BRITISH REGIONAL HEART STUDY PUBLICATIONS

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1 1980 Pocock SJ, Shaper AG, Cook DG, Packham RF, Lacey RF, Powell P et al. British Regional Heart Study: geographic variations in cardiovascular mortality, and the role of water quality. BMJ 1980; 280 (6226): Shaper AG, Packham RF, Pocock SJ. The British Regional Heart Study: cardiovascular mortality and water quality. Journal of Environmental Pathology & Toxicology 1980; 4(2-3): Cummins RO, Shaper AG, Walker M, Wale CJ. Smoking and drinking by middle-aged British men: effects of social class and town of residence. BMJ 1981; 283(6305): Cummins RO, Shaper AG, Walker M. Methodological problems with estimation of salt intake (letter). Lancet 1981; 1(8234): Masironi R, Shaper AG. Epidemiological studies of health effects of water from different sources. Annual Review of Nutrition 1981; 1: Pocock SJ, Shaper AG, Packham RF. Studies of water quality and cardiovascular disease in the United Kingdom. Science of the Total Environment 1981; 18: Pocock SJ, Cook DG, Beresford SAA. Regression of area mortality rates on explanatory variables: What weighting is appropriate? The Journal of the Royal Statistical Society 1981; 30(3): Shaper AG, Pocock SJ, Walker M, Cohen NM, Wale CJ, Thomson AG. British Regional Heart Study: cardiovascular risk factors in middle-aged men in 24 towns. BMJ 1981; 283(6285): Cook DG, Cummins RO, Bartley MJ, Shaper AG. Health of unemployed middle-aged men in Great Britain. Lancet 1982; 1(8284): Cripps P. Alcohol and disease: an investigation into the health of non-drinkers. Thesis: MSc University of London. Cummins RO, Cook DG, Hume RC, Shaper AG. Tranquillizer use in middle-aged British men. Journal of the Royal College of General Practitioners 1982; 32(245): Pocock SJ, Cook DG, Shaper AG. Analysing geographic variation in cardiovascular mortality: Methods and results. The Journal of the Royal Statistical Society 1982; 145(3): Shaper AG, Pocock SJ, Walker M, Wale CJ, Clayton B, Delves HT et al. Effects of alcohol and smoking on blood lead in middle-aged British men. BMJ 1982; 284(6312): Broughton PMG, Holder R, Anglesea J. Long term trends in biochemical data. In Proceedings of the Medinfo 83 Seminars. Editor: Fokkens O. 1983; Cook DG, Pocock SJ. Multiple Regression in geographical mortality studies, with allowance for spatially correlated errors. Biometrics 1983; 39(2): Pocock SJ, Shaper AG, Walker M, Wale CJ, Clayton B, Delves T et al. Effects of tap water lead, water hardness, alcohol, and cigarettes on blood lead concentrations. Journal of Epidemiology & Community Health 1983; 37(1): 1-7. Shaper AG, Pocock SJ, Packham RF, Lacey RF, Powell P. Softness of drinking water and cardiovascular disease - practical implications of recent research. Health Trends 1983;15: Thelle DS, Shaper AG, Whitehead TP, Bullock DG, Ashby D, Patel I. Blood lipids in middle-aged British men. British Heart Journal 1983; 49(3):

2 1984 Ashby D. A Statistical investigation of the relationship of serum biochemistry and haematology to alcohol consumption. Thesis: PhD University of London. Cook DG, Shaper AG. Unemployment and health. In Recent Advances in Occupational Health. Editors: Harrington, J. M. Publishers: Churchill Livingstone, London 1984; Chapter 18, Kussick S. The prevalence of chronic bronchitis in a cohort of 7735 middle-aged British men. Thesis: MSc University of London. Pocock SJ, Shaper AG, Ashby D, Delves T, Whitehead TP. Blood lead concentration, blood pressure, and renal function. BMJ 1984; 289(6449): Shaper AG, Cook DG, Walker M, Macfarlane PW. Recall of diagnosis by men with ischaemic heart disease. British Heart Journal 1984; 51(6): Shaper AG, Cook DG, Walker M, Macfarlane PW. Prevalence of ischaemic heart disease in middle aged British men. British Heart Journal 1984; 51(6): Shaper AG. Geographic variations in cardiovascular mortality in Great Britain. [Review]. British Medical Bulletin 1984; 40(4): Walker M, Shaper AG. Follow-up of subjects in prospective studies based in general practice. Journal of the Royal College of General Practitioners 1984;34(264): Cook DG. A critical view of the unemployment and health debate. The Statistician 1985;34(1): Pocock SJ, Shaper AG, Ashby D, Delves HT. Blood lead and blood pressure in middle-aged men. In Lead Environmental Health - The Current Issues. Publishers: Division of Occupational Medicine Duke University, Durham North Carolina, USA. 1985; Pocock SJ, Shaper AG, Powell P. The British Regional Heart Study: cardiovascular disease and water quality. In Drinking Water and Cardiovascular Disease. Publishers: Water Research Centre, Marlow, England. 1985; Chapter 12: Shaper AG, Pocock SJ. British blood cholesterol values and the American consensus [letter]. British Medical Journal 1985;291(6493): Shaper AG, Pocock SJ, Ashby D, Walker M, Whitehead TP. Biochemical and haematological response to alcohol intake. Annals of Clinical Biochemistry 1985;22 (1): Shaper AG, Pocock SJ, Walker M, Phillips AN, Whitehead TP, Macfarlane PW. Risk factors for ischaemic heart disease: the prospective phase of the British Regional Heart Study. Journal of Epidemiology & Community Health 1985; 39(3): Shaper AG, Pocock SJ. Blood lead and blood pressure [editorial]. British Medical Journal 1985; 291(6503): Walker M. A comparative study of non-responders and responders in health research. Thesis: MA University of Leeds Ashby D, Pocock SJ, Shaper AG. Ordered polytomous regression: An example relating serum biochemistry and haematology to alcohol consumption. The Journal of the Royal Statistical Society 1986; 35(3): Broughton PM, Holder R, Ashby D. Long-term trends in biochemical data obtained from two population surveys. Annals of Clinical Biochemistry 1986; 23(4): Cook DG, Shaper AG, Pocock SJ, Kussick SJ. Giving up smoking and the risk of heart attacks. A report from The British Regional Heart Study. Lancet 1986; 2(8520):

