Eric Foster UCC Iowa City, IA (607) University of Iowa, Iowa City, IA July 2012 Ph.D.

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1 Eric Foster 2400 UCC Iowa City, IA (607) Education University of Iowa, Iowa City, IA July 2012 Ph.D., Biostatistics Dissertation Title: State-Space Time Series Clustering using Discrepancies based on the Kullback-Leibler Information and Mahalanobis Distance Advisor: Dr. Joseph E. Cavanaugh Rochester Institute of Technology, Rochester, NY May 2007 M.S., Bioinformatics Rochester Institute of Technology, Rochester, NY May 2007 B.S., Bioinformatics, Concentration in Economics Experience Clinical Assistant Professor Department of Biostatistics Clinical Trials Statistical and Data Management Center University of Iowa, Iowa City, IA July present Coordinating Center PI for the Clinical Islet Transplantation Consortium (Ongoing, Includes eight studies: 5 Phase II, 2 Phase III, and 1 long-term follow-up) Data Coordinating Center PI for Two NIH-funded Phase III Studies: BrAIST and CAPTION (Both have concluded) NeuroNEXT Design Team Lead (47 proposals have entered the network as of March 2017, 25 have been submitted to NIH, 8 have been funded with 2 more pending) Michael J. Fox Foundation Parkinson s Progression Markers Initiative Statistical Center Team Member (Ongoing) Visiting Assistant Professor August July 2013 Department of Biostatistics University of Iowa, Iowa City, IA Publications Polgreen, L.A., Anthony, C., Carr, L., Simmering, J.E., Evans, N.J., Foster, E.D., Segre, A.M., Cremer, J.F., Polgreen, P.M. (2018) The Effect of Automated Text Messaging and Goal Setting on Pedometer Adherence and Physical Activity in Patients with Diabetes, a Randomized Controlled Trial. PLOS ONE (in press) 1

2 Foster, E.D., Bridges, N.D., Feurer, I.D., Eggerman, T.L., Hunsicker, L.G., Alejandro, R., and the Clinical Islet Transplantation Consortium. (2018) Improved Health-Related Quality of Life in a Phase 3 Islet Transplantation Trial in Type 1 Diabetes Complicated by Severe Hypoglycemia. Diabetes Care Caspell-Garcia, C., Simuni, T., Tosun-Turgut D., Wu I.W., Zhang, Y., Nalls, M., Singleton, A., Shaw, L.A., Kang, J.H., Trojanowski, J.Q., Siderowf, A., Coffey, C., Lasch, S., Aarsland, D., Burn, D., Chahine, L.M., Espay, A.J., Foster, E.D., Hawkins, K.A., Litvan, I., Richard, I., Weintraub, D, and the Parkinson s Progression Markers Initiative. (2017) Multiple Modality Biomarker Prediction of Cognitive Impairment in Prospectively Followed de novo Parkinson Disease. PLOS ONE Zhang, Y., Wu, I.W., Tosun, D., Foster, E.D., Schuff, N. (2016) Progression of Regional Microstructural Degeneration in Parkinson s Disease: A Multicenter Diffusion Tensor Imaging Study. PLOS ONE Post, D.M., Ketterer, M.R., Coffin, J.E., Reinders, L.M., Munson Jr., R.S., Bair, T., Murphy, T.F., Foster, E.D., Gibson, B.W., and Apicella, M.A. (2016) Comparative Analyses of the Lipooligosaccharides from Nontypeable Haemophilus influenzae and Haemophilus haemolyticus Show Differences in Sialic Acid and Phosphorylcholine Modifications. Infection and Immunity Gums, T., Carter, B., Foster, E.D. (2016) Cluster Randomized Trials for Pharmacy Practice Research. International Journal of Clinical Pharmacy Thomann, M.A., Foster, E.D., Coffey, C.S. (2016) Exploring the Modification of Sample Size in Phase I Trials Using the Continual Reassessment Method on Proof-of-Concept During Drug Development. Applied Stochastic Models and Data Analysis International Conferences, Meetings and Publications Schuff, N., Wu, I.W., Buckley, S., Foster, E.D., Coffey, C.S., Gitelman, D.R., Mendick, S., Seibyl, J., Simuni, T., Zhang, Y., Jankovic, J., Hunter, C., Tanner, C.M., Rees, L., Factor, S., Berg, D., Wurster, I., Gauss, K., Sprenger, F., Seppi, K., Poewe, W., Mollenhauer, B., Knake, S., Mari, Z., McCoy, A., Ranola, M., Marek, K. (2015) Diffusion Imaging of Nigral Alterations in Early Parkinson s Disease with Dopaminergic Deficits. Movement Disorders Zhang, Y., Wu, I.W., Buckley, S., Coffey, C.S., Foster, E.D., Mendick, S., Seibyl, J., and Schuff, N. (2015) Diffusion Tensor Imaging of the Nigrostriatal Fibers in Parkinson s Disease. Movement Disorders Anthony, C.A., Polgreen, L.A., Chounramany, J., Foster, E.D., Goerdt, C.J., Miller, M.L., Suneja, M., Segre, A.M., Carter, B.L., and Polgreen, P.M. (2015) Outpatient Blood Pressure Monitoring Using Bi-directional Text Messaging. Journal of the American Society of Hypertension Weintraub, D., Simuni, T., Caspell-Garcia, C., Coffey, C., Lasch, S., Siderowf, A., Aarsland, D., Barone, P., Burn, D., Chahine, L.M., Eberling, J., Espay, A.J., Foster, E.D., Leverenz, J.B., Litvan, I., Richard, I., Troyer, M.D., Hawkins, K.A., and PPMI (2015) Cognitive Performance and Neuropsychiatric Symptomes in Early, Untreated Parkinsons Disease. Movement Disorders 2

