The Liver Connection: How a Healthy Liver lmpacts Children on the Autism Spectrum while Doing Heavy Metal and chemical Detoxification

Transcription

1 The Liver Connecion: How a Healhy Liver lmpacs Children on he Auism Specrum while Doing Heavy Meal and chemical By Sreplanie Ray, Timi Wilken, Teri Woods, CCN, esearc/ wihin he CH, LlSA field lfauism Specrum Disorder (ASD) illusraes ha biomedical ineruenions conribue o A measurable deuease in auisic,/mpoms.' These children haue high leuels of heauy meals, chemi ASD kids cals, uiruses, yeas, baceria and/or p(rasies. are qpically pu on deoxificaion proocols which can haue aduerse ffics on heir sensiiue sysems, frequenly resuling in a "bealing uisis" or uorsenirg of heir sympoms. ino adipose issue where hey may say for many years. The brain and he endocrine glands are fary organs, and are common sies for fa-soluble oxins o accumulae. Sy-poms may include brain dysfuncion, hormonal imbalances and adrenal gland exhausion. Environmenal Toxins Cause an lmbalance in Phase and ll Funcion Making he Deox Process Much More Challenging Phase Liver Deox Pahway Convers a Toxic Chemical lno a Less Harmful Chemical This is achieved by various chemical reacions; such as oxidaion, reducion and hydrolysis. Excessive amouns of oxic chemicals such as pesicides can disrup he P45 enzyme sysem of his pahway by causirg over aciviy or 'inducion'. The meabolies from his incomplee deoxificaion process are poenially more harmful han heir original oxic compounds. is imporan for healh ha hese oxic compounds are no allowed o build up as hey conribue o oxidaive sress. : For children wih ASD, oxidaive sress can presen as low levels of gluahione and meallohionein, hypersensiiviy o environmenal oxins, food sensiiviies, immune dyfuncion, low somach acid, increase in candida, and inflammaion in he gasroinesinal rac and brain. Subsances ha cause over aciviy duri.g Phase are caffeine, dioxin, sauraed fas, organophosphorus pesicides, pain fumes, sulfonamides, exhaus fumes, and pharmaceuicals. Research shows ha when Phase deox pahway is more efficien han Phase, lead o a higher risk for adverse healh effecs when exposed o environmenal oxins."'v/hen here is an imbalance or he liver is overburdened, he liver's abiliry o filer becomes impaired. Many of hese oxins, heavy meals & chemicals are fa soluble and incorporae hemselves Phase ll Liver Deox Pahway This is called he conjugaion pahway, where he liver cells add anoher subsance such as cyseine, glycine or a sulfur molecule o a oxic chemical or drug, o render i less harmful. The conjugaion molecules Each child is biochemically unique, requiring an individual approach o deox. One hing ha remains consisen among all ASD children is he significan role a healhy liver plays in rebuildi.g overall healh and increasing neurological funco -'' ion. Sudies show ha heir liver funcion is impaired'' prior o a deoxificaion proocol and becomes furher compromised when given wesern medicaions." This paper discusses he benefis of preparig he liver, in paricular, Phase and Phase liver deoxificaion pahways prior o iniiairg deox. Resoring liver meabolism significanly increases he uilizaion of oher biomedical reamens leading o a greaer qualiy of life for ASD children and heir families. (l7i 4,E'delsorrSB'CanrorDS.Auisnr:xerrobioicinf']ences.'oxicolndHealh.l998Ju.Aug;l4(4):55 l9l-.16. " Mecl Hvporhescs. 2 Scp;55(-3): A, Chauhan Janak L, Gaylor children rvih iruisrr. [)i\l[[): 15585;7(r Explorc! Vohune 17, Nunber 5, 21

