th International Charité Mayo Conference
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1 PREPUBLICATION SCIENTIFIC PROGRAM v 10 Global Perspectives and Future Directions in Women s Cancer April 3 6, 2019 Berlin th International Charité Mayo Conference CALL FOR ABSTRACTS
2 SCIENTIFIC PROGRAM WEDNESDAY, APRIL 3, 2019 BREAST CANCER 8.20 am Welcome Address of the Hosts J.-U. Blohmer, W. A. Cliby, 8.30 am LIVE SURGERY Moderation: J. Heil, S. Paepke Reduction Techniques, Lipofilling Techniques, Surgery of Lymphedema, Microanastomoses, Implant Based Reconstruction Surgeons: J.-U. Blohmer, O. Camara, S. Kümmel, R. Maatouk, C. Kolberg-Liedtke Lunch Break 1.30 pm Welcome Address Prof. Dr. med. Axel Radlach Pries, MD Dean, Charité Universitätsmedizin Berlin LECTURES AND PRO/CON SESSIONS Chair: U. Keilholz 1.35 pm Keynote Lecture: Outlook in the Therapy of Breast Cancer from a Translational Scientist s Point of View A. Lee Chair: O. Camara, S. Paepke 2.05 pm Locoregional Management of the Breast After Neoadjuvant Chemotherapy J. Heil 2.25 pm How to Avoid the Jumping Breast Phenomenon After Implant Reconstruction S. Kümmel 2.45 pm Reduction of Capsular Fibrosis Rate Using Meshes and Acellular Dermal Matrices? J.-U. Blohmer 3.05 pm Conservative Techniques for Treatment of Postoperative Lymphedema A. Reißhauer 3.25 pm Surgical Techniques for Treatment of Postoperative Lymphedema O. Camara 3.45 pm Coffee Break Chair: J.-U. Blohmer, C. Kolberg-Liedtke 4.15 pm Neoadjuvant Chemotherapy Why, When and How? L. Pusztai 4.45 pm Therapy of Triple Negative Breast Cancer C. Kolberg-Liedtke 5.00 pm Updates on Mechanisms of Endocrine Resistance S. Oesterreich 5.30 pm How to Avoid Adjuvant Over- or Undertherapy Using Molecular Tests O. Gluz 5.45 pm Early Recognition of Therapy Resistance by Patient Reported Outcome M. Karsten 6.00 pm Breast Cancer and Diabetes Mellitus N. V. Ivanov 6.20 pm Case Discussions i.a. on Biosimilars, Therapy Resistance, Immunology V. Kiver, M. Schubert, G. von Waldenfels 6.35 pm End of Program 4.00 pm to 6.00 pm parallel to main program INTENSIVE WORKSHOP OVARIAN CANCER Preoperative Management, Surgical, Anesthesiological and Perioperative Management, Surgical Techniques, ERAS and More ERAS, Prehabilitation M. Körber, R. Armbrust Opiate Reduction Perioperative/Opiate Crises S. C. Dowdy Indication, Contraindication, Techniques Cytoreductive Surgery, Middle and Lower Abdomen W. A. Cliby Cytoreductive Surgery, Upper Abdomen C. Fotopoulou limited number of participants extra charge only in combination with a conference ticket THURSDAY, APRIL 4, 2019 CERVICAL AND ENDOMETRIAL CANCER, RARE TUMORS 8.30 am LIVE SURGERY Moderation: W. A. Cliby, C. Marth, K. Pietzner Cervical, Endometrial and Vulvar Cancer, Exenteration, Complex Endometriosis Surgery Surgeons: V. Chiantera, S. Mahner, M. Z. Muallem, J. Neymeyer, during Live Surgery: The Most Challenging Case of the Year R. Chekerov Lunch Break LECTURES AND PRO/CON SESSIONS Cervical Cancer Chair: S. C. Dowdy, W. Lichtenegger 1.30 pm Pro/Con: Early Stage Cervical Cancer Is Minimal Invasive Surgery Harming? } Harming: D. Cibula } Not Harming: G. Scambia 2.10 pm Early stage Cervical Cancer } Trachelectomy or Cone Biopsy? N. R. Abu-Rustum } Current Aspects of Uterus Transplantation S. G. Tullius, G. Inci
