Wednesday 10/11. RNA: Transcription, splicing and Translation. G. Gick 9. Embryologic Basis of Congenital Dis.: Early Development. Eisner/ Lahage 108

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1 UNIT 2 DRAFT 2017 CALENDAR: Subunit 1: Molecular Cell Biology Monday 10/9 Tuesday 10/10 Wednesday 10/11 Version Thursday 10/12 Friday 10/13 Week 1 Total hrs = 18.5 Columbus Day Protein Trafficking W. Chirico 19 Non-Mendelian Inheritance N O Intro to Unit 2 IPAC Clinical Skills M.W. R. Ovitsh 6 DNA: Struct & Func of the Genome RNA: Transcription, splicing Translation G. Gick 9 Reg. of Gene Expression G. Gick 10 M. Feuerman 102 Signal transduction G. Gick 21 C L A S S E S M Feuerman 8 Cytoskeleton Cellular Motility J. Scalia 22 Cytogenetics M. Feuerman 139 Embryologic Basis of Congenital Dis.: Early Development Eisner/ Lahage 108 Proteins: Struct, Func, Folding I W. Chirico 5 Proteins: Struct, Func, Folding II W. Chirico 3 Mendelian Inherit., Pop. Genetics, Linkage Analysis M Feuerman 11 Enzymes: Classification, Energetics, Kinetics /Rushbrook 32 Embryologic Basis of Congenital Dis.: Musc./Skel System Eisner/Golden 109

2 UNIT 2 DRAFT 2017 CALENDAR: Subunit 2: Metabolism Week 2 Total hrs = 25.5 Monday 10/16 Tuesday 10/17 Wednesday 10/18 Thursday 10/19 Friday 10/20 Intro to Subunit 2 N. Intro to Path lab J. Libien 70 Session Adherence 38 LAB: Cell Injury & Tissue Damage Carbohydrate Metabolism 1 N. 143 Carbohydrate Metabolism 2 N. XXX Glycol. Glycog. & Lahage Half I N. N. 40 Oxidative Phosphorylation N. 42 Half 1 Multifactorial Inheritance Intro to Concepts in Nutrition M. Feuerman M. Markell 51 Mitochondria & the TCA Fat Absorption Cycle Transport M. Hussain 46 LAB: Cell Injury & Tissue Damage 100 Session Adherence 38 lab #3: Soc. Determ ts of Health (in Diabetes) 126A lab #3: Soc. Determ ts of Health (in Diabetes) 126B 121 lab #3: Soc. Determ ts of Health (in Diabetes) 126C lab #3: Soc. Determ ts of Health (in Diabetes) 126D 121 Half II N. 39 Glycol. Glycog. & Lahage Half 1 28 Fatty Acid Synthesis, Storage, & Oxidation M. Hussain 47 [132]: Stard Deviation/Frequency Distribution [132b} Std. Deviation P value [016] Nutrition: Self-Assessment 2

3 UNIT 2 DRAFT 2017 CALENDAR: Subunit 2: Metabolism Week 3 Total hrs = 24.5 Monday 10/23 Tuesday 10/24 Wednesday 10/25 Thursday 10/26 Friday 10/27 Amino Acid Metabolism I E. Quadros 53 Patient Perspective 45 Student Interviews of Simulated Patients Amino Acid Metabolism II E. Quadros 116 Errors in A. A Metab Quadros/ 52 Amino Acid Metabolism III E. Quadros XXX Reg of insul & gluca, gluco homeo H. Lebovitz 49 Urea Cycle / Quadros 54 sess N. Integrat. of Metab & Vitamins: pathways working together. 50 Markell/Feuerman 57 Pt. with Diabetes: Patient Perspective R. Ovitsh 114 Vesicular Trafficking W. Chirico students Cell Membranes 37 Sphingolipids & Lyso. Storage Diseases J. Rushbrook 43 Urea Cycle Patient Perspective 45 sess N. 50 / Quadros 54 Studetn SP Interviews 12 students [134]: Retrospective Cohort Confidence Interval [133a]: MM5 --- In Out of Network Care

