3 PER 6 PER. What is Collagen? Why choose. Try it and feel the difference! 1 kda. Better results! 3 to 5 kda. It s not how much you take...

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2 Why choose AminoLock Collagen has the lowest molecular size peptides in the world, at less than 1 kda providing the benefit of superior bioavailability and proven effectiveness for joint health* It s not how much you take... Other standard collagen brands 3 PER DAY 1 kda VS 6 PER DAY 3 to 5 kda it s how much you absorb! Smaller molecule = Superior Absorption Bigger molecule = Lower Absorption Better results! What is Collagen? Collagen is the fibrous structural protein that makes up the white fibres of joints, skin, tendons, bones, cartilage and all other connectives tissues. The production of collagen in the body slows down insidiously with age. Genacol is a safe substance that supplies the necessary elements in order to nutritionally support the body s production of collagen. It helps to: Maintain healthy joints* Relieve joint discomfort* Protect against cartilage deterioration and joint tissue degeneration* Improve mobility and flexibility of joints* Try it and feel the difference! Genacol continuously invests in scientific research to improve the health benefits of our products. As a dominant player in the industry, we believe it s important to continually surpass ourselves so we can offer the best products available on the market. Genacol s proprietary Aminolock Sequence Technology, the result of many years of research, helps improve absorption and thereby maximizes the beneficial effects*. The proof of the effectiveness in using Genacol s unique Very Low Molecular Weight AminoLock Collagen is now patent pending in the USA (Application number 62/426,908) and Canada (Application number ). Genacol ensures you to find: Proven effectiveness, supported by three published clinical studies Products to support joint, cartilage and bone health and help sleep* Smaller dosage requirements compared to other brands Highest quality of Collagen on the market - winner of 6 consecutive Consumer s Choice Award.

3 Reliability Patent-Pending Technology The proof of the effectiveness in using Genacol s unique very low molecular weight AminoLock Collagen is now patent pending. NON-GMO Our products are NON-GMO certified. #1 Absorbable form of Collagen AminoLock Collagen has the lowest molecular weight in the world, allowing superior bioavailability*. Supported by 3 clinical studies The effectiveness of AminoLock Collagen for joint health* is supported by three published and internationally recognized clinical studies. Collagen made in USA Genacol s AminoLock Collagen is produced in Sunflower, Mississippi, USA. The proof is in third party testing Dr. Haddad, PhD Scientific Consultant and Phamacologist Genacol continually invests in research that demonstrates the benefits of our joint supplements. Three published and internationally recognized clinical studies have provided scientific confirmation that Genacol helps to maintain healthy joints. These clinical studies can be fully reviewed on our website (genacol.com). BRUYERE study The first study was conducted over a six-month period at the University of Liege and included 200 subjects, aged 50 and over, who suffered from joint discomfort. The objective of the study was to demonstrate the efficacy of AminoLock Collagen (1200 mg) in maintaining healthy joint*, as compared to a placebo. PARM study Gluten-free Our products do not contain any gluten. The cattle used to produce our collagen are pasture-raised and grass-fed. Available worldwide Our products are sold in more than 40 countries, making Genacol the #1 collagen brand for joint health in the world! cgmp certified Our products are made in an FDA regulated plant that is cgmp and HACCP certified. The second study was conducted at Veterans Memorial Medical Centre in the Philippines. The objective of the study was to demonstrate the efficacy of AminoLock Collagen in maintaining healthy joint*, as compared to a nonsteroidal anti-inflammatory drug. The study was conducted over a six-month period and included 113 patients. SUAREZ study The third clinical study was conducted at the University of Santo Tomas Hospital in the Philippines. The objective of the study was to determine the efficacy of AminoLock Collagen, combined with physical exercise, in helping to maintain healthy joint*. The placebo-controlled, triple-blind study included 109 subjects, aged 50 and older, who had experienced knee discomfort for over a month. Recently, ConsumerLab.com, an independent organization that evaluates nutritional products in the USA, recognized Genacol s clinical study as: ONE OF THE LARGEST STUDIES ABOUT COLLAGEN HYDROLYSATE.

