PRELIMINARY PROGRAM (as per 24 April 2018)

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1 PRELIMINARY PROGRAM (as per 24 April 2018) FRIDAY - 2 NOVEMBER :30-15:30 EDUCATIONAL SYMPOSIUM (Part 1) Clinical Dusica Babovic-Vuksanovic, MD Mimi Berman, MD Karin Cunha, PhD 13:30-15:30 ANIMAL MODELS (Part 1) Basic Pathology of Genetically Engineered NF Animal Models: Consensus Report Marco Giovannini, MD, PhD Nancy Ratner, PhD, Anat-Stemmer Rachamimov, MD 15:30-16:00 Break 16:00-18:00 EDUCATIONAL SYMPOSIUM (Part 2) Dusica Babovic-Vuksanovic, MD Mimi Berman, MD Karin Cunha, PhD 16:00-18:00 ANIMAL MODELS (Part 2) Pathology of genetically engineered NF animal models: consensus report Marco Giovannini, MD, PhD Nancy Ratner, PhD, Anat-Stemmer Rachamimov, MD 1 P a g e - N F P R E L I M I N A R Y P R O G R A M A P R I L

2 13:30-18:00 MEETING OF THE FRENCH LAY GROUP Session francophone / This session will be in French only - Les associations de malades et de parents contre les neurofibromatoses (Non for profit organizations and neurofibromatoses.) Jean-Michel Dubois, Annette Bakker - Neurofibromatose 2 (Neurofibromatosis 2) Gareth Evans, Michel Kalamarides - Les adolescents atteints de neurofibromatose 1 et 2 (Teen agers with neurofibromatoses 1 and 2) Ros Ferner, Marie Laure Armand - La prise en charge clinique de la neurofibromatose 1 (Clinical management of neurofibromatosis 1) Eric Legius, Patrick Combemale - Futur thérapeutique dans le domaine des neurofibromatoses (Therapeutic future of neurofibromatosis 1) Susan Huson, Pierre Wolkenstein - Modèles Animaux au cours des neurofibromatoses (Animal models in neurofibromatoses) Marco Giovannini, Piotr Topilko - Génétique des neurofibromatoses (Genetics in neurofibromatoses) Ludwine Messiaen, Dominique Vidaud. SATURDAY - 3 NOVEMBER :45-09:00 Welcome remarks 09:00-10:00 KEYNOTE LECTURE: DANNY REINBERG, PHD (USA) Topic: Cancer: The Regulation of Gene Expression in the Context of Chromatin 09:00-10:40 EUROPEAN ASSOCIATION MEETING 10:00-10:40 PLENARY SESSION: EPIGENETICS (PART 1) Eric Pasmant, PhD Thomas DeRaedt, PhD Karlyne Reilly, PhD 10:40-11:00 Break 11:00-12:00 EUROPEAN ASSOCIATION MEETING 2 P a g e - N F P R E L I M I N A R Y P R O G R A M A P R I L

3 11:00-12:00 PLENARY SESSION: EPIGENETICS (PART 2) Eric Pasmant, PhD Thomas DeRaedt, PhD Karlyne Reilly, PhD 12:00-13:00 Lunch break 13:00-14:00 KEYNOTE LECTURE: KRISTJAN JESSEN, PhD (UK) Topic: Schwann Cell Biology 14:00-15:30 PLENARY SESSION: SCHWANN CELLS AND NEUROFIBROMAS Lu Le, MD, PhD Juha Peltonen, MD, PhD Edu Serra, PhD 14:00-15:30 PARALLEL SESSION: SURGERY IN NF1 Laurent Lantieri, MD Xiaojie Hu, MD, PhD Joseph Gruss, MD 14:00-15:30 PARALLEL SESSION: PSYCHOLOGY WORKSHOP The participation to this session is by invitation 15:30-16:00 Break 16:00-17:30 PLENARY SESSION: PSYCHOSOCIAL IMPACT OF NEUROFIBROMATOSIS Marie-Laure Armand, PhD Staci Martin, PhD Hilda Crawford, PhD 17:20-17:30 POSTER ADVERTISEMENTS 17:30-19:00 BASIC SCIENCE POSTER SESSION SUNDAY - 4 NOVEMBER :00-10:00 KEYNOTE LECTURE: PAOLO G. CASALI, MD (Italy) Topic: Malignant Nerve Sheath Tumor: Improving the Prognosis 3 P a g e - N F P R E L I M I N A R Y P R O G R A M A P R I L

