Clinical Conference, continued

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1 Clinical Conference, continued James H. Philip, M.E.(E.), M.D., CCE Anesthesiologist and Director of Anesthesia Technology, Brigham and Women's Hospital Associate Professor of Anaesthesia, Harvard Medical School Medical Liaison, Partners Biomedical Engineering Copyright 2004, James H. Philip MD, all rights reserved.

2 Technology Lectures are available on BWH Anesthesia www home page

3 2 Education

4 3 Educational Resources

5 4 Lectures and Presentations

6 Case 2 - at EGH Healthy 45 yo F scheduled for diagnostic pelvic laparoscopy She had an uneventful anesthetic from same anesthesiologist at BWH 3 months ago IV Propofol seems to have lesser effect than at BWH Slower onset Smaller peak effect What could the difference be

7 Difference in drug effect

8 Difference in drug effect Patient same patient Drug composition Propofol source Propofol mixing, dilution, age Drug delivery

9 Arrow (Company) Walrus (Brand) In-Line Gravity-Pressure Check Valve One way valve Points to patient Opening Pressure Less than 1 cm H 2 O

10 Drug back up in IV tubing Check Valve (One way valve) blocks reverse flow No need to turn stopcock during injection Unless there is no one way valve

11 Stopcock IV Bag Patient

12 Stopcock IV Bag Patient

13 Stopcock IV Bag Patient

14 Swabbable Connector All injection ports Except Stopcocks

15 Walrus Anesthesia IV Set Cardinal Health - Alaris SmartSite

16 Swabbable Connector, another

17 Connect tubing Always Luer Lock Swabbable Connector, another

18 CLAVE Swabbable Connector Connect syringe Always Luer Lock

19 CLAVE -like Connector opened

20 CLAVE Swabbable Connector

21

22 Case 3 - at BWH Same patient Healthy 45 yo F scheduled for diagnostic pelvic laparoscopy BWH this time IV Propofol has strange effect Slow onset Big peak effect, late What could the difference?

23 Backup into piggy-back bag No check valve On standard IV Sets

24 Check Valves are available

25 Check Valves are available

26 Walrus Gravity-Operated Check Valve

27 Walrus Gravity-Pressure Check Valve

28 Check Valves are available

29 Walrus Wide Bore Stopcock

30 Another Case?

31 Another IV Drug failure 45 yo M for Open Cholecystectomy Twitches came and went throughout case with Vecuronium Tx Near the end of the case, there is no response to nerve stimulator Electrodes are in ulnar groove on Left Arm IV is in left arm, BP Cuff is on Right Arm Suddenly the patient moves dramatically and the surgical exposure is lost What s wrong?

32 Occasional Vecuronium, Monitored with PNS

33 Occasional Vecuronium, Monitored with PNS

34 Manipulation of lead connections Output is intermittent Between Zero And a Good Value.

35 Lead Connections New problem in past few years FDA mandated recessed female connections on all patient leads Prevents someone from plugging leads into a wall outlet with 120 V AC Feels like the connection is made Plastic on plastic Conceals lack of connection

36 Manipulation of lead connections Check current delivered Two electrodes can be connected together To test the current delivered Or, look at # when stimulating

37 Rare problems observed

38 Inverted Valve Walrus Gravity-Pressure Check Valve Installed upside down Total Occlusion Note valve flow is White to Clear

39 Crushed Tubing Walrus Tubing crushed in manufacture or shipping Total Occlusion

40 Occluded channel Walrus Luer Connector Sealed shut Total Occlusion

41 Thank you

42 TECHNOLOGY BLOCK Lectures are on Anesthesia Department Web Site Home Education Education Resources Lectures

43 4 Lectures and Presentations TECHNOLOGY BLOCK Lectures are on Anesthesia Department www home page Home Education Education Resources Lectures

44 Thank you

45 End

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