HYPERACUTE STROKE CASE STUDIES. By Mady Roman Hyper Acute Stroke Nurse Practitioner RHH

Transcription

1 HYPERACUTE STROKE CASE STUDIES By Mady Roman Hyper Acute Stroke Nurse Practitioner RHH

2 MC Case study 82 years old, lady 9:30 well, in touch with her son 11:30 hairdresser came to her house and found her slumped in chair with left side weakness, unable to move, confused. GCS=14/15, NIHSS=16

3 MC Case study NIHSS on arrival= 16 confused partial gaze to right complete left hemianopia left minor facial paresis no movement to left arm no effort against gravity on left leg severe sensory loss on left side mild slurring of words complete neglect on left side

4 MC Case study Independent lady, living alone Recurrent chest infections, with no signs of infection on admission. Not known diabetic HTH, BP=155/71 mm/hg Patient nauseated on admission No contraindications for R-tpa

5 MC Case study CT scan

6 MC Case Study Would you thrombolyse?

7 MC Case study CT scan reported: There is low attenuation within the right basal ganglia, it is not possible to be certain whether this is an acute or area of infarction or long standing ischaemia. There is increased density to the right MCA. Ischaemia is also noted within the brainstem. No acute haemorrhage.

8 MC Case study Considered for thrombolysis. Consent received from family and patient. Proceeded to 3h40 from last seen well and 48 from arrival to hospital

9 MC Case Study Considered for thrombectomy

10 MC Case study CTA scan reported: clot in Right ICA The aortic arch is unfolded and there is significant tortuosity of the great vessels as they arise from the arch. There is no significant calcification or stenosis within the extracranial carotid arteries. There is occlusion of the right terminal carotid artery extending into the right M1. There is still reasonable opacification of the cortical branches of the right MCA, presumably as result of collateral flow. Both intracavernous internal carotid arteries are heavily calcified. There is poor flow and narrowing of the right internal carotid artery within the cavernous sinus.

11 MC Case Study Would you proceed to thrombectomy?

12 MC Case study Procedure too risky NOT for TROMBECTOMY Very tortuous Right CCA and Right ICA Proximal Right MCA Ischemic changes established in brain Previous history of myocardial infarction

13 MC Case study 14:35 Patient arrived in HASU from x-ray department; On arrival to HASU: GCS=15/15, NIHSS=13, confusion cleared, improving heminopia and left side weakness, improving speech. R-tpa infusion finished BP=201/100 mmhg, nausea still present. Bleed suspected by nursing staff

14 MC Case Study What would you do?

15 MC Case study Suspected bleed dismissed by medical staff on basis of improving neurology and long standing nausea. Labetalol given with success, BP=166/77 mghg

16 MC Case study 3:00 am next day nursing staff found patient vomiting, BP:201/100 mmhg 3:05 am patient become unresponsive, GCS dropped from 14/15 to 9/15 called and F1 doctor sent to review patient. NIHSS=23: patient not responding to voice, making incomprehensive sounds, withdrawing to pain on left side, pupils equal reacting to light. SNP ordered urgent CT head F1 requested SPR advice

17 MC Case study repeat CT: large bleed with midline shift. There is a new large acute haemorrhage in the right hemisphere centered around the right basal ganglia with extension to the lateral ventricles, 3rd and 4th ventricles. There is mass effect with mid line shift of 15 mm to the left. There is dilated left lateral ventricle in keeping with hydrocephalus. There is effacement of the cerebral sulci and the basal cisterns apart from cerebellomedullary cistern in keeping with an early cerebral herniation.

