4. 心外膜リードもしくは心内膜リードの選択

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1 人工臓器 最近の進歩 Daiji TAKEUCHI 1. はじめに 1 2. 小児科領域の患者の特徴 3. 小児ペースメーカの適応 ( 表 1) American College of Cardiology ACC /American Heart Association AHA / Heart Rhythm Society HRS ) 1) 3) 7 10 著者連絡先 ptakeuci@hij.twmu.ac.jp 4. 心外膜リードもしくは心内膜リードの選択 1) 体格 20 kg 3) 5) 15 kg 2) 血栓症 6),7) 表 1 1) 3) 1. AVB wide QRS bpm 70 bpm QT

2 表 ) 9),10) 3) 静脈閉塞 ) 13) 13) Cohen ) 4) 閾値, リードトラブルや reintervention 表 2 15) 17) 7) 18),19) Medtronics Bipolar Capture Epi St. Jude Medical Myodex 4.1 F active-fixation lead SelectSecure Lead System Medtronic selective-site pacing SelectSecure Lead System 8 F Select Site model C304S-59 cm C304L-69 cm Medtronic 4.1 F Select Site model C304S-59 cm C304L-69 cm Medtronic SelectSecure Lead System 5. 体格とペースメーカ本体のサイズ 4 5 kg Solus 2526T St. Jude MedicalSolus mm 6 mm 5.9 cm g 8 11 cm g single chamber pacing 6. ペーシング様式 dual chamber pacing DDD dual chamber pacing DDD bpm bpm

3 DDD 2 1 single chamber VVI-VVIR dysshynchrony 20),21) 1 1),22) 24) 24),25) 26),27) 28),29) 30) 7. 植え込み部位 31),32) 8. デバイス感染 33),34) 1 8 5),35),36) 2010 AHA 37) 9. リード抜去の問題 Cecchin radiofrequency-powered sheath 94 8 major 4 minor 4 38) 10. 遠隔モニタリング Medtronic CareLink Biotronik Home monitoring St. Jude Medical Merlin 39) 41) 11. その他 1)MRI 検査対応のペーシングデバイス MRI 2011 FDA MRI Revo MRI SureScan Pacing System Medtronic MRI CT MRI 2) ワイヤレスペーシング 42),43) 12. まとめ

4 Jour nal of Ar tificial Organs Cardiac pacing in pediatric patients: a review 文献 1) Epstein AE, DiMarco JP, Ellenbogen KA, et al: ACC/AHA/ HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC/ AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiar rhythmia Devices) developed in collaboration with the American Association for Thoracic Surgery and Society of Thoracic Surgeons. J Am Coll Cardiol 51: e1-62, ) Silka MJ, Bar-Cohen Y: Pacemakers and implantable cardioverter-defibrillators in pediatric patients. Heart Rhythm 3: , ) McLeod KA: Cardiac pacing in infants and children. Heart 96: , ) Stojanov PL, Savic DV, Zivkovic MB, et al: Permanent endovenous pediatric pacing: absence of lead failure--20 years follow-up study. Pacing Clin Electrophysiol 31: , ) Kammeraad JAE, Rosenthal E, Bostock J, et al: Endocardial pacemaker implantation in infants weighing < or = 10 kilograms. Pacing Clin Electrophysiol 27: , ) Barakat K, Robinson NM, Spurrell RA: Transvenous pacing lead-induced thrombosis: a series of cases with a review of the literature. Cardiology 93: 142-8, ) Khairy P, Landzberg MJ, Gatzoulis MA, et al: Transvenous pacing leads and systemic thromboemboli in patients with intracardiac shunts: a multicenter study. Circulation 113: , ) Wierzbowska K, Krzemińska-Paku a M, Marszal-Marciniak M, et al: Symptomatic atrial pacemaker lead thrombosis: detection by echocardiography and successful surgical treatment. Pacing Clin Electrophysiol 24: 391-3, ) Silka MJ, Rice MJ: Paradoxic embolism due to altered hemodynamic sequencing following transvenous pacing. Pacing Clin Electrophysiol 14: , ) Johnson C, Galindez L: Multiple systemic emboli complicating the course of a patient with an atrial septal defect, an atrial septal aneurysm and an endocardial right atrial pacemaker lead. P R Health Sci J 17: 281-4, ) Figa FH, McCrindle BW, Bigras JL, et al: Risk factors for venous obstruction in children with transvenous pacing leads. Pacing Clin Electrophysiol 20: , ) Zuber M, Huber P, Fricker U, et al: Assessment of the subclavian vein in patients with transvenous pacemaker leads. Pacing Clin Electrophysiol 21: , ) Haghjoo M, Nikoo MH, Fazelifar AF, et al: Predictors of venous obstruction following pacemaker or implantable cardiover ter-defibrillator implantation: a contrast venographic study on 100 patients admitted for generator change, lead revision, or device upgrade. Europace 9: , ) Bar-Cohen Y, Berul CI, Alexander ME, et al: Age, size, and lead factors alone do not predict venous obstruction in children and young adults with transvenous lead systems. J Cardiovasc Electrophysiol 17: 754-9, ) McLeod CJ, Attenhofer Jost CH, War nes CA, et al: Epicardial versus endocardial permanent pacing in adults with congenital heart disease. J Interv Card Electrophysiol 28: , ) Cohen MI, Bush DM, Vetter VL, et al: Permanent epicardial pacing in pediatric patients: seventeen years of experience and 1200 outpatient visits. Circulation 103: , ) Bakhtiary F, Dzemali O, Bastanier CK, et al: Medium-term follow-up and modes of failure following epicardial pacemaker implantation in young children. Europace 9: 94-7, ) Papadopoulos N, Rouhollapour A, Kleine P, et al: Long-term follow-up after steroid-eluting epicardial pacemaker implantation in young children: a single centre experience. Europace 12: 540-3, ) Odim J, Suckow B, Saedi B, et al: Equivalent performance of epicardial versus endocardial permanent pacing in children: a single institution and manufacturer experience. Ann Thorac Surg 85: , ) Kim JJ, Friedman RA, Eidem BW, et al: Ventricular function and long-term pacing in children with congenital complete atrioventricular block. J Cardiovasc Electrophysiol 18: 373-7, ) Tantengco MV, Thomas RL, Karpawich PP: Left ventricular dysfunction after long-term right ventricular apical pacing in the young. J Am Coll Cardiol 37: , ) Kaltman JR, Ro PS, Zimmer man F, et al: Managed ventricular pacing in pediatric patients and patients with congenital heart disease. Am J Cardiol 102: 875-8, ) Thambo JB, Bordachar P, Garrigue S, et al: Detrimental ventricular remodeling in patients with congenital complete heart block and chronic right ventricular apical pacing. Circulation 110: , ) Chen CA, Wang JK, Lin MT, et al: Dilated cardiomyopathy after long-term right ventricular apical pacing in children with complete atrioventricular block: role of setting of ventricular pacing. J Card Fail 15: 681-8, ) Karpawich PP: Chronic right ventricular pacing and cardiac per formance: the pediatric perspective. Pacing Clin Electrophysiol 27: 844-9, ) Deshmukh P, Casavant DA, Romanyshyn M, et al: Permanent, direct His-bundle pacing: a novel approach to cardiac pacing in patients with normal His-Purkinje activation. Circulation 101: , ) Peschar M, de Swart H, Michels KJ, et al: Left ventricular septal and apex pacing for optimal pump function in canine hearts. J Am Coll Cardiol 41: , ) Vanagt WY, Prinzen FW, Delhaas T: Physiology of cardiac pacing in children: the importance of the ventricular pacing site. Pacing Clin Electrophysiol 31(Suppl 1): S24-7, ) Blanc JJ, Etienne Y, Gilard M, et al: Evaluation of different ventricular pacing sites in patients with severe heart failure: results of an acute hemodynamic study. Circulation 96: , ) M o a k J P, H a s b a n i K, R a m w e l l C, e t a l : D i l a t e d

