NUTRIMENTHE EU Project Effect of Diet on Mental Performance of Children FP7-KBBE , GA:

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1 NUTRIMENTHE EU Project Effect of Diet on Mental Performance of Children FP7-KBBE , GA: Prof. Cristina Campoy Department of Paediatrics, University of Granada NUTRIMENTHE Coordinator

2 Participan t No: PARTICIPANTS Participant Organisation Name 1 University of Granada (Coordinator) 2 University of Munich 3 UNILEVER 4 Erasmus University Medical Center 5 University Rovira I Virgili 6 University of Surrey 7 University of Pécs 8 University Degli study di Milano 9 University of Warsaw 10 Birmingham Children s Hospital The Children s Memorial Health Institute. Warsaw Research Institute Hospital Marqués de Valdecilla, Santander Institute for Market Research, Strategy and Planning 14 Université Libre de Bruxelles 15 SHS International 16 University of Bristol 17 GSF National Research Centre, Munich 18 Beta Technology Limited 19 Martek Bioscience 20 Neuron BPh

3 CHOPIN QLK EUROPEAN PROJECT 5 th Framework Programme QLK-CT

4 Mother s diet influences Prenatal-Postnatal intervention CHILDREN nutritional intervention WP1 WP2 WP3 WP4 WP5 WP6 WP10 WP11 Generation R ALSPAC NUHEAL CHOP Cognitive effect of nutrients WP 7 NEUROPSYCHOLOGICAL BATTERY PKU Consumers Economic impact WP 8 GENETIC POLYMORPHISMS WP 9 BIOANALYTICS Children 3-5 y Children 7 y WP 12 MANAGEMENT WP 13 DISSEMINATION, TRAINING Children up to 9.5 y Children up to 8.5 y Children 7-9 y Children 7-9 y Epidemiological studies Nutritional interventions

5 long term mental health Adulthood incidence of mental disorders brain function nutritional status How NUTRIMENTHE address long term mental health food technology neuropsychology RCT/follow-up genetics epidemiology consumer and economic science Childhood

6 OBJECTIVES (I) I. Quantify the effects of prenatal maternal diet on early programming, and subsequently on later cognitive development, mental and behavioural disorders (WPs 1-3). II. Understand the role and mechanisms of how specific nutrients affect mental performance, by virtue of genetic polymorphisms, in i genes encoding fatty acid and 5-methyl methyl-tetrahydrofolate tetrahydrofolate metabolism (WP1-6, 8). III. III.Understand how nutrition/diet of the mother, infant and child influence the child's neurodevelopment, mental performance and behavioural disorders (WPs 1-6). IV. IV.Explore the quantitative requirements and role of some nutrients in improving mental performance in children and their subsequent outcomes (WPs 5, 6).

7 OBJECTIVES (II) VI. Develop an appropriate standard neuropshycological battery to improve a comparable methodology for cognitive assessment of children in the EU (WPs 1-4, 6, 7). VII. VII.Explore how increasing knowledge about the links between diet and mental development, influences consumer behaviour and impacts upon public health (WPs 10, 11). VIII. VIII.Quantify, on a European scale, the economic impact of improving mental function through specific nutrients (WPs 10, 11). IX. Provide access to research results, deliver training and learning opportunities across all EU Member States, including Accession Countries (WP 13).

8 MENTAL PERFORMANCE HARMONISATION ANTHROPOMETRY & PHYSICAL ACTIVITY DIET WORKING GROUPS DISSEMINATIO N

9 Training Activities 1. ENA GRANADA POSTGRADUATE SCHOOL 2009 Role of nutrition on brain development and behaviour (Granada, 1 st -4 th October 2009) Led by the Nutrimenthe Working Group of Mental Performance (Prof. Cristina Campoy) ENA GRANADA POSTGRADUATE SCHOOL NUTRENVIGEN-G+D FACTORS MASTER MEETING ROLE OF NUTRITION ON BRAIN DEVELOPMENT AND BEHAVIOUR Granada, 1-4 October, 2009

10 TRAININGS, WORKSHOPS AND MEETINGS 2. Participation of Nutrimenthe in the Commnet Meeting: European Food Science Day, (Brussels, 18/11/2009) Beta-Technology (UK) Lead by the Nutrimenthe Working Group of Dissemination