3 Cook DG, Shaper AG, Thelle DS, Whitehead TP. Serum uric acid, serum glucose and diabetes: relationships in a population study. Postgraduate Medical Journal 1986; 62(733): Cook DG. Can we detect an effect of unemployment on cardiovascular morbidity or mortality? Postgraduate Medical Journal 1986; 62(730): Phillips AN. Statistical issues in prospective studies of risk factors for ischaemic heart disease. Thesis: PhD University of London. Pocock SJ, Shaper AG, Phillips AN, Walker M, Whitehead TP. High density lipoprotein cholesterol is not a major risk factor for ischaemic heart disease in British men. British Medical Journal 1986; 292(6519): Shaper AG. Identification of risk factors for coronary heart disease. In Proceedings of the Glasgow heart disease symposium: Lipoproteins and coronary heart disease. Editors: Shepherd J, Packard CJ, Lorimer AR, Lawrie TDV, Morgan HG, Brownlie SM. Publishers: Blantyre Printing London & Glasgow 1986; Shaper AG, Pocock SJ, Phillips AN, Walker M. Identifying men at high risk of heart attacks: strategy for use in general practice. British Medical Journal 1986; 293(6545): Cook DG. Respiratory function, smoking and coronary heart disease in British men. Thesis: PhD University of London. Flegel KM, Shipley MJ, Rose G. Risk of stroke in non-rheumatic atrial fibrillation. Lancet 1987; 1(8532): (published erratum appears in Lancet 1987; 1(8537)::878). Johnston DW, Cook DG, Shaper AG. Type A behaviour and ischaemic heart disease in middle aged British men. British Medical Journal 1987; 295(6590): Macfarlane PW. British Regional Heart Study: the electrocardiogram and risk of myocardial infarction on follow-up. Journal of Electrocardiology 1987; 20 Suppl: Pocock SJ, Shaper AG, Cook DG, Phillips AN, Walker M. Social class differences in ischaemic heart disease in British men. Lancet 1987; 2(8552): Shaper AG, Phillips AN, Pocock SJ, Walker M. Systolic and diastolic blood pressures in the prediction of heart attacks and stroke. Journal of Hypertension 1987; 5(6):41. Shaper AG, Pocock SJ. Risk factors for ischaemic heart disease in British men [editorial]. British Heart Journal 1987; 57(1): Shaper AG, Phillips AN, Pocock SJ, Walker M. Alcohol and ischaemic heart disease in middle aged British men. British Medical Journal 1987; 294(6574): Shaper AG, Pocock SJ, Phillips AN, Walker M. A scoring system to identify men at high risk of a heart attack. Health Trends 1987; 19(2): Shaper AG. Risk factors for ischaemic heart disease. Health Trends 1987; 19:3-8. Walker M. Mortality and social class [letter]. Lancet 1987; 2(8561):746. Walker M, Shaper AG, Cook DG. Non-participation and mortality in a prospective study of cardiovascular disease. Journal of Epidemiology & Community Health 1987; 41(4): Whincup PH, Cook DG, Shaper AG. Alcohol consumption in England and Wales (letter). British Medical Journal 1987; 295(6608):

4 1988 Bruce NG, Shaper AG, Walker M, Wannamethee G. Observer bias in blood pressure studies. Journal of Hypertension 1988; 6(5): Cook DG, Shaper AG. Breathlessness, lung function and the risk of heart attack. European Heart Journal 1988; 9(11): Phillips AN, Shaper AG, Pocock SJ, Walker M, Macfarlane PW. The role of risk factors in heart attacks occurring in men with pre-existing ischaemic heart disease. British Heart Journal 1988; 60(5): Phillips AN, Shaper AG, Pocock SJ, Walker M. Parental death from heart disease and the risk of heart attack. European Heart Journal 1988; 9(3): Pocock SJ, Shaper AG, Ashby D, Delves HT, Clayton BE. The relationship between blood lead, blood pressure, stroke, and heart attacks in middle-aged British men. Environmental Health Perspectives 1988; 78: Pocock SJ, Delves HT, Ashby D, Shaper AG, Clayton BE. Blood cadmium concentrations in the general population of British middle-aged men. Human Toxicology 1988; 7(2): Pocock SJ, Shaper AG, Phillips AN, Walker M. Prediction of men at high risk of heart attack and its relevance to pilots. European Heart Journal 1988; 9 Suppl G: Shaper AG, Wannamethee G, Whincup P. Alcohol and blood pressure in middle-aged British men. Journal of Human Hypertension 1988; 2(2): Shaper AG, Ashby D, Pocock SJ. Blood pressure and hypertension in middle-aged British men. Journal of Hypertension 1988; 6(5): Shaper AG, Wannamethee G, Walker M. Alcohol and mortality in British men: explaining the U- shaped curve. Lancet 1988; 2(8623): Walker M, Shaper AG, Wannamethee G. Height and social class in middle-aged British men. Journal of Epidemiology & Community Health 1988; 42(3): Wannamethee G, Shaper AG. Changes in drinking habits in middle-aged British men. Journal of the Royal College of General Practitioners 1988; 38(315): Wannamethee G, Shaper AG. Men who do not drink: a report from the British Regional Heart Study. International Journal of Epidemiology 1988; 17(2): Weatherall R, Shaper AG. Overweight and obesity in middle-aged British men. European Journal of Clinical Nutrition 1988; 42(3): Whincup PH, Cook DG, Shaper AG. Social class and height [letter]. British Medical Journal 1988; 297(6654): Whincup PH, Cook DG, Shaper AG, Macfarlane DJ, Walker M. Blood pressure in British children: associations with adult blood pressure and cardiovascular mortality. Lancet 1988; 2(8616): Cook DG, Shaper AG. Breathlessness, angina pectoris and coronary artery disease. American Journal of Cardiology 1989; 63(13): Cook DG, Shaper AG, Macfarlane PW. Using the WHO (Rose) angina questionnaire in cardiovascular epidemiology. International Journal of Epidemiology 1989; 18(3): Elford J, Phillips AN, Thomson AG, Shaper AG. Migration and geographic variations in ischaemic heart disease in Great Britain. Lancet 1989; 1(8634):