4 CAPSULES AminoLock Collagen Helps to maintain healthy joints* Original Formula since 2000! Genacol Original is made with 100% AminoLock Collagen using a unique technology that minimizes collagen s molecular weight to less than 1 kda to maximize absorption by the body. Genacol Original protects against cartilage deterioration and supplies the amino acids contributing to the formation of cartilage. It also helps maintain supple and flexible joints, and relieves joint discomfort and stiffness. Serving Size 3 capsules Servings Per Container 30 Amount Per Serving % Daily Value** Calories 5 Protein 2 g 4% Hydrolyzed collagen from bovine (1) source 1200 mg ** Percent Daily Values are based on a 2000 calorie diet. (1) Other ingredients: gelatin, vegetable magnesium stearate. 90 capsules and 180 capsules bottles available! Further to meeting the industry s highest manufacturing standards, AminoLock Collagen has no adverse effects, is GMO-free, and comes from pasture-raised animals. Dosage (adult): Take 3 capsules once daily, ideally at bedtime, or as directed by your health care practitioner. ORIGINAL ORIGINAL The liquid solution for joints! Original Liquid Fast absorbing liquid formula! Helps to maintain healthy joints* Genacol Original Liquid Formula is designed and formulated to maintain joint health in a natural way, and has the added benefit of fighting pill fatigue. Easy to use, this product is ideal for people with an active lifestyle. Faster absorption: the body more quickly absorbs the liquid formula. Genacol Original Liquid Formula is made with 100% AminoLock Collagen using a unique technology that minimizes collagen s molecular weight to less than 1 kda to maximize absorption by the body. Dosage (adult): Pour 15 ml in the measuring cup and mix with water or juice, once daily. Serving Size 15 ml Servings Per Container 30 Amount Per Serving % Daily Value** Calories 5 Protein 2 g 4% Hydrolyzed collagen from bovine (1) source 1200 mg ** Percent Daily Values are based on a 2000 calorie diet. (1) Other ingredients: purified water, erythritol, citric acid, green apple flavor, sodium benzoate, potassium sorbate, stevia. LIQUID FORMULA

5 LIQUID FORMULA The most complete joint formula available! Helps to maintain healthy joints* Helps lubricate and protect joints* Genacol Optimum is one of the most complete joint formula available. AminoLock Collagen, Glucosamine, Chondroitin, and MSM are essential ingredients to maintain joint health. Impressive joint health results are achieved because of the combination of the 4 natural active ingredients. Serving Size 15 ml Servings Per Container 30 (1) Other ingredients Amount Per Serving % Daily Value** Calories 15 Protein 2 g 4% Hydrolyzed collagen from bovine (1) source 1200 mg Glucosamine sulfate (Crab and shrimp exoskeleton) 1500 mg Chondroitin sulfate 500 mg MSM (methylsulfonylmethane) 400 mg ** Percent Daily Values are based on a 2000 calorie diet. Genacol Optimum s liquid form facilitates its absorption by the body, helps fight «pill fatigue», and is ideal for people who wish to live an active lifestyle while maintaining and preserving optimal joint health. Genacol Optimum supports healthier and stronger ligaments and tendons and promotes healthy joints and connective tissues. Dosage (adult): Pour 15 ml in the measuring cup and mix with water or juice, once daily. OPTIMUM The best combination! PLUS Original Liquid Helps to maintain healthy joints* Helps lubricate and protect joints* Genacol Plus is a product specifically designed for joint health. The collagen-glucosamine combination is the winning formula when it comes to ensuring good joint function and health. Combined with glucosamine, which helps lubricate and protect joints, Genacol Plus made with AminoLock Collagen is the perfect 2-in-1 product, and provides excellent value for money. Genacol Plus helps maintain supple and flexible joints, and relieves joint discomfort and stiffness. Dosage (adult): Take 3 capsules once daily, ideally at bedtime, or as directed by your health care practitioner. Serving Size 3 capsules Servings Per Container 30 Amount Per Serving % Daily Value** Calories 5 Protein 2 g 4% Hydrolyzed collagen from bovine (1) source 1200 mg Glucosamine hydrochloride (Crab and shrimp exoskeleton) 1500 mg ** Percent Daily Values are based on a 2000 calorie diet. (1) Other ingredients: gelatin, vegetable magnesium stearate. CAPSULES

