Bacterial, viral, protoozal and fungal infections of the CNS
|
|
|
- Malcolm Chandler
- 5 years ago
- Views:
Transcription
1 Bacterial, viral, protoozal and fungal infections of the CNS Prof. Isidro Ferrer, Institut Neuropatologia, Servei Anatomia Patològica, IDIBELL-Hospital Universitari de Bellvitge, Universitat de Barcelona, CIBERNED, Hospitalet de LLobregat; Spain
2 Ramon Casas, original for the poster Andrew Wyeth, Cristina s world (poliomyelitis)
3 Meningococcal meningitis B C A Purulent meningitis (A) and ventriculitis (B) with inflammatory infiltrates in the subarachnoid space (C) mainly composed of neutrophils (D) D
4 Meningococcal meningitis; meningeal vasculitis
5 Purulent meningitis and infarction of the MCA Purulent meningitis with associated purulent vasculitis of the middle cerebral artery (MCA) and massive infarction of the territory of the MCA
6 Focal acute septic encephalitis secondary to purulent otitis Haemorrhagic necrosis and perivascular inflammatory infiltrates
7 Whipple disease, cerebral involvement Multiple necrotic lesions in the basal ganglia, hippocampus and temporal lobe. Necrotic areas are filled with macrophages with PAS positive granular inclusions composed of cellular debris and bacteria
8 Whipple disease Multiple necrotic lesions in the basal ganglia. Necrotic areas are filled with macrophages with PAS positive granular inclusions
9 Cerebral abscess Vascularization of the capsule
10 Tuberculous meningitis Tuberculous meningitis and cerebral infarction due to vasculitis and occlusion of the meningeal blood vessels. Inflammatory infiltrates contain giant cells of Langhans (arrows)
11 Cerebral tuberculoma Langhans cell Poor vascular network in the capsule
12 Actinomycotic abscess Sulphur granule
13 Nocardiosis Nocardia asteroides in a cerebral abscess
14 Chronic hypertrophic meningitis A B Dense infiltrate of lymphocytes in the meninges (A) and hypertrophy of cortical blood vessels (B)
15 Viral encephalitis A B C Perivascular infiltrates of lymphocytes (A), microglial nodules and neuronophagia (B, C)
16 Herpetic necrotizing encephalitis: HSV-1 B C A Encephalitis mainly involves the orbitary cortex and temporal lobes (A). Perivascular infiltrates of lymphocytes (B); and intranuclear inclusions and cytoplasmic deposits immunostained with anti-herpes virus antibodies
17 Herpetic encephalitis Involvement of the temporal pole, temporal lobe, insula and hippocampus (arrows)
18 Herpetic necrotizing encephalitis: HSV-1 Involvement of the temporal lobes. Intranuclear inclusions and cytoplasmic deposits immunostained with anti-herpes virus antibodies
19 Cytomegalovirus A B Periventricular involvement (A, B). Large intranuclear inclusions in the periventricular glia (C). Large intranuclear inclusions, often multiple, in the retina (D) C D
20 Acute anterior poliomyelitis B D A C E Distribution of lesions in the spinal cord (A); subacute stage with macrophages filed with neutral lipids (B and C); chronic stage: loss of motor neurons in the anterior horn and aberrant remaining motor neurons (D, E): post-polio
21 Human immunodeficiency virus-1: HIV-1 retrovirus HIV-1 encephalitis with infiltration of lymphocytes, microglial nodules, and small foci of demyelination
22 Paediatric HIV-1 infection A B C D E Brain calcifications in the cortex and basal ganglia (A, C). Generalized encephalitis with microglial nodules (D) and rare multinucleated cells (E)
23 Progressive multifocal leukoencepaholopathy, polyomavirus virus JC B A C D Multiple foci of demyelination in the cerebrum (A, B, arrows), aberrant astrocyte (C), and positive glial cells to specific JCV probe by in situ hybridization (D)
24 Progressive multifocal leukoencepaholopathy, polyomavirus virus JC Multiple confluent demyelinating lesions in the white matter of the cerebrum, cerebelllum and brain stem
25 Progressive multifocal leukoencepaholopathy, polyomavirus virus JC Foci of demyelination in the white matter of the cerebellum and pons (A). Bizarre glial cells with nuclear inclusions (B, C). Positive in situ hybridation for JCV (D) A C B D
26 Subacute sclerosing panencephalitis, measles virus B A C Reduced cortical thickness and myelin pallor (A). Intranuclear and cytoplasmic inclusions composed of packed tubules (B, C)
