ODXJPVID July 2013
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1 SUMMER 2013
2 ODXJPVID July 2013
3 d e TABLE OF CONTENTS 1 History 2 in Brief 3 Routes of Vaccination 4 Instructions for Storage and Use of Vaccines 5 Precautions 6 List of s Large Animal Vaccines 6 Jovivac 6 Caprivac 6 Kenyavac 6 Pestevac 6 Orthovac 6 Anthravac 6 Bruce19vac 7 Brucevac (full dose) 7 Brucevac (reduced dose) 7 Brucevac (conjunctival) 7 lost 7 lost T 8 Black Quarter 8 Botivac 8 Jovapast 8 Jovaplasm C Poultry Vaccines 9 NDV B1 9 NDV Clone 9 NDV La Sota 9 NDV I2 9 IBD D78 9 IB H120 9 Combivac 9 Combivac C 9 Combivac L 9 Avipox 9 Gallovac 9R 10 Jova Zeit 1 10 Jova Zeit 1 Forte 10 Jova Zeit 1, 2 10 Jova Zeit 1, 3 10 Jova Zeit 1, 2, 4 10 Jova Zeit 4 10 Jova Zeit 1, 2, 3, 5 10 Jova Zeit 5 10 Jova Zeit 1, 6 11 Jova Zeit 7 11 Jova Zeit 1,7 11 Jovasalm E
4 1 2 history in brief was established in 1986 by The Government of the Hashemite Kingdom of Jordan with the assistance of the German Government through the GTZ. The main purpose for establishment is to prevent animal wealth losses through manufacturing veterinary vaccines and biological diagnostic reagents. is located in Yajouz forest, 10 miles north of Amman. In April 1997, was privatized with a capital of 2 million US$ keeping 20% of the shares for Jordan government. is committed to provide products that meet the demands of its customer all times all over the world. Therefore, we provide consistent quality products through the implementation of Good Quality Management System. Our products also con- form to Governmental Regulations and International Standards requirements (GMPs and GLPs) for manufacturing veterinary vaccines. These are implemented according to International Standards of OIE, FAO and WHO agencies to assure high quality and safe animal vaccines and biological products. The products are certified by International Reference Laboratories such as Paul Ehrlich Institute in Germany for (poultry vaccines), CNEVA/AFS- SA Laboratories in France (Brucella vaccines), Pirbright Laboratories in UK (pox vaccines), BGA Laboratories in Germany (Rose Bengal antigen) and Panvac Laboratories (FAO) in Ethiopia (PPR vaccine). Most of the vaccines master seeds used by are imported from international reference laboratories. Our laboratories are equipped with all necessary state-of-the-art high technology equipment for vaccine production and quality control testing. Bacterial and viral vaccines of large animals and poultry, together with ELISA kits, antigens, complements, and other biological materials are all produced by. A highly qualified team of experts with different specializations are responsible for the production and development of different vaccines and biological reagents. is commit- ted to continuous education and training to insure dynamic team and company progress. Today, provides to veterinary practitioners, large animal breeders and poultry breeders the finest products required for basic research and development. Now, we provide over 30 countries with series of high technology vaccines for poultry, cattle, sheep, goats, horses and camels together with biological diagnostic kits for animal disease diagnosis and control in order to improve animal health status and production parameters.
5 3 4 ROUTES OF VACCINATAION OCULAR NASAL ORAL Dissolve the vaccine in a physiological saline solution and administer by means of standardized dropper (usually 30 ml per 1000 doses). Place a drop of the vaccine solution in the eye of each bird. Wait until the drop spreads properly, and then free the bird. A drop of the vaccine is administered in the nostril; obstructing the other nostril with the finger to ensure that the nasal drop is inhaled by the bird. This route of vaccination is usually performed by reconstituting the vaccine with cool pure drinking water, free of antiseptics, and add to it powdered skimmed milk (2 g/l) to stabilize the vaccine s activity for a better virus protection. The temperature of the drinking water should not exceed 15 o C to 20 o C. Birds should be vaccinated by the oral route in the early morning because it is the main period of drinking. INSTRUCTIONS FOR STORAGE AND USE OF JOVAC VACCINES 1. Maintain cleanliness at all times. 2. Store vaccines according to instructions to retain their potency until the expiry date printed on the label. 3. Apply usual aseptic procedures for the preparation of the vaccinal solution. 4. The freeze-dried vaccine pellet should be reconstituted with the recommended diluent. 5. Once the bottle/vial is opened it must be used within 2-4 hours, any remains should be discarded properly. AEROGENIC WING-WEB INTRAMUSCULAR SUBCUTANEOUS The vaccine medicated water should be spread over the correct number of birds, from a distance of cm; preferably when birds are sitting together under dim light. Types of spray: -Coarse Spray Vaccination with coarse spray should be used in the first days of life. -Fine Spray Vaccination with fine spray should be only used for revaccinations and avoided in the first days of life. Dip the vaccination needle into the diluted vaccine vial and then puncture the unfledged skin of the wing. Only used with oil-based poultry vaccines. Inject the vaccine into the breast or thigh muscles in chickens. The vaccine is injected in front the point of the shoulder, in the Lower back part of the neck region, or in the elbow region of the animal. A subcutaneous injection is given by making a tent with the skin and injecting the solution under the fold of the skin, parallel with the muscle. The vaccine should be delivered slowly. 6. Administer the vaccine according to the provided instructions. 7. Use sterile syringes and needles, and handle them carefully with clean dry hands and replace the needles frequently. 8. Do not use chemicals for cleaning syringes and needles used for live vaccines. 9. Always observe the batch number and expiry date of the vaccine. Record vaccination date and details of any reaction observed. 10. Store the vaccines in the dark.
