European Academy of Andrology Centre Report Name and address of Centre

Transcription

1 Name and address of Centre Department of Andrology and Reproductive Endocrinology Medical University of Łódż (Lodz) Łódż, 5 Sterling str. Poland Type of Centre University University Hospital Private Centre Other (please specify) X 1. Director Prof. dr. hab. Med. Krzysztof Kula 2. Director (if more Institutions in the Centre) Dept. of Reproductive Endocrinology, Director Prof. dr hab. Med. Jolanta Slowikowska-Hilczer 3. Present Staff (Senior Scientists) 1) Name Prof dr hab med. Krzysztof Kula, M.D., Ph.D. Degree Professor and chairmen Speciality Internal medicine, andrology Academician X Affiliated Member Clinical Andrologist X 2) Name Prof dr hab med. Jolanta Slowikowska-Hilczer M.D., Ph. D. Degree professor Speciality Pediatrics, endocrinology, andrology Academician X Affiliated Member Clinical Andrologist X 3) Name Dr hab med Renata Walczak- Jedrzejowska Degree adjunct, scientist, in charge of laboratory and teaching program Speciality molecular biology Academician Affiliated Member Clinical Andrologist Insert any additional staff below (if required) MD/Biologists/Chemists Name 1) Degree Dr n Med Katarzyna Marchlewska Adjunct, scientist, in charge of 1

2 contracts Speciality biochemistry Full time/part time Part time Academician Affiliated Member Clinical Andrologist 2) Name Dr n mad Eliza Filipiak Degree assistant Speciality biotechnology Full time/part time Part time Academician Affiliated Member Clinical Andrologist 3) Name Dr n med. Elżbieta Oszukowska Degree Hospital assistant Speciality Urology Full time/part time Part time Academician X Affiliated Member Clinical Andrologist X 4) Name Degree Speciality Full time/part time Academician Affiliated Member Clinical Andrologist Insert any additional staff below (if required) PhD Students Nurses 1) Name Dr Katarzyna Bajszczak 2) Name Dr Anna Świerczynska-Cieplucha 3) Name 1) Name Elżbieta Gajda 2) Name 3) Name Laboratory Technicians 1) Name Teresa Porada, full time 2) Name Boguslawa Cyniak part tima 3) Name Administrative Personnel 1) Name Anna Gościmska 2) Name 3) Name Insert any additional staff below (if required) Anna Olejniczak - supportive personnel 2

3 For each staff category please specify changes (increased or decreased since last EAA site visit Physicians Unchanged Increased Decreased X Nurses Unchanged X Increased Decreased Laboratory Technicians Unchanged Increased Decreased X 3 Administrative Personnel Unchanged X Increased Decreased Overall comment is personnel staff enough for centres activities? Yes No X Further comment 4. Clinical Activity A. Outpatients: Consultations per year in the last 3 years New patients Controls Type of patients in the last years (%) Infertility Erectile dysfunction Hypogonadotropic Hypogonadism Klinefelter Gynaecomastia Varicocele Cryptorchidism Male sex accessory gland infections Testicular tumours Disorders of gender identity Other B. Ultrasound (testis, penile, prostate) total Controls

4 C. Andrological surgery procedures Testicular biopsies Varicocele ligation Prostate biopsies BPH Prostate cancer Vasectomy Vaso-vasostomy Other 5. A. Andrology laboratory activity Semen analyses Sperm antibodies Seminal markers B. Andrology laboratory activity Sperm banking donors Yes No X Sperm banking cancer patients Yes No X If yes: Number of samples C. Hystopathologial evaluation of biopsies Yes X No 5. D. Reproductive Hormones Assays Yes X No If yes please specify type of assays and number of samples in the last year 5. E. Y chromosome microdeletions according to EAA/EMQN guidelines If yes number of tests in the past year Yes No X 11 Participation to the EAA quality control scheme? Yes X No If no, specify if available in another lab of the same hospital Yes No Blood karyotyping Yes X No If no, specify if available in another lab of the same hospital Yes No Other genetic tests (please specify) 4

