Interna'onal congress on Cancer cell death and resistance

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1 ! Interna'onal congress on Cancer cell death and resistance May 6 and 7, 2013 h"p://kcelldeath.sciencesconf.org Golf of Seilh Near to Toulouse (Midi-Pyrénées, 31, France)

2 Introduction Content : ² Introduction ² General presentation ² Program ² Committees ² Sponsors Resistance to an7- cancer regimens and to the immune system contributes to cancer progression and therapeu7c failure. The molecular mechanisms, which control the resistance of tumor cells towards the immune system and an7cancer therapies are not yet fully elucidated. A be"er knowledge of the signaling pathways involved in both phenomena should contribute to the development of novel an7- cancer therapeu7c strategies. Two recent scien7fic mee7ngs on cell death in oncology have been recently organized in France : The first mee7ng was a workshop in Dijon (Burgundy, France) organized by Dr. O. Micheau (INSERM UMR 866) in July This mee7ng was en7tled «Death- Domain- containing receptors and scaffold adaptors : fundamental and therapeu7c trails to cancer and immune diseases» (h"p://inserm- u866.u- bourgogne.fr/workshop Dijon/accueil_workshop.html). This workshop facilitated the mee7ng of about 50 French and interna7onal scien7sts and the establishment of collabora7ve projects. Thanks to the organiza7on commi"ee from Rennes (Bri"any, France) (Drs. P. Legembre, T. Guillaudeux, M.T. Dimanche- Boitrel) and the ac7ve par7cipa7on of scien7sts from different French laboratories, an interna7onal congress en7tled «Cell Death in cancer» was organized in May 2012 in St Malo (h"p:// This 4- day congress was very successful with 150 par7cipants, including pres7gious na7onal and interna7onal speakers. Taking into account the success of both scien7fic mee7ngs, the recurrent organiza7on of congress appears to be essen7al to structure the research on cell death in oncology in France. On May 6-7, 2013, we are organizing an interna7onal mee7ng on cancer cell death and resistance to be held at the Golf of Seilh, near to Toulouse- Blagnac Airport (France). Web site of the congress: h"p://kcelldeath.sciencesconf.org Web site of the hotel: h"p:// mercure- toulouse- golf- de- seilh/index.shtml

3 General Presentation Main topics of the congress : Apoptosis signaling and resistance : Novel molecular mechanisms modulating caspase activation and resistance of cancer cells. Alternative (non- apoptotic) cell death signaling pathways and resistance : Recently identified molecular pathways from different organelles (endoplasmic reticulum, Golgi apparatus, lysosome ), modulating cell death signaling in cancer cells. Cancer cell death and immune response : Modulation of the anti- cancer immune response by cell death. Resistance of cancer cells to the immune system. Main Objectives ü To mobilize the French and international scientific communities on the topic of cell death in oncology. ü To reinforce the dynamism of the French research in this competitive field by facilitating the establishment of a French network with diverse and complimentary expertise. ü To foster exchanges between young and senior scientists and favor collaborative, original and ambitious projects in the oncology field. Our Ambitions ü To propose prestigious seminars by famous international speakers. ü To propose oral and poster communications by young scientists. The congress will be organized in Toulouse with the participation of young and senior scientists from academic and private laboratories.

4 Scientific program May 6, 2013 : Cancer cell death and resistance am am : Registration and poster mounting am pm : Lunch buffet pm pm : Welcome session by the organizers (Dr. Nathalie Andrieu- Abadie, Prof. Thierry Levade and Prof. Bruno Ségui, Toulouse, France) pm pm : Introducing lecture by Prof. Henning Walczak (University College London, United Kingdom) pm pm : Coffee Break 3.30 pm pm : Session 1 : Apoptotic signaling and resistance Chairpersons: Dr. Catherine Pellat- Deceunynck (Nantes, France), Dr. Patrick Legembre (Rennes, France), Dr. Olivier Micheau (Dijon, France) 6 short oral communications (15 min. presentation and 5 min. discussion) to be selected by the scientific committee pm 7.30 pm : Poster session 1 visit of stands 8.00 pm : dinner May 7, 2013 : 8.30 am am : Session 2 : Alternative (non- apoptotic) cell death signaling and resistance. Chairpersons: Dr. Eric Chevet (Bordeaux, France), Dr. Jean- Ehrland Ricci (Nice, France), Dr. Philippe Juin (Nantes, France) 6 short oral communications (15 min. presentation and 5 min. discussion) to be selected by the scientific committee am am : Coffee Break am am: Seminar by Dr. Guillermo Velasco (Complutense University, Spain). Pivotal role of sphingolipids on the stimulation of autophagy- mediated cancer cell death by cannabinoids am am: Seminar by Prof. Toshiro Okazaki (Tottori University, Japan). The mechanism to overcome the chemo resistance of leukemia cells through autophagic cell death am pm : Poster Session 2 visit of stands 1.00 pm pm : Lunch 2.30 pm 4.30 pm : Session 3 : Cell death and immune responses Chairpersons: Dr. Frédéric Rieux- Laucat (Paris, France), Dr. Nicolas Bidère (Paris, France) 6 short oral communications (15 min. presentation and 5 min. discussion) to be selected by the scientific committee pm 5.00 pm: Coffee break 5.00 pm pm : Closing lecture by Dr. Pierre Golstein (Marseille- Luminy Immunology center, France). «Non- apoptotic cell death in a model organism» 5.45 pm: Conclusion End of the congress.

5 Committees Organiza'on Commi?ee: Prof. Bruno Ségui (INSERM UMR 1037, Toulouse, France) Prof. Thierry Levade (INSERM UMR 1037, Toulouse, France) Dr. Nathalie Andrieu- Abadie (INSERM UMR 1037, Toulouse, France) With the help of Mr. Sébas7en Guibert (INSERM UMR 1037, Toulouse, France) Mrs Marie- Angèle Albouy (Paul Saba7er University, Toulouse III, France) Scien'fic Commi?ee: Dr. Olivier Micheau (INSERM UMR 866, Dijon, France) Dr. Patrick Legembre (INSERM UMR 1085, Rennes, France) Dr. Frédéric Rieux- Laucat (INSERM UMR 768, Paris, France) Dr. Eric Chevet (INSERM 1053, Bordeaux, France) Dr. Nicolas Bidère (INSERM UMR 1014, Paris, France) Dr. Jean- Ehrland Ricci (INSERM 1065, Nice, France) Dr. Philippe Juin (INSERM UMR 892, Nantes, France) Dr. Catherine Pellat- Deceunynck (INSERM UMR 892, Nantes, France)

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