Academic Positions. Awards/Fellowships
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1 Dr. M. ABDUL KAREEM, Assistant Professor, Dept of Biochemistry, School of Sciences, IGNOU, Maidan Garhi, New Delhi, India Academic Positions Worked as Assistant Professor at King Saud University, Riyadh, Saudi Araybia-2011 Assistant Professor in Biochemistry, School of Sciences, Indira Gandhi National Open University, New Delhi - since May 2011 to Till date Awards/Fellowships Received U.G.C. Dr. D. S. Kothari Post-Doctoral Fellowship Award-2009 Received Post-Doctoral Fellowship from University of SAINS, Malaysia-2010 Received IASc-INSA-NASI Teacher Summer Fellowship for the year 2014 Received Visiting Fellowship from JNCASR, Bangalore for the year Research Interests Cardiovascular and Clinical Biochemistry Computational Biology Signal transduction Ethnopharmacology Projects Completed/ Submitted Evaluation of Role of Nitric Oxide In Atherosclerotic Plaque Development funded by UGC in the year Rs. 15,00,000/- COMPLETED Antiatherogenic efficiency of.on rat model approved by Ministry of Health and Family welfare. For Rs. 30,00,000/- Approved ( ) Invited Reviewer for Journals Cell Biochemistry and function Gene-Elsevier Dementia and Geriatric Cognitive Disorders Fertility and Sterility Human experimental Toxicology International Research Journal of Microbiology Translational Biomedicine Journal Research in Pharmaceutical Biotechnology OMICS-publications Academic Profile PDF (U.G.C. Dr. D.S. Kothari Postdoctoral Fellowship) 1
2 Evaluation of Role of Nitric Oxide In Atherosclerotic Plaque Development, Dept of Biochemistry, Osmania University, Hyderabad-7, India. Ph.D Cardio protective effect of Myristica fragrans seed kernel (Nutmeg) on Isoproterenol induced Myocardial Infarction in rat models. Research guide Prof. K. Lakshmi Devi, Dept of Biochemistry, Sri Krishnadevaraya University, Anantapur , Andhra Pradesh, India. M.Phil Effect of Edible oils on Cardiac and Biochemical parameters in Human volunteers. Research guide Prof. K. Lakshmi Devi, Dept of Biochemistry, Sri Krishnadevaraya University, Anantapur , Andhra Pradesh, India. M.Sc. Biochemistry, from Sri Venkateswara University, Tirupathi, Andhra Pradesh, India. B.Sc., (Biochemistry, Chemistry, & zoology) Srikrishnadevaraya University, Anantapur, India. Continuing Education Completed PG Diploma in Distance Education Pursuing WIPO Intellectual Property Rights Basic Course Laboratory Work Proficiency Models worked Human volunteers Murine models- Wistar and SD strain Rabbit Cell lines - Bovine Endothelial and Neuro2A Memberships Life Time Member in Biotechnology society of India Society for Biological Chemists India Life member in Indian Science Congress Association Conferences Organized: (Organizing committee member) National Seminar on Current trends in Biological chemistry, Dept of Biochemistry, S.K. University, Anantapur, A.P, India List of Resent Publications Books/Chapters: 2
3 1. Contributed chapters for IGNOU Self Learning Material 2. Contributed end of chapter problems for Pearson Global Edition - Appling/Anthony-Cahill/Mathews - Biochemistry: Concepts and Connections Research Publications: 1. Molecular assessment of protective effect of Vitex negundo in ISO induced myocardial infarction in rats. Biomedicine & Pharmacotherapy 92 (2017) Impact factor Trace Element Determination and Cardioprotection of Terminalia pallida Fruit Ethanolic Extract in Isoproterenol Induced Myocardial Infarcted Rats by ICP-MS. Biol Trace Elem Res. DOI /s Impact factor In vivo and molecular docking studies using whole extract and phytocompounds of Aegle marmelos fruit protective effects against Isoproterenol-induced Myocardial infarction in rats. Biomedicine & Pharmacotherapy 91 (2017) Impact facor Antihaemolytic Activity Of Phytochemical Aqueous Extracts Of Pterocarpus Santalinus And Phyllanthus Emblica In Red Blood Cells Of Human