Wednesday, February 24 th, 2016

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2 List of Faculty: Nadeem R. Abu-Rustum, Giovanni Aletti, Istituto Europeo di Oncologia. Milan, Italy Natalia Carballo, Carlos Centeno, Clínica Universidad de Navarra. Pamplona, Spain David Cibula, General University Hospital in Prague, Charles University. Prague, The Czech Republic Robert L. Coleman, Nicoletta Colombo, Istituto Europeo di Oncologia. Milan, Italy Luis M. Chiva, Ben Davidson, The Norwegian Radium Hospital. Oslo, Norway Andreas du Bois, Kliniken Essen Mitte. Essen, Germany Pedro F. Escobar, Instituto Gyneco-Oncológico. San Juan, Puerto Rico Anna Fagotti, Catholic University of the Sacred Heart. Rome, Italy Michael M. Frumovitz, Juan Fernando García, David M. Gershenson, Antonio González-Martín, Anuja Jhingran, Matías Jurado, Clínica Universidad de Navarra. Pamplona, Spain Fernando Lapuente, Jonathan A. Ledermann, UCL Cancer Institute, University College. London, United Kingdom Mario M. Leitao, Karen H. Lu, Andrea Mariani, Mayo Clinic, Rochester. Minnesota, USA Christian Marth, Medical University Innsbruck, Austria Sergio Martínez, Hospital Clínic Universitari. Barcelona, Spain Ignacio Melero, Clínica Universidad de Navarra. Pamplona, Spain Mansoor R. Mirza, Rigshospitalet, Copenhagen University Hospital. Copenhagen, Denmark Gema Moreno, Ana Oaknin, Hospital General Vall d Hebron. Barcelona, Spain José Palacios, Hospital Universitario Ramón y Cajal. Madrid, Spain Sandro Pignata, National Cancer Institute Fondazione Pascale. Naples, Italy Jordi Ponce, Hospital Universitari de Bellvitge, L Hospitalet de Llobregat. Barcelona, Spain Andrés Poveda, Fundación Instituto Valenciano de Oncología. Valencia, Spain Eric Pujade-Lauraine, Hôpital Hôtel-Dieu. Paris, France Denis Querleu, Institut Bergonié. Bordeaux, France Pedro T. Ramirez, Andrés Redondo, Hospital Universitario La Paz. Madrid, Spain Ignacio Romero, Fundación Instituto Valenciano de Oncología. Valencia, Spain Anil Sood, Ate Van der Zee, University Medical Center of Groningen, Netherlands 12:00 12:15 WELCOME REMARKS DEALING WITH RARE OVARIAN TUMORS 12:15-12:35 Updates on novel therapies for rare tumors: From chemotherapy to innovative therapies Dr. David Gershenson 12:35-12:55 Overview of histopathologic classifications of rare tumors Dr. Juan Fernando García 12:55-13:20 Discussion 13:20-15:00 Lunch Moderator: KEYNOTE LECTURE 15:00-15:20 Hereditary cancer genetics in the era of targeted therapies Dr. Karen H. Lu Professor and Chair H.E.B. Professorship in Cancer Research Department Gynecologic Oncology & Reproductive Medicine 15:20-15:30 Discussion 15:30-16:00 INAUGURATION BY AUTHORITIES Wednesday, February 24 th, 2016