3 SCIENTIFIC PROGRAM 2.50 pm Pro/Con: Locally Advanced Cervical Cancer } Primary Radio-Chemotherapy S. Marnitz-Schulze vs. } Primary Surgery M. Z. Muallem 3.30 pm Coffee Break Endometrial Cancer, Rare Tumors Chair: A. Poveda, P. Wimberger 4.00 pm Conservative Treatment of Early Stage Endometrial Cancer S. C. Dowdy 4.20 pm New Medical Therapies in Endometrial Cancer M. R. Mirza 4.40 pm Immunotherapy in Uterus and Cervical Cancer Where are We? J. S. Berek 5.00 pm Pro/Con: Molecular Profiling in Endometrial Cancer } Classical Histology N. Colombo vs. } Molecular Based Histology K. C. Podratz 5.40 pm Current Aspects of Surgical and Medical Therapies of Gynecological Sarcomas 5.55 pm Endometriosis and Gynecological Cancers: Etiology and Treatments S. Mechsner 6.10 pm End of Program 4.00 pm to 6.00 pm parallel to main program INTENSIVE WORKSHOP BREAST SURGERY Oncoplastic and Reconstructive Surgery Mesh, ADM, Lipofilling, Tumor Position Adapted Reduction and others J.-U. Blohmer, O. Camara, J. Heil, S. Kümmel, S. Paepke LECTURES AND PRO/CON SESSIONS Chair: L. Chiva, W. A. Cliby 1.30 pm HIPEC: Hype or Hope? C. Fotopoulou 1.50 pm Pro/Con: Surgery in Relapsed Ovarian Cancer } Pro: A. du Bois } Con: T. Herzog 2.30 pm Role of Lymph Node Dissection in Early, Low and High Grade Ovarian Cancer W. A. Cliby 2.50 pm Role of Lymph Node Dissection in Advanced Ovarian Cancer 3.10 pm Prediction of Surgical Outcome: Tumor Biology vs. Surgical Skills E. I. Braicu 3.30 pm Coffee Break Chair: A. González Martín, 4.00 pm PARP Therapies: Who are the Best Candidates and Who Not? J. Ledermann 4.20 pm Role of Antiangiogenesis in Gynecological Malignancies: Who are the Best Candidates and Who Not? S. Pignata 4.40 pm Low Grade Ovarian Cancer: Best Medical Treatment B. Monk 5.00 pm Immunotherapy in Ovarian Cancer: How to Optimize the Benefits O. Dorigo 5.20 pm New Targeted Therapies in Breast Cancer and Gynecological Cancers: Prevention and Management of Complication K. Pietzner 5.40 pm Similarities and Differences of Asian and Non-Asian Gynecological Cancer Patients K. Fujiwara 6.00 pm End of Program limited number of participants extra charge only in combination with a conference ticket FRIDAY, APRIL 5, 2019 OVARIAN CANCER 8.30 am LIVE SURGERY Moderation: A. du Bois, L. Chiva, B. Monk Ovarian Cancer and Sarcomas Surgeons: R. Chekerov, C. Fotopoulou, M. Z. Muallem, G. Scambia, during Live Surgery: The Most Challenging Case of the Year G. Inci Lunch Break SATURDAY, APRIL 6, 2019 SYMPOSIA IGCS PARSGO JOINED SYMPOSIUM Chair: T. Herzog, A. Poveda, 9.00 am How to Motivate Patients for Clinical Trials 9.30 am What are the Best Designs for Clinical Trials with Targeted Therapies? M. Bookman am How to Interpret Data Trials in Rare Tumors M. Seckl am Current and Future Aspects in Cervical Screening } The Turkish Experience: M. Gultekin } Global Perspectives: A. Kaufmann am Coffee Break
4 SCIENTIFIC PROGRAM SPEAKERS, SURGEONS, CHAIRS JOINED SYMPOSIUM: TOC, ENGOT, EUTROC, INTEGRATE Block I: Tailored Treatment of Ovarian Cancer Chair: E. I. Braicu, N. Concin am Early Stages: Is There a Signature that Can Predict Relapse? M. Birrer, H. Kulbe Can we Predict Response to Anti-Angiogenetic Drugs? C. Gourley Understanding PARPi Sensitivity or Addressing Platinum Sensitivity A. E. Wahner-Hendrickson Is there a Signature for Long-Term Survival with Ovarian Cancer? H. Woopen 1.00 pm Lunch Break + Poster Session Block II: Evidence Based and Personalized Medicine Complementary Approaches? Chair: C. Kolberg-Liedtke, C. Gourley 2.00 pm Options and Limits of New Generation Sequency for Treatment Selection M. Hummel 2.20 pm What are the Clinical Consequences of Tumor Profiling in Gynecological Oncology? D. Lorusso 2.40 pm Overcoming Endocrine Resistance in Hormone Receptor Positive Breast Cancer M. Liu 3.00 pm Role of PARP Therapies in Breast Cancer D. Speiser 3.20 pm Modifiers of Endocrine Resistance like CDK4/6 and PiK3CA Inhibitors: Who Benefits? J.