Free Papers Section 1: Moderators: Hans Grossniklaus & Jose Pulido

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1 2017 American Association of Ophthalmic Oncologists and Pathologists Annual Meeting Hampton Inn & Suites, Convention Center 1201 Convention Center Blvd. New Orleans, LA November 10, :30 8:00 Registration and Breakfast 8:00 8:06 Welcome Paul Bryar, President, AAOOP Free Papers Section 1: Moderators: Hans Grossniklaus & Jose Pulido 8:06-8:18 Comparison of the prognostic accuracy of gene expression-based classification versus TNM stagign in uveal melanoma 8:18-8:30 Prior immunosuppressive therapy does not confer increased risk of metastasis in uveal melanoma 8:30-8:42 Correlation of cytogenetic abnormalities with clinical features of uveal melanoma in 1059 patients 8:42-8:54 Choroidal Exudate in Enucleated Eyes with Retinoblastoma: A Pitfall in the Interpretation of Choroidal Invasion 8:54-9:06 Diagnostic yield of prognostication biopsy for uveal melanoma 9:06-9:18 Hepatic abnormalities identified by baseline MRI of Uveal melanoma patients J. William Harbour Jenna Kim Carol Shields Bertil Damato Arun Singh Federica Catalanotti

2 9:18-9:30 Iodine-125 Brachytherapy for Uveal Melanoma: A Systematic Review of Radiation Dose Jose Echegaray Special lecture 9:30-10:00 Advances in Cancer Management 2017: New pathways, new agents and new ocular toxicities Dan Gombos 10:00-10:30 Refreshment Break and Poster Session 1, Authors Present with Posters Germ cell tumor metastatic to eye and placenta, Katherine Paton et al. 2. A Jumping Diagnosis, Claudia Maria Prospero Ponce et al. 3. Sphenocavernous Syndrome Secondary to IgG4- Related Ophthalmic Disease, Ilyse Kornblau et al. 4. Varying Courses of Optic Nerve Sheath Meningiomas in Children: A Case Series, Nina Farivari et al Beaded Papules Localized to the Lid Margins of Both Eyes: A New Entity?, Hillary Stiefel et al. Fine Needle Aspiration Biopsy for Suspected Uveal Metastases, Claudine Bellerive et al. Free Papers Section 2: Moderators: Tatyana Milman & Mary Beth Aronow 10:30-10:42 Subfoveal choroidal thickness in fellow eyes of patients with circumscribed choroidal hemangioma 10:42-10:54 A 12-Year Study of Slotted Eye Plaque Radiation Therapy for Choroidal Melanoma: Near, Touching, or Surrounding the Optic Nerve 10:54-11:06 Ocular tuberculosis: Bacterial load correlates with the extent of caseous necrosis 11:06-11:18 Sirtuin inhibitor as a novel cell cycle checkpoint inhibitor and regulator of the TP53-MDM2 pathway in uveal melanoma Ethan Sobol Abhilasha Maheshwari Lei-Chi Wang Matthew Wilson

3 11:18-11:30 Expanding clinical and histopathologic spectrum of ocular melanocytomas 11:30-11:42 Primary Histiocytoid/Signet Ring Cell Carcinoma of the Eyelid: Clinicopathologic Analysis with Evaluation of the E-cadherin/B-catenin Complex and Associated Genetic Alterations 11:42-11:54 Eye sparing management of large ciliochoroidal melanoma Jerry A Shields Maria Del Valle Estopinal Zelia Correa Special lecture 11:54-12:30 Update in the Management of Ocular Surface Tumors Carol Karp 12:30-1:30 Lunch (provided) and Business Meeting (Regular Voting Members Only) Free Papers Section 3: Moderators: Hakan Demirci & Amy Schefler 1:30-1:42 Outcome of Intra-arterial Chemotherapy for Retinoblastoma: A seven- years Retrospective Study from China. 1:42-1:54 Screening Children at Risk for Retinoblastoma: Consensus Report from the American Association of Ophthalmic Oncologists & Pathologists 1:54-2:06 An International Collaboration of Retinoblastoma Presentation Statistics 2:06-2:18 Intravitreal Melphalan for Recurrent Sub-Retinal Seeding in Retinoblastoma 2:18-2:30 Ocular recurrences following ophthalmic artery chemosurgery for retinoblastoma 2:30-2:42 Atypical retinal pigment epithelial hyperplasia and glial proliferation masquerading as progressive recurrent retinoblastoma: a case report review and clinicopathologic correlation Jiejun Xia Alison Skalet Andrew Stacey David Abramson Ariana Levin Jesse Berry

