Carpal Tunnel Syndrome/ Cubital Tunnel Syndrome. Nerve anatomy. Pathophysiology 6/14/2014. Most common compression neuropathies of the upper extremity

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Evan Armstrong
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$to 5% lifetime risk Significant loss of productivity, income 2011: Median time off work 28 days-- longer than fractures, multiple injuries, amputations Nerve anatomy http://www.google.com/url?$ sa=i&rct=j&q=&source=ima ges&cd=&cad=rja&docid=h587bkmi5nwslm&tbnid=4z UC4WUgVVbSAM:&ved=0CAUQjRw&url=http%3A%2 F%2Fnerve.wustl.edu%2Fnd_compression.php&ei=uU KzUd6LCc3l4AOumoGABw&bvm=bv.47534661,d.

sa=i&rct=j&q=&source=ima ges&cd=&cad=rja&docid=h587bkmi5nwslm&tbnid=4z UC4WUgVVbSAM:&ved=0CAUQjRw&url=http%3A%2 F%2Fnerve.wustl.edu%2Fnd_compression.php&ei=uU KzUd6LCc3l4AOumoGABw&bvm=bv.47534661,d.

In chronic cases changes begin with breakdown of bloodnerve barrier, followed by edema and perineural thickening Increased endoneural pressure leads to circulatory changes and makes nerve susceptible

1 Carpal Tunnel Syndrome/ Cubital Tunnel Syndrome Justin Arnold MD Family Medicine Update 2014 Most common compression neuropathies of the upper extremity Increasing prevalence CTS 50/1000 subjects Up to 5% lifetime risk Significant loss of productivity, income 2011: Median time off work 28 days-- longer than fractures, multiple injuries, amputations Nerve anatomy ges&cd=&cad=rja&docid=h587bkmi5nwslm&tbnid=4z UC4WUgVVbSAM:&ved=0CAUQjRw&url=http%3A%2 F%2Fnerve.wustl.edu%2Fnd_compression.php&ei=uU KzUd6LCc3l4AOumoGABw&bvm=bv ,d.dmQ &psig=afqjcnggydumz6skxip4p4p- 9HEPf3jgWg&ust= Pathophysiology Spectrum of neural changes depends on force and duration of compression Neural ischemia contributes in acute cases In chronic cases changes begin with breakdown of bloodnerve barrier, followed by edema and perineural thickening Increased endoneural pressure leads to circulatory changes and makes nerve susceptible to dynamic ischemia Then leads to focal demyelination and finally axonal degeneration Complaints generally parallel histopathologic changes, as do sensory changes Neural changes may not occur uniformly across nerve Ie superficial fascicles affected earlier, LF,RF 1

Carpal Tunnel Syndrome (CTS) Symptomatic compressive neuropathy of the median nerve at the wrist, characterized physiologically by evidence of increase pressure within the carpal tunnel and decreased

$Structural, biological, genetic factors +/- environmental, occupational Idiopathic/ DM, RA/ HT, Pregnancy/Mass/fracture greens MN innervates: Pronator Teres FCR Palmaris Longus FDS IF, MF FDP$

2 Carpal Tunnel Syndrome (CTS) Symptomatic compressive neuropathy of the median nerve at the wrist, characterized physiologically by evidence of increase pressure within the carpal tunnel and decreased nerve function at that level. Structural, biological, genetic factors +/- environmental, occupational Idiopathic/ DM, RA/ HT, Pregnancy/Mass/fracture greens MN innervates: Pronator Teres FCR Palmaris Longus FDS IF, MF FDP Pronator Quadratus FPL Thenars (AbPb, OpP, FPb) 1,2 Lumbricals Potential sites of MN compression: Ligament of Struthers Lacertus Fibrosis Pronator heads Proximal edge of FDS Carpal tunnel Roof of carpal tunnel is flexor retinaculum (TCL) which spans from hamate and triquetrum ulnarly to scaphoid and trapezium radially Contains Median nerve and flexor tendons (4 FDS, 4 FDP, and FPL) Anatomy History Patients complain of numbness/tingling in digits and/or achy hand pain Duration? Severity/Character? When occur? Night? Driving? Telephone? Intermittent or constant? Aggravating/Alleviating factors? Location? Previous treatments? Bracing? CTR? Functional limitations? Medical history? DM, HT, Obesity, dialysis 2

Work issues? Observation Thenar atrophy?

