Monitoraggio di Contaminanti Ambientali nella Catena Alimentare ed Effetti sulla Salute (CoAS PIAS) Gian Luigi Russo

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1 Monitoraggio di Contaminanti Ambientali nella Catena Alimentare ed Effetti sulla Salute (CoAS PIAS) Gian Luigi Russo Aula Marconi C. N. R. - ROMA 18 giugno 2009

2 Obiettivi del GdL CoAS-PIAS Environmental Contaminants Food-Chain Human Health For consumers, safety is the most important ingredient of their food. (Androulla Vassiliou, European Commissioner for Health)

3 Type of Food Contamination Environmental contaminants are substances that are present in the environment in which the food is grown, harvested, transported, stored, packaged, processed, and consumed. The physical contact of the food with its environment results in its contamination. Physical Extraneous bodies in food (plastics, wood, glass etc) Chemical Microbiological Heavy metals Pesticides Dioxins, PCB Bacteria Virus Parasites

4 Levels of Food Contamination Environmental contamination Agricultural contamination Vegetables Storage Ground contamination Industrial contamination Live stock Transformation Cooking Consumer Fishing 4

5 Food Contamination and Human Health Acute exposure (early effects) Melamine-contaminated powdered infant formula Melamine form stones and gravel in the urinary system. Stones can cause obstructive uropathy, and marked obstruction may cause acute renal failure Chronic exposure (long term) Heavy metals (As,Hg,Cd). Cancer, neurological disease, physical illness Fetal and infants exposure POPs (persistent organic pollutants). Developmental effects: damages to the nervous system, reproductive disorders, immunopathological states.

6 Chemical Contaminations

7 Food Quality and Safety WHO World Health Organization Food & Drug Administration EFSA European Food Safety Authority Ministero della Salute ISS Istituto Superiore Sanità ARPA, ASL, NAS and others

8 State of Art of Food Contamination in Europe and Italy (The Rapid Alert System for Food and Feed [RASFF] 2008)

9 Community Alert Notification on Food and Feed Contaminations (2008) Number of Notifications

10 Numbers of Notifications From European Countries 468

11 Types of Food Contaminations Microbiological and biological Chemical

12 Global Contamination Analysis Listeria Salmonelle Metalli pesanti Fitofarmaci Micotossine

13 Notification of Food Contamination: Food Products

14 Fishing Products Contamination

15 Meat Products Contaminatios

16 Product Contaminations Fruits and vegetables Oils and fats

17 Italian Products Contaminations

18 Heterogeneous Risk of Food Contamination in National Products

19 Contaminanti Ambientali Pesticidi Diossine e diossine-like Metalli pesanti Dieta Salute dell Uomo Banche biologiche: Bambini Adolescenti Adulti Campioni siero-urine Questionari alimentari Incidenza patologie Genotyping Ormesi Stress ossidativo Biodisponibilità Modelli Sperimentali Inter. Endocrini Pat. Tumorali Riproduzione Pat. Neurodegenerative

20 PESTICIDES IN THE PLATE 2009

21 Dioxins Cycle Cl O Cl O Cl Cl O Cl Cl Sources Fats

22 Heavy metals and human health Elemento Conc. mg/g Conc. mg/g in Food Se Cd Hg Pb Cu Zn

23 Group Members - CoAS Coordinator: Dr Gian Luigi Russo Research Associate: Dr Annalisa Mupo Dr Aurelio Giaretta Dr Giancarlo Cavazzini Dr Alfonso Siani Dr Paola Russo Dr Rosa Siciliano Dr Floriana Boscaino Dr Idolo Tedesco Dr Vincenzo Longo Dr MariaGrazia Andreassi Dr Elisabetta Tosti

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