4 Special lecture 2:42-3:12 Clinicopathologic Correlation of Tumor Seeds in Retinoblastoma Patricia Chévez-Barrios 3:12-3:42 Refreshment Break and Poster Session 2, Authors Present for Posters Retinal Lymphoma and Therapeutic Effect of Vitrectomy, Gregory Bever et al. 8. Spontaneous Regression of an Endocrine Mucin- Producing Sweat Gland Carcinoma of the Eyelid after Biopsy, Norberto Mancera et al. 9. Giant Cell Tumor of Soft Tissue, Mary Aronow et al. 10. It's Not a Chalazion: A first report of trichodiscoma in the eyelid, Nina Farivari et al Basosquamous Carcinoma: An Aggressive Variant of Basal Cell Carcinoma, Shilpa Gillella Reddy et al. Primary mucinous carcinoma of the eyelid: A case report, Carlos Vives-Alvarado et al. 13. Blastic Transformation of a Mantle Cell Lymphoma Presenting as an Enlarging Unilateral Orbital Mass, Matthew A De Niear et al. Free Papers Section 4: Moderators: Daniel Albert & Amanda Maltry 3:42-3:54 BRAF, NRAS and GNAQ mutations in conjunctival nevi Jasmine H Francis 3:54-4:06 Durable clinical response to anti-pd1 therapy for patients with metastatic orbital and conjunctival melanoma Bita Esmaeli 4:06-4:18 Berger's space-an anatomically privileged site? Jose Pulido 4:18-4:30 Ranibizumab for Radiation Retinopathy (RRR): A Prospective, Multicenter Trial of Monthly versus PRN Amy Schefler

5 Dosing for Radiation Retinopathy-Related Cystoid Macular Edema 4:30-4:42 Neutrophil-to-Lymphocyte ratio in sebaceous carcinoma 4:42-4:54 Prevalence of Uveal Metastases in Tennessee and the Contiguous States Randy Bowen Benjamin King 4:54-5:06 Intravitreal triamcinolone acetate for radiation maculopathy recalcitrant to high-dose intravitreal bevacizumab Sonal Chaugule 5:06-5:18 White tumors of the Eye and Ocular Adnexa Zeynel A. Karcioglu 5:18 Closing Remarks Paul Bryar, President, AAOOP Accreditation Statement This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the American Academy of Ophthalmology and the American Association for Ophthalmic Oncology and Pathology. The American Academy of Ophthalmology is accredited by the ACCME to provide continuing medical education for physicians. Credit Designation Statement The American Academy of Ophthalmology designates this live activity for a maximum of 7.25 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Financial Disclosures David Abramson Daniel Albert

6 Mary Beth Aronow Claudine Bellerive Greg Bever Randy Bowen Carol Karp Federica Catalanotti Sonal Chaugule Patricia Chévez- Barrios NASA Grant Support Zelia Correa Bertil Damato Hakan Demirci Biosciences Inc.- Consultant/Advisor Biosciences Inc.- Consultant/Advisor Maria Del Valle Estopinal

7 Sander Dubovy* Jose Echegaray Bita Esmaeli Nina Farivari Dan Gombos Consultant/Advis or Aura Biosciences.- Consultant/Advi sor Children s Oncology Group Lecture Fees Abbvie Consulting Consultant/Advisor ASCO Consultant/Advis or Houseman Wilkins Foundation Grant Support Lois Kurss Fund for Glaucoma Research Grant Support Hans Grossniklaus Clearside Biomedical Patents/Royalty NIH Grant Support J. William Harbour Patents/Royalty Consultant/Advi sor Zeynel Karcioglu Carol Karp Jenna Kim

8 Ilyse Kornblau Ariana Levin Alhilasha Maheshwari Amanda Maltry* Miguel Materin* Consultant/Advis or Vida Ventures- Consultant/Advi sor Tatyana Milman Katherine Paton Claudia Maria Prospero Ponce Jose Pulido Shilpa Reddy Amy Schefler Genentech-Grant Support Regeneron - Grant Support Allergan Consultant/ Advisor Carol Shields

9 Jerry Shields Arun Singh Isoaid LLC Consultant/ Advisor Consultant/Advi sor Aura Biosciences.- Equity Owner Alison Skalet Ethan Sobol Andrew Stacey Hilary Stiefel Carlos Vives-Alvarado Lei-Chi Wang Matthew Wilson Jiejun Xia *Designates a member of the Planning Committee AAOOP and AAO staff have no.

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