Evaluation of normal ankle cartilage by MRI T1ρ mapping

Transcription

1 Evaluation of normal ankle cartilage by MRI T1ρ mapping Ryuhei Katsui 1 MD Akira Taniguchi 2 MD, Ph. D Munehiro Ogawa 2 MD, Ph. D Hiroaki Kurokawa 2 MD Norihiro Samoto 3 MD, Ph. D Yasuhito Tanaka 2 MD, Ph. D 1 Department of Orthopaedic Surgery of Heisei Memorial Hospital 2 Department of Orthopaedic Surgery of Nara Medical University 3 Department of Orthopaedic Surgery of Nara Prefecture Medical Center

2 AOFAS Annual Meeting 2016 Disclosure of Conflict of Interest Ryuhei Katsui 1 MD Akira Taniguchi 2 MD, Ph. D Munehiro Ogawa 2 MD, Ph. D Hiroaki Kurokawa 2 MD Norihiro Samoto 3 MD, Ph. D Yasuhito Tanaka 2 MD, Ph. D We have no COI with regard to our presentation.

3 Background With the recent remarkable progresses in image diagnosis using magnetic resonance imaging (MRI), it could be possible to evaluate articular cartilage in detail. T1ρ mapping by MRI has recently drawn attention as a noninvasive cartilage evaluation method.

4 Purpose While its validity has been proven, there are no reports describing T1ρ mapping for the ankle; therefore, in this present study, T1ρ values of the articular cartilage surfaces of the talar dome were measured in healthy individuals. Materials 10 ankles from 10 healthy volunteers (4 male/ 6 female) The mean age was 31.6 years

5 Evaluations The trochlear ridge(b) of the talus and slices 10 mm anterior(a) and posterior(c) of the ridge. COR SAG A B C A B C Each slice was divided into trisecting (medial, central, and lateral) areas of the articular surface of the trochlea tali.

6 Measure Images taken using a 3.0 T MRI device, manufactured by Philips, were processed using the PRIDE software (Philips, Inc.) and analyzed using Image J, a specialized analysis software. PRIDE software Image J coloring

7 Results Lateral (L) Central (C) Medial (M) A; anterior 32.2±6.9ms 31.2±7.2ms 31.0±6.4ms B; trochlear ridge 25.1±5.5ms 21.7±5.6ms 24.2±4.2ms C; posterior 35.1±4.8ms 31.9±4.5ms 33.8±4.8ms This table shows the results of T1ρ values for the medial, central, and lateral regions respectively for the anterior talus, the trochlear ridge of the talus, the posterior talus.

8 Results T1ρ value A; anterior B; trochlear ridge C; posterior p=0.05 A B C A B C A B C L a t e r a l C e n t r a l M e d i a l T1ρ values were significantly lower in the trochlear ridge of the talus than in the anterior and posterior areas of the talar dome.

9 Discussion Proteoglycan content of articular cartilage in the talar dome was determined to be low in the anterior and posterior areas, that reveals load application might be concentrate on these areas. The thickness of articular cartilage in the ankle joint has been reported to be mm, that is thinner than that of the knee joint.

10 Discussion It has reported that proteoglycan composition ability of the ankle joint is higher than the knee joint, and the ankle joint cannot receive prevention of proteoglycan composition easily. As these reasons, the ankle joint cannot fall into osteoarthritis easily compared with the knee joint.

11 References 1. Li X, Benjamin Ma C, Link TM, Castillo DD, Blumenkrantz G, Lozano J, Carballido- Gamio J, Ries M, Majumdar S: In vivo T(1rho) and T(2) mapping of articular cartilage in osteoarthritis of the knee using 3 T MRI. Osteoarthritis Cartilage Jul;15(7): Epub 2007 Feb Shepherd DE, Seedhom BB : Thickness of human articular cartilage in joints of the lower limb. Ann Rheum Dis Jan;58(1): Cole AA, Kuettner KE: Molecular basis for differences between human joints. Cell Mol Life Sci Jan;59(1): Sugimoto K, Takakura Y, Tohno Y, Kumai T, Kawate K, Kadono K: Cartilage thickness of the talar dome. Arthroscopy Apr;21(4): Mosher TJ, Dardzinski BJ, Smith MB: Human articular cartilage: influence of aging and early symptomatic degeneration on the spatial variation of T2--preliminary findings at 3 T. Radiology Jan;214(1): Burstein D, Bashir A, Gray ML: MRI techniques in early stages of cartilage disease. Invest Radiol Oct;35(10): Ellermann J, Ling W, Nissi MJ, Arendt E, Carlson CS, Garwood M, Michaeli S, Mangia S: MRI rotating frame relaxation measurements for articular cartilage assessment. Magn Reson Imaging Nov;31(9): doi: /j.mri Epub 2013 Aug 30.