0091 Organix Comprehensive Profile - Urine

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1 Accession #: Order #: Reference #: H Dae Colleced: Dae Received: Dae of Repor: 06/04/ /05/ /13/2014 Paien: Dae of Birh: 03/27/1971 Telephone: Ordering Physician: NourishBalanceThrive h S Ap 1 Oakland, CA Age: Sex: Reprined: Commen: 43 Female Fax: Mehodology: LC/Tandem Mass Specroscopy, Colorimeric Organix Inerpreaion Inerpreive Guides are downloadable a: CLIA ID# 11D Tesing Performed by Genova Diagnosics, Inc Corporae Way, Duluh, GA Florida Clinical Lab Lic. # Laboraory Direcor: Rober M. David, PhD

2 Accession #: Order #: Reference #: H Dae Colleced: Dae Received: Dae of Repor: 06/04/ /05/ /13/2014 Paien: Dae of Birh: 03/27/1971 Telephone: Ordering Physician: NourishBalanceThrive h S Ap 1 Oakland, CA Age: Sex: Reprined: Commen: 43 Female Fax: Mehodology: LC/Tandem Mass Specroscopy, Colorimeric Summary of Abnormal Findings Findings Inervenion Opions Common Meabolic Associaion Fay Acid Meabolism Adipae Carniine, B2 Fay acid oxidaion Carbohydrae Meabolism Pyruvae Lipoic Acid, B1, B2, B3, B5 Glucose oxidaion L-Lacae CoQ10, Lipoic Acid, B1, B2, B3, B5 Glucose oxidaion Energy Producion Markers Cis-Aconiae Arginine Renal ammonia loading Isocirae Arginine Renal ammonia loading a-keogluarae Malae CoQ10, Lipoic Acid, B1, B2, B3, B5 CoQ10 Ciric acid cycle ATP producion Hydroxymehylgluarae CoQ10 HMG-CoA reducase inhibiion B-Complex Viamin Markers Xanhurenae B6 Impaired Trypophan meabolism ß-Hydroxyisovalerae Bioin, B2 Impaired Isoleucine meabolism Mehylaion Cofacor Markers Formiminogluamae Folic acid Terahydrofolae insufficiency Neuroransmier Meabolism Markers Vanilmandelae Very Low 5-Hydroxyindoleaceae Kynurenae Tyrosine, Phenylalanine --- B6 Epi- & Norepinephrine urnover inhibiion Seroonin urnover simulaion Recepor anagonis Oxidaive Damage and Anioxidan Markers CLIA ID# 11D Tesing Performed by Genova Diagnosics, Inc Corporae Way, Duluh, GA Florida Clinical Lab Lic. # Laboraory Direcor: Rober M. David, PhD

3 Accession #: Order #: Reference #: H Dae Colleced: Dae Received: Dae of Repor: 06/04/ /05/ /13/2014 Paien: Dae of Birh: 03/27/1971 Telephone: Ordering Physician: NourishBalanceThrive h S Ap 1 Oakland, CA Age: Sex: Reprined: Commen: 43 Female Fax: Mehodology: LC/Tandem Mass Specroscopy, Colorimeric p-hydroxyphenyllacae Viamin C, Viamin E 8-Hydroxy-2-deoxyguanosine Viamin C, Viamin E Increased cell urn over DNA oxidaion produc Deoxificaion Indicaors Glucarae N-aceylcyseine, Hepaic suppor Hepaic Phase I and II deox a-hydroxybuyrae Pyrogluamae Sulfae N-aceylcyseine, oher sulfur conaining amino acids N-aceylcyseine, oher sulfur conaining amino acids Anioxidans and removal of oxican or oxidan sress source Gluahione demand Gluahione wasing Acue deox or oxidan sress Bacerial - General Hippurae Glycine Hepaic Phase II conjugaion p-hydroxyphenylaceae Probioics Inesinal Bacerial Overgrowh Indican Probioics Inesinal Bacerial Overgrowh L. acidophilus / general baceria D-Lacae Non D-lacae-forming Probioics Inesinal bacerial overgrowh (L. acidophillus) Closridial Species No Abnormaliy Found Yeas/Fungal D-Arabiniol Anifungals Yeas Overgrowh CLIA ID# 11D Tesing Performed by Genova Diagnosics, Inc Corporae Way, Duluh, GA Florida Clinical Lab Lic. # Laboraory Direcor: Rober M. David, PhD

