Biochemistry and biophysics

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1 COURSE DESCRIPTION CRD Field of study Training profile (general academic/practical) Year / Semester Nursing practical III/6 Specialization Subject offered in: Course (obligatory/optional) Nursing Polish obligatory No. of lecture hours: 5 No. of self-studying hours: 0 Cycle of studies: first Form of studies (full time/weekends) Full time Field of studies ECTS Medical sciences, health sciences and physical education Status of subject in curriculum (basic, specialized, other) Basic sciences (general academic, from other department) general academic Unit providing the : Institute of Health Sciences Lecturer in charge of the subject: dr Beata Dudzińska-Bajorek b.bajorek@pwsz-gniezno.edu.pl dr Marek Nowicki marek.nowicki@gmail.com Initial requirements in knowledge, skills, social competences: Knowledge: Skills: Basic knowledge in the field of biochemistry and biophysics bility to use current knowledge to ensure safety and a high level of care Social competences Has awareness of the factors affecting the patient's own and patient's reactions. Is aware of the need for permanent, lifelong learning. The aim of the subject: Understanding the biochemical processes conditioning life, the chemical structure of the constituents of the system and their transformations. Understanding the natural physiological, pathological and remedial processes. Training Knowledge s a result of the course a student is able to: Characterizes the specification and importance of water-electrolyte and acid-base management in maintaining the homeostasis of the regime; Defines the basic reactions of inorganic and organic compounds in.w5.++ aqueous solutions and the physical laws affecting the flow of liquids, as well as factors affecting vascular resistance of blood flow..w4.++ National Qualifications Framework/PWSZ Gniezno/08

2 Explains the fundamentals of physicochemical activities of the senses using physical media of information (sound and electromagnetic waves).w Determines the physical basis for non-invasive and invasive imaging methods Differentiates the construction of amino acids, nucleoside, monosaccharides, carboxylic acids and their derivatives, which are part of macromolecules present in cells, extracellular matrixes and body fluids, differentiate vitamins;.w7.++.w9.++ Skills s a result of the course a student is able to: Predicts the direction of biochemical processes in individual clinical states; Uses knowledge of the laws of physics to describe issues related to the biology of cells, tissues and physiological processes, in particular to explain the influence of external factors, such as temperature, gravity, pressure, electromagnetic field and ionizing radiation on the human body; Estimates the harmfulness of a dose of ionizing radiation and applies to radiological protection rules. Competences s a result of the course a student is able to:.u.++.u7.+++.u7.++ Systematically enriches professional knowledge and shapes skills, BCD.K + aiming to professionalism Reliably and accurately performs the entrusted professional duties BCD.K6 + bides professional secrecy BCD.K7 + ccepted grading criteria Local grade Local definition ECTS grade ECTS definition 5 Bardzo dobry [very good] perfect knowledge, skills, competences Celujący [exemplary] extraordinary achievements 4,5 Dobry plus [good plus] very good knowledge, skills, competences 4 Dobry [good] good knowledge, skills, competences B C Bardzo dobry [very good] above average standards with some mistakes Dobry [good[ general good work with some noticeable mistakes,5 Dostateczny plus [satisfactory plus] satisfactory knowledge, skills, competences but with significant shortcomings D Zadowalający [satisfactory] satisfactory but with significant mistakes National Qualifications Framework/PWSZ Gniezno/08

3 Dostateczny [satisfactory] satisfactory knowledge, skills, competences but with numerous shortcomings (threshold 60% of the requirements) Niedostateczny [insufficient] insufficient knowledge, skills and competences (below 60% of the requirements) E Dostateczny [satisfactory] meet minimal criteria FX, F Niedostateczny [insufficient] basic shortcomings in material ssumed grading methods Diagnosing assessment:. Knowledge test, e.g. Lecture or from a range of prerequisites Formative assessment:. Colloquial involving the subjects concerned.. Observing the student during the activities.. Evaluation of the class discussion. 4. Passing the sets of issues necessary for the practical assessment (conduct of the subject test, assessment of dexterity, carrying out a physical examination) 5. Evaluation of the prepared project. 6. Evaluation of the presentation. 7. Evaluation of other tasks performed by the student in accordance with the effects established in the Syllabus. Summative assessment:. Oral exams and transcripts-a list of issues subordinated to specific learning.. Examinations and written tests with the order for the specific learning.. In practical classes, professional practices, assessment of the implementation of learning based on the assessment of the effects of on practical lessons, the practical skills shown in the Diary of learning Outcomes 4. The diploma examination, which consists of a theoretical and practical part, includes the examination of the knowledge, practical skills and social competences gained throughout the period of study (annex III). Diploma exam rules). Curriculum content Lectures: Structure and functions of the main groups of organic compounds in the cell: proteins, carbohydrates, fats, nucleic acids. Biochemical processes determining life: catabolism and anabolism carbohydrates, fatty acids, proteins and nucleotides. Major metabolic pathways and metabolism control mechanisms. Vitamins, their structure, biochemical functions and role in the body. Regulate and integrate metabolism at cell, tissue and body level. Metabolic strategies. Exercises: Basic characteristic reactions of amino acids, proteins, simple and complex carbohydrates. Techniques for the distribution of biologically active substances: thin chromatography (TLC) and electrophoresis. National Qualifications Framework/PWSZ Gniezno/08