2 are aced upon by specific enzymes o caalyze he reacion sep. Through conjugaion, he liver is able o urn drugs, hormones and various oxins ino excreable subsances. The oxin or drug becomes waer-soluble, so i can hen be excreed from he body via waery fluids such as bile or urine. Vhen Phase is slower han Phase, as found in ASD children,'.' hese children experience cold or flulike sympoms, rashes, irriabiliy, increase in anxiey, OCD, regression in skills when hey iniiae deoxificaion proocols wihou preparirg heir liver for deoxificaion. "Leaky Gu", Yeas, Baceria and he Liver Addiional pressure is pu on he liver when "leaky gu" is presen. Large food molecules, baceria, fungi, parasies and heir byproducs can pass sraigh ino he bloodsream and be presened o he liver for deoxificaion. The overload of oxins and heavy meals in he environmen increases he processing of meabolic wases creaed by cell and organ aciviy which conribues o furher sress on he liver. " \fhen he dumpi.g of inesinal oxins occurs on a regular basis, he liver becomes sauraed. can no longer deoxif he poisons, and hey are reurned o he blood for circulaion. This leaves he door open for yeas and baceria o become sysemic. Sympoms of "leaky gu" in ASD children include: food sensiiviies, bloaing, rashes, irriabiliry, poor concenraion, malabsorpion, and undigesed food in sools, menal and behavioral regressions afer eaing cerain foods. lmmune Sysem Mos children wih auism have a subsanial immune abnormaliy of some ype.'- "Leaky gu" acivaes he immune and auoimmune sysems. The immune sysem makes anibodies agains he larger molecules because i recognizes hem as invading subsances. Due o his hyper-simulaed sae, excessive inflammaory chemicals like hisamine are produced, and in some cases, auo anibodies. When he immune sysem is overloaded on a regular basis, i is spread hin over a wide array of erriory defendi.g he gu, cleaning he blood, fighing inflammaion, and warding offpahogens. f hisamines become oo high, ASD children presen wih some of he following: hyperaciviry, compulsive behaviors, depression, inense mood swings, perfecionism, srong wills, explosive anger, anxiery, hair pulling, lack of focus, scriping, high libido, inappropriae gigglig, aggression, change in bowel move- a craving for sal, frequen urinaion and rashes. From here he lymphaic sysem will aemp o collec and neuralize he oxins, bu unable o send he oxins o he liver, he body essenially becomes oxi c.'" mens, Ammona and he Liver Liver failure is associaed wih high ammonia levels.'- A wide range of he oxic subsances produced in a oxic bowel is sen on o he liver, which is he body's primary de oxificaion sie. Durig he digesion of proeins, a number of harmful baceria, includi.g Closridia, Eubaceria, and Peposrepococci, produce oxic ammonia in he gasroinesinal rac. is he resul of a perfecly normal process. A healhy liver deoxifies he ammonia by urning i ino urea, which is passed ou of he body ino he urine. Vhen leaky gu syndrome is presen, he ammonia remains unprocessed and eners he bloodsream, invadi.g he cenral nervous sysem. This is he causal facor of many dangerous sympoms, such as minimal hepaic encephalopahy and he brain is affeced.'' n children on he auism specrllm we see hese signs of excess ammonia; lehargy,, seizures, aaxia, unclear hinking, exreme sleepiness, "spinning Thoughs" i.e. repeaig houghs, OCD rype behavior, forgefulness, rouble concenrai.g, confusion, and agiaion. Muli srain probioics are helpful in reaing an unhealhy liver bv prevening he absorpion of ammonia from he colon; once again indicaing he srong relaionship bewee n he liver and he gu."' \(/he n probioics reach he inesines, hey are welcomed by he friendly baceria as a good food source. Through fermenaion, he baceria urn 'fhis has he naural probioics ino lacic and aceic acids. effec of reducing he ph level of he large inesine, makig i far more acidic. When a high level of acidiy is presen in he inesines he ammonia remains in is ionized form. n his form, i is no passed on o he liver or diffused ino general circulaion hrough he blood. This reduces he oxic load on he liver and reduces ammonia levels hroughou he bodv, includig he brain. ph An acidic condiion robs he body of oxygen and enables harmful pahogens o hrive. f young paiens are oo acidic, hey carl no assimilae nuriens efficienly from he foods hey ea or he supplemens hey ake. The body will be forced o pull essenial miuerals like calcium, ffignesium, poassium and sodium from he organs and bones o neu ualze he acids. ToxicollndHealhlgg8Jul-Aug;14(4): Auism:xenobioicinfluences.PMD: "LindoKO,JarvelainenHA.MeabBrainDis.25 Dec. 2(4) Chroniciyr,"-1. endooxin exposure: an animal model in experimenal hepaic encephalopahv. " sudies done bv Reed Varren Ph.D. ar Uah Sare Universiry, Sudhir Gupa MD Ph.D., a clinical immunologis a he Universiy of Califbrnia ar rvine l\{edical School. and ohers indicae 'n D. Ron Grisanri hrpi//*.d.e.imni.com/mucosalto2barrier.hm ': Limied clpaciv fbr ammonia renroval bv brain in chronic liver failure.