6 The most complete formula on the market! Sleep better, move better! Original Liquid CAPSULES Supports bone strength* Helps to maintain healthy joints* This innovative product is made up of a unique blend of several nutrients and vitamins to maintain strong bones and healthy joints. Genacol Bone & Joint s exclusive formula contains Boron and 1000 IU of Vitamin D 3 to optimize the absorption of calcium also present in the capsules (600 mg / daily dosage). Serving Size 3 capsules Servings Per Container 30 Amount Per Serving Calories 5 Protein 2 g 4% Hydrolyzed collagen from bovine (1) source 1200 mg Boron 250 mcg Calcium (elemental) 600 mg 60% Vitamin D IU 250% Magnesium 50 mg 13% Manganese 1.8 mg 90% Vitamin K 1 20 mcg 25% Zinc 7.5 mg 50% Copper 1 mg 50% ** Percent Daily Values are based on a 2000 calorie diet. % Daily Value** (1) Ingredients: Hydrolyzed collagen from bovine (1) source, calcium carbonate, cholecalciferol (Vitamin D3), phytonadione (Vitamin K1), magnesium oxide, zinc oxide, copper sulfate, manganese sulfate, boron citrate, vegetable magnesium stearate, gelatin. Genacol Bone & Joint also contains AminoLock Collagen, which maintains supple and flexible joints, and relieves joint discomfort and stiffness. With Genacol Bone & Joint you have a powerful nutritionnal support for bone and joint health. Dosage (adult): Take 3 capsules once daily or as directed by your health care practitioner. BONE & JOINT Helps to maintain healthy joints* Helps to increase duration of sleep for occasional sleeplessness* Genacol Sleep & Joints is a unique combination of AminoLock Collagen and melatonin (the body s sleep hormone), which is largely responsible for the quality and duration of sleep. Genacol Sleep & Joints is a natural sleep aid, does not create dependence or grogginess upon waking, does not procure any undesirable side effects and is 100% drug free. It can greatly help people who occasionally suffer from occasional sleeplessness. Genacol Sleep & Joints has been specifically designed to promote a more restful night s sleep while improving joint health. Dosage (adult): Take 3 capsules once daily at bedtime, or as directed by your health care practitioner. SLEEP & JOINTS Serving Size 3 capsules Servings Per Container 30 Amount Per Serving % Daily Value** Calories 5 Protein 2 g 4% Hydrolyzed collagen from bovine (1) source 1200 mg Melatonin 9 mg ** Percent Daily Values are based on a 2000 calorie diet. (1) Other ingredients: gelatin, vegetable magnesium stearate. CAPSULES

7 NEW PRODUCT! NEW PRODUCT! Powerful anti-inflammatory and antioxidant*! Support joint health* Powerful anti-inflammatory and antioxidant* Genacol Joint & Mobility combines two exclusive ingredients : Aminolock Collagen and Soluble Eggshell Membrane. They are clinically proven to offer quick joint relief by regenerating your joints and reducing inflammation*. Genacol Turmeric Collagen Formula with BioPerine and Curcuma Longa (with 95% standardized Curcuminoids) is the perfect daily boost to promote healthy joints*. Soluble Eggshell Membrane contains glucosamine, chondroitin, hyaluronic acid and collagen which act as a powerful anti-inflammatory. AminoLock Collagen helps to maintain healthy collagen level in the body and support healthy joint in a safe and natural way*. Its Tumeric / Curcuma antioxidant and anti-inflammatory properties combined to AminoLock Collagen rejuvenating action will help ease joint discomfort and inflammation*. BioPerine, a black pepper extract, acts as natural bioavailability enhancer. It helps to improve the uptake of curcumin by 20x** to maximise it s benefits for health. Dosage (adult): Take 3 capsules once daily or as directed by your health care practitioner. Serving Size : 3 capsules Servings Per Container : 30 Amount Per Serving % DV Hydrolyzed collagen (from bovine) Eggshell membrane (from chicken) 5 1,2 g 450 mg Other ingredients: Gelatin, cellulose, vegetable magnesium stearate. Contains : Eggs ITY L I OB M Dosage (adult): Take 3 capsules once daily or as directed by your health care practitioner. TURM ER AMIN OL IC OC K IN UM RC LAGEN CU COL Calories JOIN T& CAPSULES Get joint relief in as little as 5 days!* Support joint comfort and mobility* Serving Size : 3 capsules Servings Per Container : 30 Amount Per Serving % DV Calories 5 Hydrolyzed collagen (from bovine) 1,2 g Turmeric (Rhizome) Extract (Curcuma Longa) (Standardized to 95% curcuminoids) 180 mg Black pepper (Fruit) Extract (Standardized to 95% piperine) 10 mg Other ingredients: Gelatin, vegetable magnesium stearate, silica CAPSULES Original Liquid