4 UNIT 2 DRAFT 2017 CALENDAR: Subunit 3: Neoplasia Week 4 Total hrs = Mr. Palter 59 Introduction to Neoplasia 10/30 10/31 11/1 11/2 11/3 Intro. To Neoplasia Subunit Blain 93 J. Libien/J. Schneller Colon??? A. Leaf 91 Neoplasia I 75 Half 1 Neoplasia I 75 Half 2 Mr. Palter 59 Hallmarks of Cancer Blain Hallmarks 1 2: Prolif. of Cancer Cells independent of Growth Control Signals Blain 60 Skin B. Chaqour 104 Hallmark 4: Immortality, Altered Metab. & Genetic Instability of Cancer Cells Blain 90 Hallmark 3: Evading Apoptosis P. Bergold Skin B. Chaqour 104 Mr Palter Hallmark 5: Sustained Angiogenesis Mr Palter Hallmark 6: Tissue Invasion Metastasis 79 Linking Environmental Causes of Cancer to the Hallmarks Blain 74 [131]: Introduction to Screening [135]: Screening in Practice (Part 1) [135]: Screening in Practice (Part 2)

5 UNIT 2 DRAFT 2017 CALENDAR: Subunit 3: Neoplasia 11/6 11/7 11/8 11/9 11/10 Week 5 Total hrs = Veterans Day Neoplasia II Prevention Screening Basic Concepts in Dermatology Dr. S Glick 83 Guest Lecture: Mr. Rick Guidotti Director Positive Exposure XXX Mechanisms of carcinogenesis / Blain 118 Bone Cartilage Tumors Dr. V. Vigorita 120 Treatment of Cancer Hallmarks review Blain Mr. Palter sess Half I 5 th flr A Treatment of cancer / Blain 144 Hemoglobin Y. Zhang 18 Reg. of Hematopoiesis J. Gonsky 15 Prevention Screening 62 Neoplasia II 101 Lab #2: Dermatolo gy 128 Lab #2: Dermatolo gy 128 Mr. Palter sess 140 [136]: Number Needed to Screen [133b] MM5: Cost of Funding for Screening [137]: Prospective Cohort Case Control Studies

6 UNIT 2 DRAFT 2017 CALENDAR: Subunit 4: Hematology Intro to Human Development PBL Sm. Group T C Couple seeking Genetic Counseling 11/13 11/14 11/15 11/16 11/17 1 PBL Sm. Group T C Couple seeking Genetic Counseling 1 Evaluation of Anemia C. Luhrs 105 Fe Deficiency Excess C. Luhrs 107 Megalobl. Anemia Vit B12 & Folate C. Luhrs Hemostasis H static Disorders I Kang 23 Hemostasis H static Disorders II Kang 25 Hemoglobin O 2 Binding Y. Zhang 12 [138] Probability Part1 [138] Probability Part 2 [138] Probability Part Microcytic Macrocytic Anemia C. Luhrs 14 Theodora Charles Hemolytic Anemia C. Luhrs Theodora Charles Microcytic Macrocytic Anemia C. Luhrs 14 Hemostasis Kang Week 6 Total hrs = H. Huberman 92 Human Development: Newborn Infant H. Huberman 119 Lab #1: Human Develop. (Infant) 1.5 hr.'s/stude nt 122A Lab #1: Human Develop. (Infant) 1.5 hr.'s/stude nt 122B Hemoglobinopathies Y. Zhang

7 UNIT 2 DRAFT 2017 CALENDAR: Subunit 4: Hematology Week 7 Total hrs = 10.0 Monday Tuesday Wednesday Thursday 71 Friday 11/20 11/21 11/22 11/23 11/24 Approach to Clinical Reasoning Giuliano 165. Ethics Case??? 1 Hemo Anemia & Thrombocy topenia C. Luhrs Thrombosis Thrombotic Disorders 71 Thrombosis Kang Theodora Charles sess S t u d y Kang Hemo Anemia & Thrombocy topenia C. Luhrs. 24 Ethics case???? 1 Theodora Charles sess. D a y 71 4 [130]: MM4 Costs of Genetic Testing