5 6. Collaborations with other Clinical Units of the University/Hospital IVF Unit Yes X No If yes please specify: Children, Endocrinology, IVF, Urology, Genetics, Pathology Urology Clinic Yes X No Endocrine Clinic Yes X No Genetics Lab/Unit Yes X No Paediatric Unit Yes X No Central Hospital Laboratory Yes X No Private Centres Yes X No If yes please specify: 7. Clinical teaching activity Duration of training (years): 2 Number A: Trainees in the last five years 6 B: Trainees who passed EAA-ESAU\exam for Clinical Andrologist in the last 5yrs 8 C: Trainees working in the centre preparing to pass the EAA-ESAU examination 6 D: Ph D Students 180 E: Medical Students 560 F: Other students 8. Formal Andrology teaching program Yes No X If yes: specify duration (years/months): Years Months Hours of formal teaching per year Professional training (weeks/months) Medical Students 41 h per 1 student 0 Ph D Students 60 h per 1 student 9 months Post Graduate students 4 years per 1 student Trainees Other degrees (please specify) 9. Research Activity Please list the main papers in peer review journals in the last 3 years with I.F. in a separate file. 10. Research Funding the amount of available funds in the last 3 years and their source (Government, European Union, University, Local Government, Pharmaceutical Industries, Banks, Foundations.) 5

6 Year 2013 Total amount ( ) ( ) Funding Source(s) National Center of Sciences (Poland) Year 2014 Total amount ( ) ( ) Funding Source(s) National Center of Sciences (Poland) Year 2015 Total amount ( ) ( ) Funding Source(s) National Center of Sciences (Poland) Insert any additional funding below if required 11. Please report the main improvements of the Centre following the (last) EAA site visit Clinical Activity - stable Laboratory Activity - an increase: by introducing DNA fragmentation tests Research Activity - an increase Teaching - an increase 12. Overall considerations by the Centre Director A. The centre is growing Is stable X Has problems For our authorities the minimum number of teaching hours per If has problems, please specify academic teacher is unrealistically high. This can not be replaced by research of Ph. Ds. or scientific achievements (publications). Hence a number of academic teachers is minimal. B. Other Comments by the Centre Director 6

7 13. Anticipated future changes in the Centre The present Polish Health Ministry decided to substantially support the development of andrology and reproductive medicine in Poland. Due to this we expect to be selected as the Andrology Center in Poland. We expect also financial dotation from the Health Ministry. Date: June 11, 2016 Director s signature Prof dr hab med. Krzysztof Kula Publications Original Papers 1. Walczak-Jędrzejowska R, Słowikowska-Hilczer J, Oszukowska E, Marchlewska K, Filipiak E, Kula K. Oestradiol and testosterone inhibit rat seminiferous tubule development in hormone-specific ways. Reprod Biol, (3): Marchlewska K, Kula K, Walczak-Jędrzejowska R, Kula W, Oszukowska E, Filipiak E, Moszura T, Slowikowska-Hilczer J. Maturational changes in connexin 43 expression in the seminiferous tubules may depend on thyroid hormone action. Arch Med Sci Feb 21;9(1):139-45, 3. Filipiak E, Suliborska D, Laszczynska M, Walczak-Jędrzejowska R, Oszukowska E, Marchlewska K, Kula K, Slowikowska-Hilczer J. Estrogen receptor alpha localization in the testes of men with normal spermatogenesis. Folia Histochem Cytobiol. 2012; 50(3): , 4. Walczak-Jędrzejowska R, Marchlewska K, Oszukowska E, Filipiak E, Bergier L, Slowikowska- Hilczer J. Semen analysis standardization. Is there any problem in Polish laboratories? Asian J Androl 2013;15(5):616-21, 5. Bajszczak K, Szarras-Czapnik M, Oszukowska E, Marchlewska K, Walczak-Jędrzejowska R, Filipiak E., Dobrowolski D., Różański W., Kula K., Słowikowska-Hilczer J. Kliniczne i psychologiczne konsekwencje odroczenia operacji obojnaczych zewnętrznych narządów płciowych do okresu dojrzałości u pacjentki z częściową niewrażliwością na androgeny. Endokrynol Ped, 2013; 2, 69-80, 6. Szyska-Skrobot D, Marchlewska K, Walczak-Jędrzejowska R, Oszukowska E, Filipiak E, Kula P, Mężyk R, Kowalska A, Jaszewski R, Słowikowska-Hilczer J, Kula K. Free and bioavailable fractions of sex steroids may influence bones in young men, depending on age and oestradiol level. Pol Endocrinol 2014; 65(5):357-64, 7. Jastrzębska, S, Walczak-Jędrzejowska R, Kramek E, Marchlewska K, Oszukowska E, Filipiak E, Kula K, Slowikowska-Hilczer J. Relationship between sexual function, body mass index and levels of sex steroid hormones in young men. Pol Endocrinol, 2014; 65(3): , 8. Filipiak E, Marchlewska K, Oszukowska E, Walczak-Jędrzejowska R, Świerczynska-Cieplucha A, Kula K, Slowikowska-Hilczer J. Presence of aerobic micro-organisms and their influence on basic semen parameters in infertile men. Andrologia. 2014, doi: /and.12338, 7