11 Training Activities 3. ANTHROPOMETRIC AND BODY COMPOSITION TRAINING, 21 st October 2009 Tarragona, Spain Lead by the Nutrimenthe Working Group of Anthropometry and Physical Activity Invited people: Jane Williams, PhD UCL Institute of Child Health, London

12 Training Activities 4.SYSTEMATIC LITERATURE REVIEW & METANALYSIS 21 st October 2009 Tarragona, Spain Lead by the Working Group of Mental Performance 5.PUBLIC ENGAGEMENT TRAINING, 23 rd October 2009 Tarragona, Spain Led by the Nutrimenthe Working Group of Dissemination 6.INTERACTION BETWEEN NUTRITION, GENETICS AND MENTAL PERFORMANCE Interactive activity meeting promoted by the NUTRIMENTHE`s Lead by Nutrimenthe Working Group of Mental Performance (Lanzarote, January 2010). Profs Golding, Koletzko & Campoy, Dr Emmett & Statistician Mr Steer with Dr Lattka by .

13 Training Activities TRAINING ON NEURODEVELOPMENTAL ASSESSMENT IN CHILDREN FOR NUTRIMENTHE WP3 NUHEAL FOLLOW UP 22 nd of January Excellence Centre for Paediatric Research. Centre for Biomedical Research. Granada (Spain) Lead by the Nutrimenthe Working Group of Mental Performance (Prof. Miguel Pérez) NUTRIMENTHE WORKING GROUP OF DIET TRAINING. Barcelona, 18 th of February, 2010 Lead by the Nutrimenthe Working Group of Diet (Prof. Pauline Emmet)

14 INTERNATIONAL CONFERENCE THE POWER OF PROGRAMMING, MUNICH, MAY th Biannual NUTRIMENTHE Meeting satellite to the International Conference The Power of Programming Symposium: Programming of neurodevelopment Integrated with Nutrimenthe Presentations of main speakers: C. Campoy, M. Hadders-Algra, H. Szajewska Abstract presentations: C. Granström

15 Nutrimenthe presented nine posters

16 ENA POSTGRADUATE SCHOOL 2010

17 OTHER ACHIEVEMENTS NUTRIMENTHE cited in Lancet!. Vol 7 August 2008 First Prize given by DiarioMédico-AWARD for Best Healthcare Ideas of the Year 2009 (Spain) 2 Nutrimenthe Newsletters(Beta Technology)

18 EXPECTED RESULTS Increased knowledge, including quantification, of the effects of nutrition on mental performance and mental illness, including assessments of risks and benefits of nutrition at various age groups. Sound scientific data to substantiate health and nutrition claims and to develop harmonised dietary recommendations for specific population groups (pregnant women, lactating mothers, infants & children). Cooperation and dialogue between different scientific disciplines, particularly between neuroscience, paediatrics, nutrition, food science and child psychology/psychiatry.

19 EXPECTED RESULTS The best available data and leverage from unique trials and (running) prospective studies in children at a suitable age to perform reliable cognitive/behavioural testing. Increasing the excellence and innovation potentials of the European nutrition research communities by means of stronger links to cognitive and neurosciences. Maximal impetus to maintain Europe s lead in this critical area of research by leading researchers in the field. Information on the social and economic costs related to diet and mental performances in Europe. Thorough training and dissemination of a new generation of internationally respected multi-disciplinary scientists in this research area.

20 External Advisory Board Prof. Tomas Paus (Chair) University of Toronto Prof. Dr. Olle Hernell (University of Ümea, Sweden) Prof. Dr. Wim H.M. Saris University of Maastricht EU-ETP Jan-Willem van Klinken, PhD Columbia University New York Marcella Rietschel, PhD University of Heidelberg (Germany) Elizabeth Isaacs, PhD Institute of Child Health UCL (UK) Mijna Hadders-Algra, PhD University of Gröningen The Netherlands

21 Nutrimenthe Project FUTURE EVENTS

22 REASEARCH WORKSHOP Critical micronutrients in pregnancy, lactation and infancy: Focus on folate, iron and iodine Obergurgl (Austria), Feb 2011 Irene Cetin (Milan), Luis Moreno (Zaragoza), Berthold Koletzko (Münich)

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24 NUTRIMENTHE INTERNATIONAL SYMPOSIUM (TO BE CONFIRMED)

25 20 th World Congress of Nutrition. September, Granada 2013 NUTRIMENTHE LAST MEETING GRANADA, SEPTEMBER 2013

26 Thank you very much for your kind attention!!