27 Toxoplasmosis B A Bilateral mass lesions with necrosis (A). Toxoplasma gondii in the vicinity of the lesions (B)
28 Multiple necrotic lesions caused by embolism of Aspergillus PAM staining. Fungi in the lumen of the vessels, in the vessel walls and in the cerebral parenchyma
29 Multiple necrotic foci due to Monosporium infection Methenamine silver staining PAM
30 Candidiasis
31 Cerebral mucormycosis A B Mucor sp, HE (A), PAM staining (B)
32 Cryptococcosis Clear cyst lesions in the striatum. Cryptoccocal yeasts in the cysts with no inflammation
33 Cryptococcosis Cryptococcus clear yeasts in cystic lesions
34 Cysticercosis, larvae of Taenia solium Several cysts located in the ventricle, cerebral parenchyma and cerebellum
35
Unit VIII Problem 6 Pathology: Meningitis
Unit VIII Problem 6 Pathology: Meningitis - Important terms: Meningitis: it is inflammation of meninges (coverings of the central nervous system) caused by infection. They are classified to: Pachymeningitis:
Vasculitides in Surgical Neuropathology Practice
Vasculitides in Surgical Neuropathology Practice USCAP requires that all faculty in a position to influence or control the content of CME disclose any relevant financial relationship WITH COMMERCIAL INTERESTS
Avian Pathology. Bacterial diseases: histo slides. ECVP-ESVP Summer School 2012 Frédérique NGUYEN
Avian Pathology Bacterial diseases: histo slides ECVP-ESVP Summer School 2012 Frédérique NGUYEN Bacterial diseases: histo slides B1. Turkey. Organs? Morphologic diagnosis? Special procedure? B2. Hen. Organ?
CNS infections (1 of 2)
CNS infections (1 of 2) How can microbes enter the nervous system? Hematogenous the most common mostly arterial can be from facial veins (through anastomoses with venous sinuses of the skull) Direct implantation
The Neurology of HIV Infection. Carolyn Barley Britton, MD, MS Associate Professor of Clinical Neurology Columbia University
The Neurology of HIV Infection Carolyn Barley Britton, MD, MS Associate Professor of Clinical Neurology Columbia University HIV/AIDS Epidemiology World-wide pandemic, 40 million affected U.S.- Disproportionate
Role of imaging (images) in my practice. Dr P Senthur Nambi Consultant Infectious Diseases
Role of imaging (images) in my practice Dr P Senthur Nambi Consultant Infectious Diseases Medical images: My thoughts Images are just images Subject to the intellect of the interpreter View it in conjuction
Kathleen R. Fink, MD Virginia Mason Medical Center. 6 th Nordic Emergency Radiology Course 2017
Kathleen R. Fink, MD Virginia Mason Medical Center 6 th Nordic Emergency Radiology Course 2017 Disclosure My spouse receives research salary support from: Guerbet Outline Indications for imaging CNS infections
Menigitidis. Dr Rodney Itaki Lecturer Anatomical Pathology Discipline
Menigitidis Dr Rodney Itaki Lecturer Anatomical Pathology Discipline University of Papua New Guinea Division of Pathology School of Medicine & Health Sciences Review Normal Microanatomy Image Ref: www.histology-world.com
Nervous system. Dr. Rawaa Salim Hameed
Nervous system Dr. Rawaa Salim Hameed Central nervous system (CNS) CNS consists of the brain (cerebrum, cerebellum, and brainstem) and spinal cord CNS is covered by connective tissue layers, the meninges
MR neuroimaging of HIV infected patients : A pictorial review
MR neuroimaging of HIV infected patients : A pictorial review Poster No.: R-0198 Congress: 2014 CSM Type: Scientific Exhibit Authors: P. F. Kwan, R. Thomas, A. Dixon; SOUTH YARRA/AU Keywords: Neuroradiology
Neuroradiology of AIDS
Neuroradiology of AIDS Frank Minja,, HMS IV Gillian Lieberman MD September 2002 AIDS 90% of HIV patients have CNS involvement 1 10% of AIDS patients present first with neurological symptoms 2 73-80% of
DES 9 janvier P. David. Clinic of Neuroradiology Erasme Hospital Université Libre de Bruxelles Belgium
DES 9 janvier 2015 P. David Clinic of Neuroradiology Erasme Hospital Université Libre de Bruxelles Belgium CNS Infections Early recognition in children, infants Longterm effects on the brain :devastating
An Approach. to Brain. Infection. 37F found down. Disclosures. Approach to CNS Infection. Objectives. Parenchymal. None.
