UNIVERSITY OF CALCUTTA

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1 UNIVERSITY OF CALCUTTA Re: Updating University Website ACADEMIC DEPARTMENT FACULTY ACADEMIC PROFILE/ CV Full name of the faculty member: Indu Bhusan Chatterjee Designation: Professor and Joint Coordinator, Department of Biotechnology and Dr. B. C. Guha Centre for Genetic Engineering and Biotechnology Specialisation :Biosynthesis and function of vitamin C; cigarette smoke induced various diseases including cancer and their prevention.. Contact information : Residence: 719, Lake Town, Kolkata , Phone (Res): ;(M) ; Ibchatterjee123@gmail.com Academic qualifications: B.Sc (Hons) Chemistry Scottish Church College, Calcutta University M.Sc (Applied Chemistry) Calcutta University D.Sc (Applied Chemistry) Calcutta University Positions held/ holding:

2 Joint Coordinator, Department of Biotechnology and Dr. B. C. Guha Centre for Genetic Engineering and Biotechnology; INSA Honorary Scientist Research interests: Cellular and molecular mechanisms of initiation of cigarette smoke induced cancer of the lung, renal pelvis, cardiovascular disease, chronic obstructive pulmonary disease, myelodysplastic syndromes, loss of structure and function of serum proteins and hemoglobin, cataract formation and prevention of the aforesaid diseases by vitamin C. Research guidance : Number of researchers awarded M.Phil/ Ph.Ddegrees : About thirty Number of researchers pursuing M.Phil/ Ph.D : Two Projects : Completed projects : Current projects : 1. Cigarette smoke induced cancer of the renal pelvis and its prevention 2. Cigarette smoke induced lung cancer 3. Identification of a predictive biomarker in serum of smokers susceptible to Chronic Obstructive Pulmonary Disease Select list of publications: (Total publications: 99) a) Journals: Recent publications (last five years) 1. Das A, Dey N, Ghosh A, Das T, Chatterjee I. B. NAD(P)H: Quinone Oxidoreductase 1 Deficiency Conjoint with Marginal Vitamin C Deficiency Causes Cigarette Smoke Induced Myelodysplastic Syndromes. PLoS ONE, May Volume 6 Issue 5 e20590 (2011). 2. Dey N, Chattopadhyay D J and Chatterjee I B. Molecular mechanisms of cigarette smoke induced proliferation of lung cells and prevention by vitamin C. J Oncology, Article ID , doi: /2011/ (2011). 3. I B. Chatterjee and Arunava Ghosh, Black tea and prevention of cigarette smoke induced lung damage. A chapter in the Book Tea in Health and Disease Prevention. Editor: Victor R. Preedy, Academic Press, pp (2011). 4. Arunava Ghosh, Aparajita Choudhury, Archita Das, Nabendu S. Chatterjee, Tanusree Das, Rukhsana Chowdhury, Koustubh Panda, Rajat Banerjee, Indu B. Chatterjee. Cigarette smoke induces p benzoquinone albumin adduct in blood serum: Implications on structure and ligand binding properties. Toxicology, 292, 78 89(2012). 5. Das A, Dey N, Ghosh A, Das S, Chattopadhaya D J, Chatterjee I B., Molecular and cellular mechanisms of cigarette smoke induced myocardial injury. PLoS ONE, volume 7, e44151, (2012). 6. Neekkan Dey, Shinjini Ganguly, Indu B. Chatterjee, Dhrubajyoti Chattopadhyay Molecular mechanisms of cigarette smoke induced proliferation of human lung cells and its prevention J Thoracic Oncology, Volume 7, Number 11, Supplement 5, (2012). 7 Arunava Ghosh*, Shinjini Ganguly*, Neekkan Dey, Santanu Banerjee, Archita Das, Dhruba J. Chattopadhyay,and Indu B. Chatterjee (2015). Causation of Cigarette Smoke Induced Emphysema by p Benzoquinone and Its Prevention by Vitamin C. Am J Respir Cell Mol Biol 52: (2015). 8 A. Das, I. B. Chatterjee. Conjoint Deficiency of Vitamin C and NQO1 Causes Cigarette Smoke Induced MDS. In Nutrition and diet in leukemia and blood disease therapy. Eds.