-aboraorv of Neurobiology, C.nio de nuesiigacion Principe Felipe, Fundacion Valenciirna de nvesieaciones Biomedicas, Avda del Saler, l(r, Camino de las Morcras laculose in he reamen of minimal hepaic encephalopahv in ras. Jia L, Zhang MH. f)eparmen 4613, Valenc*ia, Spain. '"Compariion of probioi.. "ni of Digesive Diseass, Affiliaed Fire Peopli's Municipal Hospial, Guangzhou Medical College, Guangdone, China. "Corrparison of probioics and laculose in he-reamen of minimal hepaic encephalopahy in ras. Jia L, Zhang MH. Deparmen oldigesive Diseases. Afliliacd Firs People's lv4unicipal Hospil' Guangzhou Medical College, Guangdong, China. ExDlore. l'ohnnr 7, lyumbar 5, 21

3 As children drain acidic wase hrough heir urine he inner errain comes ino balance. A healhy firs morning urine ph should be wihin he range of wih a healhy saliva ph of '" Saliva ph represens wha he body is holding or ph homeosasis. The firs morning urine ph represens he meabolic wase we are able o excree. An alkaline firs morning urine ph indicaes liver congesion; or a holdllg ono oxins. Teslilg he firs morni.g urine ph is an effecive way o see if he body is able o ge rid of acidic wase efficienly. A he beginning of herapy, he majoriry of ASD children es consisenly wih high firs morning urine ph, over 6.2, and low saliva ph, less han 6.8, which indicaes liver congesion and an over acidic condiion. Sulfhydryl group chelaors and several wesern medicines have been rroed o alkahze firs morning urine.-'' Viamin & Minerals Deficiency of viamins and minerals are prevalen wihin he auism communiy wih viamin 8-6, B-2, zinc, magnesirm and calciurn being discussed he mos. As OAT, (Organic Acid Urinary Tess)" show, when liver funcion improves and he ph have come ino healhy range many children are able o uilize nuriens from food and supplemens more efficienly. Parens repor a need o reduce cerain mega doses of viamins and minerals when his occurs. Choleserol, Fay Acid Meaholism and he Liver Two common facors in auism specrum disorder are low levels of choleserol and an impaired fary acid meabolisnr.' Sudies show children wih auism, are low in choleserol -no due o a limied inake bu raher an inabiliry o make choleserol. Choleserol is produced by he liver and oher organs in he body via a complex meabolic pahway. The choleserol ha he liver produces is vial o srenghenig he membranes of each and every cell in he body. Bile acids, a by produc of he choleserol meabolism, are made in he liver and are he "deergens" of fa meabolism; hey are also signaling molecules ha provide he body wih k.y informaion abou he sae of he liver.'o Sympoms of fay acid deficiencies in ASD children are skin condiions (dry, bumpy, eczema), diarrhea, faigue, aggression, failure o hrive, eaing disorders, excessive hirs, immune deficiency, hyperaciviy, and impaired wound healing.'' Organic Acid Urinary Analysis. Developed o assess efficienry of cellular ene rgy producion, meabolic oxiciry problems/deoxificaion funcions, funcional viamin, mineral and amino acid deficiencies and neuroransmier meabolism. n addiion, his analysis provides imporan informaion abou clinically significan gu flora imbalances by deecing elevaed levels of meabolic wase producs from baceria and yeas. A Case Sudy: 1 year old girl, presened wih ypical sympoms of auism, oo recepive language or communicaion, didn' pl^y wih oys, ro poining, no babble, apraxic, no back and forh ineracions, bowels were impaced requiring a daily enema, elevaed liver enzymes, exreme eczema - she looked like a burn vicim. Child is pu on a biomedical heavy meal deoxificaion proocol (TD DMSA) wih ou addressing liver funcion. Six monhs on his proocol and a baseline OAT is performed. See resuls below r l r r r / r 'l hp://healh.groups.vahoo.com/group/bioraynauraldeox -'r Grea Plaines Laboraory Manageme nr of Heaw Meal Deox 8-]88-383hrp://ww.greaplainslaboraorr,.com'Genor'aDiagnosics w.genovadiagnosics.com..'FawAcidsinDyslexi.-,Dyspria' hcauisicspccrunralcxarrdrarichardson'd.phil(oxon),pcge-,bileacids'receporkevinregeneraingliversbyruh '" ' 23 Tinohl, Rav OMD LAc The ph [)r'spraxia, A[)HD rncl he Auisic Explrc! Volune 17, Nunber 5, 28 Specrum Alexandra Richardson, D.Phil (Oxon), PCGE