crush, or if severe Evaluates only large

FDS-III, ResPro Treatment Injection Night

3 Work issues? Observation Thenar atrophy? Range of motion Strength exam APB Provocative tests MNCT Tinel s Phalens Sensory Testing* S2PD or Semmes-Weinstein Nl 4-5 mm Physical exam Sn/Sp MNCT / Tinel s / Phalen / Physical exam +/- Xrays-(AP, LAT, CT view) NCS/EMG If diagnosis not straightforward, concern for double crush, or if severe Evaluates only large myelinated fibers Just another piece of the puzzle Injection? Diagnostics Differential Radiculopathy Plexopathy Thoracic outlet Neuropathy Pronator syndrome Compression b/t pronator heads or FDS Thenar numbness (PCBMN) No night symptoms PE: resist FDS-III, ResPro Treatment Injection Night splinting Neutral! Injections Relief prognostic for successful surgery Nerve glides Nsaids Activity modification/work space evaluation Surgery 3

Nerve glides Work space eval Surgical Treatment Carpal tunnel

endoscopic equivalent results Uni vs bilateral Same day Local

3-4 wks Failure of conservative care Progression of symptoms

changes Acute Fracture Indications Mini-open CTR When to

4 Nerve glides Work space eval Surgical Treatment Carpal tunnel release (CTR) Divide TCL Open vs. endoscopic equivalent results Uni vs bilateral Same day Local +/- MAC No splint post-op No antibiotics needed* Activity mod 3-4 wks Failure of conservative care Progression of symptoms Patient preference Severe Constant symptoms Atrophy S2PD changes Acute Fracture Indications Mini-open CTR When to refer Constant symptoms Abnormal sensory testing Weakness/atrophy Failure of conservative measures 4

Cubital Tunnel Syndrome Second most common

C8-T1 Innervates: FCU RF,SF FDP Hypothenars

Pollicis Dp head FPB 5 anatomic sites of

intermuscular septum Medial epicondyle Osborne s

Traction pic History Complaints of numbness,

pain May affect hand strength in severe cases

$Ask about previous elbow injury (fracture) Ask$ about job demands-- prolonged flexion?

sign Froment s Range of motion Elbow flexion

5 Cubital Tunnel Syndrome Second most common compression neuropathy Ulnar nerve at the elbow C8-T1 Innervates: FCU RF,SF FDP Hypothenars (O/A/F) 3,4 Lumbricals Interossei Adductor Pollicis Dp head FPB 5 anatomic sites of compression Arcade of Struthers Medial intermuscular septum Medial epicondyle Osborne s ligament Flexor-pronator aponeurosis Anatomy Traction pic History Complaints of numbness, tingling in ring and/or small finger Usually not pain May affect hand strength in severe cases Worse when driving, sleeping, talking on the phone? Constant/intermittent? Clumsiness? Ask about previous elbow injury (fracture) Ask about job demands-- prolonged flexion? Observation Scars, atrophy Clawing Wartenberg s sign Froment s Range of motion Elbow flexion test/ulnar nerve compression test Tinel s UN* Subluxation? Strength (intrinsics) 1 st DI S2PD Physical exam SN Tinel s 70/ EFT 75; 89 >60 sec EFT/UNCT 98 5

Xrays (AP, Lat, Cub tunnel) Evaluate for arthritis, trauma NCS Rely more on with cubital tunnel

flexion Elbow pad Extension night splint Nerve glide exercises Majority of mild/moderate improve with conservative

to refer Cubital tunnel release +/- transposition Sub-cutaneous Intra-muscular Sub-muscular Surgical treatment

Traction pic Very common problems Take home Diagnosis is largely clinical Established non-operative treatments

6 Xrays (AP, Lat, Cub tunnel) Evaluate for arthritis, trauma NCS Rely more on with cubital tunnel Substantiate/refute early, baseline in severe Consider bilateral Diagnostics Activity modification Avoid prolonged flexion Elbow pad Extension night splint Nerve glide exercises Majority of mild/moderate improve with conservative measures Surgery Treatment Constant numbness Atrophy/weakness Abnormal S2PD Failure of conservative measures When to refer Cubital tunnel release +/- transposition Sub-cutaneous Intra-muscular Sub-muscular Surgical treatment Results equivalent between in-situ decompression and transposition Do simplest operation that relieves nerve Traction pic Very common problems Take home Diagnosis is largely clinical Established non-operative treatments that are successful in majority Splint, inject, OT-nerve glides Know when to say when Constant symptoms, abnormal sensory threshold, atrophy 6

Nerves of Upper limb. Dr. Brijendra Singh Professor & Head Department of Anatomy AIIMS Rishikesh

Nerves of Upper limb. Dr. Brijendra Singh Professor & Head Department of Anatomy AIIMS Rishikesh Nerves of Upper limb Dr. Brijendra Singh Professor & Head Department of Anatomy AIIMS Rishikesh 1 Objectives Origin, course & relation of median & ulnar nerves. Motor & sensory distribution Carpal tunnel