3 Wednesday, February 24 th, 2016 FROM LABORATORY MEDICINE TO INNOVATIVE CLINICAL APPLICATIONS: FOSTERING INNOVATION IN CONVERTING RESEARCH DISCOVERIES TO CLINICAL IMPACT Dr. Gema Moreno Dr. José Palacios Hospital Universitario Ramón y Cajal. Madrid, Spain Dr. Ignacio Romero Fundación Instituto Valenciano de Oncología. Valencia, Spain 16:00-16:20 Intra-tumor heterogeneity: Biological and clinical implications Dr. José Palacios Hospital Universitario Ramón y Cajal. Madrid, Spain 16:20-16:40 Gene panel testing in gynecological cancer: From the lab to the clinical practice Dr. Gema Moreno 16:40-17:00 Clinical implications of molecular analysis of serous effusions in ovarian cancer Dr. Ben Davidson The Norwegian Radium Hospital. Oslo, Norway 17:00-17:15 Discussion 17:15-17:45 Coffee break 17:45-18:05 Immunostimulatory monoclonal antibodies changing the landscape of gyn-cancer treatment Dr. Ignacio Melero Clínica Universidad de Navarra. Pamplona, Spain 18:05-18:25 Targeting angiogenesis in ovarian cancer: Overcoming adaptive responses Dr. Anil Sood 18:25-18:45 Harnessing homologous recombination deficiency for specialized treatment of ovarian cancer patients Dr. Robert L. Coleman 18:45-19:00 Endpoints in ovarian cancer trials: Insights from the 2015 SGO/ASCO/AACR FDA endpoints workshop Dr. Robert L. Coleman 19:00-19:15 Discussion INDIVIDUALIZING THERAPY IN ADVANCED OVARIAN CANCER Kliniken Essen Mitte. Essen, Germany Dr. Sergio Martínez Hospital Clínic Universitari. Barcelona, Spain 08:30-08:50 Assessment of quality in ovarian cancer surgery: The ESGO perspective Dr. Denis Querleu Institut Bergonié. Bordeaux, France 08:50-09:10 Laparoscopic evaluation to assess cytoreduction Dr. Anna Fagotti Catholic University of the Sacred Heart. Rome, Italy 09:10-09:30 Clinical and radiologic assessment of feasibility of cytoreduction Dr. Giovanni Aletti Istituto Europeo di Oncologia. Milan, Italy 09:30-09:50 Predictors of residual disease in patients with ovarian cancer Dr. Anil Sood 09:50-10:10 Adjuvant therapy in advanced ovarian cancer: Moving beyond carboplatin and paclitaxel Dr. Christian Marth Medical University Innsbruck, Austria 10:10-10:40 Discussion 10:40-11:10 Coffee break Thursday, February 25 th, 2016

4 INTEGRATING RECENT ADVANCES INTO OPTIMIZING TREATMENT FOR WOMEN WITH RECURRENT OVARIAN CANCER Dr. Andrés Poveda Fundación Instituto Valenciano de Oncología. Valencia, Spain Dr. Sandro Pignata National Cancer Institute Fondazione Pascale. Naples, Italy SENTINEL LYMPH NODE IN GYNECOLOGIC ONCOLOGY: A TIME TO SET NEW STANDARD OF CARE Dr. Jordi Ponce Hospital Universitari de Bellvitge, L Hospitalet de Llobregat. Barcelona, Spain Dr. Michael M. Frumovitz Dr. Pedro F. Escobar Instituto Gyneco-Oncológico. San Juan, Puerto Rico Thursday, February 25 th, :10-11:30 Selecting the really ideal patient for secondary cytoreduction Kliniken Essen Mitte. Essen, Germany 11:30-11:50 Chemotherapy in the recurrent ovarian cancer setting: Relying on the old standard or is novel therapy the new standard? Dr. Sandro Pignata National Cancer Institute Fondazione Pascale. Naples, Italy 11:50-12:10 Critical review of PARPi s in ovarian cancer therapy: How are we going to use them and when? Dr. Jonathan A. Ledermann UCL Cancer Institute, University College. London, United Kingdom 12:10-12:30 Integrating biological therapies in recurrent disease: Looking for the perfect algorithm Dr. Eric Pujade-Lauraine Hôpital Hôtel-Dieu. Paris, France 12:30-13:00 Discussion 13:00-14:40 Lunch 14:40-15:00 Cervical cancer: Can we stop performing complete lymphadenectomy? Dr. David Cibula General University Hospital in Prague, Charles University. Prague, The Czech Republic 15:00-15:40 Endometrial cancer: Memorial Sloan-Kettering vs. Mayo Clinic Dr. Nadeem R. Abu-Rustum Dr. Andrea Mariani Mayo Clinic, Rochester. Minnesota, USA 15:40-16:00 Vulvar cancer: Updates on current data and future trials Dr. Ate Van der Zee University Medical Center of Groningen, Netherlands 16:00-16:20 Discussion 16:20-16:40 Personalizing targeted therapy in advanced/metastatic cervical cancer: The challenge of anti-angiogenesis therapy Dr. Ana Oaknin Hospital General Vall d Hebron. Barcelona, Spain 16:40-16:50 Discussion 16:50-17:10 Coffee break Thursday, February 25 th, 2016