-U. Blohmer 3.40 pm The Microbiome in Prediction of Cancer Therapy Response J. Grabowski 4.00 pm Closing Session Presentation of the Three Best Posters Closing Words and Farewell J.-U. Blohmer, W. A. Cliby, 9.00 am to am parallel to main program INTENSIVE WORKSHOP CERVICAL CANCER The Current Aspects of Cervical Cancer Therapy Early Cervical Cancer: How to Modify the Radicality? R. Querleu A Sentinel Lymph Node Mapping Algorithm N. R. Abu Rustum Nerve Sparing Radical Hysterectomy: Why? And Who are the Candidates? M. Z. Muallem limited number of participants extra charge only in combination with a conference ticket Abu-Rustum, Prof. Dr. Nadeem R., New York, NY (USA) Armbrust, Dr. med. Robert, Berlin (D) Berek, Prof. Dr. Jonathan S., Stanford, CA (USA) Birrer, Prof. Dr. Michael J., Birmingham, AL (USA) Blohmer, Prof. Dr. med. Jens-Uwe, Berlin (D) du Bois, Prof. Dr. med. Dr. h.c. Andreas, Essen (D) Bookman, Dr. Michael, San Francisco, CA (USA) Braicu, Prof. Dr. med. Elena Ioana, Berlin (D) Camara, Priv.-Doz. Dr. med. Oumar, Bad Langensalza (D) Chiantera, Prof. Dr. Vito, Palermo (I) Cibula, Prof. Dr. David, Praha (CZ) Chiva, Dr. Luis, Madrid (E) Cliby, Prof. Dr. William A., Rochester, MN (USA) Colombo, Prof. Dr. Nicoletta, Milano (I) Concin, Prof. Dr. Nicole, Innsbruck (A) + Leuven (B) Dorigo, Prof. Dr. Oliver, Stanford, CA (USA) Dowdy, Prof. Dr. Sean C., Rochester, MN (USA) Fotopoulou, Prof. Dr. med. Christina, Berlin (D) + London (UK) Fujiwara, Prof. Dr. Keiichi, Saitama (JP) Gluz, Priv.-Doz. Dr. med. Oleg, Mönchengladbach (D) González Martín, Dr. Antonio, Madrid (E) Gourley, Prof. Dr. Charlie, Edinburgh (UK) Grabowski, Dr. med. Jacek, Berlin (D) Gultekin, Prof. Dr. Murat, Ankara (TR) Heil, Prof. Dr. med. Jörg, Heidelberg (D) Herzog, Prof. Dr. Thomas, Cincinnati, OH (USA) Hummel, Prof. Dr. rer. nat. Michael, Berlin (D) Inci, Dr. med. Gülhan, Berlin (D) Ivanov, Prof. Dr. Nikita Vladimirovich, St. Petersburg (RUS) Karsten, Dr. med. Maria, Berlin (D) Kaufmann, Priv.-Doz. Dr. rer. nat. Andreas, Berlin (D) Keilholz, Prof. Dr. med. Ulrich, Berlin (D) Kiver, Verena, Berlin (D) Körber, Dr. med. Mareike, Berlin (D) Kolberg-Liedtke, Prof. Dr. med. Cornelia, Berlin (D) Kümmel, Prof. Dr. med. Sherko, Essen (D) Kulbe, Dr. med. Hagen, Berlin (D) Ledermann, Prof. Dr. Jonathan, London (UK) Lee, Prof. Dr. Adrian, Pittsburgh, PA (USA) Lichtenegger, Prof. Dr. med. Werner, Berlin (D) Liu, Dr. Minetta, Rochester, MN (USA) Lorusso, Dr. Domenica, Milano (I) Maatouk, Dr. Rabih, Mtayleb (LBN) Mahner, Prof. Dr. med. Sven, München (D)
5 SPEAKERS, SURGEONS, CHAIRS SOCIAL PROGRAM Marnitz-Schulze, Prof. Dr. med. Simone, Köln (D) Marth, Prof. Dr. med. Christian, Innsbruck (A) Mechsner, Prof. Dr. med. Sylvia, Berlin (D) Mirza, Dr. Mansoor Raza, København (DK) Monk, Prof. Dr. Bradley, Phoenix, AZ (USA) Muallem, Priv.-Doz. Dr. med. Dr. med. (syr) Mustafa Zelal, Berlin (D) Neymeyer, Dr. med. Jörg, Berlin (D) Oesterreich, Prof. Dr. Steffi, Pittsburgh, PA (USA) Paepke, Dr. med. Dipl.