5 Elford J, Shaper AG. Heart disease risks [letter]. Nature 1989; 340(6234):514. Elford J. Migration and ischaemic heart disease in the British Regional Heart Study. Thesis: PhD University of London. Phillips A, Shaper AG, Whincup PH. Association between serum albumin and mortality from cardiovascular disease, cancer, and other causes. Lancet 1989; 2(8677): (published erratum appears in Lancet 1990;335(8682):180). Phillips A, Shaper AG. Relative weight and major ischaemic heart disease events in hypertensive men. [Review]. Lancet 1989; 1(8645): Phillips AN, Shaper AG. Secondary prevention of coronary heart disease (letter). Lancet 1989; Phillips AN, Pocock SJ. Sample size requirements for prospective studies, with examples for coronary heart disease. Journal of Clinical Epidemiology 1989; 42(7): Pocock SJ, Ashby D, Shaper AG, Walker M, Broughton PM. Diurnal variations in serum biochemical and haematological measurements. Journal of Clinical Pathology 1989; 42(2): Pocock SJ, Shaper AG, Phillips AN. Concentrations of high density lipoprotein cholesterol, triglycerides, and total cholesterol in ischaemic heart disease. British Medical Journal 1989; 298(6679): Shaper AG, Phillips AN, Pocock SJ. Plasma cholesterol, coronary heart disease and cancer (letter). British Medical Journal 1989; 298:1381. Walker M, Shaper AG, Phillips AN, Cook DG. Short stature, lung function and risk of a heart attack. International Journal of Epidemiology 1989; 18(3): Wannamethee G, Shaper AG. Body weight and mortality in middle aged British men: impact of smoking. British Medical Journal 1989; 299(6714): Whincup PH, Cook DG, Shaper AG. Early influences on blood pressure: a study of children aged 5-7 years. British Medical Journal 1989; 299(6699): Whincup PH, Cook DG, Shaper AG. Blood pressure measurement in children: the importance of cuff bladder size. Journal of Hypertension 1989; 7(10): Bruce NG, Cook DG, Shaper AG, Thomson AG. Geographical variations in blood pressure in British men and women. Journal of Clinical Epidemiology 1990; 43(4): Bruce NG, Cook DG, Shaper AG. Differences between observers in blood pressure measurement with an automatic oscillometric recorder. Journal of Hypertension 1990; 8(4):S11-S13. Bruce NG, Cook DG, Shaper AG, Ratcliffe JG. Casual urine concentrations of sodium, potassium, and creatinine in population studies of blood pressure. Journal of Human Hypertension 1990; 4(6): Cook DG, Morris JK, Walker M, Shaper AG. Consultation rates among middle aged men in general practice over three years. British Medical Journal 1990; 301(6753): Cook DG, Shaper AG. Re: "Pulmonary function as a predictor of coronary heart disease" [letter]. American Journal of Epidemiology 1990; 132(3): Cook DG, Kussick SJ, Shaper AG. The respiratory benefits of stopping smoking. Journal of Smoking- Related Diseases 1990; 1(1):45-58.

6 Elford J, Phillips A, Thomson AG, Shaper AG. Migration and geographic variations in blood pressure in Britain. British Medical Journal 1990; 300(6720): Griffioen A. Alcohol and blood pressure: a cross sectional study of relationships in men and women. Thesis: MSc University of London. Perry IJ. Obesity, physical activity, alcohol intake and the prevalence of non-insulin dependent diabetes mellitus. Thesis: MSc University of London. Phillips AN, Thompson SG, Pocock SJ. Prognostic scores for detecting a high risk group: estimating the sensitivity when applied to new data. Statistics in Medicine 1990; 9(10): Shaper AG. Alcohol and mortality: a review of prospective studies. British Journal of Addiction 1990; 85(7): Walker M, Phillips A, Shaper AG. Blood cholesterol, social class and height [letter]. Journal of Public Health Medicine 1990; 12(2): Wannamethee G, Shaper AG. Weight change in middle-aged British men: implications for health. European Journal of Clinical Nutrition 1990; 44(2): Wannamethee G, Shaper AG. Weight change, perceived health status and mortality in middle-aged British men. Postgraduate Medical Journal 1990; 66(781): Whincup PH, Cook DG, Phillips AN, Shaper AG. ABO blood group and ischaemic heart disease in British men. British Medical Journal 1990; 300(6741): Bruce NG. An investigation of geographic blood pressure variations among men and women in Great Britain. Thesis: PhD University of London. Bruce N, Elford J, Wannamethee G, Shaper AG. The contribution of environmental temperature and humidity to geographic variations in blood pressure. Journal of Hypertension 1991; 9(9): Elford J, Whincup P, Shaper AG. Early life experience and adult cardiovascular disease: longitudinal and case-control studies. [Review]. International Journal of Epidemiology 1991; 20(4): Phillips AN, Smith GD. How independent are "independent" effects? Relative risk estimation when correlated exposures are measured imprecisely. Journal of Clinical Epidemiology 1991; 44(11): Phillips AN, Shaper AG. Serum calcium and blood pressure. Journal of Human Hypertension 1991; 5(6): Shaper AG, Wannamethee G, Walker M. Milk, butter, and heart disease [letter]. British Medical Journal 1991; 302(6779): Shaper AG, Wannamethee G, Walker M. Calf pain on walking, risk factors and cardiovascular outcome in middle-aged British men. In Epidemiology of Peripheral Vascular Disease. Editor: Fowkes F. G. R. Publishers: Springer Verlag, London 1991;(11) Shaper AG. Screening for men at high-risk of coronary heart disease. Journal of the Society of Occupational Medicine 1991;41(2): Shaper AG, Wannamethee G, Weatherall R. Physical activity and ischaemic heart disease in middleaged British men. British Heart Journal 1991; 66(5): (published erratum appears in Br Heart J 1992;67(2):209). Shaper AG, Elford J. Place of birth and adult cardiovascular disease: the British Regional Heart Study. Acta Paediatrica Scandinavica - Supplement 1991; 373:73-81.