4 Accession #: Order #: Reference #: H Dae Colleced: Dae Received: Dae of Repor: 06/04/ /05/ /13/2014 Paien: Dae of Birh: 03/27/1971 Telephone: Ordering Physician: NourishBalanceThrive h S Ap 1 Oakland, CA Age: Sex: Reprined: Commen: 43 Female Fax: Mehodology: LC/Tandem Mass Specroscopy, Colorimeric This repor is no inended for he diagnosis of neonaal inborn errors of meabolism. Ranges are for ages 13 and over Nurien Markers Resuls mcg/mg creainine 95% Reference Range Fay Acid Meabolism (Carniine & B2) Adipae 7.3 H <= Suberae 1.5 <= Ehylmalonae 1.6 <= 6.3 Carbohydrae Meabolism (B1, B3, Cr, Lipoic Acid, CoQ10) Pyruvae 4.4 H L-Lacae 19.0 H 6. ß-Hydroxybuyrae Energy Producion (Ciric Acid Cycle) (B comp., CoQ10, Amino acids, Mg) Cirae Cis-Aconiae 91 H Isocirae 172 H 2.1 <= a-keogluarae 38.2 H <= Succinae 2.6 <= Fumarae Malae 7.3 H <= Hydroxymehylgluarae 7.6 H <= <= <= 1.35 CLIA ID# 11D Tesing Performed by Genova Diagnosics, Inc Corporae Way, Duluh, GA Florida Clinical Lab Lic. # Page 1 Laboraory Direcor: Rober M. David, PhD

5 Ordering Physician: Commen: Dae of Repor: 06/13/2014 Reprined: Mehodology: LC/Tandem Mass Specroscopy, Colorimeric This repor is no inended for he diagnosis of neonaal inborn errors of meabolism. Ranges are for ages 13 and over B-Complex Viamin Markers (B1, B2, B3, B5, B6, Bioin) 15. a-keoisovalerae Resuls mcg/mg creainine % Reference Range <= a-keoisocaproae <= a-keo-ß-mehylvalerae 0.38 <= Xanhurenae 0.56 H <= ß-Hydroxyisovalerae 11.9 H <= 11.5 Mehylaion Cofacor Markers (B12, Folae) Mehylmalonae 0.5 <= Formiminogluamae 1.8 H <= 2.2 Cell Regulaion Markers Neuroransmier Meabolism Markers (Tyrosine, Trypophan, B6, anioxidans) Vanilmandelae 0.9 L Homovanillae Hydroxyindoleaceae 67.6 H Kynurenae 1.1 H <= Quinolinae 2.5 <= Picolinae 3.3 Oxidaive Damage and Anioxidan Markers (Viamin C and oher anioxidans) p-hydroxyphenyllacae 2.57 H <= Hydroxy-2-deoxyguanosine 6.3 H <= 7.6 (Unis for 8-hydroxy-2-deoxyguanosine are ng/mg creainine) CLIA ID# 11D Tesing Performed by Genova Diagnosics, Inc Corporae Way, Duluh, GA Florida Clinical Lab Lic. # Page 2 Laboraory Direcor: Rober M. David, PhD

