CENTRO DI RIFERIMENTO ONCOLOGICO. I.R.C.C.S. CRO Aviano. 27 settembre 2018
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1 CENTRO DI RIFERIMENTO ONCOLOGICO I.R.C.C.S. CRO Aviano
2 NATIONAL CANCER INSTITUTE OF RESEARCH AND CARE Clinical and experimental activity based on research lines: 1. Tumor genetics and biology (basic and translational research) 2. Cancer epidemiology and prevention 3. Hematologic neoplasias, translational and clinical research 4. Solid tumors: from clinical-pathological databases to P4 medicine 5. Infectious agents associated tumors
3 1) BIOMEDICAL RESEARCH SCIENTIFIC PRODUCTION: articles published since opening IF >1000 GRANTS, last 3 years: Horizon (3 projects) Central Europe (patient education project) Italy-Austria (multicenter study on melanoma) NIH (sex hormone induced VTE) Ministry of University & Research and Ministry of Health (7 projects) Regional funds (14 projects) Italian Association for Cancer Research (15 projects)
4 2) PATIENT CARE patient exams per year 8295 admissions/year (50% extra-regional) for medium-long term stays and day hospital treatment All aspects of oncology. Particular emphasis on: Onco-Hematology, Breast Surgery, Onco-Geriatrics, Pharmacogenetics/genomics, Youth year olds (dedicated Radiation Therapy, Youth Area) Regional Cancer Register and Regional Biobank (leader of)
5 Endoscopic diagnosis by video capsule Linacs for IMRT and IORT, full brachytherapy, innovative Hi-Art Tomotherapy system Proton Therapy as new chance for pediatric and adolescent patients Radiopharmacy for research and diagnosis (radiolabelled isotopes) Qualifying Medical Technologies for Diagnosis and Treatment (examples) Combined PET/CT, image fusion for accurate diagnosis, staging, treatment planning Expression proteomics and functional proteomics to identify and characterize proteins in cancer with MALDI technique Facility of Flow Cytometry and Cell sorting NGS for high throughput analysis of the human genome Virtual microscopy and image analysis /quantitative pathology to characterize morphological and phenotypic features of neoplastic tissues
6 3) CROSS-DISCIPLINARY IN EDUCATION Model of community-based training and of interregional collaboration in medical education 150 clinical personnel (physicians, graduates), 485 technical and nursing staff, 80 support staff (clinical & research fellow trainees) Graduate Education: collaborations with universities CAMPUS: m² area providing: a) accommodation and logistics; b) spaces for teamwork, sharing of ideas, new projects
7 4) TECHNOLOGY TRANSFER AT CRO Pre-competitive projects with industry (13 ROP-ERDF grants) Growing portfolio of technology transfer opportunities 15 patented inventions from ideas of CRO researchers 6 licensing deals 4 spinoff companies Collaborations: S/T Parks (Pordenone, etc), NETVAL, grant from MISE
8 : T.T. as new indicator
9 Lessons learned - 1 Gonzalo Barrera Hernandez IP protection and exploitation: facts and myths, opportunities and risks SISSA, 2007
10 Lessons learned /2 Mark Coticchia, VP & CIO Henry Ford Health System keynote CRO MEETS INDUSTRY 2014 Creating innovation networks to grow bioindustry
11 THANK YOU FOR YOUR ATTENTION! Technology Transfer Office Ermes Mestroni
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