NIAAA UPDATE. Daniel Falk, Ph.D. Brett Hagman, Ph.D. Robert Huebner, Ph.D. Division of Treatment and Recovery Research, NIAAA

Size: px

Start display at page:

Download "NIAAA UPDATE. Daniel Falk, Ph.D. Brett Hagman, Ph.D. Robert Huebner, Ph.D. Division of Treatment and Recovery Research, NIAAA"

Derick McBride
6 years ago
Views:

1 NIAAA UPDATE Daniel Falk, Ph.D. Brett Hagman, Ph.D. Robert Huebner, Ph.D. Division of Treatment and Recovery Research, NIAAA 11 th Annual RSA Satellite Session on Mechanisms of Behavior Change: San Antonio, Texas June 20, 2015

2 Topics Accomplishments DTRR MOBC portfolio update MOBC funding opportunities

3 Accomplishments Inclusion of MOBC in NIAAA Strategic Plan RFA R21 (2007) Established Mechanisms of Behavior Change Interdisciplinary Research Consortium (MIRC) Sponsored special issue of ACER Supported trans-nih initiatives Co-sponsored RSA Satellite Built and nurtured a research portfolio at NIAAA PAR R01, R21, R03 (2014)

(n=1), $305 K08 (n=1), $170 K24 (n=2), $357 R21 (n=2), $381 K05

4 Division of Treatment and Recovery Research MOBC Portfolio (Current) Total Costs (in thousands)= $18,871 (N=48) R01 (n=26), $13,854 T32 (n=1), $305 K08 (n=1), $170 K24 (n=2), $357 R21 (n=2), $381 K05 (n=2), $440 R42 (n=1), $511 U24 (n=1), $677 K23 (n=6), $926 R34 (n=6), $1,250

5 DTRR MOBC Portfolio (FY06-13) Applications Received Projects Funded Total Fiscal Year

6 Funding Opportunities.

7 FOA: MOBC PAR Title: Mechanisms of Behavior Change in the Treatment of Alcohol Use Disorders Three Possible Mechanisms: R01 (PAR ) R21 (PAR ) R03 (PAR ) Must Submit Letter of Intent Three Submission Dates March 17, 2016 We are working on renewing the PAR

8 MOBC PAR Rationale for PAR Provides a special review committee comprised of MOBC researchers Encourages INNOVATIVE & TRANS-DISCIPLINARY applications across multiple domains (e.g., neuroscience) R03 mechanism encourages junior investigators (e.g., post-docs) to submit and permits secondary data analyses Encourages applications that examine MOBC inside and outside the context of treatments (e.g., non-treatment seekers; self-change process) Encourages applications with a strong methodological focus (e.g., dynamic systems approach)

9 MOBC PAR SUBMISSION CHARACTERISTICS First two submissions and grants review have already occurred June 18 th, 2014 (First PAR Review) June 2 nd and 8th, 2015 (Second PAR Reviews) Applications 2014 Initial 2015 Revised Applications 2015 Total Funded R R R Total Overall success rate 7/19 = 37%

10 MOBC PAR Examples of Funded PAR Studies MOBC Funded Grants (N=7) Project Impact: In the Moment Project from Automatic Capture by Triggers fmri and Treatment Response with Binge Drinking Adolescents Perceived alcohol reward value and risk: Neural Correlates and Treatment Effects Psychological and Neural Mechanisms of Mindfulness and Cognitive Retraining Intervention Ingredients and Mechanisms of an Efficacious Motivational Interview Meta-Regression to Identify the SBIRT structure and Content on Outcome Shifts in Behavioral Allocation Patterns as an Alcohol Recovery Mechanism

11 Other Program Announcements Alcohol Use Disorders: Treatment, Services, and Recovery Research R01: PA R21: PA R03: PA Research Domain #2: Behavioral Therapies and Mechanisms of Behavioral Change Conduct longitudinal studies of the natural history of behavioral change in drinking behavior. Transdisciplinary research including genetic, electrophysiological, and imaging techniques is encouraged. Innovative measures of real-time cognitive and affective change also should be developed. Reanalyze existing studies (secondary analyses) with new models looking at potential mechanisms of change prior to treatment, and within, outside, and after treatment. Conduct experiments to elucidate the causal relationship between proposed mechanisms of behavioral change and treatment outcomes. This program announcement is being updated

12 NIH Initiative Basic Behavior and Social Science Opportunity Network (OppNet) Trans-NIH initiative, established Nov. 2009, involving 24 NIH institutes and 5 Centers Goal: Increase NIH funding of basic behavioral and social sciences research (b-bssr). Mechanisms and processes that influence behavior at the individual, group, community and population level. Basic mechanisms funded ($71.6 million; N= 167 grants;): self-regulation, behavioral maintenance, decision making, stress, stigma, sleep, social environment, culture, resilience Plans underway to continue OppNet (FY 15-20)

13 NIH Initiative Science of Behavior Change (SOBC) Goal: Identify common mechanisms that drive initiation and maintenance of behavior change across disorders Encouraged multi-disciplinary approaches: social psychology, behavioral economics, and cognitive and affective neuroscience RFA - 10 R01s (2010); 7 admin supplements (2013) SOBC re-approved for next 5 years: 4 RFAs (in review): self regulation, stress, interpersonal/social processes Identify the most promising intervention targets Develop appropriate measures and approaches to engage targets Validate putative targets against disease outcomes

14 Recap NIAAA remains committed to MOBC research Take advantage of the PAR and other FOAs keep those applications coming! Focus on INNOVATION & IMPACT Funding support available from both NIAAA and NIH

15 Thank You For more information, please contact: Daniel Falk, Ph.D. NIAAA Brett Hagman, Ph.D. NIAAA

MOBC NIAAA UPDATE Brett Hagman, Ph.D. Robert Huebner, Ph.D. Division of Treatment and Recovery Research, NIAAA

MOBC NIAAA UPDATE Brett Hagman, Ph.D. Robert Huebner, Ph.D. Division of Treatment and Recovery Research, NIAAA 12 th Annual RSA Satellite Session on Mechanisms of Behavior Change: New Orleans, Louisiana