3 Cho, C., Chande, A., Gakhar, L., Bakaletz, L.O., Jurcisek, J., Ketterer, M., Shao, J., Gotoh, K., Foster, E.D., Hunt, J., O Brien, E., Apicella, M.A. (2015) Role of the Nuclease of Nontypeable Haemophilus influenzae in Dispersal of Organisms from Biofilms. Infection and Immunity Gerke, A.K., Yang, M., Tang, F., Foster, E.D., Cavanaugh, J.E., and Polgreen, P.M. (2014) Association of Hospitalizations for Asthma with Seasonal and Pandemic Influenza. Respirology Fairchild, G., Polgreen, P.M., Foster, E.D., Rushton, G., and Segre, A.M. (2013) How Many Suffice? A Computational Framework for Sizing Sentinel Surveillance Networks. International Journal of Health Geographics Gerke, A.K., Tang, F., Yang, M., Foster, E.D., Cavanaugh, J.E., and Polgreen, P.M. (2013) Predicting Chronic Obstructive Pulmonary Disease Hospitalizations Based on Concurrent Influenza Activity. COPD: Journal of Chronic Obstructive Pulmonary Disease *Poole, J., Foster, E.D., Chaloner, K., Hunt, J., Jennings, M.P., Bair, T., Knudtson, K., Christensen, E., Munson Jr., R.S., Winokur, P.L., and Apicella, M.A. (2013) Analysis of Nontypeable Haemophilus influenzae Phase-Variable Genes During Experimental Human Nasopharyngeal Colonization. Journal of Infectious Diseases Foster, E.D., Cavanaugh, J.E., Haynes, W.G., Yang, M., Gerke, A.K., Tang, F., and Polgreen, P.M. (2013) Acute Myocardial Infarctions, Strokes and Influenza: Seasonal and Pandemic Effects. Epidemiology and Infection Foster, E.D. and Cavanaugh, J.E. (2012). Composite Marginal Discrepancies for State-Space Time Series Clustering. Mathematics in Engineering, Science and Aerospace Sharma, D., Thomas, G.W., Foster, E.D., Iacovelli, J., Lea, K.M., Streit, J.A., and Polgreen, P.M. (2012) The Precision of Human-Generated Hand-Hygiene Observations: A Comparison of Human Observation with an Automated Monitoring System. Infection Control and Hospital Epidemiology Ebert, S.M., Dyle, M.C., Kunkel, S.D., Bullard, S.A., Bongers, K.S., Fox, D.K., Dierdorff, J.M., Foster, E.D., Adams, C.M. (2012) Stress-Induced Skeletal Muscle Gadd45a Expression Reprograms Myonuclei and Causes Muscle Atrophy. The Journal of Biological Chemistry Foster, E.D., Yang, M., Polgreen, P.M., and Cavanaugh, J.E. (2011) A Time Series Analysis to Investigate the Relationship Between Acute Myocardial Infarction Incidence and Influenza Activity. Biometrie und Medizinische Informatik Greifswalder Seminarberichte * Co-first author Presentations Foster, E.D. and Caspell, C. (2016). PPMI Data Access. Michael J Fox Foundation Parkinson s Progression Markers Initiative Annual Meeting, New York, New York. Foster, E.D. (2015). Using Concurrent Placebo Subjects in Dose-Finding Studies. ASMDA, Athens, Greece. (Invited, July 2015). 3