An Approach Disclosures to Brain None. Infection Jason Shewchuk, MD Clinical Associate Professor Head of Neuroradiology UBC European Course in Neuroradiology 2018 Objectives Following this session the
IMAGING OF INTRACRANIAL INFECTIONS
IMAGING OF INTRACRANIAL INFECTIONS Dr Carolina Kachramanoglou LYSHOLM DEPARTMENT OF NEURORADIOLOGY NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY Plan Introduce MR sequences that are useful in the diagnosis
INFECTIONS OF THE NERVOUS SYSTEM. By: Shifaa Al Qa qa
INFECTIONS OF THE NERVOUS SYSTEM By: Shifaa Al Qa qa Infectious agents may reach the nervous system through several routes of entry: - Hematogenous spread---- mc - Direct implantation - Local extension
Opportunistic infections in the era of cart, still a problem in resource-limited settings
Opportunistic infections in the era of cart, still a problem in resource-limited settings Cristiana Oprea Victor Babes Clinical Hospital for Infectious and Tropical Diseases, Bucharest, Romania Assessment
BBS2711 Virology. Central Nervous System (CNS) Viruses. Dr Paul Young, Department of Microbiology & Parasitology.
BBS2711 Virology Central Nervous System (CNS) Viruses Dr Paul Young, Department of Microbiology & Parasitology. p.young@mailbox.uq.edu.au Viruses of the CNS Many human pathogenic viruses are capable of
Vascular Disorders. Nervous System Disorders (Part B-1) Module 8 -Chapter 14. Cerebrovascular disease S/S 1/9/2013
Nervous System Disorders (Part B-1) Module 8 -Chapter 14 Overview ACUTE NEUROLOGIC DISORDERS Vascular Disorders Infections/Inflammation/Toxins Metabolic, Endocrinologic, Nutritional, Toxic Neoplastic Traumatic
CEREBROVASCULAR DISEASES. By: Shifaa AlQa qa
CEREBROVASCULAR DISEASES By: Shifaa AlQa qa Cerebrovascular diseases Brain disorders caused by pathologic processes involving blood vessels 3 pathogenic mechanisms (1) thrombotic occlusion, (2) embolic
NACC Vascular Consortium. NACC Vascular Consortium. NACC Vascular Consortium
NACC Vascular Consortium NACC Vascular Consortium Participating centers: Oregon Health and Science University ADC Rush University ADC Mount Sinai School of Medicine ADC Boston University ADC In consultation
RINGS N THINGS: Imaging Patterns in Differential Diagnosis. Anne G. Osborn, M.D.
RINGS N THINGS: Imaging Patterns in Differential Diagnosis Anne G. Osborn, M.D. ExpDDxs: Intra-axial (Parenchymal) Lesions Ring-enhancing lesions, solitary 1 Ring-enhancing lesion crossing corpus callosum
FOCAL NEUROLOGICAL DEFICIT in HIV PATIENTS -a case based approach. Dr Jency Maria Koshy, CMC, Ludhiana
FOCAL NEUROLOGICAL DEFICIT in HIV PATIENTS -a case based approach Dr Jency Maria Koshy, CMC, Ludhiana Case 1 Middle aged gentleman Diagnosed to have HIV 5 months prior to admission CD4 at the time of detection-132
HIV and CNS Stereotactic Biopsy in the diagnosis of brain lesions in AIDS patients
HIV and CNS Stereotactic Biopsy in the diagnosis of brain lesions in AIDS patients Department of Neurosurgery Infectious Diseases Hospital, University of Buenos Aires, Argentina Definition AIDS Patients
CNS pathology Third year medical students. Dr Heyam Awad 2018 Lecture 1: an introduction
CNS pathology Third year medical students Dr Heyam Awad 2018 Lecture 1: an introduction CNS course This is a 7 hour course and the topics covered are important for your clinical years and your work as
Histology of the CNS
Histology of the CNS Lecture Objectives Describe the histology of the cerebral cortex layers. Describe the histological features of the cerebellum; layers and cells of cerebellar cortex. Describe the elements
Disclosure. + Outline. Case-based approach to neurological emergencies that might present to the ED
Kathleen R. Fink, MD University of Washington 5 th Nordic Emergency Radiology Course May 21, 2015 Disclosure My spouse receives research salary support from: Bracco BayerHealthcare Guerbet Outline Case-based
CNS INFECTIONS II Reid Heffner, M.D. Department of Pathology and Anatomical Sciences December 13, 2018
CNS INFECTIONS II Reid Heffner, M.D. Department of Pathology and Anatomical Sciences December 13, 2018 Robbins Basic Pathology. 10 th ed. Chap. 23, pp. 862-870 I HAVE NO CONFLICTS OF INTEREST OR DISCLOSURES