6 Ordering Physician: Commen: Dae of Repor: 06/13/2014 Reprined: Mehodology: LC/Tandem Mass Specroscopy, Colorimeric This repor is no inended for he diagnosis of neonaal inborn errors of meabolism. Ranges are for ages 13 and over Toxicans and Deoxificaion Resuls mcg/mg creainine 95% Reference Range Deoxificaion Indicaors (Arg, NAC, Me, Mg, anioxidans) Mehylhippurae <= Oroae <= Glucarae 7.6 H <= a-hydroxybuyrae 3.2 H <= Pyrogluamae 63 H Sulfae 4709 H Compounds of Bacerial or Yeas/Fungal Origin Bacerial - general 36. Benzoae Hippurae 560 H <= Phenylaceae <= Phenylpropionae p-hydroxybenzoae 1.1 <= p-hydroxyphenylaceae 34 H <= Indican 65 H <= <= 9.3 <= Tricarballylae <= 1.41 L. acidophilus / general bacerial D-Lacae 4.9 H <= 4.3 Closridial species 45. 3,4-Dihydroxyphenylpropionae Yeas / Fungal D-Arabiniol 71 H <= 73 Creainine = 32 mg/dl * <DL = less han deecion limi ** >LIN = greaer han lineariy limi CLIA ID# 11D Tesing Performed by Genova Diagnosics, Inc Corporae Way, Duluh, GA Florida Clinical Lab Lic. # Page 3 <= 0.05 Laboraory Direcor: Rober M. David, PhD

7 Ordering Physician: Commen: Dae of Repor: 06/13/2014 Reprined: Mehodology: LC/Tandem Mass Specroscopy, Colorimeric Supplemen Recommendaion Summary Wih knowledge of a paien's full medical hisory and concerns, he Organix Comprehensive Profile laboraory resuls may be used o help healhcare professionals creae an individually opimized nuriional suppor program. Based sricly on he resuls from his es, he summary able below shows esimaes of nurien doses ha may help o normalize nurien-dependen meabolic funcions. Cusomized Viamin and Mineral Formulaion Nuriens lised in his secion are normally conained in a muli-viamin preparaion. "Base" amouns may be used o ensure healh even when no abnormaliies are found. Nurien Viamin A* B-Caroene* Viamin C Viamin D* Viamin E Viamin K* Thiamin (B1) Riboflavin (B2) Niacin (B3) Pyridoxine (B6) Folic Acid (or 5-Mehyl-THF) Viamin B12 Bioin Panohenic Acid (B5) Calcium cirae Iodine* Magnesium Zinc* Selenium Copper Manganese* Chromium Molybdenum* Boron* Base 2500 IU 5500 IU 250 mg 400 IU 100 IU 100 mcg 5 mg 5 mg 25 mg 15 mg 400 mcg 50 mcg 100 mcg 25 mg 500 mg 75 mcg 250 mg 15 mg 100 mcg 1 mg 5 mg 200 mcg 25 mcg 1 mg Daily Amouns Unis Added 3000 mg 800 IU 20 mg 10 mg 20 mg 100 mg 800 mcg 500 mcg 1000 mcg 50 mg 50 mcg * Nuriens wih an aserisk are no modified based on he Organix es resuls. MM03 CLIA ID# 11D Tesing Performed by Genova Diagnosics, Inc Corporae Way, Duluh, GA Florida Clinical Lab Lic. # Page 4 Laboraory Direcor: Rober M. David, PhD

8 Ordering Physician: Commen: Dae of Repor: 06/13/2014 Reprined: Mehodology: LC/Tandem Mass Specroscopy, Colorimeric Oher Iems Indicaed for individual supplemenaion Various condiionally essenial nuriens and oher poenially beneficial inervenions appear in his secion only if relevan abnormaliies are presen. These ingrediens are no included in he cusomized viamin formula on he previous page. Nurien L. acidophilus srains conraindicaed Anifungals Arginine Carniine Coenzyme Q10 Glycine Lipoic Acid N-Aceylcyseine Need for oher anioxidans Tyrosine Amoun As needed 500 mg 400 mg 60 mg 4000 mg 600 mg 750 mg Srong 500 mg CLIA ID# 11D Tesing Performed by Genova Diagnosics, Inc Corporae Way, Duluh, GA Florida Clinical Lab Lic. # Page 5 Laboraory Direcor: Rober M. David, PhD

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