8 What About Collagen? What is Collagen? 1 3 What is the Importance of Collagen in the Body? Collagen is a hard, insoluble, and fibrous protein that makes up onethird of the protein in the human body. It is composed by a high level of the key amino acids : glycine, proline and hydroxyproline. These represent around 50% of the total amino acid content of collagen. Collagen structure is a triple helix of alpha-chains of 19 amino acids. Collagen is part of the natural composition of skin, tendons, bones, cartilage, and all other connective tissues. Collagen also gives to different organs and tissues their strength and elastic properties. COLLAGEN DISTRIBUTION IN THE BODY (by weight ratio of dry mass) 75% Skin Non essential amino acids Proline / Hydroxyproline 12% Other essential amino acids 6% Muscles 25% 30% 16% Bones 80% 8% Alanine Ligaments 20% 8% 11% Glycine 90% 67% Cartilage Tendons Arginine Glutamic Acid This structural protein plays a fundamental role in holding the body together. It constitutes most of the body s structural support and is the primary substance of connective tissues. Collagen, together with elastin and glycoproteins, is responsible for the cohesion of tissues and organs. It also gives these tissues and organs hydration, resistance, elasticity and flexibility properties. Besides its numerous structural properties, collagen serves as well as a main catalyst for growth and it repairs almost all the tissues of the body. It is also found widespread in the gelatinous substances of the body to provide stiffening properties, such as in the vitreous humour of the eye. Twenty-five percent of the protein weight in the human body and seventy-five percent of our skin are made of collagen. In other words, collagen is this fibrous connective tissue that holds our body together and is acting as the glue of the body.

9 Collagen in Joint Structure Collagen in Joint Structure Joints exist wherever two bones meet. They play a key role to ensure smooth and safe movements between the bones involved. Joints must thus deal with two major forces, namely load (including shock absorption) and friction. Synovial fluid present in the joint space acts as a hydraulic cushion in this context. Joints are mainly composed of : Muscle and Bones Articular Cartilage Tendons Ligaments Synovial Membrane and Fluid These different parts of the joint are mainly composed of collagen. Collagen Decrease 67% Cartilage Percentage of collagen in joint structure 90% Tendons 80% Ligaments When there is a decrease of collagen production in the body, everything is affected. Weakness, overall lack of energy, stiffness and discomfort are the main symptoms of a collagen decrease. In addition, all these symptoms increase with aging. In fact, collagen production begins to decline as early as age 30 and this reduction becomes much more prominent from age 50 and onwards. Even more ironically, in our early thirties, most of us accept to live with most of these minors discomforts. However, as far as the reduction of collagen in our body is concerned, these problems are just the tip of the iceberg; as they announce, together with aging, direct effects on our health and quality of life. Effects of Collagen Reduction on Joints Collagen decrease affects all our body tissues and organs. This phenomenon creates, in joint structure, a reduction of functions and a loss of resistance, elasticity and flexibility. This generates, in the short or medium term, a series of reactions that for most of us emerge as follows: Joint discomfort or stiffness Cartilage deterioration Joint tissue degeneration Ligaments and tendons weakness of injuries What are the benefits of Genacol AminoLock Collagen? In order to reduce the effects of collagen decrease, providing hydrolyzed collagen supplements to your body is the key. It has been acknowledged that Genacol AminoLock Collagen supplies amino acids that contribute to the maintenance of collagen in the body. Moreover, three independent studies have provided scientific confirmation that Genacol AminoLock Collagen helps to maintain healthy joints in a safe and natural way. It helps to: Relieve joint discomfort* Protect against cartilage deterioration* Preserve joint tissue from degeneration* Improve mobility and flexibility of joints* Which Collagen Type (I II III IV - V) is Genacol AminoLock Collagen? When it comes to collagen supplement, it is not the type or source of collagen hydrolysate that is important. It is the combination of the molecular weight (for bioavailability and absorption) and the specific mix of enzymes used in the production process in order to obtain a specific amino acid profile that matters.