6 5 6 precautions LIST OF PRODUCTS 1. Do not vaccinate sick and/or under stress animals. 2. Bring the vaccine to room temperature before vaccination. 3. Consult your veterinarian to check the immune status of animals and birds prior to vaccination. 4. Rapid ocular administration of vaccine in birds may leave high percentages of unvaccinated birds. 5. For spray vaccination, the vaccine solution should be sprayed above the birds. Close windows and fans for 15 minutes while spraying. The spraying apparatus should be free from sediments, corrosion and traces of disinfectants. Aerosol generators should be used only when this is known to be safe to the birds. products are manufactured according to GMPs and GLPs requirments and many products were certified by the International Reference Laboratories. In 1997 introduced its first products into the Jordanian market and since then many products have been manufactured and developed to meet both local and international markets demands. Large animal vaccines Jovivac Caprivac At least TCID50 of freeze dried live attenuated Sheep Pox Virus strain RM-65. At least TCID50 of freeze dried live attenuated Goat Pox Virus strain Gorgan. Vials of 50, 100 and 200 Vials of 50 and For oral vaccination, deprive birds of drinking water 1-2 hours before vaccination, reconstitute the vaccine using cool drinking water that is free of chlorine and antiseptics. Adjust the amount of water to suit the age of the birds. 7. Vaccinated animals should be protected from stress factors. Kenyavac Pestevac At least TCID50 of freeze dried live attenuated Sheep Pox and Goat Pox Virus strain KSGP At least TCID50 of freeze dried live attenuated Peste Des Petits Ruminants (PPR) Virus strain Nig. 75/1. Vials of 100 Vials of 50 and Follow the instructions for proper handling and storage of vaccine carefully. Orthovac At least 8 x 10 6 TCID 50 of inactivated Camel Pox Virus vaccine strain Al Jouf-78. Bottle of 1, 2 and 5 9. Accidental inoculation of vaccine to human may result in local and systemic reaction. In case of accidental inoculation immediate medical attention must be seeked. Anthravac Bruce19vac At least 2-10x10 6 CFU Anthrax spores of encapsulated avirulent strain (Sterne 34F2) of high antigenic strength. At least X10 9 CFU viable organisms of freeze dried live attenuated Brucella abortus strain S19. Bottles of 50 and 100 ml. Vials of 1 and 2 Brucevac (full dose) At least X10 9 CFU viable organisms of freeze dried live attenuated Brucella melitensis strain Rev. 1. Vials of 10, 25 and 50
7 7 8 Brucevac (reduced dose) Brucevac (conjunctival) lost At least X10 5 CFU viable organisms of freeze dried live attenuated Brucella melitensis strain Rev. 1. At least X10 9 CFU viable organisms of freeze dried live attenuated Brucella melitensis strain Rev. 1. Polyvalent inactivated adjuvanated vaccine. Each 2 ml immunizing dose contains sufficient amount of toxoids and anacultures to obtain: Clostridium perfringens (types A, B, C and D) 0.3 IU of α antitoxin / ml of rabbit serum, 10 IU of ß antitoxin / ml of rabbit serum and 5 IU of ε antitoxin / ml of rabbit serum, Clostridium septicum 2.5 IU of antitoxin / ml of rabbit serum, Clostridium novyi (type A and B) 3.5 IU of antitoxin / ml of rabbit serum and Clostridium chauvoei 80% protection in guineapigs. Vials of 50 and 100 Vials of 25 and 50 Bottles of 50, 100, 250 and 500 ml. Botivac Bivalent inactivated adjuvanated vaccine. Each 2 ml immunizing dose contains sufficient amount of anacultures to obtain: Clostridium botulinum type C 80% protection in mice and Clostridium botulinum type D 80% protection in mice. Jovapast Jovaplasm C Polyvalent inactivated adjuvanated vaccine prepared from at least 7.0 x 10 9 CFU viable organisms of Pasteurella multocida serovars A and B and Pasteurella haemolytica serovars A1. At least 0.15 mg of inactivated Contagious Caprine Pleuropneumonia vaccine F38 biotype suspended in saponin. Bottles of 100 and 200 ml. Bottles of 50, 100, 200 and 250 ml. Bottles of 50 and 100 ml. lost T Polyvalent inactivated adjuvanated vaccine. Each 2 ml immunizing dose contains sufficient amount of toxoids and anacultures to obtain: Clostridium perfringens (types A, B, C and D) 0.3 IU of α antitoxin / ml of rabbit serum, 10 IU of ß antitoxin / ml of rabbit serum, 5 IU of ε antitoxin / ml of rabbit serum, Clostridium septicum 2.5 IU of antitoxin / ml of rabbit serum, Clostridium novyi (type A and B) 3.5 IU of antitoxin / ml of rabbit serum, Clostridium tetani 2.5 IU of antitoxin per ml of rabbit serum and Clostridium chauvoei 80% protection in guinea-pigs. Bottles of 50, 100, 250 and 500 ml. Black Quarter Monovalent inactivated adjuvanated vaccine. Each 2 ml immunizing dose contains sufficient amount of Clostridium chauvoei anacultures to induce 80% protection in guinea-pigs. Bottles of 100 and 200 ml.