7 Shaper AG, Phillips AN, Pocock SJ, Walker M, Macfarlane PW. Risk factors for stroke in middle aged British men. British Medical Journal 1991; 302(6785): Shaper AG, Walker M. Estimating the risk of heart attack (letter). British Medical Journal 1991; 303(6813): Tang JL. Giving up smoking and the risk of ischaemic heart disease. Thesis: PhD University of London. Wannamethee G, Shaper AG. Self-assessment of health status and mortality in middle-aged British men. International Journal of Epidemiology 1991; 20(1): Wannamethee G, Shaper AG. Alcohol intake and variations in blood pressure by day of examination. Journal of Human Hypertension 1991; 5(2): Whincup PH. A study of blood pressure in children in nine British towns. Thesis: PhD University of London Bruce NG, Cook DG, Shaper AG, Ratcliffe JG, Thomson AG. Casual urine concentrations of sodium and potassium and geographic blood pressure variations in Great Britain. Journal of Human Hypertension 1992; 6(2): Elford J, Shaper AG, Whincup P. Early life experience and cardiovascular disease--ecological studies. [Review]. Journal of Epidemiology & Community Health 1992; 46(1):1-8. Morris J. Loss of employment and ill health. Thesis: PhD University of London. Morris JK, Cook DG, Shaper AG. Non-employment and changes in smoking, drinking, and body weight. British Medical Journal 1992; 304(6826): Morris JK, Cook DG, Walker M, Shaper AG. Non-consulters and high consulters in general practice: cardio-respiratory health and risk factors. Journal of Public Health Medicine 1992; 14(2): Phillips AN, Neaton JD, Cook DG, Grimm RH, Shaper AG. Leukocyte count and risk of major coronary heart disease events. American Journal of Epidemiology 1992; 136(1): Phillips AN, Neaton JD, Cook DG, Grimm RH, Shaper AG. The leukocyte count and risk of lung cancer. Cancer 1992; 69(3): Shaper AG, Elford J. Regional variations in coronary heart disease in Great Britain: risk factors and changes in environment. In Coronary Heart Disease Epidemiology. From Aetiology to Public Health. Editors: Marmot M, Elliott P. Publishers: Oxford University Press Oxford 1992;(9): Shaper AG. Stroke [letter]. Lancet 1992;339 (8795):750. Tang JL, Cook DG, Shaper AG. Giving up smoking: How rapidly does the excess risk of ischaemic heart disease disappear? Journal of Smoking-Related Diseases 1992; 3(3): Wannamethee SG. Alcohol, cardiovascular disease and all cause mortality in British middle-aged men. Thesis: PhD University of London. Wannamethee G, Shaper AG. Physical activity and stroke in British middle aged men. British Medical Journal 1992; 304(6827): Wannamethee G, Shaper AG. Alcohol and sudden cardiac death. British Heart Journal 1992; 68(5): Wannamethee G, Shaper AG. Blood lipids: the relationship with alcohol intake, smoking, and body weight. Journal of Epidemiology & Community Health 1992; 46(3):

8 Whincup PH, Cook DG, Papacosta O, Walker M. Childhood blood pressure, body build, and birthweight: geographical associations with cardiovascular mortality. Journal of Epidemiology & Community Health 1992; 46(4): Whincup PH, Cook DG, Papacosta O. Do maternal and intrauterine factors influence blood pressure in childhood? Archives of Disease in Childhood 1992; 67(12): Whincup PH, Bruce NG, Cook DG, Shaper AG. The Dinamap 1846SX automated blood pressure recorder: comparison with the Hawksley random zero sphygmomanometer under field conditions. Journal of Epidemiology & Community Health 1992; 46(2): Bruce NG, Wannamethee G, Shaper AG. Lifestyle factors associated with geographic blood pressure variations among men and women in the UK. Journal of Human Hypertension 1993; 7(3): Cook DG, Whincup PH, Papacosta O, Strachan DP, Jarvis MJ, Bryant A. Relation of passive smoking as assessed by salivary cotinine concentration and questionnaire to spirometric indices in children. Thorax 1993; 48(1): Perry IJ, Wannamethee SG, Walker MK, Shaper AG. Sporting activity and hyperglycemia in middleaged men. Diabetes Care 1993; 16(4): Shaper AG, Wannamethee G, Macfarlane PW, Walker M. Heart rate, ischaemic heart disease, and sudden cardiac death in middle-aged British men. British Heart Journal 1993; 70(1): Shaper AG. Alcohol, the Heart, and Health [editorial]. American Journal of Public Health 1993; 83(6): Shaper AG. Alcohol and Coronary Heart Disease. Cardiovascular Risk Factors 1993; 3(4): Wannamethee G, Shaper AG, Macfarlane PW. Heart rate, physical activity, and mortality from cancer and other non-cardiovascular diseases. American Journal of Epidemiology 1993; 137(7): Whincup PH, Papacosta O, Cook DG. Initiation of hypertension in utero [letter]. British Medical Journal 1993; 306(6877):584. Whincup PH, Cook DG, Strachan DP, Papacosta O. Time trends in respiratory symptoms in childhood over a 24 year period. Archives of Disease in Childhood 1993; 68(6): Cook DG, Whincup PH, Jarvis MJ, Strachan DP, Papacosta O, Bryant A. Passive exposure to tobacco smoke in children aged 5-7 years: individual, family, and community factors. British Medical Journal 1994; 308(6925): Geroulakos G, O'Gorman D, Nicolaides A, Sheridan D, Elkeles R, Shaper AG. Carotid intima-media thickness: correlation with the British Regional Heart Study risk score. Journal of Internal Medicine 1994; 235(5): Morris JK, Cook DG, Shaper AG. Loss of employment and mortality. British Medical Journal 1994; 308(6937): Morris RW, Walker M, McCallum AK, Whincup PH, Ebrahim S. Access to cardiac catheterization. Access to surgery linked to social class (letter). British Medical Journal 1994; 308(6925):410. Perry IJ, Whincup PH, Shaper AG. Environmental factors in the development of essential hypertension. [Review]. British Medical Bulletin 1994; 50(2): Perry IJ, Wannamethee SG, Whincup PH, Shaper AG. Asymptomatic hyperglycaemia and major ischaemic heart disease events in Britain. Journal of Epidemiology & Community Health 1994; 48(6):