Brain Pain Infections of the CNS
FRIDAY, OCTOBER 28, 2016 Brain Pain Infections of the CNS Suyash Mohan MD, PDCC Assistant Professor of Radiology & Neurosurgery Division of Neuroradiology, Department of Radiology Perelman School of Medicine
Nervous System Defenses
Chapter 19 Infectious Diseases: Nervous System Topics - Nervous System Defenses - Nervous System Diseases Nervous System Defenses Nervous system Normal flora 1 2 Nervous system Central nervous system (CNS)
Brain Imaging. IC calcifications. Mamdouh mahfouz MD
Brain Imaging IC calcifications www.ssregypt.com Mamdouh mahfouz MD mamdouh.m5@gmail.com CT Hyper dense [ more than100 HU ] MRI Low signal in T1 and T2 WIs [non mobile protons] Exceptions Minute calcifications
Immunohistochemical Confirmation of Infections
Immunohistochemical Confirmation of Infections Danny A. Milner, Jr, MD, MSc, FCAP The Brigham and Women s Hospital Harvard Medical School Boston, Masschusetts USA Judicious Use of Immunohistochemistry
CNS pathology Third year medical students,2019. Dr Heyam Awad Lecture 1: an introduction: Nervous system cells and their response to injury.
CNS pathology Third year medical students,2019 Dr Heyam Awad Lecture 1: an introduction: Nervous system cells and their response to injury. CNS course This is a 7 hour course and the topics covered are
Central Nervous System Practical Exam. Chapter 12 Nervous System Cells. 1. Please identify the flagged structure.
Central Nervous System Practical Exam Chapter 12 Nervous System Cells 1. Please identify the flagged structure. 2. Please identify the flagged structure. 3. Please identify the flagged structure. 4. A
The pathogenesis of nervous distemper
Veterinary Sciences Tomorrow - 2004 The pathogenesis of nervous distemper Marc Vandevelde Canine distemper is a highly contagious viral disease of dogs and of all animals in the Canidae, Mustellidae and
Cerebral hemisphere. Parietal Frontal Occipital Temporal
Cerebral hemisphere Sulcus / Fissure Central Precental gyrus Postcentral gyrus Lateral (cerebral) Parieto-occipital Cerebral cortex Frontal lobe Parietal lobe Temporal lobe Insula Amygdala Hippocampus
IV. Cerebrovascular diseases
IV. Cerebrovascular diseases - Cerebrovascular disease denotes brain disorders caused by pathologic processes involving the blood vessels. - The three main pathogenic mechanisms are: 1. Thrombotic occlusion
Cerebro-vascular stroke
Cerebro-vascular stroke CT Terminology Hypodense lesion = lesion of lower density than the normal brain tissue Hyperdense lesion = lesion of higher density than normal brain tissue Isodense lesion = lesion
Histopathology: Cell necrosis and cytoplasmic accumulations
Histopathology: Cell necrosis and cytoplasmic accumulations These presentations are to help you identify basic histopathological features. They do not contain the additional factual information that you
A challenging neurological complication in a young HIV-infected woman
A challenging neurological complication in a young HIV-infected woman Ianache Irina-Cristiana Vi tor Ba es Clini al Hospital for Infectious and Tropical Diseases Bucharest - HIV/AIDS department Assessment
Cerebral Toxoplasmosis in HIV-Infected Patients. Ahmed Saad,MD,FACP
Cerebral Toxoplasmosis in HIV-Infected Patients Ahmed Saad,MD,FACP Introduction Toxoplasmosis: Caused by the intracellular protozoan, Toxoplasma gondii. Immunocompetent persons with primary infection
Imaging findings in CNS infections and differential diagnosis. M. Lequin
Imaging findings in CNS infections and differential diagnosis M. Lequin OUTLINE Introduction and terminology Diagnosis & Differential diagnosis Pediatric brain infections viral infections Meningitis Encephalitis
The central nervous system
Sectc.qxd 29/06/99 09:42 Page 81 Section C The central nervous system CNS haemorrhage Subarachnoid haemorrhage Cerebral infarction Brain atrophy Ring enhancing lesions MRI of the pituitary Multiple sclerosis
Figure 2: Lymph node Cortical follicular (F) and paracortical (PC) atrophy, with narrowing of the cortex relative to the medulla (M).