5 Thursday, February 25 th, 2016 UPDATES ON THE MANAGEMENT OF ENDOMETRIAL CANCER Dr. Natalia Carballo Dr. Andrés Redondo Hospital Universitario La Paz. Madrid, Spain Dr. Matías Jurado Clínica Universidad de Navarra. Pamplona, Spain 17:10-17:30 Current and future clinical trials in advanced/recurrent endometrial cancer Dr. Mansoor R. Mirza Rigshospitalet, Copenhagen University Hospital. Copenhagen, Denmark 17:30-17:50 Updates on standard care and novel approaches for radiation oncology in uterine cancer Dr. Anuja Jhingran 17:50-18:10 Reaching a consensus in endometrial cancer: European guidelines (ESGO-ESTRO-ESMO) Dr. Nicoletta Colombo Istituto Europeo di Oncologia. Milan, Italy 18:10-18:30 Discussion Moderator: PERSONALIZED MEDICINE IN GYNECOLOGIC ONCOLOGY: LOOKING BEYOND STANDARDS Dr. Karen H. Lu 08:30-08:45 Targeting stress neuroendocrine pathways in cancer Dr. Anil Sood 08:45-09:00 Enhance recovery after surgery (ERAS) 09:00-09:20 Impact of early integration of palliative medicine in the course of oncology treatment Dr. Carlos Centeno Clínica Universidad de Navarra. Pamplona, Spain 09:20-09:30 Discussion 09:30-10:45 TUMOR BOARD Panel: Dr. David Gershenson Dr. Karen H. Lu Dr. Nadeem R. Abu-Rustum Dr. Nicoletta Colombo Dr. Anuja Jhingran Dr. José Palacios Dr. Pedro F. Escobar Friday, February 26 th, 2016 Presenters: 1. Endometrial cancer with synchronous ovarian carcinoma? Dr. Nadeem R. Abu-Rustum 2. A challenging locally advanced cervical cancer, Dr. Fernando Lapuente 3. Serous carcinoma of the ovary in two different clinical scenarios

6 Friday, February 26 th, :45-11:15 MD ANDERSON SPAIN FOUNDATION AWARDS A life devoted to a great endeavour: Gynecologic oncology Kliniken Essen Mitte. Essen, Germany 11:15-11:45 Coffee break INNOVATIONS IN MINIMALLY INVASIVE SURGERY Dr. Michael M. Frumovitz 11:45-12:05 Update on robotic surgery in gynecologic oncology Dr. Mario M. Leitao 12:05-12:25 Role of single-port surgery by laparoscopy or robotics: Surgical innovation or a procedure without a future? Dr. Pedro F. Escobar Instituto Gyneco-Oncológico. San Juan, Puerto Rico 12:25-12:45 Discussion 12:45-13:45 SURGICAL FILM FESTIVAL Dr. Mario M. Leitao Dr. David Cibula General University Hospital in Prague, Charles University. Prague, The Czech Republic Laparoscopic contained power morcellation: techniques to avoid tumoral spread Dr. Ignacio Zapardiel, Dr. Javier De Santiago Hospital Universitario La Paz. Madrid, Spain Cytoreductive surgery of the upper abdomen and the diaphragm, with a plasma device surgery system, for advanced ovarian cancer Dr. Gloria Cordeiro, Dr. Babin Guillaume, Dr. Denis Querleu, Dr. Guyon Frédéric Institut Bergonié, Regional Comprehensive Cancer Center. Bordeaux-Aquitaine, France Cava vein injury during lymph node dissection Dr. Julián Di Guilmi, Dr. C. Darin, Dr. AG. Maya Hospital Británico de Buenos Aires, Argentina Sentinel node in vulva cancer Dr. Mario M. Leitao Modified rectus abdominis flap for pelvic floor reconstruction after exenteration Dr. David Cibula, Dr. M. Schneiderova, Dr. J. Slama, Dr. M. Zikan General University Hospital in Prague, Charles University. Prague, The Czech Republic 13:45-13:55 CLOSING REMARKS Ultra-radical laparoscopic abdominopelvic procedures Dr. Nicanor Barrena Pontificia Universidad Católica de Chile, Santiago de Chile Total pelvic exenteration plus IORT in recurrent cervical cancer Dr. Teresa Castellanos, Dr. Sonsoles Alonso, Dr. Fernando Lapuente, Vascular complication of left renal vein Dr. Carlos Millán Instituto Icera. Murcia, Spain Local Committee: Lucía Almeida Sonsoles Alonso Marisa Argente Elsa Bernal Raquel Bratos Natalia Carballo Teresa Castellanos Luis M. Chiva Virginia Corraliza Marta de la Fuente Irene Fernández Juan Fernando García Javier García Prado Antonio González-Martín Luis Granados Fernando Lapuente Pilar López Mendo Raúl Márquez Mar Mendivil Manuel Morales Gema Moreno Mª Jesús Pablos José Antonio Pérez Álvarez Gemma Toledo Covadonga Vidal

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