9 Shaper AG, Perry IJ. Screening people with diabetes for risk of coronary heart disease in general practice. Practical Diabetes 1994; 11: Shaper AG, Wannamethee G, Walker M. Physical activity, hypertension and risk of heart attack in men without evidence of ischaemic heart disease. Journal of Human Hypertension 1994; 8(1):3-10. Shaper AG, Wannamethee SG. Physical activity and cerebrovascular risk. In Neurocardiology Update: Proceedings of the III National Congress Italian Society of Cardiology. Editors: Nappi G, Richichi I, Michieli G, Friedman M. Publishers: Smith-Gordon London 1994;(2) Shaper AG, Wannamethee G, Walker M. Alcohol and coronary heart disease: a perspective from the British Regional Heart Study. International Journal of Epidemiology 1994; 23(3): Shaper AG. Water hardness and coronary heart disease. In Water and Public Health. Editors: Golding, AMB., Noah N, Stanwell-Smith R. Publishers: Smith-Gordon London 1994; Wannamethee G, Whincup PH, Shaper AG, Lever AF. Serum sodium concentration and risk of stroke in middle-aged males. Journal of Hypertension 1994; 12(8): Wannamethee G, Shaper AG. The association between heart rate and blood pressure, blood lipids and other cardiovascular risk factors. Journal of Cardiovascular Risk 1994; 1(3): Wannamethee G, Perry IJ, Shaper AG. Haematocrit, hypertension and risk of stroke. Journal of Internal Medicine 1994; 235(2): Wannamethee G, Shaper AG. Haematocrit: relationships with blood lipids, blood pressure and other cardiovascular risk factors. Thrombosis & Haemostasis 1994; 72(1): Wannamethee G, Shaper AG, Whincup PH. Ischaemic heart disease: association with haematocrit in the British Regional Heart Study. Journal of Epidemiology & Community Health 1994; 48(2): Whincup P, Cook D, Papacosta O, Walker M, Perry I. Maternal factors and development of cardiovascular risk: evidence from a study of blood pressure in children. Journal of Human Hypertension 1994; 8(5): Whincup PH, Perry IJ, Shaper AG. Regional differences in blood pressure in developed countries: Fetal influences. In Factors acting in early life. Editor: Swales JD. Publishers: Blackwell Scientific London, 1994; Chapter 2: Breimer LH, Wannamethee G, Ebrahim S, Shaper AG. Serum bilirubin and risk of ischemic heart disease in middle-aged British men. Clinical Chemistry 1995; 41(10): Coppola WG, Whincup PH, Papacosta O, Walker M, Ebrahim S. Scoring system to identify men at high risk of stroke: a strategy for general practice. British Journal of General Practice 1995; 45(393): Ebrahim S, Wannamethee G, McCallum A, Walker M, Shaper AG. Marital status, change in marital status, and mortality in middle-aged British men. American Journal of Epidemiology 1995; 142(8): Perry IJ, Wannamethee SG, Walker MK, Thomson AG, Whincup PH, Shaper AG. Prospective study of risk factors for development of non-insulin dependent diabetes in middle aged British men. British Medical Journal 1995; 310(6979): Perry IJ, Refsum H, Morris RW, Ebrahim SB, Ueland PM, Shaper AG. Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet 1995; 346(8987): Prospective Studies Collaboration. Cholesterol, diastolic blood pressure, and stroke: 13,000 strokes in 450,000 people in 45 prospective cohorts. Lancet 1995; 346( ):

10 Shaper AG. Alcohol and coronary heart disease. [Review]. European Heart Journal 1995; 16(12): Shaper AG. Alcohol and uricaemia [letter]. Alcohol & Alcoholism 1995; 30(2):263. Shaper AG. Mortality and alcohol consumption. Non-drinkers shouldn't be used as baseline [letter]. British Medical Journal 1995; 310(6975):325. Shaper AG. The "unhealthy abstainers" question is still important. Addiction 1995; 90(4): Walker M, Wannamethee G, Whincup PH, Shaper AG. Weight change and risk of heart attack in middle-aged British men. International Journal of Epidemiology 1995; 24(4): Wannamethee G, Shaper AG, Whincup PH, Walker M. Low serum total cholesterol concentrations and mortality in middle aged British men. British Medical Journal 1995; 311(7002): Wannamethee G, Shaper AG, Macfarlane PW, Walker M. Risk factors for sudden cardiac death in middle-aged British men. Circulation 1995; 91(6): Wannamethee G, Whincup PH, Shaper AG, Walker M, Macfarlane PW. Factors determining case fatality in myocardial infarction "who dies in a heart attack"? British Heart Journal 1995; 74(3): Wannamethee G, Ebrahim S, Shaper AG. Gamma-glutamyltransferase: determinants and association with mortality from ischemic heart disease and all causes. American Journal of Epidemiology 1995; 142(7): Wannamethee SG, Shaper AG, Ebrahim S. Respiratory function and risk of stroke. Stroke 1995; 26(11): Wannamethee SG, Shaper AG, Whincup PH, Walker M. Smoking cessation and the risk of stroke in middle-aged men. JAMA 1995; 274(2): Whincup P, Cook D, Papacosta O, Walker M. Birth weight and blood pressure: cross sectional and longitudinal relations in childhood. British Medical Journal 1995; 311(7008): Whincup PH, Wannamethee G, Macfarlane PW, Walker M, Shaper AG. Resting electrocardiogram and risk of coronary heart disease in middle-aged British men. Journal of Cardiovascular Risk 1995; 2(6): Griffin M. High resolution ultrasound increasing the predictive value of the British Regional Heart Study risk score. Thesis: MSc University of London. Morris RW, McCallum AK, Walker M, Whincup PH, Ebrahim S, Shaper AG. Cigarette smoking in British men and selection for coronary artery bypass surgery. Heart 1996; 75(6): Perry IJ. Risk factors for non-insulin dependent diabetes mellitus in middle-aged men. Thesis: PhD University of London. Perry IJ, Wannamethee SG, Whincup PH, Shaper AG, Walker MK, Alberti KG. Serum insulin and incident coronary heart disease in middle-aged British men. American Journal of Epidemiology 1996; 144(3): Phillips AN, Wannamethee SG, Walker M, Thomson A, Smith GD. Life expectancy in men who have never smoked and those who have smoked continuously: 15 year follow up of large cohort of middle aged British men. British Medical Journal 1996; 313(7062): Shaper AG. Obesity and cardiovascular disease. [Review]. Ciba Foundation Symposium ;