Figure 1: Lymph node Follicular hyperplasia, with expansion of the follicular germinal centres (F) by large blast cells. Paracortical hyperplasia, with expansion of the paracortex (PC) by small lymphocytes.
Contents 1 Normal Histology and Commonly Used Stains 2 Basic Pathologic Reactions
Contents 1 Normal Histology and Commonly Used Stains.... 1 1.1 Cells of the Nervous System... 1 1.1.1 Neurons... 1 1.1.2 Astrocytes.... 2 1.1.3 Oligodendrocytes... 5 1.1.4 Schwann Cells... 5 1.1.5 Ependyma....
Index. B Biological factors, 2 Brain stem encephalitis, Burkitt s lymphoma, 83, 105
Index A Acquired immunodeficiency syndrome (AIDS) abdomen gallbladder complications, 97, 107 109 gastrointestinal complications, 96, 105 106 liver complications, 97, 107 109 neoplasm, 99, 110 111 pancreas
HYPERTENSIVE ENCEPHALOPATHY
HYPERTENSIVE ENCEPHALOPATHY Reversible posterior leukoencephalopathy syndrome Cause Renal disease Pheochromocytoma Disseminated vasculitis Eclampsia Acute toxemia Medications & illicit drugs (cocaine)
Ar Neuropathologica 9 Springer-Verlag 1990
Acta Neuropathol (1990) 80:666-670 Ar Neuropathologica 9 Springer-Verlag 1990 Evolution of post-natal Herpes simplex virus encephalitis to multicystic encephalopathy Y. Chang, D. Softer, D. S. Horonpian,
Neuropathology Inflammation, Infection, Demyelination in the CNS
Neuropathology Inflammation, Infection, Demyelination in the CNS PathoBasic 2016-09-20 Jürgen Hench Inflammation in the CNS inflammation generally as a reaction against pathogen, substance, necrotic, or
CT and MR findings of systemic lupus erythematosus involving the brain: Differential diagnosis based on lesion distribution
CT and MR findings of systemic lupus erythematosus involving the brain: Differential diagnosis based on lesion distribution Poster No.: C-2723 Congress: ECR 2010 Type: Educational Exhibit Topic: Neuro
20 PATHOLOGY OF NERVOUS SYSTEM. Encephalitis Encephalomalacia Spongiform Encephalopathy Meningitis Neuritis Model Questions
20 PATHOLOGY OF NERVOUS SYSTEM Encephalitis Encephalomalacia Spongiform Encephalopathy Meningitis Neuritis Model Questions Nervous system is composed of brain, spinal cord, and peripheral nerves. The neuron
Neurotransmitter: dopamine. Physiology of additive drugs. Dopamine and reward. Neurotransmitter: dopamine
Physiology of additive drugs Cocaine, methamphetamine, marijuana, and opiates influence the neurotransmitter dopamine. Neurotransmitter: dopamine Dopamine - a neurotransmitter associated with several functions,
Cellular Pathology. Histopathology Lab #2 (web) Paul Hanna Jan 2018
Cellular Pathology Histopathology Lab #2 (web) Paul Hanna Jan 2018 Slide #91 Clinical History: a necropsy was performed on an aged cat the gross pathological changes included: widespread subcutaneous edema
Supplementary Appendix
Supplementary Appendix This appendix has been provided by the authors to give readers additional information about their work. Supplement to: Tavakoli NP, Wang H, Dupuis M, et al. Fatal case of deer tick
Pathologic Analysis of CNS Surgical Specimens
2015 Kenneth M. Earle Memorial Neuropathology Review Pathologic Analysis of CNS Surgical Specimens Peter C. Burger, MD Interdisciplinary Quality Control Familiarity with entities Use of diagnostic algorithm
Blood Supply of the CNS
Blood Supply of the CNS Lecture Objectives Describe the four arteries supplying the CNS. Follow up each artery to its destination. Describe the circle of Willis and its branches. Discuss the principle
Characteristic features of CNS pathology. By: Shifaa AlQa qa
Characteristic features of CNS pathology By: Shifaa AlQa qa Normal brain: - The neocortex (gray matter): six layers: outer plexiform, outer granular, outer pyramidal, inner granular, inner pyramidal, polymorphous
Cerebrovascular diseases-2
Cerebrovascular diseases-2 Primary angiitis of CNS - Other causes of infarction i. Hypercoagulable states ii. Drug-abuse such as amphetamine, heroin and cocain Note - The venous side of the circulation
This is the second learning component (Learning Component 2) in our first learning module (Learning Module 1). In this component we review a very
This is the second learning component (Learning Component 2) in our first learning module (Learning Module 1). In this component we review a very basic response to injury inflammation. We ll look at examples
Tumors of the Nervous System
Tumors of the Nervous System Peter Canoll MD. PhD. What I want to cover What are the most common types of brain tumors? Who gets them? How do they present? What do they look like? How do they behave? 1
Citation 熱帯医学 Tropical medicine 36(2). p57-6
NAOSITE: Nagasaki University's Ac Title Author(s) Progressive Multifocal Leukoencepha with Acquired Immunodeficiency Synd Mwinyimtwana, Ahmed Makata; Toriyam Saburo Citation 熱帯医学 Tropical medicine 36(2).