10 Genacol AminoLock Collagen Difference Why is Genacol AminoLock Collagen Different? The lowest molecular weight you have, the superior absorption by the body you will obtain. As molecular weight directly impacts bioavailability, Genacol has developed an exclusive and optimal preparation of hydrolyzed collagen called the AminoLock Sequence Technology. The average size of commercially available hydrolyzed collagen generally varies between 6 and 10 kda. In contrast, thanks to the AminoLock Sequence Technology, the controlled enzymatic hydrolysis process produces peptide fragments of more uniform size which are smaller than 1 kda. Moreover, this technology enables Genacol to ensure its AminoLock Collagen contains well-established proportions of key amino acids required to promote collagen production in the body and to give an optimal outcome. In fact, it would take up to 5 to 10 times more of a standard hydrolyzed collagen product to obtain an equivalent concentration of certain amino acids and peptide fragments present in Genacol AminoLock Collagen. Medical grade laboratories The entire manufacturing process and quality control criteria respect the most rigorous standards in the industry. Our products are manufactured under medical grades according to the highest biotech standards and comply with all government requirements, which are regulated by the FDA and GMP and HACCP certified. The stainless steel equipment and self-contained CIP (Clean In Process) system ensure our products cleanliness and traceability. This entire process assures that we can offer a high-quality, reliable and efficient products to our customers. Unique manufacturing process The molecular weight profile of the collagen hydrolysate is dependent on the raw materials and especially the manufacturing process used. Depending on the chosen enzymatic hydrolysis, which is unique to our AminoLock Sequence Technology, a collagen hydrolysate with a molecular weight within a specified range can be obtained. COLLAGEN ENZYMATIC HYDROLYSIS Native Collagen (bovine source) HYDRO (H20) LYSE (BREAK, CUT) Enzymatic Hydrolysis Fragments of 5 to 30 amino acids (polypeptides) The processes involved in processing Genacol AminoLock Collagen are first demineralization, extraction of collagen to gelatine, enzymatic hydrolysis to obtain hydrolysed collagen by hydrolysis of peptide bonds of the gelatine molecules, ion exchange, filtration (such as membrane filtration technique), evaporation, sterilization and finally drying. In order to achieve the desired result, a specific mix of enzymes is sequentially used (AminoLock Sequence Technology). The choice and order of application of the chosen enzymes, together with reaction duration, ph and temperature will allow to obtain a specific collagen hydrolysate called Genacol AminoLock Collagen. The molecular weight distribution is then verified and determined on each production lot by such as means of gel permeation chromatography. The molecular weight distribution lower than 1 kilodalton (kda) is Genacol AminoLock Collagen hydrolysate.

11 About us... Mission Our mission is to offer all men and women concerned about their joint health the best innovative products in terms of safety, quality and efficiency. Our three clinical studies, along with our patent pending technology, prove that our products are unique, innovative, different and efficient. Responding to our customers needs is our passion and continuous commitment. We are dedicated to the well-being of our customers through their joint health and healthy aging. Our credo: To achieve excellence in harmony. A family story... Guy Michaud, Genacol s founder, is the architect behind the best collagen for joint health on the market! In the mid-1990s, a research and development company located in Montreal discovered the virtues of collagen hydrolysate as a natural supplement to improve joint health. In October 2000, Genacol Original Formula, made of 100% Genacol s AminoLock Collagen was launched. Very quickly, this innovative product was an indisputable success because of it s effective results on joint health. It became only a few years later a leader of its category. Over the years, Genacol was recipient of several important awards such as the Entrepreneur of the Year Ernst and Young award in the Health and Science category and has also received the first position in health in the magazine Profit 100 for its progress between 2004 and Genacol, proud leader in its field for more than 17 years, continues to innovate, with the goal of offering its customers effective, new products. With three independent scientific studies demonstrating the beneficial effects of its proprietary AminoLock Collagen, Genacol filed a patent application in Canada and the United States in early Although their products are now available in over 40 countries, Genacol remains a human-size family-owned company dedicated to the well-being of customers through their joint health. With Martin Vidal, President and Chief Executive Officer and Guy Michaud s sons now leading the company, they now focuses on the international market, research and development of new innovative natural health products, making Genacol the number one collagen brand for joint health company in the world!

12 Your Genacol products retailer: Genacol International Corporation Inc. Toll free: genacol.com

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