11 Shaper AG. Sensible but not particularly logical. (Commentary on Guidelines on sensible drinking). Addiction 1996; 91(1): Wannamethee G, Shaper AG. Blood pressure and cancer in middle-aged British men. International Journal of Epidemiology 1996; 25(1): Wannamethee SG, Perry IJ, Shaper AG. Hematocrit and risk of NIDDM. Diabetes 1996; 45(5): Wannamethee SG, Shaper AG. Patterns of alcohol intake and risk of stroke in middle-aged British men. Stroke 1996; 27(6): Wannamethee SG, Whincup PH, Shaper G, Walker M. Influence of fathers' social class on cardiovascular disease in middle-aged men. Lancet 1996; 348(9037): Wannamethee SG, Shaper AG, Ebrahim S. History of parental death from stroke or heart trouble and the risk of stroke in middle-aged men. Stroke 1996; 27(9): Whincup PH, Mendall MA, Perry IJ, Strachan DP, Walker M. Prospective relations between Helicobacter pylori infection, coronary heart disease, and stroke in middle aged men. Heart 1996; 75(6): Whincup PH, Cook DG, Adshead F, Taylor S, Papacosta O, Walker M et al. Cardiovascular risk factors in British children from towns with widely differing adult cardiovascular mortality. British Medical Journal 1996; 313(7049): Cook DG, Carey IM, Whincup PH, Papacosta O, Chirico S, Bruckdorfer KR et al. Effect of fresh fruit consumption on lung function and wheeze in children. Thorax 1997; 52(7): Leeson CP, Whincup PH, Cook DG, Donald AE, Papacosta O, Lucas A et al. Flow-mediated dilation in 9- to 11- year-old children: the influence of intrauterine and childhood factors. Circulation 1997; 96(7): McCallum AK, Whincup PH, Morris RW, Thomson A, Walker M, Ebrahim S. Aspirin use in middleaged men with cardiovascular disease: are opportunities being missed? British Journal of General Practice 1997; 47(420): Perry IJ, Wannamethee SG, Shaper AG. Serum insulin and risk of coronary heart disease. Nutrition Metabolism and Cardiovascular Diseases 1997; 7: Shaper AG, Wannamethee SG, Walker M. Body weight: implications for the prevention of coronary heart disease, stroke, and diabetes mellitus in a cohort study of middle aged men. British Medical Journal 1997; 314(7090): Taylor SJ, Whincup PH, Cook DG, Papacosta O. Blood pressure in pregnancy and fetal growth [letter]. Lancet 1997; 349(9054): Taylor SJ, Whincup PH, Cook DG, Papacosta O, Walker M. Size at birth and blood pressure: cross sectional study in 8-11 year old children. British Medical Journal 1997; 314(7079): Wannamethee SG, Shaper AG. Lifelong teetotallers, ex-drinkers and drinkers: mortality and the incidence of major coronary heart disease events in middle-aged British men. International Journal of Epidemiology 1997; 26(3): Wannamethee SG, Shaper AG, Whincup PH. Serum urate and the risk of major coronary heart disease events. Heart 1997; 78(2): Wannamethee SG, Shaper AG. Socioeconomic status within social class and mortality: a prospective study in middle-aged British men. International Journal of Epidemiology 1997; 26(3):

12 Wannamethee SG, Shaper AG, Perry IJ. Serum creatinine concentration and risk of cardiovascular disease: a possible marker for increased risk of stroke. Stroke 1997; 28(3): Wannamethee SG, Lever AF, Shaper AG, Whincup PH. Serum potassium, cigarette smoking, and mortality in middle-aged men. American Journal of Epidemiology 1997; 145(7): Whincup PH, Cook DG, Adshead F, Taylor SJ, Walker M, Papacosta O et al. Childhood size is more strongly related than size at birth to glucose and insulin levels in year-old children. Diabetologia 1997; 40(3): Lampe FC, Whincup PH, Wannamethee SG, Ebrahim S, Walker M, Shaper AG. Chest pain on questionnaire and prediction of major ischaemic heart disease events in men. European Heart Journal 1998; 19(1): Perry IJ, Wannamethee SG, Shaper AG. Prospective study of serum gammaglutamyltransferase and risk of NIDDM. Diabetes Care 1998; 21(5): Shaper AG, Wannamethee SG. The J-shaped curve and changes in drinking habit. [Review]. Novartis Foundation Symposium ; Taylor SJ, Hird K, Whincup P, Cook D. Relation between birth weight and blood pressure is independent of maternal blood pressure [letter]. British Medical Journal 1998; 317(7159):680. Walker MK, Whincup PH, Shaper AG, Lennon LT, Thomson AG. Validation of patient recall of doctordiagnosed heart attack and stroke: a postal questionnaire and record review comparison. American Journal of Epidemiology 1998; 148(4): Wannamethee SG, Shaper AG, Walker M, Ebrahim S. Lifestyle and 15-year survival free of heart attack, stroke, and diabetes in middle-aged British men. Archives of Internal Medicine 1998; 158(22): Wannamethee SG, Shaper AG, Durrington PN, Perry IJ. Hypertension, serum insulin, obesity and the metabolic syndrome. Journal of Human Hypertension 1998; 12(11): Wannamethee SG, Shaper AG, Whincup PH, Walker M. Adult height, stroke, and coronary heart disease. American Journal of Epidemiology 1998; 148(11): Wannamethee SG, Shaper AG. Alcohol, coronary heart disease and stroke: an examination of the J- shaped curve. [Review]. Neuroepidemiology 1998; 17(6): Wannamethee SG, Shaper AG, Walker M. Changes in physical activity, mortality, and incidence of coronary heart disease in older men. Lancet 1998; 351(9116): Whincup PH. Fetal origins of cardiovascular risk: evidence from studies in children. [Review]. Proceedings of the Nutrition Society 1998; 57(1): Cook DG, Whincup PH, Miller G, Carey IM, Adshead FJ, Papacosta O et al. Fibrinogen and factor VII levels are related to adiposity but not to fetal growth or social class in children aged years. American Journal of Epidemiology 1999; 150(7): Ebrahim S, Papacosta O, Whincup P, Wannamethee G, Walker M, Nicolaides AN et al. Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women: the British Regional Heart Study. Stroke 1999; 30(4): Lampe FC, Walker M, Lennon LT, Whincup PH, Ebrahim S. Validity of a self-reported history of doctor-diagnosed angina. Journal of Clinical Epidemiology 1999; 52(1): Perry IJ, Wannamethee SG, Shaper AG, Alberti KG. Serum true insulin concentration and the risk of clinical non-insulin dependent diabetes during long-term follow-up. International Journal of Epidemiology 1999; 28(4):