4 Foster, E.D. (2015). Uncertainty in the Target Toxicity Level in Dose Finding Studies. Society for Clinical Trials, Arlington, Virginia. (Contributed, May 2015). Foster, E.D. (2015). NeuroNEXT Experiences in the Pre-Grant Process. Society for Clinical Trials, Arlington, Virginia. (Contributed, May 2015). Foster, E.D. and Caspell, C. (2015). PPMI Data Access. Michael J Fox Foundation Parkinson s Progression Markers Initiative Annual Meeting, New York, New York. Foster, E.D. and Coffey, C.S. (2014). Challenges in Designing Clinical Trials for Rare Diseases. Joint Statistical Meetings, Boston, Massachusetts. (Contributed, August 2014). Foster, E.D. and Cavanaugh, J.E. (2013). State-Space Time Series Clustering Using Discrepancies Based on the Kullback-Leibler Information and the Mahalanobis Distance. Joint Statistical Meetings, Montreal, Canada. (Contributed, August 2013). Foster, E.D. and Cavanaugh, J.E. (2012). State-Space Time Series Clustering Using Discrepancies Based on the Kullback-Leibler Information and the Mahalanobis Distance. International Conference on Nonlinear Problems in Aviation and Aerospace 2012 Congress, Vienna, Austria. (Invited, July 2012). Foster, E.D. and Cavanaugh, J.E. (2012). State-Space Time Series Clustering Using Discrepancies Based on the Kullback-Leibler Information and the Mahalanobis Distance. Eastern North American Region of the International Biometric Society Spring Meeting, Washington D.C. (Contributed, Apr. 2012). Foster, E.D., Cavanaugh, J.E., and Polgreen, P.M. (2011). Clustering of U.S. Cities Based on Mortality from Influenza and Pneumonia. International Society for Disease Surveillance Conference, Atlanta, Georgia. (Contributed, Dec. 2011). Posters Foster, E.D., Mahoney, K., Ecklund, D., Kearney Chase, M., Bosch, M., Thornell, B., Coffey, C., and Cudkowicz, M. (2017) Network for Excellence in Neuroscience Clinical Trials, NeuroNEXT: Pre-Award Process and Experiences. Society for Clinical Trials, Liverpool, England. (Contributed, May 2017). Teaching BIOS:5310 Research Data Management Spring 2018 BIOS:5310 Research Data Management Spring 2016 BIOS:6610 Statistical Methods in Clinical Trials Spring 2015 BIOS:6610 Statistical Methods in Clinical Trials Spring 2014 BIOS:5110 Introduction to Biostatistics Spring 2013 BIOS:7600 Advanced Biostatistics Seminar - Statistics in Microbiology Sub-Lecturer Fall 2010 BIOS:5310 Research Data Management Team Teacher Fall 2009 (Primary instructor unless otherwise noted) 4

5 PhD Advisees *Mitchell A. Thomann Dissertation Title: The Flexibile Bivariate Continual Reassessment Method * Co-advised Service Department of Biostatistics Awards Committee Member NINDS Clinical Trials Methodology Course Course Faculty Department of Biostatistics Admissions Committee Co-Chair Department of Biostatistics Admissions Committee Member present present present present College of Public Health Faculty Council Member Encyclopedia Entries Cavanaugh, J.E. and Foster, E.D. Odds. In Encyclopedia of Research Design, edited by N. Salkind. Sage Publications, Thousand Oaks, California, Cavanaugh, J.E. and Foster, E.D. Margin of Error. In Encyclopedia of Research Design, edited by N. Salkind. Sage Publications, Thousand Oaks, California, Cavanaugh, J.E. and Foster, E.D. Likelihood Ratio Statistic. In Encyclopedia of Research Design, edited by N. Salkind. Sage Publications, Thousand Oaks, California, Book Reviews Foster, E.D. (2008). Review of Introduction to Bioinformatics, by Tramontano, A. The American Statistician, 62.3, Journal Reviews Referee for Stochastic Environmental Research and Risk Assesment. Referee for Annals of Epidemiology. Organizations Member of the American Statistical Association. April present. Member of the Society of Clinical Trials. August present. 5

6 Awards College of Public Health Faculty Teaching Award, 2017, University of Iowa. Department of Biostatistics Leon J. Burmeister Graduate Student Service Award, 2012, University of Iowa. University-wide Outstanding Teaching Assistant Award, 2010, University of Iowa. 6