Molecular Basis of Medicine (SMD 571) Class Schedule 2016
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1 Molecular Basis of Medicine (SMD 571) Class Schedule 2016 Week 1 Day 1 Monday, October 10 8:00-8:30 am Introduction / Onady Introduction Chemical Principles 8:30-9:30 am Introduction to Acid-Base Day 2 Tuesday, October 11 Amino Acids 10:00-10:30 am 10:30-11:30 am 11:30 am 12:00 pm Acid-Base Intro to Protein Structure Orientation Bring Clickers Protein Structure Biochemical Methods Trout Day 3 Wednesday, October 12 8:30-9:30 am Day 4 Thursday, October 13 Myoglobin Hemoglobin TBL Session 1: Acid Base Chemistry Plasma Proteins Fibrous Proteins Required : Chemical Principles 9/26/16 11:44 AM Required : ph; Acid-Base Dissociation of Chemical Functional Groups Required : Amino Acids Mandatory Required : Proteins Required : Proteins Coverage through: Biochemical Methods Required : Plasma Proteins Required : Connective Tissue and Fibrous Proteins Week 2 Day 5 Monday, October 17 i
2 Enzymes I & II 10:00 10:50 am Enzymes-Kinetics Day 6 Tuesday, October 18 Enzymes-Regulation 10:00-11:00 am Day 7 Wednesday, October 19 Nucleotides (purines) Nucleotides (pyrimidines) DNA Required : Enzymes Physical Properties, Coenzymes and Cofactors Coverage through: Fibrous Proteins Coverage through: Enzyme Regulation Required : Day 8 Thursday, October 20 9:00-9:30 am DNA 9:30-10:30 am DNA Replication TBL Session 2: Sickle Cell Anemia Week 3 Day 9 Monday, October 24 9:00-10:30 am Nucleotides, DNA & DNA Replication 10:45-11:35 am RNA and Transcription RNA and Transcription Day 10 Tuesday, October 25 Gene Regulation 10:00-10:45 am Gene Regulation Protein Synthesis TBL Session 3: Hyperuricemia Donnelly Protein Synthesis Genomic Rearrangements Day 11 Wednesday October 26 8:30 9:50 am 10:00 10:50 am : RNA, Transcription, Protein Synthesis & Genomic Rearrangements Mutation/DNA Repair Coverage: Nucleotides, DNA & DNA Replication Required : : Required : Required : Coverage: RNA, Transcription Protein Synthesis & Genomic Rearrangements ii
3 11:00 11:50 am Day 12 Thursday October 27 Week 4 Day 13 Monday, October 31 12:35 pm Doors Open 12:50 pm Ready to go EXAM 1 (coverage through 10/27/16) Day 14 Tuesday, November 1 Recombinant DNA Recombinant DNA/Clinical Molecular Genetics Clinical Molecular Genetics Amino Acid Metabolism Day 15 Wednesday, November 2 9:00-9:30 am Amino Acid Metabolism 9:40-11:10 am One-carbon Metabolism Day 16 Thursday, November 3 Aromatic Amino Acids and Biogenic Amines Heme Synthesis/Jaundice TBL Session 4: Xeroderma Pigmentosum Required : Required : Coverage: Amino acid metabolism Required : Required Week 5 Day 17 Monday, November 7 Introduction and Pedigree Construction Inheritance Patterns Cytogenetics I Day 18 Tuesday, November 8 Cytogenetics II Population Genetics Downs Syndrome Day 19 Wednesday, November 9 Biochemical Genetics iii
4 OTC Deficiency Cystic Fibrosis Day 20 Thursday, November 10 Multifactorial Inheritance/Cancer Genetics Cancer Genetics-Hereditary Breast and Ovarian Cancer Day 21 Friday, November 11 Cancer Genetics- Colon Cancer HNPCC TBL Session 5: Disorders of Amino Acid Metabolism Callif-Daley Veteran s Day University Closed Week 6 Day 22 Monday, November 14 Ehlers Danlos Syndrome Osteogenesis Imperfecta Prenatal Diagnosis Day 23 Tuesday, November 15 Introduction (Clickers); Overview of Carbohydrate Metabolism Important Chemical Structures Allsbrook Glycolysis Required : Glycolysis Day 24 Wednesday, November 16 Glycolysis Open Discussion 10:00-10:35 am TCA I 10:45-11:15 am Coverage through glycolysis 11:30 am 12:00 pm TCA II Required reading: Section 3 Day 25 Thursday, November 17 9:00 10:00 am Coverage through TCA 10:10 11:00 am Regulation of Metabolism I 11:10 11:40 am Regulation of Metabolism II; Shuttles TBL Session 6: Dietary Carbohydrate Metabolism iv
5 Gluconeogenesis & Pentose Phosphate Pathway Required : Sections 4 & 5 Week 7 Day 26 Monday, November 21 Coverage through PPP Coverage through PPP 11:00-11:30 am Ox. Phos. I Section 8 Gycogen Required : Section 7 Ox. Phos. II Required : Section Day 27 Tuesday, November 22 Day 28 Wednesday, November 23 8:35 am Doors Open 8:50 am Ready to go EXAM 2 Coverage through PPP Day 29 Thursday, November 24 THANKSGIVING BREAK Week 8 Day 30 Monday, November 28 Ox. Phos III Insulin Signaling I 11:00 am-12:00 Coverage through Ox. Phos. II Insulin Signaling II Required : Section Day 31 Tuesday, November 29 9:00-10:15 am Coverage through Insulin Signaling I 10:30-11:30 am Insulin Signaling III Day 32 Wednesday, November 30 Lipids/Introduction Fatty Acid Oxidation Fatty Acids/Ketone Bodies Day 33 Thursday, December 1 9:00-10:30 am Coverage through Ketone Bodies 10:40-11:05am 11:10-11:50 am Fatty Acid Synthesis Prostaglandins/Ecosanoids Required reading: Fatty Acid de novo synthesis/elongation/desaturation v
6 Week 9 Day 34 Monday, December 5 9:00 10:30 am Coverage through Ecosanoids 10:40 11:05am 11:15-11:50 am Cholesterol Synthesis Day 35 Tuesday, December 6 9:00-10:30 am 10:40-11:05 am Lipid Transport I 11:15-11:50 am Lipid Transport II Day 36 Wednesday, December 7 Triglycerides/complex Lipids Required reading: Complex lipids/membrane lipids and proteins Required : Membrane Lipid and Protein Through Cholesterol Synthesis Required reading: Bile Acids/digestion Atherosclerosis Required reading: Atherosclerosis TBL Session 7: Mechanisms of Diabetes Day 37 Thursday, December 8 8:15 9:00 am 9:00-10:00 am 10:00-10:45 am 10:45 11:30 am 11:30 am 12:00 pm Monday, December 12, EXAM :35 am Doors Open 8:50 am Ready to go vi
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