4 Child's firs morning urine ph is 6.8 and saliva is 8., boh severely ou of healhy range. Liver Life is incorporaed ino her TD DMSA heavy meal deoxificaion proocol sarirg wih one drop of Live r Life 2x per d^y. Nex d^y, she has bowel movemen wih ou inducing for firs ime in several monhs. Daily independen bowel movemens coninue on Liver Life and ph s come ino range, eczemacompleely resolves, liver enzymes come ino range. Three monhs afer inroducing Liver Life anoher OAT is performed. OAT resuls show ha Liver Life enabled her o decrease yeas overgrowh, improve he Krebs cycle, and regulae excessive fary acid oxidaion, increase gluahione levels as well as increase nurien absorpion. The excessive levels of Ascorbic indicae ha he high doses of nuriional supplemens can be lowered, she is assimilaing nuriens from her food and supplemens more efficienly. Case Oucome: Paien, now 3 years old, is Neural Typical, very healhy, and advanced in all areas, "currenly alking circles around oher children her age". Mom says: "Liver Life enabled me o do he reamens ha my daugher needed. was exacly wha we were lookirg for. " Sympomology commonly repored when Liver Funcion is compromised in ASD Children: Yeas and bacerial infecions i Food inolerances/allergies Seasonal allergies/high hisamines Significan decrease in absorpion of nuriens from food and supplemens Decrease in verbal and non-verbal communicaion skills mpaired digesive funcion Decreased cogniive abili.y Lack of focus Sensory overload Emoional ouburss Vhen he liver funcion has been resored in ASD children; heir docors, parens and eachers repor: i of he chelaor. Ve see and hear of cell wall as he yeas dies)." "regressing" and sympoms appear as saed above. This givirg subsances ha feed he process is reversible by liver allow i o do he job naure inended: eliminae, manufacure, and sore. -proving liver funcion in ASD children increases he efficacy of allopahic and well. OMD Explore! For rhe Professional, Volumel5, Number How o improve he livers' srucure and funcion: Foods Whole organic foods conain 3 imes " more nuriens han processed foods. These nuriens provide energy and maerials for our cells o rebuild. \7hen liver srucure and funcion are impaired or in he body become aggravaed, oxins "back up" in he body and signs of a healing crisis ensue. n children on he specrum his has been seen as Ray, L.Ac. wih many differen chela- ized, he poisons redisribue ino o/erwise heahhy issue and coninue o cause cell deah, dyf""cion or muaion. This produces he sympoms ofa 'healing misis', which is really a misnomer for eiher a crisis ofpoor cnse managemen, he disurbing chemical ineracion of mercury wih AmmoniA, acue infecions due o he wihdrawal of he animicrobial,ffio of uarious heauy meals, or candida die-off rympzml (which are acually a sudden release of he heauy meals bond ino he yeas congesed, all sysems Ti-ohy success ors. Success is equal o how well he organs of eliminaion are prepared and suppored during hese inervenions. "f more poison is mobilized han can be exueed or neural- How does his help wih heavy meal and chemical deoxificaion? o o'26 more focus improved comprehension abiliry o do school work more calm consisency in day o day abiliies beer absorpion of nuriens from foods able o decrease mega doses of viamins and minerals decrease in food sensiiviies healhier bowel movemens n order o mainain opimum efficacy of he chosen chelaor, he preparaion of he organs associaed wih deox is more i-poran han he mehodology Skin rashes/condiions (i... eczema) as increased communicaion appropriae speech $(/hile liver funcion is he primary subjec of his paper - all oher organs of eliminaion mus also be