13 Perry IJ. Homocysteine and risk of stroke. Journal of Cardiovascular Risk 1999; 6(4): Shaper AG. Drinking after a heart attack (Editorial). Addiction 1999; 94(7): Walker M, Shaper AG, Wannamethee SG, Whincup PH. Measuring the prevalence of disease in middle-aged British men. Journal of the Royal College of Physicians of London 1999; 33(4): Wannamethee SG, Perry IJ, Shaper AG. Nonfasting serum glucose and insulin concentrations and the risk of stroke. Stroke 1999; 30(9): Wannamethee SG, Shaper AG. Weight change and duration of overweight and obesity in the incidence of type 2 diabetes. Diabetes Care 1999; 22(8): Wannamethee SG, Shaper AG. Physical activity and the prevention of stroke. Journal of Cardiovascular Risk 1999; 6(4): Wannamethee SG, Shaper AG. Type of alcoholic drink and risk of major coronary heart disease events and all-cause mortality. American Journal of Public Health 1999; 89(5): Wannamethee SG. Overview risk factors for stroke. Journal of Cardiovascular Risk 1999; 6(4): Wannamethee SG. Is serum uric acid a risk factor for coronary heart disease?. [Review]. Journal of Human Hypertension 1999; 13(3): Wannamethee SG, Shaper AG, Whincup PH, Walker M. Role of risk factors for major coronary heart disease events with increasing length of follow up. Heart 1999; 81(4): Whincup PH, Refsum H, Perry IJ, Morris R, Walker M, Lennon L et al. Serum total homocysteine and coronary heart disease: prospective study in middle aged men. Heart 1999; 82(4): Danesh J, Whincup P, Walker M, Lennon L, Thomson A, Appleby P et al. Chlamydia pneumoniae IgG titres and coronary heart disease: prospective study and meta-analysis. British Medical Journal 2000; 321(7255): Danesh J, Whincup P, Walker M, Lennon L, Thomson A, Appleby P et al. Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. British Medical Journal 2000; 321(7255): Danesh J, Whincup P, Walker M, Lennon L, Thomson A, Appleby P et al. High prevalence of potentially virulent strains of Helicobacter pylori in the general male British population. Gut 2000; 47(1): Ebrahim S, Wannamethee SG, Whincup P, Walker M, Shaper AG. Locomotor disability in a cohort of British men: the impact of lifestyle and disease. International Journal of Epidemiology 2000; 29(3): Lampe FC, Whincup PH, Wannamethee SG, Shaper AG, Walker M, Ebrahim S. The natural history of prevalent ischaemic heart disease in middle-aged men. European Heart Journal 2000; 21(13): Leng GC, Papacosta O, Whincup P, Wannamethee G, Walker M, Ebrahim S et al. Femoral atherosclerosis in an older British population: prevalence and risk factors. Atherosclerosis 2000; 152(1): Shaper AG, Wannamethee SG. Epidemiological confounders in the relationship between alcohol and cardiovascular disease. In Moderate alcohol consumption and cardiovascular disease. Editors: Paoletti R, Klatsky AL, Poli A, Zakhari S. Publishers: Kluwer Academic Publishers, Dordrecht

14 Shaper AG, Wannamethee SG. Alcohol intake and mortality in middle aged men with diagnosed coronary heart disease. Heart 2000; 83(4): Walker M, Shaper AG, Lennon L, Whincup PH. Twenty year follow-up of a cohort based in general practice in 24 British towns. Journal of Public Health Medicine 2000; 22(4): Wannamethee SG, Shaper AG, Alberti KGMM. Physical activity, metabolic factors, and the incidence of coronary heart disease and type 2 diabetes. Archives of Internal Medicine 2000; 160(14): Wannamethee SG, Shaper AG, Walker M. Physical activity and mortality in older men with diagnosed coronary heart disease. Circulation 2000; 102(12): Wannamethee SG, Shaper AG. HDL-cholesterol, total cholesterol and the risk of stroke in middleaged British men. Stroke 2000; 31(8): Wannamethee SG, Shaper AG, Whincup PH, Walker M. Characteristics of older men who lose weight intentionally or unintentionally. American Journal of Epidemiology 2000; 151(7): Whincup P, Danesh J, Walker M, Lennon L, Thomson A, Appleby P et al. Prospective study of potentially virulent strains of Helicobacter pylori and coronary heart disease in middle-aged men. Circulation 2000; 101(14): Danesh J, Whincup P, Walker M, Lennon L, Thomson A, Appleby P et al. Fibrin D-dimer and coronary heart disease: prospective study and meta-analysis. Circulation 2001; 103(19): Dekou V, Whincup P, Papacosta O, Ebrahim S, Lennon L, Ueland PM et al. The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British regional heart study. Atherosclerosis 2001; 154(3): Ebrahim S, Shlomo YB, Smith GD, Whincup P, Emberson J. Dementia and statins (letter). Lancet 2001; 357(9259):822. Lampe FC, Whincup PH, Shaper AG, Wannamethee SG, Walker M, Ebrahim S. Variability of angina symptoms and the risk of major ischemic heart disease events. American Journal of Epidemiology 2001; 153(12): Lampe FC, Walker M, Shaper AG, Brindle PM, Whincup PH, Ebrahim S. End points for predicting coronary risk must be clarified (letter). British Medical Journal 2001; 323(7309): Lampe FC, Morris RW, Whincup PH, Walker M, Ebrahim S, Shaper AG. Is the prevalence of coronary heart disease falling in British men? Heart 2001; 86(5): Malik I, Danesh J, Whincup P, Bhatia V, Papacosta O, Walker M et al. Soluble adhesion molecules and prediction of coronary heart disease: a prospective study and meta-analysis. Lancet 2001; 358(9286): Morris RW, Whincup PH, Lampe FC, Walker M, Wannamethee SG, Shaper AG. Geographic variation in incidence of coronary heart disease in Britain: the contribution of established risk factors. Heart 2001; 86(3): Vass A, Leng G, Papacosta O, Walker M, Lennon L, Whincup PH. Secondary prevention may help intermittent claudication (letter). British Medical Journal 2001; 322(7287):673. Walker M, Thomson A, Whincup PH. Screening for type 2 diabetes. Screening would have important resource implications for primary care (letter). British Medical Journal 2001; 323(7310): Wannamethee SG, Shaper AG. Physical activity in the prevention of cardiovascular disease: an epidemiological perspective. [Review]. Sports Medicine 2001; 31(2):