8 UNIT 2 DRAFT 2017 CALENDAR: Subunit 5: Immune System its Malignancies Week 8 Total hrs = IL: Cultural Competence 11/27 11/28 11/29 11/30 12/1 T. Taylor 115 Culture & Medicine 55 Human Development: Toddler H. Huberman 112 Drug Receptor Interactions N. 113 Drug Metabolism & Pharmacogenetics P. Bergold 41 Pharmacokinetics of Asthma Treatment T. Sacktor/N. 68 Introduction to the Immune System. R. Coico XXX Components of the Immune system R. Coico XXX Assessment Week Overview Wagner, Ovitsh 84 Ig Genes, their Rearrangement, B Cell Development C. Roman XXX MHC Restriction Ag Presentation R. Coico XXX Pharmacokinetics Innate Immunity R. Coico XXX T Cell Development E. Hsu XXX T. Sacktor 67 Culture & Medic Lab #2 Human Developm ent (Toddler) 127 Lab #2 Human Developm ent (Toddler) Antibodies Antigens C. Roman XXX [066] Pharmacokinetics Problem Sets

9 UNIT 2 DRAFT 2017 CALENDAR: Subunit 5: Immune System its Malignancies Week 9 Total hrs = /4 12/5 12/6 12/7 12/8 POSSIBLE Q A (Survey students) XXX Lymphoid Neoplasms Primary lymphoid organs/peri p. bld. Smear B. Chaqour 155 T Cell Activation E. Hsu XXX B Cell Activation, Endstage Diff Ab Responses C. Roman XXX POSSIBLE Q A (survey students) Acute Myelogenous Leukemia XXX Secondary lymphoid organs/lym ph spln. Tons. B. Chaqour Lymphoid Neoplasms Student Interviews of Simulated Patients 56 students Primary lymphoid organs/peri p. bld. Smear B. Chaqour 155 Student SP Interviews 12 students 145 T Cell Effector Functions E. Hsu XXX Human Leuko Ags; ABO & Rh bld. grps. Kang 173 Myeloprolif. & Myelodyspl disorders I C. Luhrs 210 Myeloprolif. & Myelodyspl Disorders II C. Luhrs XXX Secondary lymphoid organs/lym ph spln. Tons. B. Chaqour Transplantation Immunology: Bone Marrow Transplant R. Coico / 175

10 UNIT 2 DRAFT 2017 CALENDAR: Subunit 5: Immune System its Malignancies Week 10 Total hrs = /11 12/12 12/13 12/14 12/15 Vulnerable Patient?????? 254 Lymphoid Neoplasms 171 Tutorial: Vulnerable Patient 157 Chemotherapeutics of Hemato. Malignan s I C. Luhrs 167 Chemotherapeutics of Hemato Malignan s II C. Luhrs 168 Special: Mult. Myeloma Patient Encounter 31 Immune Surveill. Mod. in Cancer Blain Leukemia Smears /Luhrs 208 S t u d y Tutorial: Vulnerable Patient 157 Lymphoid Neoplasms Leukemia Smears /Luhrs D a y Total hrs in unit = 200

11 UNIT 2 DRAFT 2017 CALENDAR Reflection, Integration & Assessment week Week 11 12/18 12/19 12/20 12/21 12/22 Clinical Skills Exams TBD Half II Combined Lab Practical 90 min () Half I Combined Lab Practical 90 min () Study Day Essay Exams 1 hour, 40 minutes Essay Exams 1 hour, 40 minutes After finishing your exam please log on to wbt.nbme.org/ex am follow instructions to access exam on your assigned computer. Please notify OAA if you have trouble accessing the exam via downstate to: Com-Exams NBME Exam 3 hours proper + 15 min orientation Multiple Choice Exam 1 hour, 20 minutes

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