addressed. Disruped sleep inegraive reamens beer social skills 5 '- Ea plenry of fresh fruis and lighdy cooked vegeables especially dark green, lr& vegeables and orange, yellow, purple, and red colored fruis and vegeables hey conain living enzymes, fiber, viamin C, -naural anibioic subsances, phfo-nuriens and hey are excellen suppor for Phase deox pahway. Ea sulfurous veggies (broccoli, cabbage, ec.) - hey assis Phase deox pahway Ea foods ha increase gluahione levels in he body. fuparagus, waermelon and broccoli are good sources of gluahione while papayas and avocados help he body o produce gluahione. Supplemen digesive enzymes o assis absorpion of nuriens needed o resore he alkaline reserve, decrease he sress on he liver and opimize digesion. hrrps://w.bioray2.com/uploads/organicfoodsarehealhier.pdf Exp/ore. Vo/ume 17, Nurnber 5, 28

5 How o improve he livers' srucure and funcion: Remedies 8c single ingrediens - Liver Life is a food for he Liver. Liver Life" is a cerified organic blend of live medicinal mushrooms and herbs, a synergisic formula ha resores healhy liver funcion and opens Phase and deox pahways. There is a common misconcepion regardig he use of medicinal mushrooms when candida is presen. The high polysaccharide conen in some medicinal mushrooms makes hem a viable remedy in reaing candida. Each qualiry ingredien lised below conains valuable properies ha conribue o "feeding" he liver. Coriolus Versicolor simulaes he anigen-presenirg cell funcion of macrophages which help o simulae and srenghen overall immune funcion. enhances he cyooxic aciviry of naural killer cells, conains powerful anibacerial and anioxidan capabiliies. Ganoderma Lucidum (Reishi) - modulaes he immune sysem, inhibis hisamine release, resores homeosasis, enhances naural killer cell aciviry, and increases he produc- ion of inerleukin and inerferon. Also, has an ani-inflammaory, anibacerial, anifungal, aniviral, and anioxidan properry. medicinal mushroom also filers he blood by engulfing and Grifola (Maiake) - conains unique bea-glucan called D-fracion which proecs he body by simulaing immune cells, proecs liver issue from environmenal oxins, inhibis boh he accumulaion of liver lipids and he elevaion of serum lipids, acivaes macrophages and aids he body in desroyirg viruses, bace ria, yeas, heavy meals, polluans adaping o physical and emoional sress. Himmemasuake (Agaricus Blazei) - modulaes he immune sysem, suppors digesive healh, speeds up he healing process, and inhibis hisamine producion. This and bis of dead issue. Red Roo (Jersey T.") - assiss in he removal of oxins, issue wases, acids, and cellular debris. improves blood circulaion, helps o deconges, drain and ranspor lymph fluids. This herb also has ani inflammaory anispasmodic, and animicrobial properies. Milk Thisde Seeds - preven peneraion of liver oxins ino he inerior of he cell, decongess he liver, preven he depleion of gluahione, decrease inflammaion, purifies he blood, proecs he kidneys, proecs agains free radical damage. Olive Leaf - prevens pahogens from reproducing and creaing more microbes wihin he body and has anioxidan and animicrobial properies. Olive leaf increases he flow of bile and onifies he liver. } End Noe We have seen hundreds of cases where children on he specrum are pu on a moderae o exensive heavy meal deoxificaion proocol wihou suppor for he organs of eliminaion. Many parens repor heir children are unable o follow hrough wih he recommended proocol due o significan sympoms of a "deox reacion". Valuable healirg ime is los. Monioring ph values is easy for boh he paren and child; i's a ool ha parens can use o "see" if heir child is draining acids. Resoring he liver's meabolism is a simple, ye profound sep in a successful deox proocol for ASD children; improving healh and vialiqy while insurin g a gradual and effecive deoxificaion. s{ Call BioRa;,, nc. ( (wnv.biorav2.com)or Scienific Bio-Logics (714) (w.sblogics.com) o order Liver Lif'e and oher BioRav producrs. Liver Life. For he safe and naural revializaion of he liver. PURE AND SMPLE SNCE BioRay nc. (949) Explore. \/olurne 17,,Ynrber 5, 28