International CytoSorb Users Meeting. March 14 th Hotel Marivaux, Brussels

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1 3 rd International CytoSorb Users Meeting March 14 th Hotel Marivaux, Brussels

3 rd International CytoSorb Users Meeting Dear CytoSorb user, We are pleased to invite you to our 3rd International CytoSorb Users meeting on March 14 th 2016 in Brussels!

2 3 rd International CytoSorb Users Meeting Dear CytoSorb user, We are pleased to invite you to our 3rd International CytoSorb Users meeting on March 14 th 2016 in Brussels! Just one day before the start of the 36th ISICEM - as last year - we would like to update you on the latest scientific findings, first study results and case series from various indications. Again, the focus will be on giving you first-hand insights into clinical experiences with CytoSorb in various application fields. NEW For this 3 rd Users Meeting we prepared a novelty for you: individual bilateral meetings! Our objective is that you draw the most out of participating in this event, so meet those physicians for a short talk during the day that have already made specific experiences in applying the CytoSorb therapy or whom you wish to ask a certain question. You can book your meetings easily online and you will receive your individual schedule before the meeting. We are looking forward to meeting you in Brussels! Your CytoSorbents Europe Team

3 Program 12:00 am 1:00 pm 1:10 pm 1:30 pm Registration and lunch buffet Bilateral meetings Opening C Steiner, CytoSorbents Europe Introduction to the CytoSorb Therapy J Kellum, Pittsburgh, USA Clinical studies and experiences in sepsis Chair: A Grootendorst, Rotterdam, Netherlands & J Kellum, Pittsburgh, USA 1:30 pm Early cytokine adsorption in septic shock: The ACCES trial Z Molnar, Szeged, Hungary 1:45 pm Outcome observations in early vs late use in septic shock patients M Drüner, Emden, Germany 1:55 pm Treatment experience in various types of septic shock A Grootendorst, Rotterdam, Netherlands

4 2:05 pm In-vitro removal of inflammatory mediators, DAMPS and PAMPS M Gruda, CytoSorbents Corporation 2:20 pm 2:50 pm 3:20 pm Discussion and summary Coffee break Bilateral meetings Clinical studies and experiences in cardiac surgery Chair: X Monnet, Paris, France & Z Molnar, Szeged, Hungary 3:20 pm CytoSorb in cardiac surgery: background, rationale and first data AC Deppe, Cologne, Germany 3:35 pm Experiences with intraoperative CytoSorb treatment in cardiac surgery G Peeters, Angers, France 3:45 pm 4:10 pm Discussion and summary Clinical experiences from various fields of application Chair: D Tomescu, Bucharest, Romania & A Nierhaus, Hamburg, Germany 4:10 pm Quantification and kinetics of bilirubin removal with CytoSorb S Faenza, Bologna, Italy 4:20 pm Treatment experience with CytoSorb in severely burnt patients C Calin, Bucharest, Romania

4:30 pm Role of CytoSorb in the therapy of severe acute pancreatitis A Faltlhauser, Weiden,

B Kaya Ugur, Gaziantep, Turkey 4:50 pm Treatment support of rhabdomyolysis patients by CytoSorb

break Panel discussion and take home messages Moderator: Z Molnar Panelists: J Kellum, A

5 4:30 pm Role of CytoSorb in the therapy of severe acute pancreatitis A Faltlhauser, Weiden, Germany 4:40 pm Experience of CytoSorb in patients with septic shock: a retrospective analysis B Kaya Ugur, Gaziantep, Turkey 4:50 pm Treatment support of rhabdomyolysis patients by CytoSorb D Fries, Innsbruck, Austria 5:00 pm 5:30 pm 5:45 pm 6:15 pm Discussions and summary Coffee break Panel discussion and take home messages Moderator: Z Molnar Panelists: J Kellum, A Grootendorst, AC Deppe Closing remarks P Chan, CEO CytoSorbents Corporation Bilateral meetings 8:00 pm Dinner

NEW: One-on-one meetings You can book your bilateral meetings with other participants (physicians or CytoSorbents representatives) as soon as

Those short talks will take place during the breaks so that you won t miss any lecture.

Registration & information Please register online for your participation at the users meeting and your bilateral talks until March 1 st 2016 on

6 NEW: One-on-one meetings You can book your bilateral meetings with other participants (physicians or CytoSorbents representatives) as soon as your registration is done, but you can also be asked for bilateral talks by other participants. Those short talks will take place during the breaks so that you won t miss any lecture. A few days before the event you will receive your personal meeting schedule including the time and who you are going to meet. Registration & information Please register online for your participation at the users meeting and your bilateral talks until March 1 st 2016 on You are welcome to contact us for any further information: support@cytosorbents.com. CytoSorbents Europe GmbH Petra Hoffmann Bölschestraße 116, Berlin, Germany Tel: petra.hoffmann@cytosorbents.com

Venue Nearly 90 years ago, the Marivaux Hotel was one of the finest cinemas in Brussels. Today it is a tastefully renovated hotel in a contemporary style.

7 Venue Nearly 90 years ago, the Marivaux Hotel was one of the finest cinemas in Brussels. Today it is a tastefully renovated hotel in a contemporary style. With its location in the heart of Brussels, the Marivaux is situated within walking distance of the Grand Place and the Square - Brussels Meeting Center, where the 36 th ISICEM will take place. Hotel Marivaux Boulevard Adolphe Max Brussels / Belgium Tel: reception@hotelmarivaux.be

CytoSorbents Europe GmbH Bölschestraße 116 12587 Berlin Germany Tel + 49 30

8 CytoSorbents Europe GmbH Bölschestraße Berlin Germany Tel Fax support@cytosorbents.com

International. CytoSorb. Users Meeting. October 2 nd 2015 Pullman Hotel Schweizer Hof Berlin, Germany

International. CytoSorb. Users Meeting. October 2 nd 2015 Pullman Hotel Schweizer Hof Berlin, Germany 2 nd International CytoSorb Users Meeting October 2 nd 2015 Pullman Hotel Schweizer Hof Berlin, Germany 2nd International CytoSorb Users Meeting Dear CytoSorb user, Just before the start of the 28th Annual