8 9 10 Poultry vaccines NDV B1 At least EID50 of freeze dried live attenuated Newcastle Disease Virus strain Hitchner B1. Vials of 1000, 2500 and 5000 Jova Zeit 1 NDV Clone NDV La Sota NDV I2 IBD D78 At least EID50 of freeze dried live attenuated Newcastle Disease Virus strain Clone. At least EID50 of freeze dried live attenuated Newcastle Disease Virus strain La Sota. At least EID50 of freeze dried live attenuated Newcastle Disease Virus strain I2. At least TCID50 of freeze dried live attenuated Infectious Bursal Diseases Virus strain D78. Vials of 1000, 2000, 2500 and 5000 Vials of 200, 500, 1000, 2500 and 5000 Vials of 50, 100, 250, 500 and 1000 Vials of 500, 1000 and 2500 Jova Zeit 1 Forte Jova Zeit 1, 2 Jova Zeit 1, 3 Jova Zeit 1, 2, 4 At least EID50 of inactivated NDV. At least EID50 of inactivated IBV. At least EID50 inactivated NDV. At least TCID50 of inactivated IBDV. At least EID50 of inactivated IBV. At least 1000 HA units of inactivated EDS 76 virus. Bottle of 2500 IB H120 At least EID50 of freeze dried live attenuated Infectious Bronchitis Virus strain H120. Vial of 1000 Jova Zeit 4 At least 1000 HA units of inactivated EDS 76 virus. Combivac Combivac C Combivac L Avipox Freeze dried live attenuated vaccine which contains at least EID50 of Newcastle Disease Virus strain B1 and at least EID50 of Infectious Bronchitis Virus strain H120. Freeze dried live attenuated vaccine which contains at least EID50 of Newcastle Disease Virus strain Clone and at least EID50 of Infectious Bronchitis Virus strain H120. Freeze dried live attenuated vaccine which contains at least EID50 of Newcastle Disease Virus strain La Sota and at least EID50 of Infectious Bronchitis Virus strain H120. At least TCID50 of freeze dried live attenuated Fowl Pox Virus, strain HP-2. Vials of 1000 and 2500 Vials of 1000 and 2500 Vials of 1000 and 2500 Vials of 50, 100, 500 and 1000 Jova Zeit 1, 2, 3, 5 Jova Zeit 5 Jova Zeit 1, 6 Jova Zeit 7 At least EID50 of inactivated IBV. At least TCID50 of inactivated IBDV. At least TCID50 of inactivated Reo-virus. At least TCID50 of inactivated Reo virus. At least PFU of inactivated Adeno virus group 1 serotype 4. At least EID50 of inactivated Avian Influenza (subtype H9N2). Bottle of 2500 Gallovac 9R At least CFU, of freeze dried live attenuated Salmonella gallinarum strain 9R. Vials of 500 and 1000
9 11 12 Jova Zeit 1,7 Jovasalm E At least EID50 of inactivated Avian Influenza (subtype H9N2). At least 1X CFU of inactivated Salmonella enteritidis P.T.4. Bottles of 1000 and 2500 EID50: Egg Infective Dose 50. TCID50: Tissue Culture Infective Dose 50. PFU: Plaque Forming Unit. CFU: Colony Forming Unit. NDV: Newcastle Disease Virus. IBV: Infectious Bronchitis Virus. IBD: Infectious Bursal Disease Virus. EDS: Egg Drop Syndrome.
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