think that the hormone itself is responsible for a given physiological reaction. Indeed, in its function as a messenger protein, growth hormone is integral to cellular communication, but it is the cell s response to the presence of HGH Analog that generates the physiological effects demonstrated in our research. The absorption of HGH Analog into the body through the oral mucosa is made possible by the polymer matrix technology. The principle behind the technology is that physiological changes occur in concert with multiple factors. In addition, these changes are best sustained and most responsive to influences that are gentle, specific, and biologically integrated. Our research suggests that HGH Analog delivered in microdilutions stimulates positive and sustained physiological changes. In contrast with growth hormone precursors, HGH Analog is biologically active, hybrid Somatotropin-B (hsb), preserved and stabilized in polymer matrix absorption technology. Precursors, while they may comprise a number of amino acids, cannot be preserved or delivered to achieve maximum GH potential. PURPOSE Two outcome based research studies were conducted. The purpose of the studies were to (1) measure the degree of physiologica response from micro-dilution HGH Analog supplementation and (2) validate polymer matrix technology as a method to stabilize, preserve, and deliver HGH Analog into the body through the oral mucosa.

4 I DESIGN The studies comprised 18 subjects; 11 male, 7 female. IGF-1 (insulin-like growth factor-l) readings were taken prior to commencement of supplementation and again after 2-6 months of product usage. Subjects received 3-4 sprays daily for a range of ng/ml per day. Out of the 18 tested, 13 began the study with IGF-1 readings with the normal range for their age and sex ( In range ), and 5 began with Out of range IGF-1 levels suggesting a weakened physiological state. IGF-1 Results for In Range Subjects IGF-1 Levels for Out-of Range Subjects Preliminary Study Results: Testosterone & DHEA Levels on 7 Subjects STUDY RESULTS Of the 13 In range subjects, 11 individuals (85%) experienced an average increase in IGF-1 of 34% (range of 11% to 80%). Of the Out of range subjects, 2 experienced an average increase of 52% (42 nglml) and 3 subjects experienced little change, respecting the body s sensitive condition.

5 EXPANDED PROTOCOL Six of the eighteen subjects were also tested for testosterone and DHEA. Levels were taken twice; once prior to commencement of supplementation, and again 3-6 weeks later. Subjects comprised 5 males and 1 female. Of the 5 males tested: 4 out of 5 males recorded an average increase in testosterone (range of 8% to 73%). 1 male s testosterone levels remained constant. 3 of 5 males recorded a reduction in DHEA (average 16%) as contrasted with 2 males showing an average 18% increase in DHEA. 1 female tested:. 1 female recorded a 27% increase in DHEA, offset by a 24% reduction in testosterone. For months I tried to lose weight and improve my energy level. First I tried a growth hormone precursor effect Then II tried HG Analog. After three m but my blood pressure heart condition sfabiliz ead. feel great. " P.B., the Netherlands I IGF-1 SUMMARY RESULTS: Average Percent Increase of 37%. Mean Increase of 28 nglml. P = % probability that the results occurred by chance SOME COMMONLY ASKED QUESTIONS Who should use HGH Analog? During somatopause (mid-life), there is a significant decline in levels of somatomedin-c, a liver hormone also known as Insulin-Like Growth Factor, or IGF-1. This results in a marked reduction in GH levels and a consequent decrease in physiological function. During somatopause, individuals lose their natural vitality as cells and organs gradually dehydrate and diminish in size and function. In addition, somatopause is associated with decreased immune system function and ability to resist infection. HGH Analog was designed to combat the impact of somatopause and to optimally raise growth hormone and IGF-1 levels. What lifestyle changes support the production of HGH Analog? The following key lifestyle factors all support the production of growth hormone: balanced nutrition; consumption of living whole foods;

6 Supplementation with synergistic vitamins, minerals, and amino acids; consistent exercise and strength training; adequate sleep, pure water; and limited consumption of processed foods, hydrogenated fats, sugars, salt, and alcohol. How can I track my physiological progress with HGH Analog? What tests should I have Done? GH levels are tested indirectly, with a blood test for IGF-1, which is a stable indicator of GH levels. Among other functions, GH regulates IGF-1 production in the liver. Most individuals over the age of 35 will have initial IGF-1 levels of 100 to 200 ng/ml In addition to IGF-1, consider the following blood and hormone panel: pregnenalone, thyroid ( T3, T7, TSH, TBG), progesterone, estrogens (estriol, estradiol, estrone), testosterone (freedihydro-, total-), DHEA, PSA, AMAST, and CA-125. Can anyone take HGH Analog? HGH Analog is safe and non-toxic. It is a micro-dilution hsb (Hybrid Somatotropin-B) product designed to minor the body s nature growth hormone secretions. However, if you are pregnant, under the age of 20, or if you have health concerns, please consult with a qualified health care professional prior to supplementation.