5 cardiomyopathy following right ventricular pacing for AV block in young patients: resolution after upgrading to biventricular pacing systems. J Cardiovasc Electrophysiol 17: , ) Dodge-Khatami A, Kadner A, Dave H, et al: Left heart atrial and ventricular epicardial pacing through a left lateral thoracotomy in children: a safe approach with excellent functional and cosmetic results. Eur J Cardiothorac Surg 28: 541-5, ) Rausch CM, Hughes BH, Runciman M, et al: Axillary versus infraclavicular placement for endocardial heart rhythm devices in patients with pediatric and congenital heart disease. Am J Cardiol 106: , ) Silka MJ, Kron J, Dunnigan A, et al: Sudden cardiac death and the use of implantable cardioverter-defibrillators in pediatric patients. The Pediatric Electrophysiology Society. Circulation 87: 800-7, ) Klug D, Vaksmann G, Jar wé M, et al: Pacemaker lead infection in young patients. Pacing Clin Electrophysiol 26: , ) Silvetti MS, Drago F, Grutter G, et al: Twenty years of paediatric cardiac pacing: 515 pacemakers and 480 leads implanted in 292 patients. Europace 8: 530-6, ) Cohen MI, Bush DM, Gaynor JW, et al: Pediatric pacemaker infections: twenty years of experience. J Thorac Cardiovasc Surg 124: 821-7, ) Baddour LM, Epstein AE, Erickson CC, et al: Update on cardiovascular implantable electronic device infections and their management: a scientific statement from the American Heart Association. Circulation 121: , ) Cecchin F, Atallah J, Walsh EP, et al: Lead extraction in pediatric and congenital hear t disease patients. Circ Arrhythm Electrophysiol 3: , ) Jung W, Rillig A, Birkemeyer R, et al: Advances in remote monitoring of implantable pacemakers, cardiover ter defibrillators and cardiac resynchronization therapy systems. J Interv Card Electrophysiol 23: 73-85, ) Burri H, Senouf D. Remote monitoring and follow-up of pacemakers and implantable cardioverter defibrillators. Europace 11: 701-9, ) Hauck M, Bauer A, Voss F, et al: Home monitoring for early detection of implantable cardioverter-defibrillator failure: a single-center prospective observational study. Clin Res Cardiol 98: 19-24, ) Lee KL, Lau CP, Tse HF, et al: First human demonstration of cardiac stimulation with transcutaneous ultrasound energy deliver y: implications for wireless pacing with implantable devices. J Am Coll Cardiol 50: , ) Wieneke H, Konorza T, Erbel R, et al: Leadless pacing of the heart using induction technology: a feasibility study. Pacing Clin Electrophysiol 32: ,

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