3.02 Understand the functions and disorders of the nervous system Understand the functions and disorders of the nervous system
3.02 Understand the functions and disorders of the nervous system 1 3.02 Essential Questions What are the functions of the nervous system? What are some disorders of the nervous system? How are nervous
MORPHOLOGIC DIAGNOSIS: Liver: Hepatitis, necrotizing, multifocal to coalescing, severe, with numerous trichomonads. (3 pt)
Case 1. Tissue from a pelican. MICROSCOPIC DESCRIPTION: Liver: Approximately 80% (1 pt) of the liver is replaced by multifocal to coalescing areas of coagulative and lytic necrosis. Centrally, within these
Acute neurological syndromes
Acute neurological syndromes Assoc.Prof. Murat Sayan Kocaeli Üniversitesi, Rutin PCR Lab. Sorumlu Öğt.Üyesi Yakın Doğu Üniversitesi, DESAM Kurucu Öğrt. Üyesi sayanmurat@hotmail.com 0533 6479020 Medical
Imaging in a confused patient: Infections and Inflammation
American Society of Neuroimaging Imaging in a confused patient: Infections and Inflammation January 21, 2017 Los Angeles, California Joshua P. Klein, MD, PhD, FANA, FAAN, FASN Chief, Division of Hospital
CNS third year med students Summary of midterm material H Awad
CNS third year med students 2018 Summary of midterm material H Awad Dear All This presentation summaries the main important topics covered in the midterm material ( lectures 1-6) There will be two questions
Organization of The Nervous System PROF. MOUSAED ALFAYEZ & DR. SANAA ALSHAARAWY
Organization of The Nervous System PROF. MOUSAED ALFAYEZ & DR. SANAA ALSHAARAWY Objectives At the end of the lecture, the students should be able to: List the parts of the nervous system. List the function
Cell injury, adaptation and death. Unite one Second Lab.
Cell injury, adaptation and death Unite one Second Lab. The two lung abscesses seen here are examples of liquefactive necrosis in which there is a liquid center in an area of tissue injury. One abscess
Content. Polyarteritis nodosa. Vasculitis. Giant cell arteritis. Primary cerebral angiitis. Other autoimmune CNS disease.
Content Other autoimmune CNS disease Philippe Demaerel Vasculitis Systemic lupus erythematosus Wegener granulomatosis Behçet disease Rhombencephalitis - CLIPPERS Neurosarcoidosis Langerhans cell histiocytosis
RING ENCHANCING LESION BY M.S. HEMHNATH
RING ENCHANCING LESION BY M.S. HEMHNATH A 21 YRS FEMALE CAME WITH H/O HEADACHE AND SEIZURE FOR THE PAST ONE MONTH. NO OTHER FOCAL NEUROLOGICAL DEFICIT. DIFFERENTIAL DIAGNOSIS For this case are Neurocysticerosis
A pictorial review of neurological complications of systemic lupus erythematosus and antiphospholipid syndrome
A pictorial review of neurological complications of systemic lupus erythematosus and antiphospholipid syndrome Poster No.: C-2780 Congress: ECR 2010 Type: Educational Exhibit Topic: Neuro Authors: E. Tavernaraki,
8.3 The Central Nervous System. SBI4U Ms. Ho-Lau
8.3 The Central Nervous System SBI4U Ms. Ho-Lau The Central Nervous System the structural and functional centre for the entire nervous system the site of neural integration and processing The Central
PATHOLOGY Intracellular Degeneration LAB 1
PATHOLOGY Intracellular Degeneration LAB 1 Cellular swelling Liver Organ :- Liver Lesion :- 1. Narrowing of hepatic sinusoids due to the swelling of hepatocyte. 2. The cytoplasm of affected hepatocyte
Attenuation value in HU From -500 To HU From -10 To HU From 60 To 90 HU. From 200 HU and above
Brain Imaging Common CT attenuation values Structure Air Fat Water Brain tissue Recent hematoma Calcifications Bone Brain edema and infarction Normal liver parenchyma Attenuation value in HU From -500
Acute Ischaemic Stroke
Acute Ischaemic Stroke CT or MR SCA READIG FORM SCA ID: DATE OF READIG: SCA QUALIT: Good Moderate Poor Comment: READER ID: TPE OF SCA: CT: Without contrast: With contrast: MR: Diffusion: Perfusion ote
HIV-1 Infection of the Central Nervous System