3 Ronald Watson & Daruka Mahadevan, Wageningen Academics, chapter 7, pp (2015). 9. Arunava Ghosh a, Santanu Banerjee a, Amrita Mitra b, Monita Muralidharan b Bappaditya Roy a, Rajat Banerjee a, Amit Kumar Mandal b, Indu B. Chatterjee Interaction of p benzoquinone with hemoglobin in smoker s blood causes alteration of structure and loss of oxygen binding capacity. Toxicology Reports, in press, Patents : Membership of Learned Societies: Indian National Science Academy, West Bengal Academy of Science & Technology Patents granted Patent 1: A process for Isolation of a major harmful oxidant from Cigarette Smoke The technology has been protected through patent in India as well as in other countries whose details are as below: Indian Patent Application No.: 701/DEL/2001; Patent No , dated February 28, 2009 (IF) Priority Date: SN Country CC Application No Patent No. Status 1 Canada CA IF 2 China CN ZL IF 3 European Union EP EP RO/EP/NP/IF 4 Austria AT EP IF/EP DESIG 5 Germany DE DE IF/EP DESIG 6 Spain ES EP IF/EP DESIG 7 Finland FI EP IF/EP DESIG 8 France FR EP IF/EP DESIG 9 Great Britain (UK) GB EP IF/EP DESIG 10 Italy IT EP IF/EP DESIG 11 Portugal PT EP IF/EP DESIG 12 Turkey TR TR T4 IF/EP DESIG 13 Japan JP IF 14 Korea KRC IF

4 15 USA USA 10/ IF 16 USA (dvn) USB 10/ DIV IF 17 WIPO/ PCT Appln WO PCT/IN02/00019 RO Patent 2: IF= patents IN FORCE Activated charcoal filter for effectively reducing para benzosemiquinone from the mainstream cigarette smoke. The technology has been protected through patent in India as well as in other countries whose details are as below: Indian Patent Application No.: 1025/DEL/2001; Patent No (IF), dated 17/09/2015. Date: Priority SN Country CC Application No Patent No. Status 1 Canada CA IF 2 European Union EP EP RO/EP/NP/IF 3 Germany DE EP IF/EP DESIG 4 Spain ES EP IF/EP DESIG 5 France FR EP IF/EP DESIG 6 Great Britain (UK) GB EP IF/EP DESIG 7 Greece GR EP IF/EP DESIG 8 Italy IT EP IF/EP DESIG 9 Portugal PT EP IF/EP DESIG 10 Japan JP IF 11 USA US 10/ IF 12 WIPO/ PCT Appln WO PCT/IN02/00020 RO IF= patents IN FORCE Patent # 3 A method for prevention of cigarette smoke induced protein oxidation Inventor: Indu Bhusan Chatterjee

5 Assignee: CSIR India: Patent No , dated November 11, 2011 Patent # 4 An ELISA device for the measurement of serum anti p benzoquinone antibody And a method of making the same. Inventor: Indu Bhusan Chatterjee and Santanu Banerjee Indian Patent Application No. 1049/Kol/2015, publication date 06/11/2015 Invited lectures delivered : Awards : 1. Awarded Amulyaratan Prize of Calcutta University in Awarded Platinum Jubilee Lecturer in Biochemistry & Molecular Biology, Indian Science Congress, Awarded B. C. Guha Lecture Award from the Indian National Science Academy in Awarded Life Time Achievement Award in Biochemistry from Kalyani University in Received Eminent Teacher Award of Calcutta University in Received B. C. Guha Lecture Award from Indian Science News Association Acharya P. C. Ray Memorial Lecture Award from PULMOCON, India (2011) 8. INSA Honorary scientist 2006 till date 9. Ava Maity Meomorial Lecture Award,_Asiatic Society Barclay Medal, Asiatic Society, 2014 Other notable activities : Instrumental in establishing Dr. B. C. Guha Centre for Genetic Engineering and Biotechnology of Calcutta University and Founder Coordinator of the Centre