Here comes optional test menu for early detection of your diseases of concern!

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1 Lung Cancer in non-smoking person? One in 11 persons develops "Breast cancer? Here comes optional test menu for early detection of your diseases of concern! At Tokyo Midtown Clinic, we offer a wide variety of optional tests tailored to your specific needs with the help of cutting-edge medical technology. Please use the following information for detection of your diseases of concern and your personal heath management. Lung cancer screening The very first clinic in Japan to introduce CT machine with the newest technology CT scans provide more precise findings than conventional chest X-rays in the detection of lung cancer at an early stage. The mortality from lung cancer ranks first in Japanese men. It is difficult to get recognized at an early stage and can develop in both men and women, regardless of smoking habit. Our clinic is the first in Japan to introduce 80-slide helical CT scanner of the newest technology* which could provide more precise findings than conventional chest X-rays in the detection of lung cancer at an early stage. *As of June, 2017 Lung cancer screening (Helical Chest CT scan) 19,440 yen (Tax included) Required time: 10 minutes Breast cancer screening For women with dense breasts using the latest cutting-edge 3D mammography technology By reconstruction of three dimensional (3D) images from multiple views of breasts, 3D mammography can produce images of breast tumors including minute spots (micro calcifications), which are difficult to be detected by breast ultrasound or palpation, in greater clarity, making it useful for early detection of breast cancer. 2D 3D *Dense breast tissue refers to the appearance of breast tissues on a mammogram in which the percentage of glandular breast tissues is more than that of fatty tissues, and as a tumor lesion will appear white on a mammogram, it is difficult to differentiate from most of the solid white breast tissues, making tumor screening difficult. The prevalence of dense breast tissue is reported high in Asian women including Japanese. High resolution 3D technology helps visualize the breast lesions with greater clarity. Breast cancer screening (3D Mammography) 12,960 yen (Tax included) Required time: 15 minutes For those who already have made reservations for mammography examination, additional charge of 5,400 yen will be applied for examination with 3D mammography. With respect to age and individual conditions, breast ultrasound might be recommended for screening. Midtown Clinic Medical Corporation Executive Health Clinic / Health Screening Clinic Appointment by calling (9am to 5pm weekdays)

2 NEW No additional time required: Check your disease risks with blood testing. Allergy test Do you often have red eye, running nose, sneezing, cough or itchiness? These symptoms could be Signs of Allergy. Sometimes we are not aware of the presence of symptoms or do not give attention as the symptoms are mild, but those irritating symptoms could be the results of underlying allergic diseases. The symptoms could appear all of a sudden even in adults. It is important to know which are the causal agents for allergic reactions. This is the onestop test for 39 types of airborne and food allergies and a new test that could identify allergens most commonly seen indoors, plant pollens and seven mandatory items for food allergy labelling. Allergens tested Airborne allergens Indoor allergens (house dust, house mite), animals (cat and dog dander), insects (cockroach, moth), trees (cedar, cypress, alder, white birch), grass (orchard grass, timothy grass, ragweed, mugwort), airborne mold spores (sooty mold, aspergillus mold), yeast and others (candida, Malassezia species, latex) Food allergens Egg (egg white, ovomucoid), milk, wheat, legumes and cereals (soy, buckwheat, peanut, rice, sesame), shellfish (prawn, crab), fruits (kiwi, apple, banana), fish and meat (chicken, beef, pork, tuna, salmon, mackerel) Allergy Test (VIEW39) 15,120 yen (Tax included) No additional time required We do not provide consultation and treatment for allergic disorders. Please consult with the specialist in allergy and immunology for your results. Vitamin D deficiency test Overly restrictive UV exposure and unhealthy dieting might be related to increased risks of Cancer or Infertility Do you know that people nowadays might be in a state of vitamin D insufficiency? If we have adequate sun exposure even our diets are vitamin D insufficient, our body could produce enough vitamin D necessary for our health. But vitamin D insufficiency become prevalent in these days due to overly restrictive sun exposure and unhealthy dieting behavior. Vitamin D is necessary for bone health. There are recent reports that it may boost body immunity and protect against various diseases; and its deficiency could increase the risks for cancer and lifestyle related diseases as well as infertility, especially in women of reproductive age. Check your blood vitamin D level and take measures for your personal heath care. Vitamin D deficiency test 4,860 yen (Tax included) No additional time required Ovarian reserve test How is my ovarian reserve? What is my remaining reproductive lifespan? Recommended to those considering family planning This is the test to assess your ovarian age and remaining reproductive lifespan by testing Anti-Müllerian Hormone(AMH). The number of ovarian follicles are determined since birth and there is no formation of new follicles after birth. The follicles get fewer due to aging or ovulation and their quality can also be affected. There is individual variation in the condition of ovarian follicle. The earlier the family planning, the better it is for women to get tested. If you are considering about having a baby, testing is recommended at your earliest convenience. Ovarian reserve (Anti-Müllerian Hormone) test 7,560 yen (Tax included) No additional time required MTC

3 Tokyo Midtown Clinic Health Screening Center / Executive Health Center Option menu Reception hours (Weekdays) For prior reservation 9:00-17: This test item could be requested on your appointed screening day. You can check on the "Same-day Optional Exam Request Form" enclosed in the envelope and submit to the reception.

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6 Overseas shipping 2,160 yen (tax included) Image CD-ROM 1,080 yen (tax included) CD-ROM with imaging results will be enclosed with the report. It is useful for timely access to further care when retesting is decided necessary.