Subjects Receiving Chronic Alcohol And Cigarette Smoking. International Journal of Pharmaceutical Sciences and Research. Vol 7, Issue 9, Impact factor Protective effect of nutmeg aqueous extract against experimentally-induced hepatotoxicity and oxidative stress in rats. Journal of Ayurveda & Integratvie Medicine. Oct-Dec, 2013, Vol-4, Issue-4, PubMed. Impact factor M. Abdul Kareem, Genetic Engineering: A new hope. Discovery Science Magazine. August Page S. Althaf hussain, V. Reddy, M. Abdul Kareem, G. Saayi Krushna, K. Lakshmidevi. Cardioprotective effect of HPLC standardized ethanolic extract of Terminalia pallida Fruits against isoproterenol-induced myocardial infarction in albino rats. Journal of Ethnopharmacology. Volume 141, Issue 1, 7 May 2012, Pages Impact factor (2012) 8. Althaf Hussain Shaik*, S.N.Rasool, M. Abdul Kareem, G. Saayi Krushna, P. Akhtar, K. Lakshmi Devi. Maslinic acid protects against isoproterenolinduced cardiotoxicity in albino Wistar rats. Journal of Medicinal Food. 2012,15(8)1-6. Impact factor G. Saayi Krushna, M. Abdul Kareem, VD. Reddy, P. Padma, S. Altaf hussain and K. Lakshmidevi. Aegle Marmelos fruit attenuates isoproterenol induced oxidative stress in rats. J. Clinical Biochemistry and Nutrition. Dec, 2011, 1-6. Impact factor M. Abdul Kareem, G. Saayi Krushna, S. Altaf hussain and K. Lakshmidevi. 3
4 Effect of Nutmeg aqueous extract on hyperglycaemia, hyperlipidaemia and cardiac histology associated with isoproterenol- induced myocardial infarction in rats. Tropical Journal of Pharmaceutical Research. August 2009; 8 (4): Impact Factor G. Saayi Krushna, M Abdul Kareem, K Nagamani and K Lakshmi Devi, Preventive Effect Of Aegle Marmelos Fruit Extract On Isoproterenol Induced Atherogenesis In Rats. IJPT, Vol. 3, Issue No.1, M. Abdul Kareem, G. Saayi krushna & K. Lakshmi Devi: Effects Of Dietary Saturated, Mono Unsaturated and Poly Unsaturated fatty acids On Serum Lipids and Lipoproteins In HumanVolunteers. The Internet Journal of Nutrition and Wellness. 2009; Volume 7, Number G. Saayi Krushna, M Abdul Kareem and K Lakshmi Devi Antidyslipidaemic effect of Aegle marmelos Linn. fruit on Isoproterenol induced myocardial injury in rats. The Internet Journal of Pharmacology Volume 6 Number, G. Saayi krushna, M. Abdul Kareem and K. Lakshmi Devi Cardioprotective and antilipid peroxidative effect of Aegle marmelos against isoproterenol induced cardiac stress in rats. International journal of green pharmacy: vol I, Issue3-4, Oct.- Dec., ISSN Manuscripts Communicated 15. Anti-inflammatory activities of Nutmeg aqueous extract against isoproterenol induced cardio toxicity. Pharmaceutical Biology. (Under review) 16. Biochemical and Biophysical changes during isoproterenol induced myocardial infarction in rat models. Toxicology letters. (Communicated) 17. Molecular Docking Evidences for the Inhibition of inducible Nitric Oxide synthase activity by Natural compounds. J of Mol Modeling (communicated) 18. Biochemical signaling of oxidative stress elevated Nitric oxide in high fat fed SD rats (Drafting) Conferences/Symposiums 1. Drug discovery, Development - Challenges and Limitations : A case study. Delivered Invited talk at National Workshop on Applications of Chemiinformatics- Big DATA in Drug discovery. On 25 th, March, 2017 at Sri Venkateswara University, Tirupathi. 2. Molecular Modelling And Docking Studies For The Assessment Of Anti- Inflammatory Efficiency Of Two Ancient Herbal Extracts During Isoprotenol 4
