TOTAL DEBRANCHING OF THE AORTIC ARCH! Julien GAUDRIC! Hôpital Pitié-Salpêtrière, Paris.!
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1 TOTAL DEBRANCHING OF THE AORTIC ARCH! Julien GAUDRIC! Hôpital Pitié-Salpêtrière, Paris.!
2 DISCLOSURES o NONE
3 TOTAL DEBRANCHING POOR SURGICAL RISK HYBRID TECHNIQUE Sternotomy Andersen N. JVS 2013 CHIMNEY TECHNIQUE No dedicated component to SAV Yoshida R. EJVES 2011 BRANCHED DEVICES Ishimaru S. JET 2004 Piffare< G. JVS 2013
4 CHIMNEY TECHNIQUES OFF THE SHELF «EASY TO USE» ONE OR MORE TRUNKS DURABILITY? ENDOLEAKS (GUTTERS)? Total endovascular Debranching of the aortic Arch. Yoshida R, Kolvenbach R et al.ejves 2011!
5 ! LITTERATURE REVIEW Article( Pt(No( Branches( assessed( Baldwyn(et(al.( 3! IA=3! (2008)( LCCA=0! Sugiura(et(al.( (2009)( 3! IA=3! LCCA=0! Feng(et(al.((2011)( 1! IA=1! LCCA=1( Cires(et(al.((2011)( 2! IA=2! LCCA=0! Yoshida(et(al.( 2! IA=2! (2011)( LCCA=2( Vallejo(et(al.( (2012)( 3! IA=3! LCCA=0! Shahverdyan(et( 6! IA=6! al.((2013)( LCCA=6( Synowiecz(et(al.( 1! IA=1! (2013)( LCCA=0! TOTAL( 21( IA=100%( LCCA=43%( Aortic( stentgraft( Chimney(Graft(type( Overlap( lenght( Technical( success( Gore!TAG! Luminex! N/D! 100%!! Gore!TAG! Wallstent+Luminex! Gore!TAG! Zilver+Wallstent! Gore!TAG! TFLE+Wallstent! N/D! 100%!! Cook!tho! TFLE+Wallstent! Cook!tho! TFLE+Wallstent! Bolton! Sinus!stent! N/D! 100%!! Relay!! N/D! Balloon!expandable! N/D! 100%!!! stents! Cook! TFLE!(IA)!Viabahn! 7cm( 100%!! proform! (LCC)! N/D! Viabahn+Wallstent! N/D! N/D! N/D! 100%!! Gore!TAG! Viabahn! 5cm( 100%!! N/D! Ballon!expandable! steel!stent! ( Bare(stent=39%( Covered(stent=61%( N/D! 100%!! ( 100%( ( Overall caracteristics of currently available articles on chimney-graft technique preserving supra aortic trunks in landing zone 0 stentgrafting.!
6 LITTERATURE REVIEW Article Complications Mortality Proximal Endoleak I CG perméability Follow- up (month) Baldwyn et al. Stroke (n =1) % <24m Sugiura et al (gutters) 100% 12m Feng et al % 12m Cires et al % 12m Yoshida et al % 17m Vallejo et al. N/D N/D N/D 100% N/D Shahverdyan et al Synowiecz et al. SCI (n=1) 1 5 (I prox, 2 gutters, 1 IA, 1 LCCA) 100% 2,5m % N/D TOTAL Stroke :5,5% SCI :5,5% 5,5% 33,3% 100% 13m
7 CHIMNEY TECHNIQUES Off the shelf endovascular approach «easy» because of no branches or fenestration catheterism Low morbidity rates BUT Small sample of patients Short term follow-up High endoleak rate? NO CONCLUSION ABOUT LONG TERM EFFICACY
8 SURGICAL DEBRANCHING