8 9. Andraszek K, Banaszewska D, Szostek M, Wójcik E, Czubaszek M, Walczak-Jędrzejowska R. Use of silver nitrate for the assessment of sperm measurements in selected farm and free-living animal species. Bull Vet Inst Pulawy 2014, 58: , 10. Banaszewska D, Andraszek K, Szostek M, Wójcik E, Danilewicz A, Walczak-Jędrzejowska R. Analysis of stallion semiologic semen parameters. Med. Weter 2015, 71(9): Banaszewska D, Czubaszek M, Walczak-Jędrzejowska R, Andraszek K. Morphometric dimensions of the stalli on sperm head depending on the staining metod. Bull Vet Inst Pulawy 2015, 59: , 12. Marchlewska K, Slowikowska-Hilczer J, Walczak-Jędrzejowska R, Oszukowska E, Filipiak E, Kula K. The long-term effects of FSH and triiodothyronine administartion during the pubertal period on connexin 43 expression and spermatogenesis efficiency in adult rats. J Exp Zool A Ecol Genet Physiol 2015, 323(4):256-65, 13. Slowikowska-Hilczer J, Szarras-Czapnik M, Wolski JK, Oszukowska E, Hilczer M, Jakubowski L, Walczak-Jedrzejowska R, Marchlewska K, Filipiak E, Kaluzewski B, Baka-Ostrowska M, Niedzielski J, Kula K. The risk of neoplasm associated with dysgenetic testes in prepubertal and pubertal/adult patients. Folia Histochem Cytobiol. 2015;53(3): Lee DM, Tajar A, Ravindrarajah R, Pye SR, O'Connor DB, Corona G, O'Connell M, Gielen E, Boonen S, Vanderschueren D, Pendleton N, Finn JD, Bartfai G, Casanueva FF, Forti G, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean ME, Punab M, Wu FC, O'Neill TW; the European Male Aging Study Group (Łódź: Słowikowska-Hilczer J, Walczak-Jędrzejowska R). Frailty and Sexual Health in Older European Men. J Gerontol A Biol Sci Med Sci Jul;68(7):837-44, 15. Camacho, E. M., Huhtaniemi, I. T., O'Neill, T. W., Finn, J. D., Pye, S. R., Lee, D. M., Tajar, A., Bartfai, G., Boonen, S., Casanueva, F. F., Forti, G., Giwercman, A., Han, T. S., Kula, K., Keevil, B., Lean, M. E., Pendleton, N., Punab, M., Vanderschueren, D., and Wu, F. C. (Łódź : Słowikowska- Hilczer J, Walczak-Jędrzejowska R.) Age-associated changes in hypothalamic-pituitary-testicular function in middle-aged and older men are modified by weight change and lifestyle factors: longitudinal results from the European Male Ageing Study. Eur J Endocrinol 2013, 168, , 16. Ohlsson, C., Nilsson, M. E., Tivesten, A., Ryberg, H., Mellstrom, D., Karlsson, M. K., Ljunggren, O., Labrie, F., Orwoll, E. S., Lee, D. M., Pye, S. R., O'Neill, T. W., Finn, J. D., Adams, J. E., Ward, K. A., Boonen, S., Bartfai, G., Casanueva, F. F., Forti, G., Giwercman, A., Han, T. S., Huhtaniemi, I. T., Kula, K., Lean, M. E., Pendleton, N., Punab, M., Vanderschueren, D., Wu, F. C., and Vandenput, L. and EMAS study Group (Łódź, Słowikowska-Hilczer J, Walczak-Jędrzejowska R.): Comparisons of immunoassay and mass spectrometry measurements of serum estradiol levels and their influence on clinical association studies in men. J Clin Endocrinol Metab 2013, 98(6), E , 17. Vanderschueren D, Pye SR, O'Neill TW, Lee DM, Jans I, Billen J, Gielen E, Laurent M, Claessens F, Adams JE, Ward KA, Bartfai G, Casanueva FF, Finn JD, Forti G, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean ME, Pendleton N, Punab M, Wu FC, Boonen S; EMAS Study Group (Łódź: Słowikowska-Hilczer J, Walczak-Jędrzejowska R). Active vitamin D (1,25-dihydroxyvitamin D) and bone health in middle-aged and elderly men: the European Male Aging Study (EMAS). J Clin Endocrinol Metab Mar;98(3): , 18. Ravindrarajah R, Lee DM, Pye SR, Gielen E, Boonen S, Vanderschueren D, Pendleton N, Finn JD, Tajar A, O'Connell MD, Rockwood K, Bartfai G, Casanueva FF, Forti G, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean ME, Punab M, Wu FC, O'Neill TW; European Male Aging Study Group (Łódź: Słowikowska-Hilczer J, Walczak-Jędrzejowska R). The ability of three different models 8