4 Self-studying:. Breakdown of enzymes into classes examples, isoenzymes, rybozymy. Coenzyme, their role, examples. Participation of vitamins in the building of coenzymes, effects of shortages and excess vitamins in the body 4. Sources of reactive oxygen species, enzymes removing toxic forms of oxygen-catalase, peroxidase glutathione, reductase Glutathione, superoxide dismutase and drobnocząsteczkowe compounds protecting the body from the toxic effects of oxygen 5. Respiratory regimen and organization in the internal mitochondrial membrane 6. Gluconeogenesis of lactate and glycerol reactions, tissue location, regulation, energy balance, enzymatic distinction between glycolyze and gluconeogenesis 7. Catabolism of chains of carbon amino acids leading to: acetyl-co and Krebs cycle metabolites, certain metabolic defects of catabolism amino acids phenylketonuria, Tyrosinemia, albinism, lkaptonuria 8. mmonia detoxification-urea synthesis and glutamine synthesis, urea cycle localization, enzymes, reactions, regulation, energy consumption, hyperammonemia 9. mino acids as a source of other biologically active compounds: creatine, nitric oxide, carnitine, thyroxine, Triiodothyronine 0. Synthesis and catabolism of heme, Porphyria, bilirubin formation, bilirubin-free-liver and conjugated-hepatic, bilirubin transformation products in the gastrointestinal tract, jaundice. Endogenous biosynthesis for human amino acids la, Gln, Glu, SP, Tyr, Gly, Ser, RG,, norepinephrine, adrenaline, dicarboxylic amino acids supplying amine biogenic-histamine, serotonin, ethanolamine, γ-aminobutyric acid. Hormones, their breakdown by chemical construction and site of formation, molecular mechanism of action of hormones connecting to intracellular receptors, plan to build intracellular receptor. Congenital metabolic diseases, disorders of the metabolism of amino acids m.in. Phenylketonuria, vitiligo, alkaptonuria, carbohydrates m.in. Galactosemia, congenital fructose intolerance, glycogen, lipid-m.in. Familial hypercholesterolemia, canthocytosis, changes in dyesporphyria Main bibliography: Biochemia J.M. Berg, J.L. Tymoczko, L. Stryer; Wydawnictwo Naukowe PWN Biochemia Harpera R. Murrey, D. Granner, P. Mayes, V. Rodwell: PZWL National Qualifications Framework/PWSZ Gniezno/08

5 Supplementary bibliography: Krótkie wykłady Biochenia B.D. Hames, N.M. Hooper; Wydawnictwo Naukowe PWN Biologia E.P. Solomon, L.R. Berg, D.W. Martin; Multico Podstawy biologii komórki B. lberts, D. Bray, K. Hopkin,. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter; Wydawnictwo Naukowe PWN Student s involvement Form of activity Hours ECTS Total number of hours 50 Hours requiring direct contact with a lecturer 5 ctivities requiring self-studying 0 National Qualifications Framework/PWSZ Gniezno/08

The University of Jordan. Accreditation & Quality Assurance Center. COURSE Syllabus

The University of Jordan. Accreditation & Quality Assurance Center. COURSE Syllabus The University of Jordan Accreditation & Quality Assurance Center COURSE Syllabus 1 Course title Biochemistry for Medical students 2 Course number 0501213 Credit hours (theory, practical) 3 3 Contact hours