9 LITTERATURE REVIEW Carrel T (2005) Hughes (2006) Saleh H (2006) Bergeron P (2006) Zhou W (2006) Chan Y (2008) Chen I (2008) Wang S (2008) Weigang E (2009) Chiesa R (2010) Holt P (2010) Geisbusch P (2010) Canaud L (2010) Our serie (2013)! n Mortality J30 Stroke Aortic Dissection Paraplegia FU (month) Bypass permeability Endoleak I Technical succes N/D N/D 0 100% N/D N/D 0 100% N/D 100% 0 100% 15 1 (6,7%) 0 1 (6,7%) 1 (6,7%) % 1 (6,7%) 87% 8 1 (12,5) N/D N/D 0 100% % 0 100% N/D 0 N/D N/D 0 100% 4 0 N/D N/D 0 N/D N/D N/D N/D 26 4 (15,4%) 24 3 (12,5%) 1 (3,8%) 3 (12,5%) 0 0 N/D N/D N/D N/D % 1 (4,2%) 91,7% 9 1 (11,1%) N/D 100% 1 (11,1%) 97,4% 10 1 (10%) 0 N/D 0 36 N/D 3 (30%) 80% 6 0 MORTALITY= 8.46% ENDOLEAK TYPE I OR III= 3.97% 1 (16,5%) STROKE= 3.17% 1 (16,7%) 1 (16,7%) N/D N/D 0 100% 25 7 (28%) 2 (8%) 4 (16%) % 0 Litterature revew of total debranching in zone 0 for hybrid treatment of aortic arch desease.! 92%
10 PITIÉ-SALPÊTRIERE S EXPERIENCE From 1999 to 2012 High surgical risk (ASA 3) = 48%, mean log EuroSCORE= 35% Patients(caracteristics( n( %( Number(of(patients( 25(! Age((mean)( 75,5!y!! Sex((male/female)( 20!M/5!F!! ASA( 3( 12! 48%! Hypertension(n((%)( 21! 84%! Smoker(n((%)( 20! 80%! Diabetes(mellitus(n((%)( 6! 20%! Dyslipidémia(n((%)( 10! 40%! CAD(n(%)( Fangioplasty( Fcoronary(bypass( 12! 6! 2! 40%! 24%! 8%! COPD( 6! 20%! Mean(creat(clearance(( 62,5ml/mn!! Aortic(lesion( Faneurysm( Fsacciform(aneurysm(! 22! 3! (!!!! 88%! 12%!
11 PITIÉ-SALPÊTRIERE S EXPERIENCE Carrel T (2005) Hughes (2006) Saleh H (2006) Bergeron P (2006) Zhou W (2006) Chan Y (2008) Chen I (2008) Wang S (2008) Weigang E (2009) Chiesa R (2010) Holt P (2010) Geisbusch P (2010) Canaud L (2010) Our serie (2013)! n Mortality J30 Stroke Aortic Dissection Paraplegia FU (month) Bypass permeability Endoleak I Technical succes N/D N/D 0 100% N/D N/D 0 100% N/D 100% 0 100% 15 1 (6,7%) 0 1 (6,7%) 1 (6,7%) % 1 (6,7%) 87% 8 1 (12,5) N/D N/D 0 100% % 0 100% N/D 0 N/D N/D 0 100% 4 0 N/D N/D 0 N/D N/D N/D N/D 26 4 (15,4%) 24 3 (12,5%) 1 (3,8%) 3 (12,5%) 0 0 N/D N/D N/D N/D % 1 (4,2%) 91,7% 9 1 (11,1%) N/D 100% 1 (11,1%) 97,4% 10 1 (10%) 0 N/D 0 36 N/D 3 (30%) 80% (16,5%) 1 (16,7%) 1 (16,7%) N/D N/D 0 100% 25 7 (28%) 2 (8%) 4 (16%) % 0 92%
12 MORTALITY n=7 (28%) 1 pneumopathy 1 left ventricular guidewire perforation 1 hemorragic shock 2 strokes (consecutives to femoro-sav bypass) 2 type A dissection
13 MORTALITY n=7 (28%) 1 pneumopathy 1 left ventricular guidewire perforation 1 hemorragic shock 2 strokes (consecutives to femoro-sav bypass) 2 type A dissection
14 ! MORTALITY n=7 (28%) 1 pneumopathy 1 left ventricular guidewire perforation 1 hemorragic shock 2 strokes (consecutives to femoro-sav bypass) 2 type A dissection
15 Femoral artery as inflow? n=3 Previous history of Aorto Coronary Bypass Unfit for sternotomy Mortality n=2/3 (66%) NOT RECOMMANDED
16 Secondary type A dissection and debranching n=4 (16%) Mortality n=2 (50%) Proximal stent Debranching grai (proximal anastomosis) AorMc tear
17 CONCLUSION CHIMNEY TECHNIQUE Favorable results But endoleak rate? Best kind of device? Proximal overlap lenght 5cm HYBRID TECHNIQUE Long term stability Low rate of endoleaks High mortality rates High risk of type A dissecmon
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