18 BP manged with IV Lobetalol and GTN patch. Antiemetic given with success Repeat bloods done Discussed with neurosurgeons not for intervention CXR desaturating, Sats target >94% MC case study

19 MC case study Blood results: HB=145 WCC=15.8 Plt=246 RCC=4.78 Ht=0.422 Neutrophilis=10.89 Lymphocytis=3.64 Monocytes=1.07 Prothrombin time=12.1 APTT=17.9 U&Es= normal values

20 MC Case Study What would you do?

21 MC study case Abnormal blood results recommendations For major bleeding (e.g. intracerebral) within 48 h of administration of R-tpa we recommend: All patients should be discussed with haematology team urgently Stop infusion of fibrinolytic drugs and other antithrombotic drugs. Administer FFP 12 ml/kg. Administer intravenous tranexamic acid 1 g tds. If there is depletion of fibrinogen, administer cryoprecipitate or fibrinogen concentrate. Further therapy should be guided by results of coagulation tests

22 MC study case Outcome Catastrophic bleed DNR agreed with family MC passes away at 16:00h same day. May RIP

23 KW Case Study 82 year old gentleman 11:50 am while having lunch with his wife developed sudden L side weakness and dropped his cutlery. GCS= 13/15 50 minutes later arrives in NAU via emergency ambulance.

24 KW Case Study NIHSS=21 severe L side weakness and inattention, complete heminopia partial facial palsy dysarthria BP=153/65 mm/hg, pulse=53, sat=94% BM=5.3, not known diabetic PMH: IHD, MI

25 KW Case Study 30 minutes later patient was having CT head which reported : possible hyperacute R MCA infarct On the 2.5mm axial slices the right middle cerebral artery does appear hyperdense in the distal part of the M1 segment. This could represent acute thrombus. There is possibly also subtle loss of grey white matter differentiation within the insular cortex on the right side. There is a very slight asymmetry between the sylvian fissures with the right insular cistern being smaller than on the left side. This could be due to subtle mass effect. Impression: There are some very subtle signs which could indicate an hyperacute right MCA territory infarct. There is no evidenceof haemorrhage.

26 KW Case Study Would you thrombolyse?

27 KW Case Study Consultant decided to thrombolyse. 2 hours after thrombolysis patient improving NIHSS=13. L limb weakness now mild More alert Improving dysarthria. BP=146/65 mm/hg Blood results normal

28 3h after thrombolysis nurses notice BP stars to rise but only reaches 185/78 mm/hg 4h after thrombolysis L side weakness becomes dense KW Case Study

29 KW Case Study What would you do?

30 KW Case Study The protocol for suspected intracranial bleed is followed: Bloods repeated Urgent CT scan ordered Close observation continues

31 KW Case Study urgent CT results show no haemorrhage and clear evidence of infarction Comparison is made with imaging performed earlier today(13.01 hours). There is now clear evidence of acute non haemorrhagic infarction of the head of the right caudate nucleus, putamen and the intervening anterior limb of the right internal capsule.

32 KW Case Study 24h after thrombolysis Patient s condition continues to deteriorate NIHSS: 16, with L limbs back to severe weakness Fluctuating GCS: 10-13/15 Patient agitated and failed dysphagia screen Repeat CT head done

33 KW Case Study Comparison is made with yesterday's CT scan. There is now haemorrhage into the thrombolised infarct. The haematoma is primarily centred upon the right putamen and there is surrounding oedema. There is moderate mass effect with early shift of the midline structures.

34 KW Case Study Not a candidate for surgical intervention due to his age and disability Next day patient becomes pyrexic and condition starts to deteriorate Blood cultures done and treatment started NG tube and CBD inserted Patient DNAR Transferred to ASU a few days later

35 Patients condition fluctuated a lot but he remains paraxial at all times 2 weeks later diagnosed with endocarditis 18 days later after thrombolysis patient died of complications. May he RIP KW Case Study outcome

36 Conclusions Working together can be the key to improving stroke services Applying CONSISTENCY in medical treatment following our protocols and recognising the role and experience of the SNP and HASU nurses would be beneficial. Developing a single practice through out region to approach strokes with all their complications in the acute phase, with good protocols in place can also help. This will require good communication and information sharing. Thank you for your attention and participation.