CNS Alterations in HIV-1 Infection 81 2 HIV-1 Infection of the Central Nervous System Andreas Büttner, MD and Serge Weis, MD CONTENTS INTRODUCTION EPIDEMIOLOGY GROSS ANATOMICAL CHANGES CHANGES PRIMARILY
Acute stroke. Ischaemic stroke. Characteristics. Temporal classification. Clinical features. Interpretation of Emergency Head CT
Ischaemic stroke Characteristics Stroke is the third most common cause of death in the UK, and the leading cause of disability. 80% of strokes are ischaemic Large vessel occlusive atheromatous disease
Prion diseases or transmissible spongiform encephalopathies (TSEs)
Prion diseases or transmissible spongiform encephalopathies (TSEs) rare progressive neurodegenerative disorders that affect both humans and animals. They are distinguished by long incubation periods, characteristic
NEURO IMAGING 2. Dr. Said Huwaijah Chairman of radiology Dep, Damascus Univercity
NEURO IMAGING 2 Dr. Said Huwaijah Chairman of radiology Dep, Damascus Univercity I. EPIDURAL HEMATOMA (EDH) LOCATION Seventy to seventy-five percent occur in temporoparietal region. CAUSE Most likely caused
HIV and Dementia. London Dementia Clinical Network 14 June Dr Patricia McNamara MB BCh BAO MRCP PhD. Locum Consultant Neurologist, NHNN
HIV and Dementia London Dementia Clinical Network 14 June 2018 Dr Patricia McNamara MB BCh BAO MRCP PhD Locum Consultant Neurologist, NHNN Patricia.mcnamara2@nhs.net History of HIV Infection HIV 36 million
CEREBROVASCULAR DISEASES. By: Shifaa AlQa qa
CEREBROVASCULAR DISEASES By: Shifaa AlQa qa Cerebrovascular diseases Brain disorders caused by pathologic processes involving blood vessels 3 pathogenic mechanisms (1) thrombotic occlusion, (2) embolic
Pathology lab 4 DONE BY : MORAD ABU QAMAR
Pathology lab 4 DONE BY : MORAD ABU QAMAR Chronic interstitial inflammation, lung Certain etiologic agents such as viruses are more likely to lead to chronic inflammation, as seen here in the lung of a
May He Rest in Peace
May He Rest in Peace Neurologic Complications of AIDS Medical Knowledge Fiesta 2012 Paul K. King MD pkingmd@yahoo.com Objectives definition of HIV/AIDS what are the neurologic complications of AIDS how
CNS Infections in the Pediatric Age Group
CNS Infections in the Pediatric Age Group Introduction CNS infections are frequently life-threatening In the Philippines, bacterial meningitis is one of the top leading causes of mortality in children
Effect of Viruses on Tissue Culture
Pan American Society for Clinical Virology presents Effect of Viruses on Tissue Culture CDC Slide Set Provided by the National Laboratory Training Network* *Reproduced and distributed with permission Normal
Autopsy findings in 51 year-old man with mantle cell lymphoma
Autopsy findings in 51 year-old man with mantle cell lymphoma Bobbi S. Pritt, MD, MSc Professor of Laboratory Medicine and Pathology Mayo Clinic Disclosure of Relevant Financial Relationships USCAP requires
Cerebral infections. Introduction NEURO. Spyros Karampekios John Hesselink
Eur Radiol (2005) 15: 485 493 DOI 10.1007/s00330-004-2556-1 NEURO Spyros Karampekios John Hesselink Cerebral infections Received: 5 July 2004 Revised: 18 October 2004 Accepted: 19 October 2004 Published
The Neuropathology of West Nile Virus Meningoencephalitis A Report of Two Cases and Review of the Literature
Anatomic Pathology / WEST NILE VIRUS MENINGOENCEPHALITIS The Neuropathology of West Nile Virus Meningoencephalitis A Report of Two Cases and Review of the Literature Todd W. Kelley, MD, 1 Richard A. Prayson,
What Are We Going to Do? Fourth Year Meds Clinical Neuroanatomy. Hydrocephalus and Effects of Interruption of CSF Flow. Tube Blockage Doctrine
Fourth Year Meds Clinical Neuroanatomy Ventricles, CSF, Brain Swelling etc. David A. Ramsay, Neuropathologist, LHSC What Are We Going to Do? Hydrocephalus and some effects of the interruption of CSF flow
Central Nervous System Infection
Central Nervous System Infection Ashley H. Aiken KEYWORDS CNS infections Meningitis Abscess Encephalitis Subdural empyema Infections of the brain and its linings pose a growing, worldwide health problem.