15 Wannamethee SG, Shaper AG, Perry IJ. Smoking as a modifiable risk factor for type 2 diabetes in middle-aged men. Diabetes Care 2001; 24(9): Wannamethee SG, Shaper AG, Walker M. Weight change, body weight and mortality: the impact of smoking and ill health. International Journal of Epidemiology 2001; 30(4): Wannamethee SG. Serum uric acid is not an independent risk factor for coronary heart disease. [Review]. Current Hypertension Rep 2001; 3(3): Wannamethee SG, Shaper AG, Walker M. Physical activity and risk of cancer in middle-aged men. British Journal of Cancer 2001; 85(9): Danesh J, Whincup P, Lewington S, Walker M, Lennon L, Thomson A et al. Chlamydia pneumoniae IgA titres and coronary heart disease; prospective study and meta-analysis. Eur Heart J 2002; 23(5): Emberson JR, Whincup PH, Walker M, Thomas M, Alberti KG. Biochemical measures in a populationbased study: effect of fasting duration and time of day. Annals of Clinical Biochemistry 2002;39(5): Lennon L.T. Can the world wide web be used to improve health knowledge management in the British Regional Heart Study? Thesis: MSc University of London. Thomas MC, Walker M, Lennon LT, Thomson AG, Lampe FC, Shaper AG. Non-attendance at reexamination 20 years after screening in the British Regional Heart Study. Journal of Public Health Medicine 2002;24: Wannamethee SG, Shaper AG. Physical activity and risk of coronary heart disease (review). Seminars in Vascular Medicine 2002;2(3): Wannamethee SG, Shaper AG. Taking up regular drinking in middle age: effect on major coronary heart disease events and mortality. Heart 2002;87(1): Wannamethee SG, Shaper AG. Wine and lifestyle: role in CVD and premature death. In Alcohol and Heart Disease. Edited bywatson RR, Myers AK. Published by Taylor & Francis London Chapter 3 p Wannamethee SG, Lowe GD, Whincup PH, Rumley A, Walker M, Lennon L. Physical activity and hemostatic and inflammatory variables in elderly men. Circulation 2002;105(15): Wannamethee SG, Shaper AG, Perry IJ, Alberti K-GMM. Alcohol consumption and the incidence of type II diabetes. J Epidemiol Community Health 2002;56(7): Wannamethee SG, Shaper AG, Whincup PH, Walker M. Migration within Great Britain and cardiovascular disease: early life and adult environmental factors. International Journal of Epidemiology 2002;31: Wannamethee SG, Shaper AG, Walker M. Weight Change, Weight Fluctuation, and Mortality. Archives of Internal Medicine. 2002;162: Whincup PH, Danesh J, Walker M, Lennon L, Thomson A, Appleby P et al. von Willebrand factor and coronary heart disease. Prospective study and meta-analysis. Eur.Heart J. 2002;23: Whincup PH, Emberson JR, Lennon L, Walker M, Papacosta O, Thomson A. Low prevalence of lipid lowering drug use in older men with established coronary heart disease. Heart 2002; 88(1): Homocysteine Studies Collaboration. (Whincup PH). Homocysteine and risk of ischaemic heart disease and stroke: 6000 events in 30 observational studies. JAMA 2002;288:

16 Prospective Studies Collaboration (BRHS: PH Whincup et al). Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002;360: Brindle P, Emberson JR, Lampe FC, Walker M, Whincup PH, Fahey T, Ebrahim SB. Coronary riskassessment: Framingham-based methods over-estimate risk in British middle-aged men. BMJ 2003; 327: Conroy RM, Pyorala K, Fitzgerald AP, Sans S, Menotti A, De Backer G et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. European Heart Journal 2003; 24(11): Danesh J, Whincup P, Walker M. Chlamydia pneumoniae IgA titres and coronary heart disease: prospective study and meta-analysis (letter). European Heart Journal 2003; 24(9):881. Emberson JR, Whincup PH, Morris RW, Walker M. Re-assessing the contribution of serum total cholesterol, blood pressure and cigarette smoking to the aetiology of coronary heart disease: impact of regression dilution bias. European Heart Journal 2003; 24(19): Lawlor DA,Emberson JR, Ebrahim SE, Whincup PH, Wannamethee SG, Walker M, Davey-Smith G. Is the association between parity and coronary heart disease due to biological effects of pregnancy or adverse lifestyle risk factors associated with childrearing? Findings from the British Women's Heart and Health Study and the British Regional Heart Study. Circulation 2003;107: Lawlor DA, Davey Smith G, Whincup P, Wannamethee G, Papacosta O, Dhanjil S, Griffin M, Nicolaides AN, Ebrahim S. Association between offspring birth weight and atherosclerosis in middle aged men and women: British Regional Heart Study. J Epidemiol Community Health Jun;57(6): Morris RW, Whincup PH, Emberson JR, Lampe FC, Walker M, Shaper AG. North-South Gradients in Britain for Stroke and CHD. Are They Explained by the Same Factors? Stroke 2003;34: Shaper A.G., Wannamethee S.G., Walker M. Pipe and cigar smoking and major cardiovascular events, cancer incidence and all-cause mortality in middle-aged British men. International Journal of Epidemiology 2003;32: Wannamethee SG, Shaper AG. Alcohol, bodyweight and weight gain in middle-aged men. Am. J Clin Nutr 2003;77: Wannamethee SG, Lowe GDO, Shaper AG, Whincup PH, Rumley A, Walker M, Lennon L. The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men. Thrombosis and Haemostasis 2003;90: Ebrahim S, Papacosta O, Wannamethee G, Adamson J. Social inequalities and disability in older men: prospective findings from the British Regional Heart Study. Social Science and Medicine. 2004;59: Emberson JR, Whincup PH, Morris RW, Walker M, Ebrahim S. Evaluating the impact of population and high risk strategies for the primary prevention of cardiovascular disease. Eur.Heart J. 2004;25(6): Emberson JR, Whincup PH, Morris RW, Walker M, Lowe GDO, Rumley A. Extent of regression dilution for established and novel coronary risk factors: results from the British Regional Heart Study. Eur J Cardio Prev Rehab 2004; 11: Emberson JR, Whincup PH, Morris RW, Walker M. Social class differences in coronary heart disease in middle-aged British men implications for prevention. Int J Epidemiol 2004; 33:

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