Programme Programme GUIDE Course Good Research Practices: GCP and GLP
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1 Programme Programme GUIDE Course Good Research Practices: GCP and GLP Monday March 20, 2017 Subject New Drug Development; Good Research Practices: Good Clinical Practices: Introduction Organization GUIDE Graduate School for Drug Exploration University of Groningen Responsible teacher Prof. JanHasker G. Jonkman, Ph.D., F.C.P., F.R.Q.A., R.Ph. Professor em. Quality Management in Drug Research and Manufacturing University of Groningen PharmAdvices P.O. Box 10 NL-7920 AA ZUIDWOLDE The Netherlands Phone : Mobile : Fax: research@jhgjonkman.nl Web: Medische Wetenschappen, Farmacie, Tandheelkunde en 09:00-10:00 Welcome Introduction of the participants Introduction on the Course 10:00-10:15 Introduction on New Drug Development (Part I) 10:15-10:30 Break 10:30-11:45 Introduction on New Drug Development (Part II) 11:45-12:30 Marketing Authorization Procedures (L. Vromans, MA)
2 12:30-13:15 Lunch 13:15-14:00 Good Research Practices: GCP (Part I) 14:00-15:00 Good Research Practices: GCP (Part II) 15:00-15:15 Break 15:15-15:45 Video - Big pharma and 21st Century drug development (Prof. Dr. Chas Bountra) 15:45 16:00 Introduction on the Case Studies 16:00 - end Preparation of Case Studies (Home work)
3 Tuesday March 21, 2017 Subject Good Clinical Practices: Theory 09:00-10:15 Good Clinical Practices: the European Directives (Part I) 10:15-10:30 Break 10:30-11:00 Good Clinical Practices: the European Directives (Part II) 11:00-12:00 Medical Research with Human Subjects in The Netherlands; The Role of Medical Research Ethics Committies (Prof. Dr. G.H. Koëter, CCMO, Centrale Commissie Mensgebonden Onderzoek) 12:00-13:00 Lunch 13:00-14:00 The Responsibility of the Investigator for a Safe Conduct of Clinical Trials (Part I) (Th. van Iersel, M.D., PRA International B.V.) 14:00-15:00 Patient Groups as Research Partners (C. Smit, Ph.D., EGAN, European Genetic Allicances' Network) 15:00 - end Preparation of Case Studies (Home work)
4 Wednesday March 22, 2017 Subject Good Clinical Practices: Theory and Practice 09:00-12:30 Excursion to the Clinical Research Centre of QPS Netherlands B.V., Groningen Hanzeplein 1 Entrance 53 University Medical Center NL-9713 GZ GRONINGEN Contact person: Dr. W. Tamminga Phone: :30-13:30 Lunch 13:30-14:30 The Responsibility of the Investigator for a Safe Conduct of Clinical Trials (Part II) (Th. van Iersel, M.D., PRA International B.V.) 14:30 - end Preparation of Case Studies (Home work)
5 Thursday March 23, 2017 Subject Good Research Practices and Quality Management: Theory Room: :00-10:15 Quality Management in Drug Research 10:15-10:30 Break 10:30-11:00 Standard Operating Procedures (SOP s) 11:00-11:30 Document Management and Archiving 11:30-12:00 Practical Approaches to Implement GxP's 12:00-12:45 Lunch 12:45-13:45 Misconduct in Biomedical Research 13:45 14:00 Video Research Integrity (Ben Goldacre, M.D.) 14:00 - end Preparation of Case Studies (Home work)
6 Friday March 24, 2017 Subject Good Clinical Practices: Compliance 09:00-10:00 Computer System Validation in Clinical Research (Jean-Paul Eycken, M.Sc., M.B.A. Director FormaliS SA, Diekirch, G-D Luxembourg) 10:00-10:15 Break 10:15-11:15 Quality Assurance Audits by Sponsors (Henk W. Visscher, M. Ph. Sc., M. M. Sc., Auditor Clinical Quality Assurance, GSK Vaccines and Diagnostics) 11:15-12:30 How to Mislead Inspectors during an Inspection? (Jean-Paul Eycken, M.S.c., M.B.A. Director, FormaliS SA, Diekirch, G-D Luxembourg) 12:30-13:15 Lunch 13:15-14:30 Compliance with Good Clinical Practices: Inspections in The Netherlands, Europe and Third Countries (W.R. Verweij, Ph.D., Dutch Health Care Inspectorate Senior Inspector Clinical Trials Ministry of Health, Welfare and Sport) 14:30 - end Preparation of Case Studies (Home work)
7 Monday March 27, 2017 Subject Good Laboratory Practices: Introduction, Theory and Practice Room: :00-10:00 Good Research Practices: GLP (Part I) (Prof. JanHasker G. Jonkman, Ph.D., F.C.P., F.R.Q.A., R. Ph.) 10:00-10:15 Break 10:15-10:30 10:30-11:00 Video GLP Good Research Practices: GLP (Part II) (Prof. JanHasker G. Jonkman, Ph.D., F.C.P., F.R.Q.A., R. Ph.) 11:00-12:30 Good Laboratory Practice (Th. Helder, M. Sc., Former Head of the GLP Monitoring Program in The Netherlands) 12:30-13:15 Lunch 13:15-14:15 Performing a Bioanalytical Study (Part I & II) (M. Kranenborg, Ph.D., QPS Netherlands B.V.) 14:15-17:00 Excursion to the Bioanalytical Laboratories of QPS Netherlands B.V., Groningen Prof. Rankestraat 42 NL-9713 GZ GRONINGEN Contact person: Dr. M. Kranenborg Phone: :00 - end Preparation of Case Studies (Home work)
8 Tuesday March 28, 2017 Subject Case Studies (Presentations by the participants on the course) Discussion 09:00-09:45 Case Study 1 09:45-10:30 Case Study 2 10:30-10:45 Break 10:45-11:30 Case Study 3 11:30-12:15 Case Study 4 12:15 - end Preparation of Case Studies (Home work)
9 Wednesday March 29, 2017 Subject Case Studies (Presentations by the participants on the course) Discussion 09:00-09:45 Case Study 5 09:45-10:30 Case Study 6 10:30-10:45 Break 10:45-12:00 Final discussion 12:00 End of course
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