9 of frailty to predict all-cause mortality: results from the European Male Aging Study (EMAS). Arch Gerontol Geriatr Nov-Dec;57(3): , 19. Lee DM, Vanderschueren D, Boonen S, O'Neill TW, Pendleton N, Pye SR, Ravindrarajah R, Gielen E, Claessens F, Bartfai G, Casanueva FF, Finn JD, Forti G, Giwercman A, Han TS, Huhtaniemi IT, Kula K, Lean ME, Punab M, Wu FC; the European Male Ageing Study Group (Łódź: Słowikowska- Hilczer J, Walczak-Jędrzejowska R). Association of 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D and parathyroid hormone with mortality among middle-aged and older European men. Age Ageing. 2014, 43(4): , 20. Corona G1, Wu FC, Rastrelli G, Lee DM, Forti G, O'Connor DB, O'Neill TW, Pendleton N, Bartfai G, Boonen S, Casanueva FF, Finn JD, Huhtaniemi IT, Kula K, Punab M, Vanderschueren D, Rutter MK, Maggi M; EMAS Study Group. (Łódź: Słowikowska-Hilczer J, Walczak-Jędrzejowska R). Low prolactin is associated with sexual dysfunction and psychological or metabolic disturbances in middle-aged and elderly men: the European Male Aging Study (EMAS). J Sex Med Jan;11(1):240-53, 21. Pye SR, Huhtaniemi IT, Finn JD, Lee DM, O'Neill TW, Tajar A, Bartfai G, Boonen S, Casanueva FF, Forti G, Giwercman A, Han TS, Kula K, Lean ME, Pendleton N, Punab M, Rutter MK, Vanderschueren D, Wu FC; EMAS Study Group. (Łódź: Słowikowska-Hilczer J, Walczak- Jędrzejowska R). Late-onset hypogonadism and mortality in aging men. J Clin Endocrinol Metab Apr;99(4): , Review articles 1. Słowikowska-Hilczer, J., Szarras-Czapnik, M., Marchlewska, K., Filipiak, E., Oszukowska, E., Walczak-Jędrzejowska, R., Kula, K. Zespół dysgenetycznych jąder: patogeneza i konsekwencje kliniczne. Ped Endocrinol 2013; 1, 67-76, 2. Walczak-Jędrzejowska R, Bakalczuk Sz, Berger A, Bergier L, Filipiak E, Frącki S, Jędrzejczak P, Kula K, Marchlewska K, Piasecka M, Puacz E, Słowikowska-Hilczer J,Taszarek-Hauke G, Zagocka E. Rekomendacje. Podstawowe Badanie nasienia. Diagnosta Laboratoryjny, Rok XIII, 1(37), styczeń 2015, 8-16, Books 1. Marchlewska K., Słowikowska-Hilczer J., Walczak-Jędrzejowska R., Oszukowska E., Filipiak E., Kula K. 2013, Hormony gruczołu tarczowego a czynność jądra. w: Układ płciowy męski, Badania kliniczne i doświadczalne. Wydawnictwo Pomorskiego Uniwersytetu Medycznego w Szczecinie, Filipiak E., Marchlewska K., Słowikowska-Hilczer J., Walczak-Jędrzejowska R., Oszukowska E., Bergier L., Kula K. 2013, Badanie ogólne nasienia jako element diagnostyki laboratoryjnej męskiej płodności, w: Układ płciowy męski, Badania kliniczne i doświadczalne. Wydawnictwo Pomorskiego Uniwersytetu Medycznego w Szczecinie, Słowikowska-Hilczer J., Szarras-Czapnik M., Walczak-Jędrzejowska R., Marchlewska K., Oszukowska E., Filipiak E., Kula K. 2013, Różnicowanie i rozwój męskiej gonady, w: Układ 9

10 płciowy męski, Badania kliniczne i doświadczalne. Wydawnictwo Pomorskiego Uniwersytetu Medycznego w Szczecinie, Walczak-Jędrzejowska R i Kula K. Rola steroidowych hormonów jądra i ich interakcji przy wywołaniu dojrzewania kanalików plemnikotwórczych, w: Układ płciowy męski, Badania kliniczne i doświadczalne. Pod redakcją M. Piaseckiej. Wydawnictwo Pomorskiego Uniwersytetu Medycznego w Szczecinie. 2013;