-Med. Stefan, München (D) Pietzner, Dr. med. Klaus, Berlin (D) Pignata, Dr. Sandro, Napoli (I) Podratz, Prof. Dr. Karl C., Rochester, MN (USA) Poveda, Prof. Dr. Andrés, Valencia (E) Pusztai, Prof. Dr. Lajos, New Haven, CT (USA) Querleu, Prof. Dr. Denis, Bordeaux (F) Reißhauer, Dr. med. Anett, Berlin (D) Scambia, Prof. Dr. Giovanni, Roma (I) Schubert, Dr. med. Melanie, Berlin (D) Seckl, Prof. Dr. Michael, London (UK) Sehouli, Prof. Dr. med. Jalid, Berlin (D) Speiser, Dr. med. Dorothee, Berlin (D) Tullius, Prof. Dr. Stefan G., Boston, MA (USA) Wahner-Hendrickson, Dr. Andrea E., Rochester, MN (USA) von Waldenfels, Dr. med. Gabriel, Berlin (D) Wimberger, Prof. Dr. med. Pauline, Dresden (D) Woopen, Dr. med. Hannah, Berlin (D) WELCOME EVENING Thursday, April 4, pm Hörsaalruine of the Medizinhistorisches Museum der Charité Campus Charité Mitte, Virchowweg 16 Evening reception Dress: formal Registration fee per person: EUR 20 More at: Æ Social Program limited number of participants only in combination with a conference ticket FESTIVE EVENING Friday, April 5, pm Clärchens Ballhaus Auguststraße 24, Berlin Evening reception and dinner Dress: formal Registration fee per person: EUR 50 More at: Æ Social Program limited number of participants only in combination with a conference ticket
6 GENERAL INFORMATION VENUE Langenbeck-Virchow-Haus Luisenstraße 58/ Berlin / Germany DATE April 3 6, 2019 SCIENTIFIC COMMITTEE Prof. Dr. med. Jalid Sehouli Department of Gynecology with Center for Oncological Surgery European Competence Center for Ovarian Cancer Charité Universitätsmedizin Berlin Campus Virchow-Klinikum Augustenburger Platz 1, Berlin / Germany Prof. Dr. med. Jens-Uwe Blohmer Department of Gynecology and Breast Center Charité Universitätsmedizin Berlin Campus Charité Mitte Charitéplatz 1, Berlin / Germany REGISTRATION FEES Total Conference Fee EUR 350 EUR 250 for members of AGO, NOGGO, PARSGO or ESGO and assistant physicians Day-Tickets EUR 130 per day EUR 100 per day for members of AGO, NOGGO, PARSGO or ESGO and assistant physicians Intensive Workshop Ovarian Cancer EUR 50 (additional charge) Intensive Workshop Breast Surgery EUR 50 (additional charge) Intensive Workshop Cervical Cancer EUR 50 (additional charge) Welcome Evening EUR 20 per person Festive Evening EUR 50 per person ORGANIZING COMMITTEE Prof. Dr. med. Jalid Sehouli Prof. Dr. med. Jens-Uwe Blohmer Prof. Dr. med. Elena Ioana Braicu Priv.-Doz. Dr. med. Dr. med. (syr) Mustafa Zelal Muallem Prof. Dr. William A. Cliby Mayo Clinic, Rochester MN / USA Prof. Dr. Sean C. Dowdy Mayo Clinic, Rochester MN / USA INFORMATION, ORGANIZER Jörg Eickeler Beratung Organisation Veranstaltung Neanderstraße Düsseldorf / Germany Tel. +49(0)211/ , Fax +49(0)211/ info@eickeler.org, HOMEPAGE REGISTRATION Online registration at: Preregistration deadline: March 29, 2019 Registration on site is possible. LIMITED NUMBER OF PARTICIPANTS The workshops and the evening events have a limited number of participants due to room capacity. ACCREDITATION CME-Points will be submitted at the Medical Association Berlin. The International Charité Mayo Conference in Berlin CALL FOR ABSTRACTS Poster Session Joined Symposium: TOC, ENGOT, EUTROC, INTEGRATE Saturday, April 6, 2019 DEADLINE: FEBRUARY 18, 2019 basic/translational science; predictive and prognostic biomarkers; gynecologic pathology and disease pathogenesis; breast cancer; cervical cancer; rare tumors and gestational trophoblastic neoplasia; ovarian cancer; uterine cancer including sarcoma; vulvar and vaginal cancer; surgical techniques and preoperative management; symptom management; palliation The Call for Abstracts also covers trials in progress abstracts. All phases of clinical research (phases I to III, supportive care, nonpharmacologic interventions) may be considered for inclusion in a trials in progress abstract submission. More at: Æ Call for Abstracts Status: December 2018 (subject to modification)
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