5 Induced Cardiotoxicity. On 13 th -14 th Feb, 2017 at Jamia Millia Islamia University, New Delhi. 3. Experimental Induction of Oxidative stress during predisposed Hyperlipidaemia leads to enhanced Nitric Oxide (NO) signalling. National seminar on Anthropology and health is 5 January Inhibition of inos expression could be a potential therapeutic target for CVDs at Dept of Anthropology, Delhi University. 5. Paper presentation on Homology modelling and Molecular docking studies against inducible nitric oxide synthase at Asian Plant Science conference held on Nov 1-3 rd, 2014 at Nepal. 6. Presented paper as Co-author at IIS CME & National Seminar on Immune interface of Host Pathogen interactions on 7 th and 8 th December, 2013 in the Department of Biochemistry, Andhra University, Visakhapatnam. Peptide based strategies to combat sepsis. 7. Current advances in Biotechnology and Medicine, Organized by ILBS and BSI New Delhi, Institute of Liver and Biliary Sciences, New Delhi on 24 th & 25 th, Feb, Computational Approach for Lead Optimization in Drug Discovery, DBT funded, SV College (Delhi University) in association with Schrodinger, Inc. USA on 22-23, Dec, th Annual Convention of Association of Biotechnology and Pharmacy, Dec, 7-9, 2011, Coimbatore th, Annual Meeting of SBCI, th Nov, 2011, CIMAP, Lucknow. 11. Effect of Myristica fragrans (Nutmeg) aqueous extract on Lipidprofile, Lipidperoxidation and Marker enzymes in Isoproterenol induced Myocardial infarction in rats, 77 th SBCI, conducted by IIT Chennai, India from th Dec, Protective effect of Nutmeg aqueous extract on Isoproterenol induced Cardiotoxicity in rats, Asian symposium on medicinal plants, spices and other natural products (ASOMPS) XIII, conducted by IICT, Hyderabad, India from 3-6 th Nov, Protective role of Asparagus racemosus root ethanolic extract on Isoproterenol induced cardiac stress in rats. International conference on Plant Biotechnology and 5
6 Molecular Biology, Kakatiya University, Warangal, A.P, India, from th Aug, Cardioprotective effect of Eagle marmelos on isoproterenol induced rats at International symposium on Medicinal plants and Herbal products in Srivenkateswara University, Tirupati, from 7-9 th march, Antioxidant properties of nutmeg: against isoproterenol induced Cardiac stress in rats at AP akademi of sciences annual convention and national symposium on SCIENCE IN THE 21 ST CENTURY, in SK university from 5-6 th feb, Athero protective effect of Aspartagus racemosus on Isoproterenol induced cardiac stress in rats at 76 th SBCI seminars at S.V. University, Tirupati Nov, National Seminar on Current trends in Biological chemistry Effect of aegle marmelos(l.) On isoproterenol induced hyperlipidemia in rats, conducted by the Department of Biochemistry, Sri Krishnadevaraya University, Anantapur, India held on December, 17 th and 18 th AT 75 th SBCI annual meeting, at New delhi, India, Effect of various dietary oils on serum nitric oxide and lipid peroxidatiion levels in human volunteers, from to National symposium on Biotechnology-trends & Perspectives held in the Sri Krishnadevaraya University, Effect of edible oils on Cardiac and Biochemical parameters in human volunteers at SK University, from February, 2006 Trainings and Workshops Participated 1. Participated in Protein Folding training at Super computer facility, IIT-Delhi from th Aug, Creativity in Designing and development of Assessment methods by National Centre for Innovation in distance Education 20 th 22 nd Short term training on Bioprospecting of Medicinal plants. Organized by TERI, New Delhi, sponsored by DBT, India. From 6 th 18 th Creative use of Technology and Tools for Teaching and Learning by National Centre for Innovation in distance Education 20 th -21 st
7 5. Creativity in Design and development of SLM by National Centre for Innovation in distance Education 22 nd -23 rd Computational Approach for Lead Optimization in Drug Discovery, DBT funded, SV College (Delhi University) in association with Schrodinger, Inc. USA on 22-23, Dec, Induction programme for newly joined faculty, STRIDES, from 21 st 25 th Nov Development of online Programmes by IUAC, IGNOU on 17 th & 18 th Aug One day Workshop on Energy Conservation and Renewable Energy, to be held on April 22, 2013 by SOET, IGNOU. 7
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