4 10:00-10:40 PLENARY SESSION: MUTATIONS IN OTHER CANCERS (PART 1) Meena Uphadyaha, PhD Partha Majumder, PhD Ophelia Maertens, PhD 10:40-11:20 Break 11:20-12:00 PLENARY SESSION: MUTATIONS IN OTHER CANCERS (PART 2) Meena Uphadyaha, PhD Partha Majumder, PhD Ophelia Maertens, PhD 12:00 13:00 Lunch break 13:00-14:30 NF2 AND SCHWANNOMATOSIS STATE OF THE ART (Part 1) Clinical - NF2/SWN Diagnostic criteria revision Gareth Evans, MD - Genetics of NF2/ SCHWANNOMATOSIS Gareth Evans, MD - Current and emerging drug treatment options Scott Plotkin, MD, PhD 13:00-14:30 PARALLEL SESSION: GLIOMA IN/OUT IF NF Michael Fisher, MD David Walker, MD Antonio Iavarone, MD 13:00-14:30 PARALLEL SESSION: FUNCTIONAL GENETICS AND INTERPRETATION/CLASSIFICATION OF VARIANT 14:30 15:00 break Akihiko Yoshimura, PhD Eric Legius, MD, PhD Frans Verheijen, PhD 15:00-17:00 NF2 AND SCHWANNOMATOSIS STATE OF THE ART (Part 2) - Treatment of Vestibular Schwannomas Michael Link, MD - Treatment of Meningiomas John Golfinos, MD - Hearing Rehabilitation Olivier Sterkers, MD - Treatment of Spinal Tumors 4 P a g e - N F P R E L I M I N A R Y P R O G R A M A P R I L

5 Andrew King, MD - Peripheral nerve schwannomas Allan Belzberg, MD - Management of NF2 in China H. Wu, MD 15:00-17:00 PARALLEL SESSION: LEARNING DISABILITIES Thijs van der Vaart, MD, PhD Jonathan Payne, PsyD Nicole Ullrich, MD, PhD 15:00-17:00 PARALLEL SESSION: GENETICS OF NF1 Ludwine Messiaen, PhD Hildegard Kehrer-Sawatzki, PhD Douglas Stewart, MD 17:00-17:10 POSTER ADVERTISEMENTS 17:10 18:40 CLINICAL POSTER SESSION MONDAY - 5 NOVEMBER 2018 MONDAY - 5 NOVEMBER :30-09:30 KEYNOTE LECTURE: PIER PAOLO PANDOLFI, MD, PHD (USA) Topic: Animal Models 09:30-10:50 PLENARY SESSION: MICROENVIRONMENT Piotr Topilko, PhD D. Wade Clapp, MD Alison Lloyd, PhD 09:30-10:50 PARALLEL SESSION: NF2/SCHWANNOMATOSIS Clinical Cases Panel Discussion Thomas Roland, New York University Michael Link, Mayo Clinic, US Brad Welling, Massachusetts Eye and Ear Institute, Harvard University, US Scott Plotkin, Massachusetts General Hospital, US John Golfinos, New York University, US Gareth Evans, Univ. of Manchester, UK 10:50 11:20 Break 5 P a g e - N F P R E L I M I N A R Y P R O G R A M A P R I L

6 11:20-12:40 PLENARY SESSION: PAIN AND PRURITIS IN NEUROFIBROMATOSIS Allan Belzberg, MD Ros Ferner, MD Scott Plotkin, MD, PhD 12:40 13:30 Lunch break 13:30-14:30 KEYNOTE LECTURE: CAROLINE ROBERT, MD, PHD (France) Topic: Targeted Therapy in Melanoma 14:30-15:30 KEYNOTE LECTURE: MARK E. DAVIS, PHD (USA) Topic: Nanomedicines and Cancers 15:30-16:30 PLATFORM PRESENTATIONS Basic 15:30-16:30 PLATFORM PRESENTATIONS Clinical 16:30-16:45 Break 16:45-18:15 PLENARY SESSION: MEDICAL AND SURGICAL CARE: A MULTIDISCIPLINARY APPROACH FOR NF Michel Kalamarides, MD, PhD Bruce Korf, MD, PhD Jaishri Blakeley, MD 16:45-18:15 PARALLEL SESSION: BIOLOGY OF NF2 AND SCHWANNOMATOSIS Helen Morrison, PhD Andrea McClatchey, PhD Jeremie Vitte, PhD TUESDAY - 6 NOVEMBER :30-09:30 ORAL POSTER PRESENTATIONS 09:30-10:30 KEYNOTE LECTURE: YVES LEVY, MD, PHD (France) Topic: Plan France Médecine Génomique P a g e - N F P R E L I M I N A R Y P R O G R A M A P R I L

7 10:30-10:50 PLENARY SESSION: NEUROFIBROMATOSIS: PAST, PRESENT AND FUTURE Co-Chairs: Annette Bakker, PhD Maurizio Clementi, MD 10:50-11:05 Break 11:05-12:25 PLENARY SESSION: NEUROFIBROMATOSIS: PRESENT, PAST AND FUTURE Chair: Maurizio Clementi, MD 12:25-13:45 PLENARY SESSION: REVISION OF DIAGNOSTIC CRITERIA 13:45-14:00 Congress Adjourned 15:00-18:00 REiNS session (bby invitation) Response Evaluation in Neurofibromatosis and Schwannomatosis 7 P a g e - N F P R E L I M I N A R Y P R O G R A M A P R I L

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