Disclosure. Learner Objectives. Congenital Infections. Question. Main Categories 4/26/2016
Communicating Communicability: Imaging of CNS Infections Aaron P. Kamer, MD Assistant Professor of Clinical Radiology Neuroradiology Section April 26, 2016 Disclosure Within the past 12 months: I have
Central Nervous System Immune Reconstitution Disease: Pathology
Central Nervous System Immune Reconstitution Disease: Pathology F.Gray, H.Adle-Biassette, F.Héran, G. Pialoux, A.Moulignier, APHP Hôpital Lariboisière Université Paris VII Introduction of HAART, which
Pleomorphic Xanthoastrocytoma
Pleomorphic Xanthoastrocytoma Christine E. Fuller Keywords Pleomorphic xanthoastrocytoma; Pleomorphic xanthoastrocytoma with anaplastic features 2.1 OVERVIEW Pleomorphic xanthoastrocytoma (PXA) is an uncommon
PARA210 SUMMARY Hyperglycaemia (DKA & HHS) Brain & Nervous System Anatomy & Physiology Degenerative Neurological Disorders
PARA210 SUMMARY Page Topic 01-03 Diabetes Mellitus 04-05 Hyperglycaemia (DKA & HHS) 06-13 Toxicology 14-18 12 Lead ECG 19-21 Brain & Nervous System Anatomy & Physiology 22-24 Degenerative Neurological
NIH Public Access Author Manuscript J Magn Reson Imaging. Author manuscript; available in PMC 2011 June 1.
NIH Public Access Author Manuscript Published in final edited form as: J Magn Reson Imaging. 2010 June ; 31(6): 1469 1472. doi:10.1002/jmri.22192. Eccentric Target Sign in Cerebral Toxoplasmosis neuropathological
WSC , Conference 9. Case 1. Tissue from a rhesus macaque.
Case 1. Tissue from a rhesus macaque. MICROSCOPIC DESCRIPTION: Esophagus: There is multifocal loss of the mucosal lining (1 pt). In these areas, the denuded subepithelial fibrous connective tissue is infiltrated
Explain the laboratory diagnosis of Rabies?
Explain the laboratory diagnosis of Rabies? The standard test for rabies testing is dfa. This test has been thoroughly evaluated for more than 40 years, and is recognized as the most rapid and reliable
PRESERVE: How intensively should we treat blood pressure in established cerebral small vessel disease? Guide to assessing MRI scans
PRESERVE: How intensively should we treat blood pressure in established cerebral small vessel disease? Guide to assessing MRI scans Inclusion Criteria Clinical syndrome Patients must have clinical evidence
CNS TUMORS. D r. Ali Eltayb ( U. of Omdurman. I ). M. Path (U. of Alexandria)
CNS TUMORS D r. Ali Eltayb ( U. of Omdurman. I ). M. Path (U. of Alexandria) CNS TUMORS The annual incidence of intracranial tumors of the CNS ISmore than intraspinal tumors May be Primary or Secondary
2015 Descriptive Vet Path Course. Histo Exam #3 KEY
2015 Descriptive Vet Path Course Histo Exam #3 KEY Test 3, Slide 1 Tissue from a guinea pig. MORPHOLOGIC DIAGNOSIS: Heart: Multifocally and randomly (1 pt), within the left and right ventricular myocardium
Essentials of Clinical MR, 2 nd edition. 14. Ischemia and Infarction II
14. Ischemia and Infarction II Lacunar infarcts are small deep parenchymal lesions involving the basal ganglia, internal capsule, thalamus, and brainstem. The vascular supply of these areas includes the